Ciencia y Tecnología

Precariado y Política: Emprendedurismo y juventudes mejoristas

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Precariado y Política: Emprendedurismo y juventudes mejoristas; Precariat and Politics. Entrepreneurship and youth “mejoristas”; Precariado e Política. Empreendedorismo e juventude “mejorista” Welschinger Lascano, Nicolás Sebastían; Seman, Pablo Federico En este artículo sostendremos que el triunfo del mileísmo se alimentó de una transformación sociolaboral que ocurrió en los sectores medios y populares argentinos que vivieron el estancamiento económico de los últimos diez años junto con la crisis de la pandemia, las restricciones de la cuarentena, la reconfiguración del mundo laboral y la espiralización de la inflación. A la victoria de Milei le precede un cambio socio laboral y cultural, un cambio en la sociedad que encontró un actor capaz de performatizar los reclamos de una mayoría que creció a espaldas de y contra la representación política tradicional: la emergencia de una sensibilidad popular que llamamos “mejorismo”. Nuestra tesis es que una de las sedes cruciales de la sensibilidad “mejorista” son las juventudes con trabajos informales y que el triunfo electoral de Milei y la consolidación inesperada de su gobierno se deben en gran parte a que el “mejorismo”, que es parte del apuntalamiento electoral de Milei, es también el sostén del gobierno libertario. Sobre la base de un trabajo etnográfico, a lo largo del artículo describimos el “mejorismo” como la sensibilidad popular emergente que afirma la autonomía individual de los sujetos frente al Estado y la política, que cree que el mejor desempeño social posible se logra a través del esfuerzo personal. El artículo explora la relación entre la producción de la subjetividad mejorista y los nuevos liderazgos políticos que dieron lugar a la afinidad ideológica y política entre importantes sectores de las juventudes con trabajos informales y el programa libertario.; In this article we will argue that the triumph of Mileism was fueled by a socio-labor transformation that occurred in the Argentine middle and popular sectors that experienced the economic stagnation of the last ten years along with the pandemic crisis, quarantine restrictions, the reconfiguration of the labor world and the spiraling inflation. Milei's victory was preceded by a socio-labor and cultural change, a change in society that found an actor capable of performing the claims of a majority that grew up behind and against traditional political representation: the emergence of a popular sensibility that we call "mejorismo." Our thesis is that one of the crucial sites of the "mejorista" sensibility is the youth with informal jobs and that Milei's electoral victory and the unexpected consolidation of his government are largely due to the fact that "mejorismo," which is part of Milei's electoral support, is also the support of the libertarian government. Based on ethnographic work, throughout the article we describe “mejorismo” as the emerging popular sensibility that affirms the individual autonomy of subjects in the face of the State and politics, which believes that the best possible social performance is achieved through personal effort. The article explores the relationship between the production of “betterism” subjectivity and the new political leaderships that gave rise to the ideological and political affinity between important sectors of youth with informal jobs and the libertarian program.; Neste artigo argumentaremos que o triunfo do mileísmo foi nutrido por uma transformação sócio- trabalhista ocorrida nos setores médios e populares argentinos que vivenciaram a estagnação econômica dos últimos dez anos juntamente com a crise pandêmica, as restrições de quarentena, a reconfiguração do o mundo do trabalho e a espiral da inflação. A vitória de Milei é precedida por uma mudança sócio- laboral e cultural, uma mudança na sociedade que encontrou um ator capaz de cumprir as demandas de uma maioria que cresceu atrás e contra a representação política tradicional: o surgimento de uma sensibilidade popular que chamamos de “mejorismo”. ” Nossa tese é que um dos assentos cruciais da sensibilidade “melhorista” são os jovens com empregos informais e que a vitória eleitoral de Milei e a consolidação inesperada de seu governo se devem em grande parte ao fato de que o “mejorismo”, que faz parte do sistema eleitoral de Milei, apoio, é também o apoio do governo libertário. Com base no trabalho etnográfico, ao longo do artigo descrevemos o “mejorismo” como a sensibilidade popular emergente que afirma a autonomia individual dos sujeitos frente ao Estado e à política, que acredita que o melhor desempenho social possível é alcançado através do esforço pessoal. O artigo explora a relação entre a produção de subjetividade melhorista e as novas lideranças políticas que deram origem à afinidade ideológica e política entre importantes setores da juventude com empregos informais e o programa libertário.

Cara y ceca del hábitat popular en el Conurbano Bonaerense: Entre la inquilinización y la institucionalización

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Cara y ceca del hábitat popular en el Conurbano Bonaerense: Entre la inquilinización y la institucionalización; Heads and tails of the popular habitat in the Conurbano Bonaerense: Between tenancy and institutionalization Vio, Marcela Laura El artículo tiene por objetivo actualizar la comprensión de la cuestión que atañe al hábitat popular del aglomerado más poblado y complejo de la jerarquía urbana argentina: el Conurbano Bonaerense. El interés principal está puesto en el análisis de los procesos recientes que definen condiciones de vida de los hogares populares que lo habitan. De la investigación territorial emergen dos fenómenos específicos de los años recientes. Uno observable de manera directa con herramientas metodológicas de investigación territorial y el segundo requiere otras mediaciones para la comprensión de las implicancias que tiene para esos hogares. El primero de estos procesos es el del crecimiento de la inquilinización y el segundo la institucionalización del hábitat popular a partir de la creación del Registro Nacional de Barrios Populares (RENABAP). El análisis de ambos fenómenos implica capturar las complejidades propias de los procesos sociales, ya que mientras que el primero conlleva un empeoramiento de las condiciones de vida, el segundo significa una forma de reconocimiento de un modo de habitar de las clases populares que ha sido analizado como provisorio muchas veces, pero que ha demostrado su condición de permanente. Metodológicamente el artículo presenta datos primarios -resultantes de un relevamiento territorial realizado en el barrio Villa Jardín (Lanús) en el año 2023 que aplicó herramientas cuantitativas y cualitativas- que complementa con datos de fuentes secundarias. Conceptualmente recorre cada uno de los procesos desde una perspectiva teórica que articula categorías del campo de los estudios del hábitat y de la economía popular. Se espera que los resultados de la investigación que aquí se presentan contribuyan a la formulación de preguntas y a la apertura de nuevos prismas que permitan profundizar el análisis de los fenómenos que constituyen el objeto de la misma.; The article aims to update the understanding of the issue that concerns the popular habitat of the most populated and complex agglomerate of the Argentine urban hierarchy: the Buenos Aires suburbs. The main interest is placed on the analysis of recent processes that define living conditions of the popular households that inhabit it. Two specific phenomena of recent years emerge from territorial research. One is directly observable with methodological tools of territorial research and the second requires other mediations to understand the implications it has for those households. The first of these processes is the growth of tenancy and the second the institutionalization of the popular habitat from the creation of the National Registry of Popular Neighborhoods (RENABAP). The analysis of both phenomena implies capturing the complexities of social processes, since while the first entails a worsening of living conditions, the second means a form of recognition of a way of living of the popular classes that has been analyzed. as temporary many times, but which has demonstrated its permanent status. Methodologically, the article presents primary data –resulting from a territorial survey carried out in the Villa Jardin neighborhood (Lanús) in 2023 that applied quantitative and qualitative tools– which it complements with data from secondary sources. Conceptually, it covers each of the processes from a theoretical perspective that articulates categories from the field of habitat studies and popular economy. It is expected that the results of the research presented here will contribute to the formulation of questions and the opening of new prisms that allow for a deeper analysis of the phenomena that constitute the object of the research.

A tetrasporic Octospora (Pyronemataceae, Pezizales) in South America

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A tetrasporic Octospora (Pyronemataceae, Pezizales) in South America; Octospora tetrasporado (Pyronemataceae, Pezizales) en Sudamérica Suarez, Guillermo Martin Octospora gemmicola var. tetraspora (Pyronemataceae), a species of bryophilous ascomycete, is recorded for the first time in South America from Argentina. This taxon is characterized by its parasitism on the propaguliferous moss Bryum klinggraeffii and the presence of tetrasporic asci. Macroscopic and microscopic features and ecological aspects of Octospora gemmicola var. tetraspora are discussed. Furthermore, pictures regarding conditions of the Argentinian occurrences, microscopic characters including spores, and infection structure are provided. Other related Octospora species with four-spored asci are discussed with the Argentinian collection, including a comparative illustration.; Octospora gemmicola var. tetraspora (Pyronemataceae), un ascomiceto briófilo, se registra para Sudamérica, en Argentina. Este espécimen se caracteriza por su parasitismo sobre el musgo propagulífero Bryum klinggraeffii y por la presencia de ascas tetrasporadas. Se discuten las características macroscópicas, microscópicas y aspectos ecológicos de Octospora gemmicola var. tetraspora. Además, se proporcionan imágenes que documentan las condiciones de las ocurrencias argentinas, así como los caracteres microscópicos, incluidas las esporas y las estructuras de infección. Otras especies de Octospora de ascas con cuatro esporas se relacionan con la colección de Argentina, incluyendo una ilustración comparativa.

Novedades del género Sematophyllum (Sematophyllaceae, Bryophyta) en Uruguay

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Novedades del género Sematophyllum (Sematophyllaceae, Bryophyta) en Uruguay; Novelties of the genus Sematophyllum (Sematophyllaceae, Bryophyta) in Uruguay Colotti, María T.; Suarez, Guillermo Martin El presente estudio documenta novedades del género Sematophyllum para la República Oriental del Uruguay. Cuatro especies: S. cuspidiferum, S. galipense, S. lithophilum y S. subsimplex, se citan como nuevos registros para la brioflora del país y se amplía el área de distribución de S. subpinnatum. Se incluye la descripción de los taxa, su ilustración, comentarios y observaciones taxonómicas de cada una de las especies aquí tratadas. Además, se presenta una clave de identificación.; This study documents new records of the genus Sematophyllum in Uruguay. Four species, S. cuspidiferum, S. galipense, S. lithophilum, and S. subsimplex, are newly reported for the bryophyte flora of Uruguay, while the known distribution of S. subpinnatum is expanded. The study includes descriptions, illustrations, taxonomic notes, and additional observations for each species. An identification key is also provided.

Pre-Existing Anti-Inflammatory Immune Conditions Influence Early Antibody Avidity and Isotype Profile Following Comirnaty® Vaccination in Mice

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Pre-Existing Anti-Inflammatory Immune Conditions Influence Early Antibody Avidity and Isotype Profile Following Comirnaty® Vaccination in Mice Castillo, Mariángeles; Miraglia, Maria Cruz; Mansilla, Florencia Celeste; Randazzo, Cecilia Paola; Bentancor, Leticia Verónica; Freire, Teresa; Capozzo, Alejandra Victoria Background/Objectives: Vaccine immunogenicity is often suboptimal in vulnerable populations such as the elderly, infants, and individuals in low- and middle-income countries. One contributing factor may be pre-existing immunomodulatory conditions, including helminth infections. This study investigates the impact of Fasciola hepatica (F. hepatica) derived molecules on the early humoral response to the COVID-19 mRNA vaccine Comirnaty® in a mouse model. Methods: BALB/c mice were pretreated with a F. hepatica protein extract (FH) or complete Freund’s adjuvant (CFA) prior to vaccination. Cytokine production and antibody responses were assessed at 0, 14, and 21 days post-vaccination (dpv) through serum analysis and ex vivo splenocyte stimulation with the SARS-CoV-2 receptor-binding domain (RBD) or LPS. Results: At 0 dpv, FH-treated mice showed increased serum IL-10, while CFA treatment induced IL-12. FH- but not CFA-treated splenocytes secreted IL-10 upon RBD or LPS stimulation. At 21 dpv, FH-treated mice lacked IFN-γ production but maintained IL-10 and showed elevated IL-4, consistent with a Th2-skewed profile. Although total anti-RBD IgG levels were similar between groups, FH-treated mice exhibited reduced IgG avidity and a higher IgG1/IgG2 ratio. CFA-treated mice showed delayed avidity maturation. Conclusions: Prior exposure to F. hepatica antigens can modulate the early immune response to Comirnaty®, affecting both cellular activation and antibody quality. This altered response may reflect a reduced early protective capacity of the vaccine, which might need to be considered when designing or evaluating vaccination strategies using mRNA vaccines in helminth-endemic regions.

Aprender el protagonismo: Enseñanzas de una experiencia de educación popular con niñeces

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Aprender el protagonismo: Enseñanzas de una experiencia de educación popular con niñeces; Learning protagonism: Lessons from a popular education experience with children Morales, Santiago Joaquín En nuestras sociedades adultocéntricas no se reconoce a las niñeces como sujetas sociales y políticas. Por eso resulta lógico que no se les enseñe ni a participar, ni a tener iniciativa, ni a organizarse para que sus voces sean escuchadas. No obstante, desde diferentes experiencias de organización popular en Latinoamérica se vienen desplegando prácticas pedagógico-políticas que promueven su protagonismo, en una búsqueda más amplia por disputar tanto los sentidos construidos como las estructuras institucionales que limitan el ejercicio de sus derechos. Una de esas experiencias es analizada en este artículo: la Asamblea REVELDE de Barrio Fátima (2014-2020), una organización de niñeces de un barrio popular de la Ciudad de Buenos Aires en Argentina. Enmarcado en una “sistematización de experiencia”, propuesta investigativa crítica construida en el encuentro entre la academia y la educación popular, este artículo busca analizar aquello que las niñeces identifican como aprendizajes de su proceso de organización. Desde las voces y perspectivas de las niñeces, el estudio ofrece una posible definición de la noción de protagonismo en cuatro dimensiones: poder subjetivo, escucha y respeto mutuo, derechos y responsabilidad, y organización.; In our adultcentric societies, children are not recognized as social and political subjects. It is therefore logical that they are neither taught to participate, nor to take the initiative, nor to organize themselves so that their voices are heard. However, from different experiences of popular organization in Latin America, pedagogical-political practices are being deployed that promote the protagonism of children, in a broader search to dispute both the constructed meanings and the institutional structures that limit the exercise of their rights. One such experience is analyzed in this article: the REVELDE Assembly of Barrio Fatima (2014-2020), an organization of children from a popular neighborhood of the City of Buenos Aires in Argentina. Framed in an “experience systematization”, a critical research proposal built in the encounter between academia and popular education, this article seeks to analyze what the children identify as lessons learned from their organization process. From the voices and perspectives of the children, the study offers a possible definition of the notion of protagonism in four dimensions: subjective power, listening and mutual respect, rights and responsibility, and organization.

Modified natural mineral with a biogenic compound to control microbial growth in waterborne paint

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Modified natural mineral with a biogenic compound to control microbial growth in waterborne paint Barberia Roque, Leyanet; Lopez, Guillermo Pablo; Gámez Espinosa, Erasmo Junior; Igal, Katerine; Fernandez, Mariela Alejandra; Deyá, Cecilia; Bellotti, Natalia Hygienic paints are designed to control microbial growth by imparting antimicrobial activity both in-film and incan. Biogenic compounds like terpenes in essential oils (EOs) have potential antimicrobial properties. Additionally, modified montmorillonites (Mt) show promise as nanoscale carriers for these compounds. This research aimed to obtain a functionalized antimicrobial montmorillonite hybrid to be applied in the formulation of bioactive paints. The biogenic compounds evaluated were the essential oils of white thyme and mint, to be applied for the first time in hygienic coatings. A soybean derivative was used as an organic modifier of the clay mineral. The synthesized hybrids were characterized by Fourier-Transform Infrared (FTIR) spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and energy dispersive spectrometer (EDS). Bioassays were carried out against fungal strains including Cladosporium cladosporioides, Chaetomium globosum, and Aspergillus versicolor, as well as bacterial strains such as Staphylococcus aureus and Escherichia coli. White thyme was the EO with the higher antimicrobial activity. Added to this, white thyme oil managed to impart its antimicrobial activity to the synthesized hybrid. The formulated paints with 0.75 concentration of pigment per volume (PVC) efficiently prevented in-can pollution.

Low-cost algorithms for clinical notes phenotype classification to enhance epidemiological surveillance: A case study

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Low-cost algorithms for clinical notes phenotype classification to enhance epidemiological surveillance: A case study Petri, Javier; Barcena Barbeira, Pilar; Pesce, Martina; Xhardez, Verónica; Laje, Rodrigo; Cotik, Viviana Erica Objective:Our study aims to enhance epidemic intelligence through event-based surveillance in an emerging pandemic context. We classified electronic health records (EHRs) from La Rioja, Argentina, focusing on predicting COVID-19-related categories in a scenario with limited disease knowledge, evolving symptoms, non-standardized coding practices, and restricted training data due to privacy issues.Methods:Using natural language processing techniques, we developed rapid, cost-effective methods suitable for implementation with limited resources. We annotated a corpus for training and testing classification models, ranging from simple logistic regression to more complex fine-tuned transformers.Results:The transformer-based, Spanish-adapted models BETO Clínico and RoBERTa Clínico, further pre-trained with an unannotated portion of our corpus, were the best-performing models (F1= 88.13% and 87.01%). A simple logistic regression (LR) model ranked third (F1=85.09%), outperforming more complex models like XGBoost and BiLSTM. Data classified as COVID-confirmed using LR and BETO Clínico exhibit stronger time-series Pearson correlation with official COVID-19 case counts from the National Health Surveillance System (SNVS 2.0) in La Rioja province compared to the correlations observed between the International Code of Diseases (ICD-10) codes and the SNVS 2.0 data (0.840, 0.873, and 0.663, p-values < 3x10^-7). Both models have a good Pearson correlation with ICD-10 codes assigned to the clinical notes for confirmed (0.940 and 0.902) and for suspected cases (0.960 and 0.954), p-values < 3x10^-18.Conclusion:This study shows that simple, resource-efficient methods can achieve results comparable to complex approaches. BETO Clínico and LR strongly correlate with official data, revealing uncoded confirmed cases at the pandemic’s onset. Our results suggest that annotating a smaller set of EHRs and training a simple model may be more cost-effective than manual coding. This points to potentially efficient strategies in public health emergencies, particularly in resource-limited settings, and provides valuable insights for future epidemic response efforts.

Psychometric properties analysis of the Motivational Self-Regulation Strategies Questionnaire

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Psychometric properties analysis of the Motivational Self-Regulation Strategies Questionnaire; Análisis de las propiedades psicométricas del Cuestionario de Estrategias de Autorregulación Motivacional; Análise das propriedades psicométricas do Questionário de Estratégias de Autorregulação Motivacional Freiberg Hoffmann, Agustín; Motta, Florencia Anabel; Tisocco, Franco; Sánchez Rosas, Javier Motivational self-regulation allows students tosustain and/or improve their motivation to achieve their goals. Thisself-regulation variant is related to variables such as academic performance,classroom climate, and academic procrastination, among others. The MotivationalSelf-Regulation Strategies Questionnaire (MRSQ) operationalized the construct. Thequestionnaire was adapted in Córdoba (Argentina), dividing the dimensions ofgoal regulation according to the strategies employed ­— whether by approximationor avoidance. The present research proposes to analyze new evidence of thevalidity and reliability of the MRSQ. A total of 412 university students fromBuenos Aires (Argentina) participated in the study. The analysis of theinternal structure of the instrument using confirmatory factor analysis (CFA)and exploratory structural equation modeling (ESEM) verified a better fit forthe 8-factor model. Further, a measurement invariance analysis between samplesof students from Buenos Aires and Córdoba verified the metric equivalence ofthe MRSQ. The internal consistency of the dimensions was adequate (> .70).Next, the concurrent validity test yielded positive and significantcorrelations with learning approaches and negative correlations with academicprocrastination. Statistical norms were also computed. This work provides newevidence on the psychometric properties of the MRSQ and norms that enable itsuse and interpretation within applied settings.; La autorregulación motivacional permite a los estudiantes sostener o mejorar su motivación para alcanzar sus metas. Esta autorregulación se relaciona con variables relevantes como el rendimiento académico, el clima de clase y la procastinación académica, entre otras. El Cuestionario de Estrategias de Autorregulación Motivacional (CEAM) operacionaliza el constructo y fue adaptado en Córdoba (Argentina), dividiendo las dimensiones de regulación de metas según las estrategias empleadas sean por aproximación o evitación. Esta investigación propone analizar nuevas evidencias de validez y confiabilidad del CEAM. Participaron 412 estudiantes universitarios de Buenos Aires (Argentina). El análisis de la estructura interna del instrumento mediante análisis factorial confirmatorio (AFC) y el análisis de ecuaciones estructurales exploratorio (ESEM) verificaron el mejor ajuste para el modelo de ocho factores. Luego, un análisis de invarianza factorial entre muestras de estudiantes de Buenos Aires y Córdoba verificó la equivalencia métrica del CEAM. La consistencia interna de las dimensiones fue adecuada (> .70). Seguidamente, el examinen de validez concurrente arrojó correlaciones positivas y significativas con los enfoques de aprendizaje, y negativas con la procastinación académica. También se estimaron normas estadísticas. Este trabajo proporciona nuevas evidencias sobre las propiedades psicométricas del CEAM y baremos que posibilitan su uso e interpretación dentro del campo de aplicación.; A autorregulação motivacional permite aos estudantes manterem e/ou melhorarem sua motivação para alcançar suas metas. Essa autorregulação está relacionada com variáveis relevantes, como o desempenho acadêmico, o clima de sala de aula e a procrastinação acadêmica, entre outras. O Questionário de Estratégias de Autorregulação Motivacional (QEAM) operacionaliza o construto e foi adaptado em Córdoba (Argentina), dividindo as dimensões da regulação de metas de acordo com as estratégias empregadas, sejam elas por aproximação ou evitação. Esta pesquisa propõe analisar novas evidências de validade e confiabilidade do QEAM. Participaram 412 estudantes universitários de Buenos Aires (Argentina). A análise da estrutura interna do instrumento, por meio da análise fatorial confirmatória (AFC), e da análise exploratória de equações estruturais (ESEM) verificou o melhor ajuste para o modelo de oito fatores. Em seguida, uma análise de invariância fatorial entre amostras de estudantes de Buenos Aires e Córdoba verificou a equivalência métrica do QEAM. A consistência interna das dimensões foi adequada (> 0,70). Em seguida, o teste de validade concorrente revelou correlações positivas e significativas com as abordagens de aprendizagem e correlações negativas com a procrastinação acadêmica. As normas estatísticas também foram estimadas. Este trabalho fornece novas evidências sobre as propriedades psicométricas do QEAM e escalas que permitem seu uso e interpretação no campo de aplicação.

Tall salt marshes play a crucial role in the long-term geomorphic evolution of the Jiuduansha wetland, Yangtze estuary, China

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Tall salt marshes play a crucial role in the long-term geomorphic evolution of the Jiuduansha wetland, Yangtze estuary, China Ma, Hao; Wang, Lihua; Pratolongo, Paula Daniela; Wu, Guoxiang; Shi, Benwei Salt marshes play a pivotal role in shaping coastal wetlands by influencing hydrodynamics and sediment transport, a topic that has garnered increasing attention in recent studies. However, the specific roles of different vegetation types in driving geomorphic evolution remain unclear. This study aims to assess the impact of varying salt marsh vegetation on the long-term geomorphic evolution of coastal wetlands. Using 1449 satellite images spanning 39 years (1984–2023) from the Google Earth Engine data archive, we investigated how different salt marsh types influences geomorphic changes on Jiuduansha Island, the largest uninhabited island in the Yangtze Estuary, China. Our analysis focused on the long-term salt marsh expansion and geomorphic evolution of Jiuduansha. The results revealed that the total area of Jiuduansha, as well as the extent of tall salt marshes, has increased significantly over the past decade. Notably, tall salt marshes exert a profound influence on geomorphic evolution. Specifically, in the accretionary sections of Jiuduansha Island, the natural expansion of tall salt marshes (Spartina alterniflora and Phragmites australis, with mean heights of 1.8 m and 2.5 m, respectively) drives seaward progradation. Conversely, in erosional sections, these tall salt marshes play a crucial role in mitigating further shoreline erosion. This study underscores the significant role of tall salt marshes in the long-term geomorphic evolution of coastal wetlands, offering valuable insights into the dynamics of wetland ecosystems and their resilience to environmental changes.

Modeling and solving an integrated periodic vehicle routing and capacitated facility location problem in the context of solid waste collection

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Modeling and solving an integrated periodic vehicle routing and capacitated facility location problem in the context of solid waste collection González, Begoña; Rossit, Diego Gabriel; Frutos, Mariano; Méndez, Máximo Few activities are as crucial in urban environments as waste management. Mismanagement of waste can cause significant economic, social, and environmental damage. However, waste management is often a complex system to manage and therefore where computational decision-support tools can play a pivotal role in assisting managers to make faster and better decisions. In this sense, this article proposes, on the one hand, a unified optimization model to address two common waste management system optimization problem: the determination of the capacity of waste bins in the collection network and the design and scheduling of collection routes. The integration of these two problems is not usual in the literature since each of them separately is already a major computational challenge. Two improved exact formulations based on mathematical programming and two metaheuristic methods are provided to solve this proposed unified optimization model. It should be noted that the metaheuristics consider a mixed chromosome representation of the solutions combining binary and integer alleles, in order to solve realistic instances of this complex problem. Different parameters of the metaheuristics considered – a Genetic Algorithm and a Simulated Annealing algorithm – have been tested to study which combination of them obtained better results in execution times on the order of that of the exact solvers. The achieved results show that the proposed metaheuristic methods perform efficient on large instances, where exact formulations are not applicable, and offer feasible, high-quality solutions in reasonable calculation times.

Spectrally distinguishing symmetric spaces I

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Spectrally distinguishing symmetric spaces I Lauret, Emilio Agustin; Rodríguez, Juan Sebastián We prove that the irreducible symmetric space of complex structures on (resp. quaternionic structures on ) is spectrally unique within a 2-parameter (resp. 3-parameter) family of homogeneous metrics on the underlying differentiable manifold. Such families are strong candidates to contain all homogeneous metrics admitted on the corresponding manifolds. The main tool in the proof is an explicit expression for the smallest positive eigenvalue of the Laplace-Beltrami operator associated to each homogeneous metric involved. As a second consequence of this expression, we prove that any non-symmetric Einstein metric in the homogeneous families mentioned above is -unstable.

Bridging Sectors and Disciplines to Gain a Critical Understanding of the Eco-Social Determinants of Health Inequities: The ESDHI-EU Conference

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Bridging Sectors and Disciplines to Gain a Critical Understanding of the Eco-Social Determinants of Health Inequities: The ESDHI-EU Conference Morrison, Joana; Tumas, Natalia; Moreno Mattar, Ornella; Gutiérrez Zamora Navarro, Mariana; Pericas, Juan M.; Martínez Herrera, Eliana; Cash-Gibson, Lucinda; Caroz Armayones, Josep Maria; Ruisoto, Pablo; Zografos, Christos; Rodríguez Labajos, Beatriz; Vergés Vega, Paula; Londoño, Ángela; Bautista, Marya; Karaguesian, Claire; Nuñez, Daniel; Muntané, Ferràn; Jiménez, Humberto; Vivas, Laila; Velázquez, Linda; Hsu, Po-Yen; Muntaner, Carles; Benach, Joan; Ribbons, Aeve The current eco-social crisis is driven by an unsustainable socioeconomic model based on continued economic growth that exceeds planetary limits. Groups experiencing disadvantages are being disproportionately affected, further deepening global, regional, and local health inequities. Understanding the simultaneous ecological and social crises through a comprehensiveapproach across disciplines and sectors—including citizen participation—is essential for driving transformative change and paradigm shifts. Achieving genuine ecological sustainability, social justice, and health equity is critical for transitioning towards a new social-ecological paradigm in research and policy. This requires transformative research and policymaking in key areas—eco-social crisis; democracy, social inclusion and participation; geopolitics; and equitable, sustainable cities—all of which represent pressing challenges within this global crisis, and serve as thematic axes for the European conference Rethinking the Eco-Social Determinants of Health Inequities through the Transdisciplinary and Intersectoral Lens (ESDHI-EU), which will be held inBarcelona, Spain, on May 22–23, 2025, and will explore the root causes of health inequities from a transdisciplinary, intersectoral, and transnational perspective.

Ajuste libertario, crisis y estabilización: Efectos sobre la dinámica de la pobreza y la desigualdad social

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Ajuste libertario, crisis y estabilización: Efectos sobre la dinámica de la pobreza y la desigualdad social Salvia, Hector Agustin; Vera, Julieta; Bonfiglio, Juan José; Giannecchini, Alejo Este artículo analiza el empobrecimiento de la sociedad argentina entre 2022 y 2024, con énfasis en los efectos sociales de las políticas de ajuste implementadas por el gobierno libertario de Javier Milei. A partir de la Encuesta de la Deuda Social Argentina (EDSA-ODSA-UCA), se examina la evolución de la pobreza combinando la medición tradicional por ingresos con indicadores directos de privación económica. El estudio relativiza la medición oficial de la pobreza, ya que no considera los cambios en la estructura del gasto de los hogares. Si bien se analiza la evolución de las tasas de indigencia y pobreza por ingresos, el estudio amplía el enfoque mediante la inclusión de otros indicadores directos de necesidades básicas de los hogares, como la seguridad alimentaria y el acceso a la salud. Además, incorpora un análisis longitudinal sobre la probabilidad de entrar, salir o permanecer en la pobreza durante el período 2022-2024. Los resultados evidencian que el ajuste ha profundizado las privaciones económicas y la desigualdad, afectando especialmente a los sectores más vulnerables, lo que subraya la necesidad de mediciones más integrales.; This article analyzes the impoverishment of Argentine society between 2022 and 2024, focusing on the social effects of the adjustment policies implemented by the libertarian government of Javier Milei. Using data from the Encuesta de la Deuda Social Argentina (EDSA-ODSA-UCA), it examines the evolution of poverty by combining traditional incomebased measurement with direct indicators of economic deprivation. The study challenges the official poverty measurement, as it does not account for changes in household expenditure structures. While the analysis includes the evolution of indigence and incomebased poverty rates, it expands the scope by incorporating additional direct indicators of basic household needs, such as food security and access to healthcare. Furthermore, it integrates a longitudinal analysis of the likelihood of entering, exiting, or remaining in poverty during the 2022-2024 period. The results show that the adjustment policies have deepened economic deprivation and inequality, disproportionately affecting the most vulnerable sectors. These findings underscore the need for more comprehensive poverty measurement approaches.

Assessment of encapsulation of digestive enzymes recovered from South Atlantic fish wastes for potential biotechnological applications

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Assessment of encapsulation of digestive enzymes recovered from South Atlantic fish wastes for potential biotechnological applications Friedman, Ivana Soledad; Fernandez Gimenez, Analia Veronica; Alarcón López, Francisco Javier; Vizcaíno, Antonio Jesús Fish viscera represent an abundant and cost-effective source of digestive enzymes, particularly proteinases, which can be readily extracted and employed as bioactive components in various industrial processes to obtain value-added products. However, proteinases are sensitive to environmental factors. A successful method for maintaining their enzymatic activity is encapsulation. The aim of this study was to evaluate the encapsulation efficiency of alkaline and acid proteinases derived from wastes of the commercial fish species Merluccius hubbsi and Percophis brasiliensis from the Southwest Atlantic Ocean, and to determine the stability of their enzymatic activity under different storage conditions (room temperature and 4ºC). In addition, the effectiveness of the encapsulated proteinases using an in vitro digestion simulation assay was assessed. The results indicated that P. brasiliensis proteinases immobilized in fresh microcapsules and stored at 4°C remained stable for 60 days. Alkaline proteinases stored in freeze-dried microcapsules from both species, and fresh microcapsules from P. brasiliensis, retained their activity at both storage temperatures for 60 days. Aspartic proteinases from both species, encapsulated in freeze-dried capsules and stored at 4°C, maintained catalytic activity. In vitro enzymatic hydrolysis assays confirmed that casein is hydrolyzed after 60 min by both the encapsulated and free enzymes. In turn, the amount of free amino acids released from casein leveled off after 180 min of in vitro assay. These results evidenced that encapsulation using a combination of alginate and chitosan is a promising tool for different biotechnological applications of these fish enzymes such as elaboration of commercial detergent additives and aquafeeds.

Obvious manipulations in matching with and without contracts

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Obvious manipulations in matching with and without contracts Arribillaga, Roberto Pablo; Pepa Risma, Eliana Beatriz This paper explores many-to-one matching models, both with and without contracts, where doctors’ preferences are private and hospitals’ preferences are public and substitutable. It is known that any stable-dominating mechanism --which is either stable or individually rational and Paretodominates (from the doctors’ perspective) a stable mechanism–, is susceptible to manipulation by doctors. Our study focuses on obvious manipulations and identifies stable-dominating mechanisms that prevent them. Without contracts, we show that any stable-dominating mechanism is not obviously manipulable. However, with contracts, none of these results hold. While we demonstrate that the Doctor-Proposing Deferred Acceptance (DA) Mechanism remains not obviously manipulable, we show that the Hospital-Proposing DA Mechanism and any efficient mechanism that Pareto-dominates the Doctor-Proposing DA Mechanism become (very) obviously manipulable, in the model with contracts.

Fipronil tissue residues and withdrawal period feasibility in laying hens after extra‐label use

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Fipronil tissue residues and withdrawal period feasibility in laying hens after extra‐label use Cantón, Lucila; Berkovic, Andrea Mariela; Ceballos, Laura; Cantón, Candela; Lanusse, Carlos Edmundo; Alvarez, Luis Ignacio; Moreno Torrejon, Laura Fipronil, a broad-spectrum insecticide, is often used off-label in laying hens to control red mites. This study investigatedfipronil residue levels in hen tissues after simulating common extra-label administrations: in-feed (1 mg kg−1 twice) and transdermal (1 mg kg−1 once). Fipronil residues were quantified by HPLC-MS/MS. Both administrations resulted in quantifiableresidues in edible tissues (muscle, liver, kidney, skin, fat) and feathers for up to 60 days. Fipronil-sulfone, the primary metabolite, was the dominant residue in tissues. Fat accumulated the highest concentrations. In-feed administration led to higheroverall residues in edible tissues, while transdermal application resulted in higher concentrations in feathers. Calculated withdrawal periods, based on established MRLs, ranged from 36 days (muscle, transdermal) to 131 days (fat, transdermal). Theselong withdrawal periods render both administration routes impractical for poultry production. The study highlights the riskof fipronil residues in poultry products and suggests feather/fecal sampling for monitoring illicit use.

Isospectral CR Manifolds with Respect to the Kohn Laplacian

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Isospectral CR Manifolds with Respect to the Kohn Laplacian Gutierrez, Gerson; Lauret, Emilio Agustin; Rossetti, Juan Pablo We prove that the spectrum of the Kohn Laplacian does not determine the equivalence classes of CR manifolds. We construct pairs of odd-dimensional elliptic manifolds that are not equivalent as CR manifolds but whose Kohn Laplacians have the same spectrum. These manifolds are endowed with the CR structures inherited from the canonical CR structure on the sphere of the same dimension.We provide three different constructions among lens spaces and an additional one among elliptic manifolds with non-cyclic fundamental groups.

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