Identidad local. Estrategias de ampliación de “la ruta del adobe”. Catamarca, Argentina.
Chaila, Josefina del Huerto; Carrizo, Maria Fernanda
La búsqueda de lo propio se contrapone al actual paradigma cultural global. Lacoexistencia de tiempos y formas de vida interrelacionados en un medioconvulsionado nos lleva a valorar lo autóctono como una reliquia y recuerdo de lo quenos identifica. El proceso de globalización en el que estamos inmersos tiende a lahomogeneización, esto provoca reacciones adversas tendientes a la búsqueda de lolocal. Las herramientas que nos brinda el turismo para tomar contacto y dar a conocerlo autóctono, nos lleva a buscar estrategias que posibiliten el conocimiento y lavaloración de los pueblos, sus costumbres, su organización social, la configuración ydisposición de la arquitectura civil y doméstica. La “ruta del adobe”, es un recorridoturístico conformado por viviendas vernáculas construidas con materiales y técnicastradicionales. La propuesta de ampliación parte de los siete iconos de arquitecturareligioso-civil y se expande tomando elementos de la arquitectura doméstica queconfigura el territorio. A lo largo del recorrido se evidencia la estrecha relación de laarquitectura vernácula con el entorno. Las construcciones tradicionales a lo largo delcamino, son el testimonio de la historia local y de las costumbres populares. El trabajopresenta estrategias para mantener los rasgos que caracterizan la identidad local a lolargo del camino del adobe en la provincia de Catamarca, ampliando el recorrido ypotencializando los beneficios turísticos derivados de esta acción. Conservar,preservar y fortalecer los elementos que lo conforman y sus características, tienden ala sustentabilidad de la identidad local.
The fumigant and repellent activity of aliphatic lactones against Pediculus human us capitis (Anoplura: Pediculidae)
Toloza, Ariel Ceferino; Zygadlo, Julio Alberto; Mougabure Cueto, Gastón Adolfo; Zerba, Eduardo Nicolás; Faillaci, Silvina Mabel; Picollo, Maria Ines
New alternative insecticides are necessary for the chemical control of head lice. In this study the fumigant knockdown time 50% (KT50) and repellency index (RI) of three aliphatic lactones was compared with two essential oils and DDVP, against permethrin-resistance Pediculus humanus capitis from Argentina. In the fumigant assay, none of the lactones were effective compared to the highest activity of eucalyptus (KT50 15.53 m). In the repellency test, the three lactones were equally or more effective (RI ranging from 60.50 to 76.68) than the positive control (piperonal). These lactones are promising as head lice repellents.
Familia, comercio y redes sociales : Dos familias a fines del período colonial
Quiñonez, Maria Mercedes
En este artículo nos centramos a fines del período colonial para analizar las trayectorias de Domingo Antonio Patrón y Francisco Manuel Costas, comerciantes que desde su llegada a la ciudad de Salta, en el último tercio del siglo XVIII, se insertan en la sociedad local y conforman redes de relaciones y vínculos en distintos circuitos económicos. Este estudio de caso nos permite recuperar, desde otra escala de análisis, la estructuración del grupo de los comerciantes, que constituyen a fines de la colonia una elite periférica o secundaria, y sus múltiples relaciones con la elite local tradicional, en una sociedad en transición. Además, nos permite ver los distintos caminos del ascenso social y económico en la sociedad tardocolonial; la permanencia de valores como el linaje y la propiedad de la tierra para la elite más tradicional, como los comerciantes que arriban en el período borbónico logran insertarse en ese entramado social y el papel que la riqueza– derivada del comercio– adquiere en esta sociedad. Las dos trayectorias analizadas presentan patrones diferentes de comportamiento de los comerciantes salteños, a fines del período colonial.
Hidrogeología de Argentina; Hydrogeology of Argentina
Auge, Miguel Pedro; Wetten, Cristian; Baudino, Guillermo; Bonorino, Alfredo Guillermo; Gianni, R.; González, N.; Grizinik, M.; Hernandez, Mario Alberto; Rodríguez, J.; Sisul, Ana Clara; Tineo, Alfredo; Torres, C.
Se mencionan las características hidrogeológicas de la República Argentina, en su ámbito continental que ocupa 2.800.000 km2 y otro que contiene a la Antártida Argentina, Islas Malvinas, Georgias, Sandwich, Orcadas y Shetland, del Sur, en 1.000.000 de km2 adicionales. Para la caracterización se subdividió al territorio en 18 regiones hidrogeológicas, sobre la base de la incidencia que ejercen en el agua subterránea, los componentes geológico, climático, geomórfico y biótico. Además, se citan los usos actuales del agua y los previstos en el futuro, como así también los conflictos derivados de su empleo. Finalmente se sintetiza el ordenamiento institucional y legal, referidos a los recursos hídricos.; The hydrogeologic behavior of the Argentine Republic is mentioned, in their continental environment that occupies 2,800,000 km2 and another that contains the Argentine Antartic and the islands of Malvinas, Georgias, Sandwich, Orcadas and Shetland, of the South (1,000,000 additional km2). For the characterization the territory was subdivided in 18 hydrogeologic regions, on the base of the incidence that exert in the groundwater, the geologic, climatic, geomorphic, and biotic components. The current uses of the water are mentioned and it forseen in the future, how so also the conflicts derived of their employment. Finally the institutional and legal arrangement referred to the water resources is synthesized.
CDW and CDW-EIS calculations for FDCSs in highly charged ion impact ionization of helium
Ciappina, Marcelo Fabián; Cravero, Walter Ruben
In this work we present fully differential cross sections (FDCS) calculations using CDW and CDW-EIS theories for helium single ionization by 100 MeV/amu and 2 MeV/amu C6+ and 3.6 MeV/amu Au24+ and Au53+ ions. We performed our calculations for different momentum transfers and ejected electron energies. We study the influence of the internuclear potential on the ejected electron spectra. We discuss different regimes where the internuclear interaction can or cannot be neglected. We compare our calculations with experimental data available. It is shown that for high impact energy and small momentum transfer, internuclear potential effects can be neglected in FDCSs.
Endogenous or exogenous coagulation factor level and the response to activated protein C
Gennari, Laura C.; Blanco, Alicia Noemi; Dominguez, Maria Paula; Grosso, Silvia H.; Lazzari, María Ángela
The abnormal response to activated protein C could be the mechanism to explain the prothrombotic role of elevated coagulation factor levels. We evaluated the effect of factor VIII, II, or X (FVIII, FII, or FX) levels on activated protein C resistance technique and its association with the resistant phenotype.
The biological sense of cancer: a hypothesis
Ruggiero, Raul Alejandro; Bustuoabad, Oscar David
Most theories about cancer proposed during the last century share a common denominator: cancer is believed to be a biological nonsense for the organism in which it originates, since cancer cells are believed to be ones evading the rules that control normal cell proliferation and differentiation. In this essay, we have challenged this interpretation on the basis that, throughout the animal kingdom, cancer seems to arise only in injured organs and tissues that display lost or diminished regenerative ability.
Amyloid-β peptide remnants in AN-1792-immunized Alzheimer's disease patients: A biochemical analysis
Patton, R. Lyle; Kalback, Walter M.; Esh, Chera L.; Kokjohn, Tyler A.; Van Vickle, Gregory D.; Luehrs, Dean C.; Kuo, Yu-Min; Lopez, John; Brune, Daniel; Ferrer, Isidro; Masliah, Eliezer; Newel, Amanda J.; Beach, Thomas G.; Castaño, Eduardo Miguel; Roher, Alex E.
Experiments with amyloid-β (Aβ)-42-immunized transgenic mouse models of Alzheimer's disease have revealed amyloid plaque disruption and apparent cognitive function recovery. Neuropathological examination of patients vaccinated against purified Aβ-42 (AN-1792) has demonstrated that senile plaque disruption occurred in immunized humans as well. Here, we examined tissue histology and quantified and biochemically characterized the remnant amyloid peptides in the gray and white matter and leptomeningeal/cortical vessels of two AN-1792-vaccinated patients, one of whom developed meningoencephalitis. Compact core and diffuse amyloid deposits in both vaccinated individuals were focally absent in some regions. Although parenchymal amyloid was focally disaggregated, vascular deposits were relatively preserved or even increased. Immunoassay revealed that total soluble amyloid levels were sharply elevated in vaccinated patient gray and white matter compared with Alzheimer's disease cases. Our experiments suggest that although immunization disrupted amyloid deposits, vascular capture prevented large-scale egress of Aβ peptides. Trapped, solubilized amyloid peptides may ultimately have cascading toxic effects on cerebrovascular, gray and white matter tissues. Anti-amyloid immunization may be most effective not as therapeutic or mitigating measures but as a prophylactic measure when Aβ deposition is still minimal. This may allow Aβ mobilization under conditions in which drainage and degradation of these toxic peptides is efficient.
Differential involvement of ERK1-2 and p38MAPK activation on Swiss 3T3 cell proliferation induced by prostaglandin F2alpha
Dekanty, Andres; Giulianelli, Sebastian Jesus; Coso, Omar Adrian; Rudland, Phillip S.; Jimenez de Asua, Luis Adan Felipe
Prostaglandin F2alpha (PGF2alpha) induces cyclin D1 expression and DNA synthesis in Swiss 3T3 cells. In order to assess which signaling mechanisms are implicated in these processes, we have used both a pharmacological approach and interfering mutants. We demonstrate that PGF2alpha induces extracellular-signal-regulated kinase (ERK1-2) and p38MAPK activation, and inhibition of any of these signaling pathways completely blocks PGF2alpha-stimulated DNA synthesis. We also show that ERK1-2, but not p38MAPK activation is required to induce cyclin D1 expression, strongly suggesting that the concerted action of cyclin D1 gene expression and other events are required to induce complete phosphorylation of retinoblastoma protein and S-phase entry in response to PGF2alpha.
Retinal dysfunction in patients with chronic Chagas’disease is associated to anti-Trypanosoma cruzi antibodies that crossreact with rhodopsin
Matsumoto, Silvia C.; Labovsky, Vivian; Roncoroni, Marcela; Guida, Maria Catalina; Gimenez, Luisa; Mitelman, Jorge; Gori, Horacio; Jurgelevicius, Renata; Grillo, Alejandro; Manfredi, Pablo; Levìn, Mariano J.; Paveto, Cristina
To investigate retinal involvement in chronic Chagas' disease, we performed electroretinography and retinal fluorescein angiography studies in chagasic patients. Our results demonstrated a dissociated electrophysiological response characterized by both an abnormal reduction of the electroretinographic b-wave amplitude and a delayed latency, under the dark-adaptated condition. These alterations are compatible with a selective dysfunction of the rods. Antibodies raised against Trypanosoma cruzi that also interact with beta1-adrenergic receptor blocked light stimulation of cGMP-phosphodiesterase in bovine rod membranes. The specificity from the antibody-rhodopsin interaction was confirmed by Western blot analysis and antigenic competition experiments. Our results suggest an immunomediated rhodopsin blockade. T. cruzi infection probably induces an autoimmune response against rhodopsin in the chronic phase of Chagas' disease through a molecular mimicry mechanism similar to that described previously on cardiac human beta1-adrenergic and M2-cholinergic receptors, all related to the same subfamily of G-protein-coupled receptors.
Alfa-enolasa: a novel autoantigen in patients with premature ovarian failure
Sundblad, Victoria; Bussmann, Leonardo Edmundo; Chiauzzi, Violeta Alicia; Pancholy, Vijay; Charreau, Eduardo Hernan
Although controversial, the presence of circulating antiovarian antibodies (AOA) may be considered a marker of autoimmune premature ovarian failure (POF). The purpose of the present work was to evaluate the presence of AOA in POF patients, and to identify a possible autoantigen in order to develop a reliable diagnostic tool that might help to determine the real prevalence of autoimmune POF.
Metodología para determinar el potencial solar de entornos de baja densidad del área metropolitana de Mendoza
Arboit, Mariela Edith; Diblasi, Angela Magdalena; Mesa, Nestor Alejandro; de Rosa, Carlos
El presente estudio intenta aportar conocimientos y metodologías para evaluar el acceso al recurso solar del parque edilicio urbano existente, reconociendo su complejidad y definiendo con precisión las variables significativas que definen la utilización del recurso, para los usos de calefacción de espacios (muros al norte) y calentamiento de agua para uso doméstico (techos horizontales y proyección horizontal de techos con pendiente). El objetivo del mismo es aplicar un modelo estadístico de regresión lineal múltiple que permita estudiar la correlación existente entre el potencial solar del parque edilicio urbano actual (variable respuesta), y un conjunto de variables explicativas, urbanas y edilicias: forma y orientación de las manzanas, ancho de los cañones urbanos, incidencia del arbolado, morfología edilicia, áreas de parcelas, ocupación del suelo y densidad edilicia. Se propone desarrollar una metodología que permita cuantificar el potencial de la edilicia del Área Metropolitana de Mendoza (AMM), y elaborar lineamientos de diseño apropiados para formular e implementar una legislación que establezca rangos de valores para cada variable significativa, tendiente al aprovechamiento pleno del recurso solar en la ciudad, y por lo tanto al desarrollo ambiental y energéticamente sustentable.; The present study aims at contributing knowledge and methodology to assess the access to the solar resource of the existing urban building stock, a knewedging its complexity and precisely defining the utilization of the resources, for the uses of space heating (north facing walls) and domestic water heating ( horizontal roofs and horizontal projection of tilted roofs). The objective of the study is to utilize a statistical multiple linear regression model that would allow to define the correlations between the solar potential of the present building stock (variable response) and a set of urban and building explanatory variables: form and orientation of city blocks, urban canyon width, urban forest incidence, building morphology, parcel dimensions, soil occupation and building density. It is expected that the results of the study will allow to quantify the solar potential of the present building stock in MMA and elaborate suitable design guidelines for the elaboration and implementation of norms that would establish value ranges for each significant variable, aiming at the maximum utilization of the solar resource in the city, as a significant contribution to its environmental and energy sustainable development
Comparación de métodos de lisis y extracción de ADN de trofozoiteos de Giardia lamblia; Comparison of lysis methods and DNA extraction of Giardia lamblia trophozoites
Molina, Nora Beatriz; Polverino, Daniela; Minvielle, Marta Cecilia; Apezteguía, María; Aguilar, Orlando Mario; Basualdo, Juan A.
The efficiency of lysis procedures and DNA purification treatments of Giardia lamblia trophozoites were evaluated regarding the breaking-up efficiency, quantity and pureness of DNA, processing time and costs. Five lysis methods (distilled water and heating; distilled water, heating and proteinase K; buffer D Lysis; buffer E lysis, and commercial kit), and three DNA purification methods (phenol:chloroform:isoamilic, Chelex 100 and commercial kit) were tested. The obtained data were statistically analyzed. The buffer E lysis and Chelex combination was simple and economic method which produced high DNA performance with low pureness. Commercial kit was simple and expensive method which generated low yields of DNA with appropriate purity level for molecular analysis.; Se evaluó la eficiencia de procedimientos de lisis y tratamientos de extracción de ADN de trofozoítos de Giardia lamblia respecto a la eficiencia de ruptura, cantidad y pureza de ADN, además de los tiempos de procesamiento y costos. Se testearon cinco métodos de lisis (agua destilada y calor; agua destilada, calor y proteinasa K; buffer de lisis D; buffer de lisis E y un kit comercial) y tres métodos de purificación de ADN (fenol:cloroformo: isoamílico; Chelex 100 y un kit comercial). Los datos obtenidos se analizaron estadísticamente. La combinación de buffer de lisis E y Chelex fue un método simple y económico, que produjo alto rendimiento de ADN con baja pureza. Ella técnica comercial fue un método simple, más costoso que produjo bajas cantidades de ADN con un nivel de pureza apropiado para estudios moleculares.
The equilibrium limit of the Casati-Prosen model
Castagnino, Mario Alberto G. J.
An alternative explanation of the decoherence in the Casati–Prosen model is presented. It is based on the self-induced decoherence formalism extended to non-integrable systems.
Description of Maunder-like events from a stochastic Alpha–Omega model
Gomez, Daniel Osvaldo; Mininni, Pablo Daniel
One of the most impressive solar phenomena is its magnetic activity cycle. The number of sunspots observed in the solar surface varies with a period of approximately 11 years. Superimposed to this cyclic behavior, there are sporadic events such as the Maunder minimum, during which very few sunspots were detected. In the present work, an Alpha–Omega dynamo model is proposed to study these phenomena. We use velocity profiles of the solar interior obtained from helioseismology, which include differential rotation (the X-effect), a meridional flow and the turbulent velocity field of the convective region (the a-effect). By simulating the helicoidal and disordered flow of the giant cells through a stochastic component in the a coefficient, we reproduce not only the periodic behavior of the solar cycle, but also sporadic events such as the Maunder minimum. This model suggests the existence of a link between giant cell fluctuations and the irregularities observed in the solar cycle, such as north–south asymmetries and secular variations like
the Maunder minimum.
Redescription of Excirolana armata (Dana, 1853) and synonymy of Cirolana argentina Giambiagi, 1930 (Crustacea: Isopoda: Cirolanidae)
Ribetti, Virginia L.; Roccatagliata, Daniel Carlos
Excirolana armata (Dana, 1853) is redescribed on the basis of material collected from Puerto Quequén, Argentina, the type locality of Cirolana argentina Giambiagi, 1930. Based on this material, it is concluded that C. argentina is a junior synonym of E. armata. The distribution of E. armata is extended from Rio de Janeiro to Golfo San José (northern Patagonia). Excirolana armata is most similar to the Chilean species Excirolana hirsuticauda Menzies, 1962 and Excirolana monodi Carvacho, 1977; a table comparing these three species is provided. The male second pleopod and pleotelson of E. hirsuticauda are illustrated.