Electrochemical studies on β-carbolines alkaloids: Kinetics of irreversible oxidation processes Madriz Ruiz, Lorean Mercedes; Cabrerizo, Franco Martín; Vargas Balda, Ronald Eduardo The comprehension of the kinetic processes involved in redox reactions with alkaloids such as β-carbolines (βCs) is crucial to unveil differences in the reactivity of these substances. To this end, electrochemical studies on a screen-printed carbon electrode were conducted, revealing the irreversible nature of the process associated with the first oxidation step of norharmane (nHo), harmine (Ha), harmaline (Hlina), harmol (Hol), and harmalol (Hlol). Results from chronoamperometric (CA) studies indicated that in all cases, the oxidation follows a first order reaction. Additionally, cyclic voltammetry (CV) enabled the estimation of the number of electrons transferred (n) as well as the charge transfer coefficient (αa). Finally, square wave voltammetry (SWV) allowed the investigation of the irreversible nature of the oxidative transformations, determining the oxidation potential (EOx) values, and elucidating of the dependency of the frequency-normalized peak current (ip/f) with the frequency (f). For the first time, the rate constant (k) for the selected βCs was determined from the maximum observed in the ip/f vs. f plot. By correlating Ln(k) with EOx values, a linear free energy relationship that show the relevance of molecular structure in reaction pathways was revealed, which constitutes the novelty of this work. These findings are discussed in the context of other redox processes involving βC alkaloids.

First identification of plant remains in earthen architecture of Argentina: constructive and domestic archaeological data from early colonial contexts (16th and 17th centuries) Castillón, Vanina Gisele; Lopez, María Laura; Igareta, Ana Teresa; Capparelli, Aylen This paper analyses, from an archaeological and ethnobotanical perspective, the botanical remains recovered from earthen architecture of Ibatín and Esteco I/II sites, ruins of the first cities established and depopulated in North-western Argentina along the Spanish advance during the 16th and 17th centuries. Sampling procedure, processing of the sediments and identification of botanical macro and microremains, predominantly opal silica phytoliths, were carried out on the basis of standard methodology to identify botanical remains. Diatoms and microcharcoals were also recorded. Additionally, ethnobotanical research was conducted in order to obtain data from local inhabitants related to traditional earth construction techniques and vegetable fibres used in the process. The integration of the results obtained from both approaches allowed us to generate some proposals regarding the techniques for obtaining and using the plants used in the construction activity and associated practices in the region during the colonial period.

Meat Quality Traits in Beef from Heifers: Effect of including Distiller Grains in Finishing Pasture-Based Diets Merayo, Manuela; Pighín, Darío Gabriel; Cunzolo, Sebastian Abel; Veggetti, Mariela Iris; Soteras, Trinidad; Chamorro, Veronica Celeste; Pazos, Adriana Alejandra; Grigioni, Gabriela Maria Distiller grains (DG), which are the by-product from the bioethanol industry, represent an interesting alternative as animal feedstock. To our knowledge, little information is available on the inclusion of DG on the quality of meat from pasture-fed heifers. Thus, the aim of the present study was to evaluate the effect of DG inclusion in pasture-based systems on the main meat quality attributes of Charolais x Aberdeen Angus heifers. For this purpose, meat from heifers fed with a pasture-based diet without supplementation (P) or with 0.75% of live weight DG supplementation (PDG; DG plus dry-rolled corn, 50:50) or with 0.75% of live weight dry-rolled corn supplementation (PRC) was evaluated. Physical (pH, WHC, color, texture), sensory and nutritional (fat content, fatty acid, and amino acid profile) attributes were evaluated in beef samples. No effect of supplementation was observed on meat pH or color (p > 0.05). Meat from PDG heifers showed higher values of WBSF than meat from P heifers (p = 0.039). However, the overall tenderness evaluated by trained panelists showed no differences due to supplementation (p > 0.05). Our results indicate that the inclusion of DG as a partial corn-replacement supplementation for heifers under grazing represents a strategic tool not only related to meat quality, but also as an alternative to reduce food–feed competition.

Population genetic analyses reveal host association and genetically distinct populations of social parasite Solenopsis daguerrei (Hymenoptera: Formicidae) Dekovich, Allyson; Ryan, Sean; Bouwma, Andrew; Calcaterra, Luis Alberto; Silvestre, Rogerio; Staton, Margaret; Shoemaker, DeWayne Inquiline ant social parasites exploit other ant species for their reproductive benefit because they do not possess a worker caste. Due to their relative rarity in nature, the biology and natural history of inquilines are largely unknown. Likewise, not much research exists that details the close relationship between inquilines and their host(s), and how each organism influences the genetic structure of the other. Here, we conducted a comparative population genetics study to assess patterns of genetic structure within and among populations of inquiline Solenopsis daguerrei and its known fire ant hosts, which includes invasive Solenopsis invicta. Using nuclear and mitochondrial markers, we show that four genetically distinct groups of S. daguerrei likely exist, each with different degrees of host association. Consistent with previous inferences of the inquiline lifestyle, we find that inbreeding is common in S. daguerrei, presumably a result of intranidal mating and restricted dispersal. Results from this study, specifically host association patterns, may inform future biological control strategies to mitigate invasive S. invicta populations.

Uso de fototerapia LED para el tratamiento de heridas: amputación en ciervo Axis hembra Vieta, Cecilia; Rivulgo, Virginia Margarita; Sanchez Bruni, Sergio Fabian; Dángelo, Cristian; Lester, Marcelo Fabian; Rosatti, Juan José; Brusco, Jose; García, Jorge El uso de fuentes de luz de radiaciones no ionizantes como Light Emiting Diode (LED) para el tratamiento y el alivio del dolor e inflamación, se conoce como Fototerapia o Fotobiomodulación. La Fototerapia de LEDs de alta potencia instantánea, se genera por la estimulación del diodo semiconductor que produce una luz de muy baja potencia de emisión (1-5 mWatt). Los equipos de LEDs de alta potencia instantánea tienen mayor profundidad de penetración (véase fig. 1) que los LEDs comunes (acción más superficial). Las luces LED se utilizan con una longitud de onda que van desde los 380 a 436 nm (luz violeta), 436 a 495 nm (luz azul), 495 a 566 nm (luz verde), 566 a 589 nm (luz amarilla), 589 a 627 nm (luz naranja), 627 a 780 (luz roja), 770a 940 nm (luz infrarroja). Las mismas son responsables de diversas acciones sobre la célula, incluyendo su permeabilidad, su estimulación de mitocondrias, la síntesis de ATP y sobre proteínas como colágeno y elastina. (McGowan y Goff, 2016;Millis y Levine, 2014; Russel, 2005). A su vez, está documentado que además de acelerar el proceso de cicatrización de heridas, poseen efecto antimicrobiano, antiinflamatorio y analgésico, dependiendo de la longitud de onda utilizada (Tomazoni et al., 2017; Redondo y Sthepens, 2019). Desafortunadamente, al presente hay pocos estudios experimentales en especies superiores sobre los efectos favorables de fototerapia LED en el proceso de cicatrización de heridas (Dall-algon et al. 2009, Farouk et al. 2003, Meyer et al. 2010, Channal, et al., 2008; Deland et al., 2007).

Reducción de Sodio en Quesos Cremosos: Diseño del Proceso de Salado mediante Simulación Computacional Gill, Tomás Ramón; Lanteri, Mario Nicolas; Lespinard, Alejandro Rafael La alta ingesta de sal se asocia con un mayor riesgo de hipertensión arterial y enfermedades cardiovasculares. Los alimentos ricos en sodio, como los lácteos y embutidos, contribuyen significativamente a esta ingesta, lo que resalta la necesidad de reducir el contenido de sal durante su procesamiento. El objetivo de este estudio fue evaluar y diseñar el proceso de salado para quesos cremosos (con humedad del 53% p/p) con concentración estándar de sal (1,2 g/100 g de queso) y versiones reducidas en sodio (0,6 g/100 g de queso). Para lograr este objetivo, se desarrolló un modelo de simulación computacional 3D para predecir la difusión de NaCl en una horma de queso (dimensiones: 0,22 m x 0,22 m x 0,07 m) durante el proceso de salado a diferentes temperaturas (6, 12 y 18°C). El modelo de simulación se basó en la Segunda Ley de Fick y se resolvió numéricamente mediante el Método de Elementos Finitos, utilizando el software COMSOL Multiphysics. Los coeficientes de difusión empleados en el modelo se obtuvieron a partir de estudios previos y variaron según la temperatura, siendo de 3,14x10-10m²s-1 a 6°C, 5,47x10-10 m²s-1 a 12°C y 9,81x10-10 m²s-1 a 18°C. Las simulaciones permitieron predecir la distribución y contenidos medios de sal durante el salado a las diferentes condiciones. Con estos resultados, se determinaron los tiempos de salado necesarios para alcanzar una concentración de sal objetivo. Estos tiempos resultaron ser de 195, 100 y 60 minutos a 6, 12 y 18°C, respectivamente, para los quesos con concentración estándar de sal, mientras que, para los quesos reducidos en sodio, los tiempos fueron de 45, 25 y 15 minutos, respectivamente. El modelo desarrollado demostró ser efectivo para calcular los tiempos de salado a diferentes temperaturas. Además, se observó una reducción significativa del tiempo de salado al aumentar la temperatura y al reducir la concentración de NaCl en un 50%. Los resultados de este estudio serán de gran utilidad para optimizar la producción de quesos cremosos de manera más eficiente y saludable, contribuyendo así a la reducción del riesgo de enfermedades cardiovasculares asociadas con el alto consumo de sodio.

Frailty status improvement after kidney transplantation Aroca Martinez, Gustavo; Hernandez Agudelo, Sandra; Castro Hernández, Christian; Cabarcas Barbosa, Omar; Terrasa, Sergio Adrian; González Torres, Henry J.; Cadena Bonfanti, Andrés; Musso, Carlos Introduction: Frailty is a clinical syndrome characterized by a decrease in strength, resistance and body physiological condition, making the individual more vulnerable, and increasing his/her risk of dependence and death. Kidney transplant (KT) is currently the best end-stage renal disease therapeutic alternative for certain individuals. Frailty status occurs in approximately 20% of KT patients. Thus, it was evaluated if there would be any change in frailty status level in a population of adult patients on chronic HD after receiving KT. Material and method: A cross-sectional study was conducted on a population of adult hemodialysis patients (n: 57), with the objective of evaluating if there was a significant change in their clinical frailty score (CFS) after 6 months of KT. For the statistical analysis, the Student’s t-test, and the test of statistical significance between two proportions were applied. Results: Mean CFS before KT was 4 (vulnerable), and after KT was 3 (robust). CFS value was significantly lower after KT (p value < 0.01). Conclusion: A significant improvement was found between pre- and post-transplant clinical frailty scores in hemodialysis adult patients.

Evidence of biotic interactions through shell repair on Early Cretaceous gastropods from west-central Argentina Cataldo, Cecilia Soledad; Luci, Leticia; Fernández, Diana Elizabeth; Andrada, Alejandra Mariel; Lazo, Dario Gustavo; Aguirre Urreta, María Beatriz Evidence of durophagous predatory behavior on benthic invertebrates in the Upper JurassiceLower Cretaceous of the Neuquen Basin is scarce, despite the abundant record of potential predators. Herein, we document shell repair in one gastropod from lower Barremian marginal-marine deposits in northern Neuquen Basin, Argentina. This is the first report of shell repair on Early Cretaceous gastropods from Argentina and of shell repair frequencies from the Lower Cretaceous. Paleoanculosa macrochilinoides shells from three sections of the La Tosca Member (Huitrín Formation) in Mendoza province were studied. We described and interpreted the repaired breakage, calculated repair frequencies which were compared among localities, tested for geographic differences in size distribution of total samples and of repaired vs. undamaged shells, and assessed whether this species reached a size refuge. Studied shell repair consists of fractures cutting through growth lines roughly diagonally, from suture to suture, and near the aperture, thus representing apertural damage. Given its stereotypical nature, the damage represents the record of a biotic interaction, likely sublethal predation, instead of diagenetic compaction or damage by physical disturbance. Repair frequencies are low, indicating that shell architecture made P. macrochilinoides susceptible to lethal predatory attacks, or else that there were few predator-prey encounters. There are no major geographic differences regarding repair frequency, size distribution, and preservation. Likely, P. macrochilinoides did not reach a size refuge. This study provides evidence from both a time slice and geographic area with scarce data on crushing predation and from an inbetween phase within the Mesozoic Marine Revolution.

Evidence of drilling predation in oysters from the Lower Cretaceous of the Neuquén Basin (Argentina) and its implications for Mesozoic predation trends Toscano, Agustina Gabriela; Cataldo, Cecilia Soledad; Luci, Leticia; Lazo, Dario Gustavo The study of trace fossils recorded on organic substrata is vital to the understanding of past biotic interactions. Here, oyster valves with circular holes are reported from the Lower Cretaceous (Berriasian to lower Valanginian) strata of the Neuquén Basin. From a total of 1318 oyster specimens, 17 valves presented 19 of these traces, which were studied to determine their origin, frequency and whether taxon, size and/or site selectivity existed. The studied traces, identified as Oichnus isp. (O. paraboloides in three cases), were recorded on four oyster species belonging to three genera: Aetostreon, Ceratostreon, and Nanogyra. Boring frequency was low (maximum = 0.103), and although traces were recorded exclusively on oysters, no taxon selectivity was found. No differences were found between the size of bored versus intact valves. The traces, although mostly recorded on left valves, showed a random distribution within valves, indicating no size or site selectivity. Hole morphology, absence of attachment scars and multiple holes point to a predatory origin. The lack of stereotypy indicates a generalist or facultative producer. Similar traces are usually ascribed to gastropod producers (i.e., naticids or muricids), but the gastropods co-occurring with the studied oysters lack any extant relative with a drilling apparatus. Hence, the producer remains unknown. This record contributes to the filling of the so-called early Mesozoic gap in drilling predation evolutionary history, during which two predation trends seem to have co-occurred: a background type of predation, carried out by generalists or facultative predators, and the rise of highly specialized predators, associated with the emergence of naticids and muricids.

Bovine infectious abortion: A systematic review and meta-analysis Hecker, Yanina Paola; González Ortega, Sara; Cano, Santiago; Ortega Mora, Luis Miguel; Horcajo, Pilar The aim of the present systematic review and meta-analysis was to identify the main infectious agents related to bovine abortion worldwide in the period between 2000 and 2022. First, we investigated the global prevalence of infectious agents related to bovine abortion. For this analysis, only 27 articles detected of a wide panel of agents were included. The random effects model revealed that the estimated prevalence of the abortifacient agents in bovine abortion was 45.7%.The heterogeneity among studies was high, but Egger’s test showed that there was no publication bias, even though the total number of samples analyzed in these articles was variable. There was no significant effect of the year of the study publication on the estimated prevalence, although an increasing trend was observed over time, possibly due to the implementation of new diagnostictechniques. Then, we analyzed the prevalence of the main transmissible agents in bovine abortion. For this analysis, 76 studies that analyzed 19,070 cases were included. Some infectious agent was detected in 7,319 specimens, and a final diagnosis was reached in 3,977 of these, when both the infectious agent and compatible histopathological changes were detected. We found that Neosporacaninum was the most detected agent (22.2%), followed by opportunistic bacteria (21.4%), Chlamydiaceae family (10.9%) and Coxiella burnetii (9.5%). Regarding viral agents, bovine herpes virus type 1 and bovine viral diarrhea displayed similar prevalence rates (approximately 5%). After considering the description of specific histopathological changes, our analyzes showed that N. caninum was a confirmed cause of abortion in 16.7% of the analyzed cases, followed byopportunistic bacteria (12.6%) and Chlamydia spp. (6.8%); however, C. burnetii was only confirmed as a cause of abortion in 1.1% of the cases. For all agents, the heterogeneity among studies was high, and the subgroup analyzes discarded the diagnostic method as the cause of such heterogeneity. This study provides knowledge about the global prevalence of the different infectious agents related to bovine abortion, the most coming of which is N. caninum. In addition, this review reveals the existing deficiencies in the diagnosis of bovine abortion that must be addressed in the future.

Perspectives from the 2022 cohort of the American Chemical Society Summer School on Green Chemistry & Sustainable Energy Saraf, Mohit; Roy, Monika A.; Yarur Villanueva, Francisco; Kundu, Anirban; Tran, Hung-Vu; Ghosh, Moumita; Ezenwa, Sopuruchukwu; Gastelu, Gabriela; Prebihalo, Emily A.; Cala Gómez, Luis Javier; Cleary, Scott R.; Devineni, Geetesh; Lee, Gahyun Annie; Umenweke, Great C.; Koby, Ross F.; Nixon, Rachel; Voutchkova, Adelina; Moores, Audrey The field of chemistry is uniquely equipped to solve many current and impending global challenges; however, minimizing potential negative impacts on the environment, society, and the economy requires a holistic approach to developing new processes and chemicals. For this reason, there is an urgent need to incorporate green chemistry and systems thinking into chemistry-based disciplines so that the most sustainable, least toxic, and least resource-intensive research directions and methods are prioritized. The next generation of researchers and instructors is poised to implement these approaches; however, most graduate curricula do not include coursework on green chemistry and systems thinking. Every year, the American Chemical Society Green Chemistry Institute hosts the Summer School on Green Chemistry & Sustainable Energy for early career researchers to learn about green chemistry and systems thinking approaches for tackling sustainability goals. In this Perspective, 2022 summer school participants highlight sustainability challenges in their own work that can be addressed using the skills and knowledge acquired at the summer school, including in carbon capture, organic pharmaceutical synthesis, nanomaterial synthesis, catalysis, and other areas. In addition, how green chemistry can meet practical needs in industry settings and be infused in education and government policy is discussed.

Producción de Agregados Porosos Livianos En la región de Olavarría, centro de la provincia de Buenos Aires, se cuenta con un amplio stock de lutitas, obtenido del destape de las canteras de caliza utilizada para la elaboración del clinker Portland. Las lutitas están compuestas principalmente por cuarzo y los minerales arcillosos illita y clorita, siendo una materia prima con potencial para producir agregados porosos. El objetivo de esta línea de investigación es caracterizar las lutitas y evaluar su uso como materia prima en la elaboración de agregados porosos livianos, con y sin la incorporación de agentes formadores de poros. Los agregados porosos presentan un elevado aislamiento térmico, son ignífugos y absorben el sonido, lo que permite su aplicación en diversas áreas de la construcción.

Hacia una poética de la distancia o el linaje místico de Migraciones (2022) de Gloria Gervitz; Towards a poetics of distance or mystical lineage of Migraciones (2022) by Gloria Gervitz León, Denise En el presente ensayo me detendré en los modos en los que la poeta judeo mexicana Gloria Gervitz (1943-2022) se apropia de la tradición mística judeocristiana y la inscribe en su obra poética reunida bajo el título de Migraciones. En La huella del otro, Emmanuel Levinas contrapone las figuras míticas de Ulises y Abraham, encontrando allí algo así como una diferencia básica entre el pensamiento griego y el pensamiento judío. A diferencia de Ulises, que logrará regresar transformado a su Ítaca natal, Abraham abandona su lugar de nacimiento para arrojarse a un exilio radical sin vuelta atrás. Así, la figura del sujeto errante se convierte en un rasgo definitorio de esa nación flotante, vaga e inaprensible del judaísmo. En esta dirección específica es que me interesa indagar los modos en los que la poesía de Gervitz aloja las experiencias concretas y metafóricas de diásporas y desplazamientos de una genealogía femenina reivindicando los trayectos negados y los itinerarios de las mujeres de la familia.; In this essay I will focus on the ways in which the Judeo-Mexican poet Gloria Gervitz (1943-2022) appropriates the Judeo-Christian mystical tradition and inscribes it in her poetic work gathered under the title of Migrations. In The Footprint of the Other, Emmanuel Levinas contrasts the mythical figures of Ulysses and Abraham, finding there something like a basic difference between Greek thought and Jewish thought. Unlike Ulysses, who will manage to return to his native Ithaca transformed, Abraham leaves his birthplace to throw himself into a radical exile with no turning back. Thus, the figure of the wandering subject becomes a defining feature of that floating, vague and elusive nation of Judaism. It is in this specific direction that I am interested in enlightening the ways in which Gervitz’s poetry hosts the concrete and metaphorical experiences of diasporas and displacements of a female genealogy claiming the denied paths and itineraries of the women in the family.

Glycosylated-drug Delivery as Targeted Therapy for Hepatocellular Carcinoma: Are We There Yet? Sukowati, Caecilia H.C.; Weiz, Gisela; Lestari, Witri W.; Tiribelli, Claudio Rapid advances in biotechnologies have opened a new landscape of anticancer therapies, particularly in the development of novel molecular targeted drugs. This works also for hepatocellular carcinoma (HCC), the most common type of liver cancer and the third leading cause of cancer-related death world- wide [1]. The growing knowledge of HCC pathophysiology and its molecular and cellular aspects sub- stantially enhances the progress of new molecular drugs. For instance, sorafenib, the first molecular tar- geted therapy approved for HCC in 2007, remained the only available standard of care for advanced HCC for a decade. However, in the last 5 years, the introduction of new molecular drugs has been evolving rapidly with the approval of additional first- and second-line treatments. In the last 2 years, the emerging potential of immunotherapy, such as immune checkpoint inhibitors, both as single agents and in combination therapies, further increased the success of the HCC treatment regimens [2]. Nevertheless, specific tar- geting of these molecular drugs in HCC is still far from the clinical setting, particularly how to specifically deliver the drug(s) to the cancer cell and how effectively the drugs may inhibit cancer growth with minimal toxicity to normal cells.

Ecosystem stability of temperate grasslands in response to variability of hydrological conditions Lara, Bruno Daniel; Vercelli, Natalia; Entraigas, Ilda; Scaramuzzino, Rosa Lourdes; Gandini, Marcelo Luciano; Salese, Sofía; Goyenetche, Juan Manuel The relationship between biodiversity and the stability of ecosystem functioningover time has been widely studied. The current global context has refloated thistopic for biodiversity´s role in buffering the effects of different disturbances. Ingeneral, the results of these studies show that ecosystem functioning is morestable over time in more diverse systems. However, these results are derivedfrom empirical research on small-scalestudies, where species and disturbancesconditions are manipulated. In this work, we used climate and floristic informationdata obtained from surveys over an extended period on Flooding Pampagrasslands (Argentina) with a remotely sensed indicator of the stability of netprimary productivity at a regional scale over a broad temporal range to evaluatethe relationship between species diversity and the stability of ecosystem functioningunder different water conditions. We found a close correlation betweenNormalized Difference Vegetation Index responses of natural grasslands andclimate variability in the study area. Besides, grasslands with higher speciesrichness and diversity showed greater stability in ecosystem functioning at differentwater conditions. The results obtained could be relevant in natural resourcemanagement for the close relationship between diversity–stabilityin a local andregional productive context characterized by a simplified landscape of spaceand time.

Strontium isotope mapping and its application to study the fish life history (Salminus brasiliensis) in semi-fragmented rivers (La Plata Basin, South America) Avigliano, Esteban; Chung, Ming Tsung; Pouilly, Marc; Huang, Kuo Fang; Casalinuovo, Miguel; Dominino, Jael; Silva, Natalia Andrea; Sánchez, Sebastián; Facetti, Juan F.; Volpedo, Alejandra Salminus brasiliensis is one of the largest and most important commercial and sporting fish species in South America, of which little is known about its habitat use, especially in semi-fragmented rivers. The aims of this study were to expand the water 87Sr/86Sr baseline of the La Plata Basin, and to study the migratory patterns of S. brasiliensis from Paraná dam-free stretch and a representative tributary semi-fragmented using otolith isotopic chemistry. Water samples were collected at 10 sites on the upper Paraná River and two sites on the middle and lower Carcarañá Basin (tributary of the lower Paraná River). Fourteen fish were caught in the upper Paraná River and 13 in two sites of the middle and lower Carcarañá Basin. 87Sr/86Sr was measured in water and otolith core-to-edge transect by MC-ICPMS and LA-MC-ICPMS, respectively. Water results were incorporated into a dataset with 53 other sampling points from the La Plata Basin and subjected to a cluster analysis, which resulted in nine differentiable chemical signatures. Discriminant analysis confirmed the presence of at least eight contrasting isotopic signals. Based on the otolith core 87Sr/86Sr, four individuals from the upper Paraná River were classified as originating from Paraguay sub-basin, while the rest were assigned to Paraná River. All fish from the Carcarañá sub-basin were classified as originating from the Paraná River, except two individuals which were assigned to the Carcarañá sub-basin. Results indicated that the fish run up the Carcarañá sub-basin overcoming up to three open spillways, and could live there for years and even reproduce. However, the Paraná River had the largest contribution to the fish caught in both the upper Paraná River and the Carcarañá sub-basin.

O hatha-yoga no Serviço de Orientação ao Exercício (SOE) em Vitória: liberdade e estilo de vida; Hatha-yoga in the Exercise Guidance Service (SOE) in Vitória: freedom and lifestyle; Hatha-yoga em el Servicio de Orientación del Ejercicio (SOE) em Vitória: libertad y estilo de vida Ribeiro e Silva Gomes, Ligia; Quintão de Almeida, Felipe; Galak, Eduardo Este artigo aborda os usos do hatha-yoga como parte da oferta do Serviço de Orientação ao Exercício (SOE), vinculado à Secretaria Municipal de Saúde (Semus), da cidade de Vitória (ES). Utilizando como estratégia metodológica entrevistas semiestruturadas, aplicação de questionários e diário de campo, tem como objetivo interpretar as motivações vinculadas às escolhas pelo yoga, uma prática corporal que integra espiritualidade e bem-estar nas aulas do serviço público em Vitória. Conclui-se que as estruturas e a reflexividade fazem parte do repertório de ação para que as pessoas consigam acionar projetos de vida que os tirem de situações de insegurança e risco social.; This article discusses the uses of hatha-yoga as part of the Exercise Guidance Service (SOE), linked to the Municipal Health Department (Semus), at Vitória (ES). Using semi-structured interviews as a methodological strategy, the application of questionnaires, and a field diary, the aim is to interpret the motivations linked to the choices for yoga, a body practice that integrates spirituality and well-being, in public service classes in Vitória. It is concluded that structures and reflexivity are part of the action repertoire so that people can trigger life projects that take them out of situations of insecurity and social risk.; Este artículo discute los usos del hatha-yoga como parte del Servicio de Orientación del Ejercicio (SOE), vinculado a la Secretaría Municipal de Salud (Semus), en la ciudad de Vitória (ES). Utilizando como estrategia metodológica entrevistas semiestructuradas, la aplicación de cuestionarios y el diario de campo, el objetivo es interpretar las motivaciones vinculadas a las elecciones por el yoga, práctica corporal que integra espiritualidad y bienestar en las clases de servicio público en Vitória. Se concluye que las estructuras y la reflexividad forman parte del repertorio de acción para que las personas puedan desencadenar proyectos de vida que las saquen de situaciones de inseguridad y riesgo social.

Challenges in the Detection and Attribution of Northern Hemisphere Surface Temperature Trends Since 1850 Connolly, Ronan; Soon, Willie; Connolly, Michael; Baliunas, Sallie; Berglund, Johan; Butler, C. J.; Cionco, Rodolfo Gustavo; Elias, Ana Georgina; Fedorov, Valery M.; Harde, Hermann; Henry, Gregory W.; Hoyt, Douglas V.; Humlum, Ole; Legates, David R.; Scafetta, Nicola; Solheim, Jan-Erik; Szarka, László; Velasco Herrera, Víctor M.; Yan, Hong; Zhang, Weijia Since 2007, the Intergovernmental Panel on Climate Change (IPCC) has heavily relied on the comparison between global climate model hindcasts and global surface temperature (ST) estimates for concluding that post-1950s global warming is mostly human-caused. In Connolly et al., we cautioned that this approach to the detection and attribution of climate change was highly dependent on the choice of Total Solar Irradiance (TSI) and ST data sets. We compiled 16 TSI and five ST data sets and found by altering the choice of TSI or ST, one could (prematurely) conclude anything from the warming being "mostly human-caused" to "mostly natural." Richardson and Benestad suggested our analysis was "erroneous" and "flawed" because we did not use a multilinear regression. They argued that applying a multilinear regression to one of the five ST series re-affirmed the IPCC's attribution statement. They also objected that many of the published TSI data sets were out-of-date. However, here we show that when applying multilinear regression analysis to an expanded and updated data set of 27 TSI series, the original conclusions of Connolly et al. are confirmed for all five ST data sets. Therefore, it is still unclear whether the observed warming is mostly human-caused, mostly natural or some combination of both.

Uses of the Biographical Approach: The Construction of Youth Technobiographies Lemus, Magdalena; Benitez Larghi, Hector Sebastian In this article, we report on our analysis as part of a research project conducted from2012 to 2018, and we explore the potential of the biographical approach in studying the appropriation of digital technologies (DTs). The biographical approach (SAUTÚ, 2012) is described as a theoretical-methodological strategy to address how people, through time and space and within the framework of certain cultural and socioeconomic contexts, connect with various digital technologies and how they construct meanings, practices, and relationships. With the analysis of a series of techno biographies (CHING & VIGDOR, 2005) of young people, we reflect on the ability of the method to capture the symbolic dimension of access to DTs, reconstruct the acquisition of digital skills and their role in educational transitions, and understand the links between biographical trajectories and broader social processes, such as those that constitute and reproduce social inequalities in contemporary societies. We show that techno biographies are a useful construct to identify repetitions, trends, and patterns of behavior, but also to pinpoint anything that is out of the ordinary in the paths of the appropriation of DTs of each particular group.

Ciudades y territorios para la vida: La concepción autogestionaria del hábitat Rodriguez, Maria Carla La etapa actual del capitalismo financiarizado ha potenciado los procesos de urbanización generalizada, provocando el fenómeno de explosión/implosión de las ciudades anticipado por Henry Lefebvre en 1970. En América Latina, esto ha profundizado el desarrollo territorial desigual: se exacerba la microsegración a la par de la expansión desmesurada de las superficies urbanizadas que alimentan el maldesarrollo y la crisis ambiental.