Presence of human Papilloma Virus in a series of breast carcinoma from Argentina Pereira Suárez, Ana Laura; Lorenzetti, Mario Alejandro; González Lucano, René; Cohen, Melina; Gass, Hugo; Martínez Vázquez, Paula; González, Pedro Horacio; Preciado, María Victoria; Chabay, Paola Andrea Background: The etiology and the molecular mechanisms related to breast carcinogenesis remain poorly understood. Some recent reports have examined the role of Human Papillomavirus (HPV) in this disease. The purpose of this study was to determine the prevalence of HPV in breast cancer. Methods: Sixty one fresh frozen breast cancers samples were analyzed. Samples were tested for HPV by PCR, and products were automatically sequenced. Findings were correlated with clinical and pathological characteristics. Results: The HPV DNA prevalence in the breast cancer samples was 26% (16/61). Clinical parameters were not statistically associated with HPV presence (p>0.05 χ2 test). Sequence analysis in a subgroup of cases indicates the prevalence of low risk HPV11, followed by high risk HPV16. We found no HPV transcriptional activity. Conclusion: The present study demonstrated for the first time in Argentina the presence of HPV in a proportion of the malignant breast tissues. This finding suggests that HPV may have a biological significance in breast carcinogenesis.

Abogados/as de los niños, niñas, y adolescentes: Reflexiones desde el derecho procesal; The lawyers of children and adolescents: procedural law’s perspective Robledo, Diego En este artículo presentamos la figura del abogado del niño, niña y adolescente a la luz de la Constitución Nacional, Convención Internacional sobre Derechos del Niño, la Ley Nacional N° 26061, recomendaciones y observaciones de órganos de derechos humanos, y dos casos de jurisprudencia de la Corte Suprema de Justicia de la Nación. Reflexionamos sobre los derechos del niño, niña y adolescente en su faz procesal, con el derecho a ser escuchados, el interés superior del niño y el debido proceso legal, ello a la luz de las conclusiones del V Congreso Mundial sobre Derechos de la Niñez y Adolescencia (2012)del cual participamos.; In this article we present the lawyer of children under the National Constitution, Convention on the Rights of the Child, Act N°26061, recommendations and observations of International Bodiescreated for the protection of Human Rights, and two law-cases of the National High Court of Justice of Republic Argentina. We reflex about children’s rights in the judicial-procedural reality, with the right tobe heard, the superior interest of child and due process of law. Moreover, it is in light of the V Mundial Conference about Children and Adolescent’s Rights (2012).

El agotamiento del Bioma y sus consecuencias; Consequences of Biome Depletion Salvucci, Emiliano Jesus El microbioma constituye el conjunto de microorganismos asociados a un hospedero principal. Es una parte integral del superorganismo que integran los microorganismos y el hospedero y éstos han coevolucionado desde los primeros días de la existencia de la especie humana. La modificación del microbioma, sumado a los cambios en los há- bitos sociales y alimentarios del ser humano a lo largo de su historia biológica ha llevado a la emergencia de numerosas enfermedades. La visión darwinista de la naturaleza que considera a la competencia como motor evolutivo y el reduccionismo como enfoque, impiden un acertado abordaje del estudio evolutivo y la interpretación de la naturaleza. Enfoques holísticos, desprendidos de conceptos estáticos y dogmáticos, permiten un abordaje más certero, novedoso y en contacto con los hechos. Así, la reconstitución del microbioma surge como una terapia fundamental ante la emergencia de enfermedades causadas por la continua pérdida del mismo.; The human microbiome is an integral part of the superorganism together with their host and they have co-evolved since the early days of the existence of the human species. The modification of the microbiome as a result changes in food and social habits of human beings throughout their life history has led to the emergence of many diseases. In contrast with the darwinian view of nature of selfishness and competence, new holistic approaches are rising. Under these views, the reconstitution of the microbiome comes out as a fundamental therapy for emerging diseases related to biome depletion.

SpoIIIE mechanism of directional translocation involves target search coupled to sequence-dependent motor stimulation Cattoni, Diego Ignacio; Chara, Osvaldo; Godefroy, Cédric; Margeat, Emmanuel; Trigueros, Sonia; Milhiet, Pierre Emmanuel; Nöllmann, Marcelo SpoIIIE/FtsK are membrane‐anchored, ATP‐fuelled, directional motors responsible for chromosomal segregation in bacteria. Directionality in these motors is governed by interactions between specialized sequence‐recognition modules (SpoIIIE‐γ/FtsK‐γ) and highly skewed chromosomal sequences (SRS/KOPS). Using a new combination of ensemble and single‐molecule methods, we dissect the series of steps required for SRS localization and motor activation. First, we demonstrate that SpoIIIE/DNA association kinetics are sequence independent, with binding specificity being uniquely determined by dissociation. Next, we show by single‐molecule and modelling methods that hexameric SpoIIIE binds DNA non‐specifically and finds SRS by an ATP‐independent target search mechanism, with ensuing oligomerization and binding of SpoIIIE‐γ to SRS triggering motor stimulation. Finally, we propose a new model that provides an entirely new interpretation of previous observations for the origin of SRS/KOPS‐directed translocation by SpoIIIE/FtsK.

Mössbauer and vibrational DOS studies of diluted magnetic tin oxides and nano iron oxides Nomura, K.; Rykov, A. I.; Mudarra Navarro, Azucena Marisol; Rodriguez Torres, Claudia Elena; Errico, Leonardo Antonio; Barrero, Carmen Raquel; Yoda, Y. The magnetic properties and Mössbauer results for SnO2 doped with 57Fe are reviewed, and the values of isomer shift and quadrupole splitting are compared with the results obtained by ab initio calculations. It is concluded that the exchange interactions between oxygen defects and magnetic atoms are responsible for long range magnetic interactions of dilute Fe ions dispersed in SnO2. Fe atom precipitated clusters may be formed in highly Fe doped SnO2 samples by annealing at relatively high temperatures for several hours. The reduction of the particle size to nano-scale dimensions induces magnetization, which can be associated with oxygen defects. We have measured the nuclear inelastic scattering (NIS) spectra of Fe oxides, and 57Fe and (Co or Mn) doped SnO2 synthesized mainly by sol–gel methods and we have derived the vibration density of states (VDOS). The local phonons are sensitive to the presence of precipitated clusters.

Systemic infection induced by intranasal inoculation of Bovine herpesvirus 1.1 in pregnant and non-pregnant rabbits Valera, Alejandro Rafael; Fuentealba, Nadia Analia; Zanuzzi, Carolina Natalia; Corva, Santiago Gerardo; Pecoraro, Marcelo Ricardo; Barbeito, Claudio Gustavo; Galosi, Cecilia Monica Bovine herpesvirus (BoHV) type 1.1 (BoHV-1.1) causes repeated outbreaks of upper respiratory disease and abortion in cattle. The systemic effects of BoHV-1.1 in rabbits, using intranasal inoculation are reported. Female rabbits were divided into four groups and inoculated with the virus 10 days before mating, and at 15 or 22 days of pregnancy. Studies of the clinical signs, antibody production, virus isolation, and DNA detection as well as histological and immunohistochemical studies were carried out on lungs, kidneys, spleen, placentas, uteri and foetal tissues. All virus-inoculated animals developed respiratory clinical signs and a humoral response. BoHV-1.1 was isolated from nasal swabs and plasma rich in leukocytes, and viral DNA was detected in blood, dead foetuses and placentas. Histopathological lesions were found in the respiratory tract and some placentas and foetuses were immunohistochemically positive. Intranasal inoculation might be useful to study the systemic effects of BoHV-1.1 infection in the rabbit model.

Gregarious versus individualistic behavior in Vicsek swarms and the onset of first-order phase transitions Baglietto, Gabriel; Albano, Ezequiel Vicente; Candia, Julián Marcelo The standard Vicsek model (SVM) is a minimal non-equilibrium model of self-propelled particles that appears to capture the essential ingredients of critical flocking phenomena. In the SVM, particles tend to align with each other and form ordered flocks of collective motion; however, perturbations controlled by a noise term lead to a noisedriven continuous order–disorder phase transition. In this work, we extend the SVM by introducing a parameter α that allows particles to be individualistic instead of gregarious, i.e. to choose a direction of motion independently of their neighbors. By focusing on the small-noise regime, we show that a relatively small probability of individualistic motion (around 10%) is sufficient to drive the system from a Vicsek-like ordered phase to a disordered phase. Despite the fact that the α-extended model preserves the O(n) symmetry and the interaction range, as well as the dimensionality of the underlying SVM, this novel phase transition is found to be discontinuous (first order), an intriguing manifestation of the richness of the non-equilibrium flocking/swarming phenomenon.

Slim SUSY Arganda Carreras, Ernesto; Díaz Cruz, J. Lorenzo; Szynkman, Alejandro Andrés he new SM-like Higgs boson discovered recently at the LHC, with mass mh≃125GeV, as well as the direct LHC bounds on the mass of superpartners, which are entering into the TeV range, suggest that the minimal surviving supersymmetric extension of the SM (MSSM), should be characterized by a heavy SUSY-breaking scale. Several variants of the MSSM have been proposed to account for this result, which vary according to the accepted degree of fine-tuning. We propose an alternative scenario here, Slim SUSY, which contains sfermions with multi-TeV masses and gauginos/higgsinos near the EW scale, but it includes the heavy MSSM Higgs bosons (H0, A0, H±) near the EW scale too. We discuss first the formulation and constraints of the Slim SUSY scenario, and then identify distinctive heavy Higgs signals that could be searched at the LHC, within scenarios with the minimal number of superpartners with masses near the EW scale.

Egg parasitoids of Edessa meditabunda (Fabricius) (Pentatomidae) in lettuce crop Favetti, Bruna M.; Krinski, Diones; Butnariu, Alessandra; Loiacono, Marta Susana Egg parasitoids of Edessa meditabunda (Fabricius) (Pentatomidae) in lettuce crop. This study evaluated the occurrence of parasitoids in eggs of the stink bug, Edessa meditabunda (Fabricius, 1794) (Heteroptera, Pentatomidae) found on lettuce crop in Mato Grosso State, Brazil. Samples were collected in the vegetable garden “Cheiro Verde”, in the municipality of Tangará da Serra, in curly lettuce. A bed of lettuce was selected randomly, where the eggs of E. meditabunda were collected. Five-hundred and seventy eight eggs of E. meditabunda were collected, 86.3% of them parasitized by Telenomus podisi Ashmead, 1893 (Hymenoptera, Platygastridae), Trissolcus urichi Crawford, 1913 (Hymenoptera, Platygastridae) and Neorileya albipes Girault, 1913 (Hymenoptera, Eurytomidae), representing respectively 57.0%, 38.2% and 4.8% of the emerged individuals. This is the first record of these three species parasitizing eggs of E. meditabunda in lettuce.

Análisis de visibilidad aplicado a estructuras rocosas en la localidad La Primavera, Santa Cruz; Visibility analysis of stone structures at La Primavera locality, Santa Cruz Magnin, Lucia Angelica En el marco de estudios de uso del espacio por cazadores-recolectores en la localidad La Primavera, Macizo Central del Deseado (Santa Cruz, Argentina) se realizaron prospecciones sistemáticas que permitieron registrar más de 50 estructuras de rocas de origen antrópico. Atendiendo a la diversidad en su forma y dimensiones se realizó una clasificación inicial. Este trabajo se centra en uno de estos conjuntos definidos, dando a conocer información contextual de las estructuras y analizando mediante SIG la visibilidad desde el lugar de emplazamiento. Los patrones hallados sugieren la existencia de una conformación visual del espacio que integra a las estructuras de piedra dispersas en el paisaje.; As a part of space use studies in La Primavera locality, Central Deseado Massif (Santa Cruz, Argentina), more than 50 rock piles were registered in systematic surveys. An initial classification was done considering their shape and sizes. This article is focused in one of the defined classes. Contextual information is given and a visibility GIS analysis is performed with the location of the structures as the point of view. The emerged patterns suggest the existence of a visual organization of space that relates the stone structures scattered in the landscape.

Derechos indígenas en Argentina: territorios y propiedad comunitaria; Indigenous rights in Argentina. Territories and community property Maidana, Carolina Andrea; Ottenheimer, Ana Cristina; Gonzalez, Diana Victoria; Aragon, Griselda Laura; Tamagno, Liliana Ester En el siguiente trabajo se reflexiona sobre la reglamentación e implementación de Leyes en relación a las tierras/ territorios y la propiedad comunitaria indígena, a partir de las discusiones generadas por la presentación del anteproyecto de Reforma, Actualización y Unificación de los Códigos Civil y Comercial de la República Argentina. Para ello se presentan y analizan los ítems de este anteproyecto que involucran a los pueblos indígenas, las propuestas para reformularlos efectuadas por diferentes organizaciones y pueblos indígenas, así como los argumentos que éstos esgrimen en contra de la incorporación en el mismo, del tratamiento de la propiedad comunitaria indígena.; In this paper we examine the regulation and implementation of laws related to land/territories and indigenous community property from the discussions generated by the presentation of the preliminary draft of Reform, Update and Unification of the Civil and the Commercial Codes of the Argentine Republic. We discuss the items of this project related to indigenous peoples, the proposals made by different organizations and indigenous peoples to reformulate it, and the arguments they advanced against the incorporation of the community indigenous property in this preliminary draft.

The protention-retention asymmetry in Husserl's conception of time-consciousness; La asimetría de la protención-retención en la concepción del tiempo-consciencia de Husserl Dimitriu, Cristian In this paper I shall try to clarify Husserl's conception of time-consciousness. In particular, I try to explain what exactly the asymmetry between protention and retention consists in. I argue (i) that Rodemeyer's understanding of the protention-retention relationship, as developed, seems misleading, mainly for two reasons: first, it does not take into account that the 'now' has duration; second, she conceives the relation between protention and retention as symmetric, (ii) that the asymmetry between protention and retention could be better understood if we could not only take into account the influence that retention and affect have on protention, but also if we could take into consideration the conceptual difference between surprise and disappointment. This difference, I suggest, reveals new ways to understand the protention-retention asymmetry.; En este artículo intentaré clarificar la concepción del tiempo-consciencia que defiende Husserl. En particular, intentaré explicar en qué consiste exactamente la asimetría entre retención y protención. Argumento (i) que la explicación que ofrece Rodemeyer de la relación entre protención y la retención es errónea, básicamente por dos razones: en primer lugar, no tiene en cuenta que el 'ahora' tiene duración. En segundo lugar, asume que la relación entre protención y retención es simétrica, lo cual es falso. (ii) Que la asimetría entre protención y retención podría entenderse mejor si tomamos en cuenta no sólo la influencia que la retención y el afecto tienen sobre la protención, pero la diferencia conceptual que existe entre la sorpresa y la desilusión. Esta diferencia, sugiero, revela nuevas maneras de entender la asimetría entre protención y retención.

Percepciones de estudiantes de posgrado acerca de factores favorecedores y obstaculizadores del trabajo en grupo en entornos virtuales Chiecher, Analía Claudia Las TIC ofrecen hoy múltiples posibilidades de generar situaciones de trabajo grupal fundadas en el constructivismo. En este marco, el artículo focaliza la atención en el trabajo en pequeños grupos de alumnos, con asiento en entornos virtuales. Participaron del estudio 109 estudiantes de cursos de posgrado dictados con modalidad a distancia. Los alumnos se conformaron en 26 grupos, cada uno de los cuales contaba con un foro y una wiki grupal para atender al trabajo colaborativo que se les proponía resolver. Luego de concluido el trabajo respondieron dos cuestiones en las que se les solicitaba identificar en sí mismos cualidades, actitudes o acciones que hubieran favorecido u obstaculizado el trabajo en grupo. Los resultados presentan un sistema de categorías que clasifican una diversidad de actitudes, acciones y cualidades identificadas por los sujetos o bien como favorecedoras del trabajo en grupo o como barreras para su armónico funcionamiento. Las conclusiones destacan dos puntos. Por un lado, la importancia de que el funcionamiento de los grupos sea sostenido desde afuera, por el docente mismo. Por otro lado, se destacan algunas particularidades del trabajo grupal mediado por tecnologías.; ICTs offer many opportunities today to generate group work situations based on constructivism. The article focuses attention on the work of small groups of students in the context of virtual environments. Study participants were 109 students taught graduate courses in distance mode. Students were formed into 26 groups, each of which had a forum and a wiki. After completion of the work answered two questions in which they were asked to identify themselves qualities, attitudes or actions that would have helped or hindered the group work. The results present a system of categories that classify a variety of attitudes, actions and qualities identified by subjects as favoring either group work or as barriers to harmonious functioning. The findings highlight two points. On one hand, the importance of the operation of the groups is held from the outside by the same teaching. On the other hand, highlights some particularities technology mediated group work.

Análisis estructural y funcional de proteínas solubles que unen lípidos de intestino e hígado; Structure-function analysis of soluble lipid binding proteins from intestine and liver; Análise estrutural e funcional de proteínas solúveis que ligam lipídeos de intestino e fígado Falomir Lockhart, Lisandro Jorge; Córsico, Betina; Franchini, Gisela Raquel; de Gerónimo, Eduardo; Rodriguez Sawicki, Luciana; Bottasso Arias, Natalia María Luego de la ingesta, el epitelio del intestino delgado está encargado de asimilar grandes cantidades de nutrientes, como aminoácidos, glúcidos y ácidos grasos. Las proteínas solubles que unen lípidos cumplirían un rol determinante en este proceso, sobre todo protegiendo la integridad del tejido contra el efecto simil-detergente de los ácidos grasos provenientes de la dieta. En enterocitos se expresan dos proteínas que unen ácidos grasos de cadena larga, IFABP y LFABP, para las cuales no se conocen bien aún sus funciones específicas, o el porqué de la necesidad de dos proteínas aparentemente equivalentes. Este laboratorio se ha enfocado en el estudio comparativo de estas dos proteínas empleando distintas variantes estructurales y métodos bioquímicos, biofísicos, y de biología molecular y celular. Así, se han podido definir los determinantes moleculares de cada proteína responsables de la interacción con membranas, los mecanismos de transferencia de ligandos y los factores que modulan estas propiedades. Más recientemente, se han extendido estos ensayos a cultivos celulares donde se ha correlacionado la expresión de estas proteínas con la secreción de citoquinas, la proliferación y la diferenciación celular. El estudio de estas proteínas es de gran importancia por su potencial como blancos terapéuticos y su utilidad en el diagnóstico de injurias tisulares.; After ingestion, the epithelium of the small intestine is responsible for assimilating large amounts of nutrients such as amino acids, sugars and fatty acids. Soluble lipid binding proteins fulfill a determining role in this process, especially protecting the tissue integrity against the detergent-like effect of fatty acids from the diet. Two proteins that bind long-chain fatty acids are expressed in enterocytes, IFABP and LFABP, whose specific functions are still poorly understood, or the reason for the need of two apparently equivalent proteins. Our laboratory has focused on the comparative study of these two proteins using structural variants and biochemical, biophysical, and molecular and cellular biology approaches. Thus, the molecular determinants responsible for the interaction with membranes were defined for each protein, their ligand transfer mechanism and the factors that modulate these properties. More recently, these assays have been extended to cell culture studies which correlate the expression of these proteins with cytokine secretion, cell proliferation and differentiation. The study of these proteins is of great importance due to their potential as therapeutic targets and their usefulness in the diagnosis of tissue injury.; Após a ingestão, o epitélio do intestino delgado é responsável pela assimilação de uma grande quantidade de nutrientes, tais como aminoácidos, glicídios e ácidos graxos. As proteínas solúveis que ligam lipídeos desempenhariam um papel determinante neste processo, principalmente protegendo a integridade do tecido contra o efeito detergente dos ácidos graxos da dieta. Nos enterócitos se expressam duas proteínas que ligam ácidos graxos de cadeia longa, IFABP e LFABP; cujas funções específicas ainda não são muito conhecidas, ou não se conhece o motivo pelo qual são necessárias duas proteínas aparentemente equivalentes. Nosso laboratório tem se focado no estudo comparativo destas duas proteínas utilizando variantes estruturais e métodos bioquímicos, biofísicos, e de biologia molecular e celular. Assim, foi possível definir os determinantes moleculares de cada proteína responsáveis pela interação com membranas, os mecanismos da transferência de ligantes e os fatores que modulam essas propriedades. Mais recentemente, estendemos estes ensaios para culturas celulares, correlacionando a expressão destas proteínas com a secreção de citocinas, a proliferação e a diferenciação celular. O estudo destas proteínas é de grande importância por seu potencial como alvos terapêuticos e sua utilidade no diagnóstico de lesões teciduais.

Trilobites tremadocianos en facies de lutitas oscuras del miembro alfarcito (Formación Santa Rosita), Quebrada de Moya, Jujuy, Argentina; Tremadocian trilobites from dark shale facies of the alfarcito member (Santa Rosita Formation), Quebrada de Moya, Jujuy, Argentina Tortello, Marcelo Franco; Zeballo, Fernando Javier; Esteban, Susana Beatriz La Quebrada de Moya constituye una localidad clásica de la Formación Santa Rosita (Furongiano alto–Ordovícico Inferior bajo) en la Quebrada de Humahuaca (Sierra de Tilcara, Cordillera Oriental de Jujuy, Argentina), donde se destacan las facies de lutitas oscuras del intervalo superior del Miembro Alfarcito. De estos niveles se describe una fauna de trilobites compuesta por Leptoplastides marianus (Hoek), Parabolinella sp., Hapalopleura acantha Malanca y Brandán, y Asaphellus sp. Una calcarenita interestratificada en las limolitas contiene una asociación poco diversa de conodontes asignable a la Zona de Cordylodus angulatus (Tremadociano inferior). La edad ordovícica temprana está confirmada, además, por el registro del graptolito Rhabdinopora flabelliformis ssp. en una arenisca que subyace a los niveles estudiados. Las lutitas oscuras se acumularon por decantación durante períodos de máxima inundación, en un ambiente reductor de offshore distal. La fauna de trilobites está ampliamente dominada por L. marianus. Resulta interesante destacar que la parte superior del Miembro Alfarcito no exhibe facies oscuras en otros sectores de la Sierra de Tilcara. Las características sedimentológicas de la sección descripta, la baja diversidad de la asociación de conodontes y la escasez de trilobites agnóstidos sugieren condiciones de cierto aislamiento en este sector de la cuenca. Palabras clave. Trilobites. Ordovícico Inferior. Quebrada de Moya. Jujuy. Argentina.; The Quebrada de Moya constitutes a distinctive locality of the Santa Rosita Formation (uppermost Furongian–lowermost Ordovician) in the Quebrada de Humahuaca (Sierra de Tilcara, Cordillera Oriental of Jujuy, Argentina). The trilobites Leptoplastides marianus (Hoek), Parabolinella sp., Hapalopleura acantha Malanca and Brandán, and Asaphellus sp. are described from the dark shale facies of the upper part of the Alfarcito Member. A grainstone interstratified in the mudstones contains a low-diversity conodont assemblage of the Cordylodus angulatus Zone (lower Tremadocian). The Ordovician age of the section is confirmed, in addition, by the record of the graptolite Rhabdinopora flabelliformis ssp. in a sandstone underlying the studied levels. The dark shales accumulated by suspension fall-out during periods of maximum flooding, in a reducing, distal offshore marine environment. The trilobite fauna is largely dominated by L. marianus. The upper part of the Alfarcito Member does not show dark facies in other sectors of the Sierra de Tilcara. The sedimentologic characters of the section described, the low diversity of the conodont assemblage, and the scarcity of agnostoid trilobites may be indicative of a partial isolation of the basin.

First Record of Conifer Wood from the Cañadón Asfalto Formation (Early-Middle Jurassic), Chubut Province, Argentina; Primer registro de leño de conifera de la formación cañadón asfalto (Jurásico Temprano-Medio), provincia de Chubut, Argentina Bodnar, Josefina; Escapa, Ignacio Hernán; Cúneo, Néstor Rubén; Gnaedinger, Silvia Cristina A new fossil conifer wood —Brachyoxylon currumilii sp. nov.— is described from the Lower—Middle Jurassic of Chubut Province (Argentina). The specimens were collected at a locality where the Cañadón Asfalto Formation is exposed, in the vicinity of the Cerro Cóndor village. The studied wood is characterized by mixed pitting in radial tracheid walls (predominantly uniseriate), araucarioid cross fields, low uniseriate rays and the absence of resin canals. The use of transmitted light and epifluorescence microscopy together with SEM imaging allowed the identification of additional characters such as the presence of pitting with torus-margo and compression wood. These characters are discussed in terms of their systematic relevance. On these grounds, the systematic affinity of the studied wood is discussed and linked to the extinct conifer family Cheirolepidiaceae, one of the dominant plant groups during the Jurassic and Cretaceous in Patagonia.; Se describe una nueva especie de madera fósil de conífera, Brachyoxylon currumilii sp. nov., del Jurásico Inferior a Medio de la provincia de Chubut, Argentina. Los especímenes estudiados fueron coleccionados en una localidad donde aflora la Formación Cañadón Asfalto, en las cercanías de la aldea de Cerro Cóndor. Los troncos, estudiados, se caracterizan por el punteado radial de las traqueidas de tipo mixto, predominantemente uniseriado, campos de cruzamiento de tipo araucarioide, radios uniseriados bajos y ausencia de canales resiníferos. La observación bajo MEB y microscopio con luz transmitida y epifluorescencia permitió además la identificación de caracteres tales como la presencia de torus-margo en las punteaduras y estructuras de leño de compresión. Ambos caracteres son discutidos en relación a su relevancia sistemática. Sobre esta base, se discute la afinidad sistemática de la madera estudiada, la cual posee rasgos que la vincularían con la familia de coníferas extintas Cheirolepidiaceae, uno de los grupos de plantas dominantes durante el Jurásico y Cretácico de Patagonia.

Chicken eggshell as suitable calcium source at home Brun, Lucas Ricardo Martín; Lupo, Maela; Delorenzi, Damián; Di Loreto, Verónica Elina; Rigalli, Alfredo Aim: Taken into consideration that the deficiency of calcium (Ca) in the diet is a common problem, the aim of this work was to study the chicken eggshell as Ca source at home. It was evaluated: (1) different mechanisms to process eggshells and find an easy way to determine the required amount of Ca at home and; (2) the flavor and the texture for eggshell fortified food. Methods: Chemical and mechanical methods of eggshell processing were evaluated. Changes in flavor and texture were evaluated in volunteers coordinated by a professional chef. Results: A single eggshell contains 2.07 0.18 g of Ca; therefore half an eggshell could provide the amount of Ca needed by adult human beings per day. The best way to use chicken eggshell as Ca dietary supplement is powdered to add to bread, pizza or spaghetti as there were small changes in texture and no changes in flavor.

Utilización de centros pigmentarios de Sympterygya bonapartii (Chondrichthyes Rajidae) como herramienta bioanalítica de contaminación; Use of pigmentary centers Sympterygia bonapartii (Chondrichthyes Rajidae) as a tool of pollution bioanalytical Uibrig, Román Armando; Galeano, Noelia Adelina; Schwerdt, Carla Belén; Mas, Javier Diego; Sartuqui, Javier; Guagliardo, Silvia Elizabeth; Acebal, María Florencia; Paolillo, Melisa Andrea; Tanzola, Rubén Daniel Los centros pigmentarios (CPs)se han documentado en anfibios y peces. En estos últimos, aparecen después de la primera alimentación y consisten en la acumulación de pigmentos en células fagocíticas que se asocian con sinusoides y/o centros linfoides en el bazo,el hígado y el pronefros. Han sido utilizados como bioindicadores de contaminación en los peces. La raya marmorada, Sympterygia bonapartii (Müller & Henle, 1841), es un componente habitual del estuario de Bahía Blanca, ecosistema que ha sufrido diferentes presiones de impacto ambiental a lo largo de los últimos 15 años. Se trata de un condrictio bentónico ovíparo que desova en el estuario a fines de primavera y verano. Por sus hábitos bentónicos se lo considera un buen modelo para monitorear el impacto antropogénico en el ecosistema estuarial. El objetivo principal de este estudio fue ensayar la utilización de los CPs de bazo e hígado de Sympterygia bonapartii como bioindicadores de calidad ambiental, bajo un modelo de tratamientocontrol, tomando a la Bahía San Blas como área control de referencia. Se detalló la estructura histológica de los CPs presentes en el bazo e hígado de S. bonapartii. Luego se compararon las posibles diferencias cuali y cuantitativas en los CPs debido a factores ambientales y no ambientales. Se analizaron un total de 52 ejemplares, 27 (20 hembras y 7 machos) se capturaron en el estuario de Bahía Blanca y 25 (16 hembras y 9 machos) en Bahía San Blas.; The pigments centres (CPs) have been documented in amphibious and fi sh. On these last ones, they appear after the fi rst feeding and consist in pigments accumulation of phagocytic cells that associate with sinusoid and/or lymphoid centres on spleen, liver and the pronefros. These have been used as pollution bioindicators on fi sh. The skate, Sympterygia bonapartii (Müller & Henle, 1841), is a usual specimen from Bahía Blanca’s estuary, ecosystem that has suff ered diff erent environmental impact for the past 15 years. This is a bentonic oviparous condictrius which lays eggs in the estuary at the end of spring and summer. Due its bentonic habits, it’s considered a fi ne model to monitor the men’s impact on the estuarial ecosystem. The main objective of this research was to rehearse the use of the spleen and liver’s CPs of Sympterygia bonapartii as environmental bioindicators. This was made following a model of control treatment that takes Bahía San Blas as a referential control area. The histological structure of CPs in spleen and liver of S. bonapartii was determined. After this analysis, the possible qualitative and cuantitative diff erences due to environmental or no environmental infl uences were compared. A number of 52 individuals were analyzed from which 27 (20 females and 7 males) were brought from Bahía Blanca’s estuary. The other 25 individuals (16 females and 9 males) were captured in Bahía San Blas.

La falla en la ovulación como un componente de la patogenia de la enfermedad quística ovárica bovina: rol de citoquinas Baravalle, María Eugenia; Stassi, Antonela Florencia; Velázquez, Melisa María del Luján; Belotti, Eduardo Matías; Ortega, Hugo Hector; Salvetti, Natalia Raquel La ovulación es considerada actualmente como un proceso inflamatorio agudo y a nivel local, las citoquinas cumplen papeles fundamentales debido a que influyen sobre la producción de diversos mediadores. Considerando los múltiples factores que intervienen en estos procesos (ovulación/inflamación), la alteración de uno o más componentes podría contribuir a la patogenia de enfermedades reproductivas como la enfermedad quística ovárica (COD), uno de los desórdenes reproductivos más frecuentes en el ganado bovino lechero. Esta enfermedad provoca cuantiosas pérdidas económicas para la producción pecuaria. En esta revisión, se actualizan conceptos asociados a la interacción entre el sistema inmune y los mecanismos fisiológicos responsables de la ovulación en el bovino.; Ovulation is currently considered an acute and local inflammatory process, and cytokines have fundamentals roles because they influence the production of several mediators. Considering the multiple factors involved in these processes (ovulation / inflammation), the alteration of one or more components may contribute to the pathogenesis of reproductive diseases as cystic ovarian disease (COD), one of the most common reproductive disorders in dairy cattle. This disease causes considerable economic losses for livestock. In this review, we updated concepts associated with the interaction between the immune system and the physiological mechanisms responsible of ovulation in cattle.

Ciudadanía y derechos fundamentales de las personas mayores: de las políticas gerontológicas al derecho de la vejez; Citizenship and human rights for old people: from gerontological policies to elder law Dabove, Maria Isolina En este trabajo se indaga cuáles son los problemas derivados de los paradigmas referidos a la vejez que se han empleado hasta ahora en las políticas sociales y el derecho. También se señalan los caminos que hoy requiere la perspectiva gerontológica del envejecimiento positivo. Se utilizó la metodología de las teorías integrativistas del Derecho y la Política, en las que se reconocen cuatro dimensiones de análisis: plano histórico, sociológico, normativo y valorativo. En la actual era de la globalización, la discriminación negativa por edad avanzada no logra ser revertida por la sola implementación de las políticas públicas gerontológicas. Hace falta desarrollar un modelo de ciudadanía basado en una nueva especialidad: el Derecho de la Vejez sustentado en los Derechos Humanos Fundamentales.; This paper inquires about the problems related to the aging paradigms that have been used so far in social policy and law. It also explores the paths currently required for a gerontological perspective of positive aging. Methodology used was based in integrativism theories of law and policy which recognize four dimensions of analysis: historical background, sociological, normative and evaluative. In the current era of globalization, the negative discrimination due to age cannot be reversed by the mere implementation of public gerontological policies. We need to develop a model of citizenship based on a newspecialty: Elder law supported by Human Rights.