Bacterioterapia con lactobacilos probióticos para la prevención de infecciones urogenitales Nader, Maria Elena Fatima Los lactobacilos son los microorganismos predominantes en el tracto gastrointestinal y urogenital del hombre y los animales homeotermos. También se emplean en la elaboración de diferentes alimentos, lo que los categoriza como GRAS (generally regarded as safe). Si bien están disponibles en productos vaginales en el mercado farmacéutico, hay escasas evidencias de su efectividad para la prevención de infecciones urogenitales. Nuestro grupo de trabajo ha aislado lactobacilos vaginales humanos, seleccionando aquellos con propiedades benéficas o probióticas. Se han estudiado las características tecnológicas para obtener el mayor número de microorganismos vivos (biomasa) y las condiciones para la producción óptima de sustancias antagónicas frente a patógenos urogenitales (ácidos orgánicos, peróxido de hidrógeno, bacteriocinas). Se ha demostrado en animales de experimentación (ratones BALB/c hembra endocriados) que la administración intrauretral de lactobacilos no produce efectos adversos ni modificaciones estructurales o ultraestructurales, previniendo eficazmente las infecciones urinarias. Es necesaria la complementación de estos resultados con estudios en pacientes para demostrar la efectividad de la administración intravaginal de los lactobacilos probióticos seleccionados en la recolonización de la microbiota urogenital, la prevención o la terapia de los diferentes síndromes y cuadros clínicos que afectan al tracto, su efecto sobre las embarazadas, etc., que permitan proponer la bacterioterapia con lactobacilos como alternativa válida a la terapia con otras drogas.; Lactobacilli are the predominant microorganisms in the gastrointestinal and urogenital tracts of human beings and homeotermic animals. They are also used for the elaboration of different fermented foods being categorized as GRAS (generally regarded as safe). Even though they are included into different vaginal products in the pharmaceutical market, there are small amount of evidences of their effectivity in the prevention of urogenital infections. Our research group have isolated human vaginal lactobacilli, selecting those with beneficial or probiotic properties. The technological characteristics to obtain the higher number of viable (biomass) microorganisms and the conditions for the optimal production of antagonistic substances against pathogenic microorganisms (organic acid, hydrogen peroxide, bacteriocins) were determined. In experimental animals (inbreed female BALB/c mice) we demonstrated that the intraurethral administration of lactobacilli does not produce adverse effects or structural or ultra structural modifications in the urogenital tract, preventing effectively the urinary tract infections. The complementation of these results with human assays is necessary to demonstrate effectively the intravaginal administration of selected probiotic lactobacilli on the recolonization of the urogenital microbiota, the prevention or therapy of different clinical syndromes, their effect on pregnant women, etc, that will allow the proposal of the bacteriotherapy with lactobacilli as a valid alternative to the other drugs therapies.

Compensatory renal growth protects mice against Shiga toxin 2-induced toxicity Camerano, Gabriela Veronica; Bustuoabad, Oscar David; Meiss, Roberto Pablo; Gómez, Sonia Alejandra; Fernández, Gabriela Cristina; Isturiz, Martín Amadeo; Palermo, Marina Sandra; Dran, Graciela Isabel Uninephrectomy (Unx) is followed by the compensatory renal growth (CRG) of the remaining kidney. Previous evidence has shown that during CRG, renal tissue is resistant to a variety of pathologies. We tested the hypothesis that the functional changes that take place during CRG could attenuate Shiga toxin (Stx) toxicity in a mouse model of Stx2-induced hemolytic uremic syndrome (HUS). The participation of nitric oxide (NO) was analyzed. After CRG induction with Unx, mice were exposed to a lethal dose of Stx2, and the degree of renal damage and mortality was measured. Stx2 effects on the growth, renal blood flow (RBF) and NO synthase (NOS) intrarenal expression in the remaining kidney were then studied. The induction of CRG strongly prevented Stx2-mediated mortality and renal damage. Administration of the NOS inhibitor NG-nitro-L-arginine methyl ester (L-NAME) during CRG partially impaired the protection. Both Stx2 and L-NAME interfered with the hypertrophic and hyperplastic responses to Unx, as well as with the increase in RBF. In intact mice, Stx2 decreased renal perfusion, inhibited endothelial NOS basal expression and enhanced inducible NOS expression; all of these effects were attenuated by prior Unx. It is concluded that during CRG mice are highly protected against Stx2 toxicity and lethality. The protective capacity of CRG could be related to the enhancement of renal perfusion and preservation of eNOS renal expression, counterbalancing two major pathogenic mechanisms of Stx2.

Response to Comment on "Cathepsin-L Influences the Expression of Extracellular Matrix in Lymphoid Organs and Plays a Role in the Regulation of Thymic Output and of Peripheral T Cell Number" Lombardi, Gabriela; Burzyn, Dalia; Mundiñano, Juliana; Berguer, Paula Mercedes; Costa, Hector Luis; Goldman, Alejandra; Piazzon, Margarita Isabel; Nepomnaschy, Irene In our article published in The Journal of Immunology in June 1, 2005 (1), we reported that lymph nodes from nackt mice (CTSLnkt/CTSLnkt) are hypertrophied, showing a normal absolute number of CD4+ T cells and a marked increase in the number of CD8+ T lymphocytes. Correlatively, extracellular matrix (ECM) components were found to be increased. Contrarily, in nackt thymus, laminin, fibronectin, and collagen I and IV are markedly decreased, with an augmented output of CD8+ cells. We also reported that a mutated form of cathepsin L can be detected in different organs in nackt mice. These results demonstrate that the nackt mutation in the Ctsl gene influences the levels of ECM components in lymphoid organs, the thymic output, and the number of T cells in the periphery, thus broadly affecting the immune system.

Environmental control of phenological development in two Lesquerella species Windauer, Liliana; Slafer, Gustavo Ariel; Ravetta, Damián Andrés; Benech-Arnold, Roberto Luis Lesquerella fendleri and Lesquerella mendocina are two species with potential for domestication as crops for semiarid regions. Understanding the environmental influences on development is a critical step for the introduction of a wild species into cultivation. Under controlled conditions these species responded differently to temperature: L. fendleri phenological approach toward flowering responded linearly to temperature, whereas initiation of flowering in L. mendocina was relatively insensitive to temperature. L. fendleri exhibited a quantitative response to supra-optimal temperatures (with rate of development reduced with further increases in temperature) whereas L. mendocina showed a qualitative response, no flower development at supra-optimal temperatures. In this work undertaken in the field we studied phenological development in L. fendleri and L. mendocina as a function of planting date, quantified the time required to reach particular phenological stages under the various thermal environments, and compared these results with those previously obtained with controlled conditions. We also studied the influence of photoperiod on plant phenology in field situations and through experiments done under controlled conditions. Development rate for both species varied with sowing date with plant cycles shorter in spring sown plants, even if measured in thermal time. L. mendocina plants sown in late spring displayed a biennial cycle. These results are consistent with those obtained under controlled conditions. However, cycle shortening in thermal time with delays in sowing date suggested that factors other than temperature also influenced phenology of these two species. Further studies under controlled conditions showed that phenological development of L. fendleri plants was also altered by photoperiod, with plants displaying a typical long-day response. At the highest temperatures used in these studies L. mendocina plants did not respond to photoperiod. The possibility that incident radiation is involved in L. mendocina response to sowing date is discussed.

Oblique projections and frames Antezana, Jorge Abel; Corach, Gustavo; Ruiz, Mariano Andres; Stojanoff, Demetrio We characterize those frames on a Hilbert space H which can be represented as the image of an orthonormal basis by an oblique projection defined on an extension K of H. We show that all frames with infinite excess, and frame bounds 1 ≤ A ≤ B,are of this type. This gives a generalization of a result of Han and Larson which only holds for normalized tight frames.

Effects of pH and electrolyte concentration on the binding between a humic acid and an oxazine dye Zanini, Graciela Pilar; Avena, Marcelo Javier; Fiol, Sarah; Arce, Florencio The binding between an oxazine dye and a humic acid was studied in aqueous solutions in the pH range 4-10 and in the supporting electrolyte (KCl) range 0.001-0.1 M. A rather simple spectrophotometric method was developed to construct binding isotherms under conditions were traditional centrifugation or filtration methods fail. The use of this method is possible because humic acid molecules have the ability of changing the spectrum of dye molecules, and this ability is used to quantify the isotherms. All binding isotherms have a Langmuirian shape. The amount of bound dye is strongly dependent on the ionic strength and less dependent on the pH of the solution. The binding is rather strong and mainly driven by non-electrostatic forces. Whereas the Langmuir binding constant is independent of the pH and electrolyte concentration, the number of assessable sites in humic acid for binding oxazine increases by increasing pH and decreasing electrolyte concentration. These results can be directly related to the flexibility of humic acid molecules, which can swell at high pH and low ionic strength, increasing consequently the availability of binding sites. The results also indicate that humic substances may strongly affect the mobility and fate of dyes and related pollutants in the environment.

Arbitrary divergence speed of the least-squares method in infinite-dimensional inverse ill-posed problems Spies, Ruben Daniel; Temperini, Karina Guadalupe A standard engineering procedure for approximating the solutions of an infinite-dimensional inverse problem of the form Ax = y, where A is a given compact linear operator on a Hilbert space X and y is the given data, is to find a sequence {XN} of finite-dimensional approximating subspaces of X whose union is dense in X and to construct the sequence {xN} of least-squares solutions of the problem in X N. In 1980, Seidman showed that if the problem is ill-posed, then, without any additional assumptions on the exact solution or on the sequence of approximating subspaces XN, it cannot be guaranteed that the sequence {xN} will converge to the exact solution. In this paper, this result is extended in the following sense: it is shown that if X is separable, then for any y ∈ X, y ≠ 0 and for any arbitrarily given function there exists an injective, compact linear operator A and an increasing sequence of finite-dimensional subspaces XN ⊂ X such that for all, where xN is the least-squares solution of Ax = y in XN. © 2006 IOP Publishing Ltd.

A proposed Global Boundary Stratotype Section and Point for the base of the Middle Ordovician Series: The Niquivil section, Precordillera of San Juan, Argentina Albanesi, Guillermo Luis; Carrera, Marcelo Gabriel; Cañas, Fernando Luis; Saltzman, Matthew The Niquivil section, Argentine Precordillera, fulfills most of the requirements for a Global Stratotype Section and Point (GSSP) for the base of the Middle Ordovician Series. It has excellent conodont biostratigraphy in a continuous succession of uniform lithology, is readily accessible, and the critical interval is not tectonically affected. The position of the Lower/Middle Ordovician Series boundary in the Central Precordillera is placed at the middle part of the San Juan Formation, an open-platform carbonate unit. The Niquivil section is proposed as a GSSP for the base of the Middle Ordovician, which is marked by the FAD of the conodont Cooperignathus aranda (Cooper). It occurs in level NCA, at the upper part of the Oepikodus evae Zone (overlapping uppermost records of O. evae in association with other guide species); i.e., 100.15 m above the base of the reference section. The auxiliary Peña Sombría section from northern Precordillera records graptolites of the lower (but not lowest) Middle Ordovician in the Isograptus victoriae maximus Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).Cooperignathus aranda (Cooper). It occurs in level NCA, at the upper part of the Oepikodus evae Zone (overlapping uppermost records of O. evae in association with other guide species); i.e., 100.15 m above the base of the reference section. The auxiliary Peña Sombría section from northern Precordillera records graptolites of the lower (but not lowest) Middle Ordovician in the Isograptus victoriae maximus Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).(Cooper). It occurs in level NCA, at the upper part of the Oepikodus evae Zone (overlapping uppermost records of O. evae in association with other guide species); i.e., 100.15 m above the base of the reference section. The auxiliary Peña Sombría section from northern Precordillera records graptolites of the lower (but not lowest) Middle Ordovician in the Isograptus victoriae maximus Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).Oepikodus evae Zone (overlapping uppermost records of O. evae in association with other guide species); i.e., 100.15 m above the base of the reference section. The auxiliary Peña Sombría section from northern Precordillera records graptolites of the lower (but not lowest) Middle Ordovician in the Isograptus victoriae maximus Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).O. evae in association with other guide species); i.e., 100.15 m above the base of the reference section. The auxiliary Peña Sombría section from northern Precordillera records graptolites of the lower (but not lowest) Middle Ordovician in the Isograptus victoriae maximus Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).Isograptus victoriae maximus Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).Zone, few meters above the proposed boundary biohorizon. The range of C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).C. aranda can be correlated with the I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).I. victoriae lunatus Zone up to the lower part of the Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).Undulograptus austrodentatus Zone in diverse sections of the world. C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).C. aranda presents cosmopolitan distribution and occurs in virtually all environments. The proposed GSSP preserves a carbon-isotope record that provides an auxiliary marker of potential global application. Radiometric dating of K-bentonite samples, interbedded with carbonate strata yielding lower records of C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).C. aranda, were recovered from the auxiliary Talacasto section in Central Precordillera (469.8 ± 2.3 Ma, U–Pb SHRIMP dating).

Herramientas para la gestión del uso público en espacios naturales: Procesos participativos; Tools for the management of public use4n wetlands: Public participation De Paula, Malena; Huwiler, Cristina; Viñals, María José; Morant González, Maryland; Ferrer, Carlos; Cabrelles, Gemma; Rigoberto, Noelia; Quintana, Ruben Dario La gestion del uso publico en areas naturales y especialmente en Humedales de Importancia Internacional(Sitios Ramsar), representa un importante reto para planificadores y gestores del territorio que tratan deconjugar la conservation de los valores ecologicos y culturales con la utilidad publica, en areas que se caracterizan por una gran fragilidad ecosistemica.El trabajo parte de la premisa de que la participation de las comunidades locales involucradas en laplanificacion y gestion del uso publico en humedales es la via para asegurar que la mayor parte de los beneficiosque se generen permanezcan en la comunidad y para que se garantice la conservation y restauracion de laintegridad ecologica de los humedales.En este documento se expone el diseño e implementation de herramientas metodologicas de una EstrategiaParticipativa. Se analizan a traves de diferentes casos de estudio los resultados de la aplicacion de dicha metodologia, a distintas situaciones de las comunidades locales respecto a los procesos participativos, en relationcon la planificacion de los humedales y el uso publico.; Community involvement and participation in management decision making for public use of natural areas, and particularly in Wetlands of International Importance (Ram sarsites) and other wetlands, have been recognized as the best way compatible with the maintenance of the cultural values and the natural properties of the ecosystem . This paper was conceived with the premise that local people involvement in wetlands management encouraged by a participative strategic can substantially contribute significantly to maintaining or restoring the ecological integrity of wetlands, as well as contributing to community well being and more equitable access to resources. Through the case studies presented here, the methodology is analyzed in different local communities situations from the point of view of participatory processes for the management of wetlands and the public use.

Personalizing user-agent interaction Schiaffino, Silvia Noemi; Amandi, Analia Adriana Interface agents are computer programs that provide personalized assistance to users with their computer-based tasks. The interface agents developed so far have focused their attention on learning a user´s preferences in a given application domain and on assisting him according to them. However, in order to personalize the interaction with users, interface agents should also learn how to best interact with each user and how to provide them assistance of the right sort at the right time. To fulfil this goal, an interface agent has to discover when the user wants a suggestion to solve a problem or deal with a given situation, when he requires only a warning about it and when he does not need any assistance at all. In this work, we propose a learning algorithm, named WoS, to tackle this problem. Our algorithm is based on the observation of a user´s actions and on a user´s reactions to the agent´s assistance actions. The WoS algorithm enables an interface agent to adapt its behavior and its interaction with a user to the user´s assistance requirements in each particular context.

Post-prior discrepancies in CDW-EIS calculations for ion impact ionization fully differential cross sections Ciappina, Marcelo Fabián; Cravero, Walter Ruben In this work we present fully differential cross sections (FDCSs) calculations using post and prior versions of CDW-EIS theory for helium single ionization by 100 MeV C6+ amu-1 and 3.6 MeV amu -1 Au24+ and Au53+ ions. We performed our calculations for different momentum transfer and ejected electron energies. The influence of internuclear potential on the ejected electron spectra is taken into account in all cases. We compare our calculations with absolute experimental measurements. It is shown that prior version calculations give better agreement with experiments in almost all studied cases.

Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation Dekanty, Andres; Sauane, Moira; Cadenas, Belen; Coluccio Leskow, Federico; Barrio, Maria Marcela; Casala, Jorgelina; Paciencia, Mercedes; Rogers, Florencia; Coso, Omar Adrian; Piwien Pilipuk, Graciela; Rudland, Philip S.; Jimenez de Asua, Luis Adan Felipe Leukemia inhibitory factor (LIF) and oncostatin M (OSM) induce DNA synthesis in Swiss 3T3 cells through common signaling mechanism(s), whereas other related cytokines such as interleukin-6 and ciliary neurotrophic factor do not cause this response. Induction of DNA replication by LIF or prostaglandin F 2α (PGF 2α) occurs, in part, through different signaling events. LIF and OSM specifically trigger STAT1 cytoplasmic to nuclear translocation, whereas PGF 2α fails to do so. However, LIF and PGF 2α can trigger increases in ERK1/2 activity, which are required for their mitogenic responses because U0126, a MEK1/2 inhibitor, prevents both ERK1/2 activation and induction of DNA synthesis by LIF or PGF 2α treatment. PGF 2α induces cyclin D expression and full phosphorylation of retinoblastoma protein. In contrast, LIF fails to promote increases in cyclin D mRNA/protein levels; consequently, LIF induces DNA synthesis without promoting full phosphorylation of retinoblastoma protein (Rb). However, both LIF and PGF 2α increase cyclin E expression. Furthermore, LIF mitogenic action does not involve protein kinase C (PKC) activation, because a PKC inhibitor does not block this effect. In contrast, PKC activity is required for PGF 2α mitogenic action. More importantly, the synergistic effect between LIF and PGF 2α to promote S phase entry is independent of PKC activation. These results show fundamental differences between LIF and PGF 2α-dependent mechanism(s) that induce cellular entry into S phase. These findings are critical in understanding how LIF and other related cytokine-regulated events participate in normal cell cycle control and may also provide clues to unravel crucial processes underlying cancerous cell division.

El poblamiento inicial del sector austral de las Sierras Pampeanas de Argentina desde la ecología del paisaje Laguens, Andres Gustavo Se presenta un modelo sobre el poblamiento inicial y expansión de poblaciones del sector austral de las Sierras Pampeanas (Córdoba y San Luis) desde la ecología del paisaje. Se consideran las estrategias de movimiento poblacional, la estructura del paisaje, la definición de espacios de habitat y la dispersión de poblaciones hasta el Holoceno medio. Se analizan datos de sitios cazadores recolectores del límite Pleistoceno-Holoceno, hallazgos de posibles asociaciones con megafauna y datos bioantropológicos. Se postula un poblamiento por corredores ambientales de menor costo, desde las llanuras del Este, con posterior definición de distintos contornos de habitat y ajustes tecnológicos.; It is presented a model on the early peopling and expansion of human populations at the southern cone of the Sierras Pampeanas (Cordoba and San Luis) from a landscape ecology perspective. They are considered the strategies of population movements, the structure of the landscape, the definition of spaces of habitat and the dispersion of populations until the middle Holocene. Hunter-gatherers sites at the Pleistocene-Holoceno boundary are analyzed, as well as possible associations with megafauna and bioanthropological data It is advanced a peopling through environmental corridors of lower cost from the plains of the East, with subsequent definition of different habitat contours and technological adjustments.

Threshold resummation for high-transverse-momentum Higgs production at the LHC de Florian, Daniel Enrique; Kulesza, Anna; Vogelsang, Werner We study the resummation of large logarithmic QCD corrections for the process pp → H + X when the Higgs boson H is produced at high transverse momentum. The corrections arise near the threshold for partonic reaction and originate from soft gluon emission. We perform the all-order resummation at next-to-leading logarithmic accuracy and match the resummed result with the next-to-leading order perturbative predictions. The effect of resummation on the Higgs transverse momentum distribution at the LHC is discussed. © SISSA 2006.

La sociedad en movimiento: Expresiones culturales, sociales y deportivas (Siglo XX) Roldan, Diego Pablo Este volumen rastrea las historias de las ciudades de Rosario y de Santa Fe desde la efervescencia patriótica del Centenario hasta los primeros años de la década de 1980. Reconstruye algunos puntos relevantes de la historia de la sociedad, la cultura (en sentido amplio) y las prácticas deportivas registradas durante el período en la provincia de Santa Fe. Los festejos del Centenario (1910), la crisis desatada por la Primera Guerra Mundial, las prácticas y espacios orientados a civilizar y nacionalizar a las masas son objeto de una observación que se despliega sobre el tiro al blanco, los carnavales, el fútbol, los balnearios, las bibliotecas populares, las asociaciones vecinales, los círculos católicos de obreros, etc. Analiza las vanguardias artísticas durante la entreguerras, la experiencia peronista (1945-55), y los planes reguladores de Rosario y Santa Fe. El epilogo se concentra en los avatares del mundial de fútbol que la dictadura organizó en 1978 y que tuvo como subsede el estadio de Rosario Central.

La invención del consumo Fernandez, Sandra Rita Específicamente a posteriori de la crisis de 1913 y de la Primera Guerra aparece una ola de reactivación publicitaria, que va a fundar su desarrollo en el diseño gráfico de la publicidad y la estructura del mensaje tendiente a “domesticar” discursivamente tanto en palabras como en imágenes al público santafesino. La constitución de un público consumidor fue un proceso que llevó décadas. En realidad es difícil poder hablar de uno sólo, es más pertinente pensar en varios públicos, pero interrelacionados en función de sus gustos y posibilidades de consumo. Un sector con un poder adquisitivo alto tenía no sólo un abanico de posibilidades dentro de un segmento de consumo, sino una mayor injerencia dentro de varios nichos de productos. Por el contrario un público de escasos recursos o alejado de los vigorosos centros urbanos tenía mucha más concentrada su capacidad de demanda. La publicidad convocaba al público fundamentalmente urbano, por ello fue mucho más importante el impacto que esta tuvo sobre el público consumidor en ciudades como Rosario y Santa Fe. Esta batería de anuncios se anudaba con la variada gama de locales comerciales que dispuestos en el centro y los barrios acercaban a la sociedad los bienes comercializaban. Las poblaciones más pequeñas de la provincia muy ligadas al ámbito rural disponían de las almacenes de ramos generales. En estos lugares el progresivo avance de la sociedad de consumo permitió que surgieran comercios dedicados a rubros específicos, pero las almacenes de ramos generales, mantuvieron hasta muy entrado el siglo XX, su preponderancia comercial, incorporando ellas también toda la estrategia publicitaria de las grandes firmas nacionales. La descripción de este proceso dentro del espacio santafesino durante fines del siglo XIX y comienzos del siglo XX es el objetivo de este capítulo.

Excepción y paradigma de la década infame 1930-1943 Videla, Oscar Ruben El desarrollo histórico de la provincia de Santa Fe ha estado marcado profundamente por las vicisitudes de la vida nacional pero, particularmente en la coyuntura de los años treinta, largas cadenas de rupturas y continuidades nos permiten afirmar que la provincia era al mismo tiempo excepción y paradigma de aquellos procesos más generales. En poco más de una década la provincia se ve profundamente sacudida, por una parte los efectos de una crisis que ataca el corazón de su estructura productiva, por otra parte por una lenta pero persistente transformación de su estructura regional que redefinirá sus actividades agrarias y abrirá paso a un desarrollo industrial con destino de expansión, pero también se conmoverá por los vaivenes que lo llevan del liberalismo reformista de la gestión demoprogresista al predominio (fraude mediante) de un liberalismo conservador, representado en el radicalismo concordancista, de tintes tradicionalistas en lo ideológico pero moderadamente innovadores en la gestión del estado provincial.  En este sentido, para lograr una comprensión al mismo tiempo general y particular de este periodo de la historia provincial el artículo pretende analizar y caracterizar la realidad santafesina desde una perspectiva que articule las diversas escalas de análisis (nacional, provincial y local) con los distintos niveles de análisis de la misma.

El grupo Bunge y la política económica del primer peronismo, 1943-1952 Belini, Claudio Fabian Este trabajo analiza la influencia política e ideológica que el grupo de discípulos de Alejandro Bunge tuvo en la definición de la política económica del primer peronismo. Se sostiene que su postura favorable a la industrialización en los debates de la entreguerra y el influjo que el catolicismo social ejerció en sus miembros le permitió al grupo ejercer influencia sobre la dictadura militar de 1943. El artículo estudia el papel del grupo en la Secretaría de Industria, la elaboración del primer régimen de promoción industrial y los debates económicos de la inmediata posguerra. Se argumenta que el grupo Bunge desempeñó un rol decisivo en la orientación de la política industrial peronista, moldeando sus características básicas y brindando al régimen de Perón los argumentos que la justificaban. A propósito de ello, el trabajo discute la interpretación que otorga excesivo énfasis a factores políticos y sociales, como el enfrentamiento de Perón con los Estados Unidos y las demandas del movimiento obrero, en la orientación que tomó la política industrial peronista.; This paper analyzes the political and ideological influence that the group of disciples of Alejandro Bunge exerted over the definition of the economic policies during the first Peronist administration. It argues that the group's support for industrialization during the interwar period as well as the pressure exerted by social Catholicism upon its members allowed the group to manipulate the 1943 military government. Moreover, this article examines the role of the group in the Industry Secretariat, the formation of the first programof industrialpromotion,and the economic discussions held during the postwar period. It argues that the Bunge group played a decisive role in the orientation of Peronist industrial policies, shapingits basic characteristics, and justifying the policies. In this sense, this paper questions the argument that overly emphasizes the importance of political and social factors that oriented Peronist industrial policies, such as Peron's confrontation with the United States and the demands of the labor movement.

Calidad editorial y visibilidad de las revistas: La experiencia de Latindex Aguirre, Marcela; Cetto, Ana María; Córdoba, Saray; Flores, Ana Maria; Román, Adelaida Durante el Primer Taller sobre Publicaciones Científicas en América Latina, celebrado en Guadalajara, México, en 1994, se puso de manifiesto la falta de un sistema de información propio para las revistas científicas que se producen en América Latina y el Caribe. No fue aquella la primera vez que se expresaba la necesidad de contar con un sistema de tal naturaleza. En dicha ocasión, sin embargo, la preocupación tuvo eco en el seno de la UNAM, México, y condujo a la formulación de un proyecto para un sistema regional de información que habría de recoger el universo completo de publicaciones científicas seriadas, en todas las áreas del conocimiento y sin discriminación por idioma o lugar de publicación. Hacia fines de 1995 se tenía una primera versión del proyecto, al cual se dio el nombre de Latindex, Índice Latinoamericano de Publicaciones Científicas Seriadas. Se planteó desde un principio que, al no estar centralizado en una determinada institución o país, el proyecto basaría su fortaleza en el trabajo compartido y en la cercanía a las fuentes que generan o distribuyen datos sobre dichas publicaciones...

Antes y después: Marco de referencia del viaje de James Weddell 1822-1824 Piana, Ernesto Luis La historia de la marca más austral de Weddell está ampliamente divulgada. Su imagen de capitán lobero subsiste muy difundida. Pero la implicancia que el viaje de Weddell tuvo en relación con las exploraciones en las islas del Atlántico Sur, el archipiélago fueguino y la Isla de Tierra del Fuego, más las referencias a sus habitantes, los nómades canoeros, merecen ser conocidas y valoradas. Sin embargo, por tratarse de un libro de viaje, se requiere un marco para el lector que ubique a Weddell en sus circunstancias temporales y espaciales y explicite el valor de este texto Este trabajo presenta una biografía sucinta de él y los datos pertinentes de su contramaestre Brisbane, la importancia y desarrollo de las industrias peletera y de utilización de grasas de los lobos marinos, en esa época, la significación de haber alcanzado la latitud más austral y la duración de esta marca, cómo cambió la apreciación de Tierra del Fuego entre los navegantes a partir de sus descubrimientos y otros temas que valorizan el escrito y clarifican al lector. En particular se hace hincapié en la relación de J Weddell con los Yámana y la importancia que tiene su registro.