Role of polymorphisms 919A>G and 2039A>G of FSH receptor (FSHR) gene in premature ovarian failure (POF) development Sundblad, Victoria; Chiauzzi, Violeta Alicia; Andreone, Luz; Campo, Stella Maris; Charreau, Eduardo Hernan; Dain, Liliana Beatriz Although the impact of polymorphisms 919A>G and 2039A>G of FSHR gene in normal ovarian function is almost clear, in Premature Ovarian Failure (POF) it still remains elusive. To analyse the putative association of these polymorphisms with POF development, 97 POF patients and 72 women over 40 years of age with normal menstrual record were genotyped for 919A>G and 2039A>G variants. No association was found between genotype GG of each polymorphism and the risk of POF. Nevertheless, ten POF patients and only one control presented the less common combinations 919G-2039A and 919A-2039G (p<0.05). In addition, the frequency of primary amenorrhoea and the occurrence of familial POF were significantly increased among patients with 919GG-2039GG genotype. In 45 normally menstruating women, no significant differences were found among different FSHR genotypes in FSH, E2, Inhibin A and Inhibin B levels. In conclusion, FSHR polymorphism genotypes were not associated either to the risk of POF or to serum hormone levels of control women. However, 919GG-2039GG genotype might be associated to relatively more severe symptoms of POF. On the other hand, the differences found between controls and patients in the prevalence of the cross haplotypes, may suggest that these rare allelic variants might possibly influence POF development.

Histamine receptors and cancer pharmacology Medina, Vanina Araceli; Rivera, Elena S. Considerable evidence has been collected indicating that histamine can modulate proliferation of different normal and malignant cells. High histamine biosynthesis and content together with histamine receptors have been reported in different human neoplasias including melanoma, colon and breast cancer, as well as in experimental tumours in which histamine has been postulated to behave as an important paracrine and autocrine regulator of proliferation. The discovery of the human histamine H(4) receptor in different tissues has contributed to our understanding of histamine role in numerous physiological and pathological conditions revealing novel functions for histamine and opening new perspectives in histamine pharmacology research. In the present review we aimed to briefly summarize current knowledge on histamine and histamine receptor involvement in cancer before focusing on some recent evidence supporting the novel role of histamine H(4) receptor in cancer progression representing a promising molecular target and avenue for cancer drug development.

Phenolic compounds from Pterocaulon alopecuroides Alarcón, Silvia Rosana; Pacciaroni, Adriana del Valle; Peñaloza, Lidia; Uriburu Monasterio, Maria Laura; Boemo, Analía; Sosa, Virginia Estela Aerial parts of Pterocaulon alopecuroides (Lam.) DC. (Asteraceae), were collected at the flowering stage in December 2003 in Salta, Argentina. The identification was carried out by Ing. Julio Tolaba. A voucher specimen (n° 3399) is on deposit at the Museo de la Facultad de Ciencias Naturales, Universidad Nacional de Salta, Salta, Argentina.

The symmetric Radon-Nikodým property for tensor norms Carando, Daniel Germán; Galicer, Daniel Eric We introduce the symmetric-Radon-Nikodým property (sRN pr operty) for finitely generated s-tensor norms β of order n and prove a Lewis type theorem for s-tensor norms with this property. As a consequence, if β is a projective s-tensor norm with the sRN prop- erty, then for every Asplund space E , the canonical map e ⊗ n,s β E ′ → e ⊗ n,s β ′ E ′ is a metric surjection. This can be rephrased as the isometric isomorph ism Q min ( E ) = Q ( E ) for certain polynomial ideal Q . We also relate the sRN property of an s-tensor norm with the A splund or Radon-Nikodým properties of different tensor products. S imilar results for full tensor products are also given. As an application, results concern ing the ideal of n -homogeneous extendible polynomials are obtained, as well as a new proof o f the well known isometric isomorphism between nuclear and integral polynomials on As plund spaces.

Algunas aclaraciones acerca del articulo “Linajes parentales amerindios en poblaciones del norte de Córdoba” (García A, Demarchi DA, Rev. Arg. Antrop. Biol. 8(1):57-71, 2006) Demarchi, Dario; García, Angelina En un número anterior de esta revista se publicó el artículo "Linajes parentales amerindios en poblaciones del norte de Córdoba" (García y Demarchi, 2006). En ese estudio se investigó la composición genética de una muestra de habitantes "criollos" de dos poblaciones del norte de Córdoba, a través del análisis de los marcadores del ADN mitocondrial que determinan los 4 principales linajes maternos amerindios y el marcador M3, del cromosoma Y, diagnóstico de linaje paterno amerindio. Se determinó la proporción de los linajes (haplogrupos) amerindios que sobreviven en esas localidades, se puso a prueba la existencia de  posibles variaciones significativas en la distribución de linajes entre ambas muestras y, por último, se establecieron similitudes con otros pueblos originarios del Cono Sur en la distribución de linajes maternos nativos. En el presente número, los lectores de la RAAB encontrarán una nota que se propone descalificar nuestro estudio a través de una serie de críticas. No es nuestro objetivo responder puntualmente a cada una de ellas sino más bien echar luz sobre algunas dudas que puedan surgir en los lectores a partir de las mismas.

The effect of the hydrocarbon-water interface structure on the behavior of an emulsion stabilized with dodecanephosphonic acid Verdinelli, Valeria; Messina, Paula Verónica; Schulz, Eduardo Nicolás; Salinas, Daniel Ricardo; Vuano, Bruno Mario; Schulz, Pablo Carlos We studied the phase transition of petroleum ether/water/n-dodecanephosphonic acid (DPA) from W/O to W/O/W emulsion when the neutralization degree (nd) of dodecanephosphonic acid (DPA) with NaOH was changed. We concluded that a phase transition from W/O emulsion to W/O/W emulsion occurs when nd≈0.47 due to a change in the structure of the polar layer at the oil/water interface from a tightly hydrogen-bonded layer to a less compact layer formed by -PO3H2 and -PO3H- groups in favor of an inversion. The W/O/W emulsion is probably caused by a partition of acid molecules in the water droplets interface inside the oil droplets, and monosodium phosphonate molecules at the external interface of oil droplets.

The unexpected diet of breeding Imperial Shags (Phalacrocorax atriceps) at the Nahuel Huapi Lake, Patagonia: implications on population trends? Casaux, Ricardo Jorge; Bertolin, María Lila; Tartara, Maria Alejandra; Alarcón, Pablo Angel Eduardo; Porro, Gerardo The Imperial Shag Phalacrocorax atriceps is widely distributed along the coast of South America and in Malvinas/Falkland Islands(Orta 1992). This shag is marine in most its range and forages predominantly on fish, although invertebrates were frequently reported as present in the diet(e.g., Punta etal. 2003, Ferrari et al. 2004, Bulgarella et al.2008)Reynolds (1934) reported the presence of the Imperial Shag breeding at Yehuin Lake,Tierra del Fuego, and later on Pereyra (1945, quoted in Navas 1970), Chebez & Gómez (1988) and Rasmussen et al. (1992) reported the existence of the only other three populations of this shag breeding in freshwater environments,the Nahuel Huapi (NHL),Fagnano, and Vintter lakes, respectively. Despite the potential interest in studying these populations, few studies provided information on the biology of this shag species. Although not globally threatened, the Imperial Shag at NHL is locally endangered and between the summers of 1990 (Rasmussen et.al. 1993) and 2005 (Pastore et al. 2005)the total number of individuals decreased in 68%. Thus,the aim of this study is provide the first information on the diet of the Imperial Shag breeding at NHL to improve the knowledge of the foraging behavior of this species as well as to explore the linkage between diet composition and the reported declining trend of this population.

La ciénaga afgana y la responsabilidad estadounidense Cuadro, Mariela El artículo analiza la actuación de las fuerzas de seguridad estadounidenses en Afganistán. A tal fin, se detiene en las distintas tácticas en juego en las esferas de poder en Washington. Detecta, entonces, un retorno al tratamiento hostil a los civiles afganos, produciéndose, entonces, una espiral que, se concluye, amenaza con transformarse en una guerra infinita.

Alto Chorrillo: otra alternativa para instalar una antena para ondas milimétricas y submilimétricas en Argentina Bareilles, Federico Ariel; Morras, Ricardo; Hauscarriaga, Fernando Pablo; Olalde, Juan Carlos; Guarrera, Leonardo; Arnal, Edmundo Marcelo We present preliminary data of atmospheric opacity at 210 GHz obtained between July 2009 and August 2010 at "Alto Chorrillo", a place near San Antonio de los Cobres, in the province of Salta at 4800 m above sea level. The data is compared with those obtained in the previous campaign con- ducted in Tolar Grande (also in Salta). Alto Chorrillo has a baseline larger than 130 km (E-W) regarding to ALMA, making it a good candidate to in- stall a radio astronomy facility that can operate in VLBI mode with ALMA.

Ultra Fast Response to Light Radiation in SnO2 Microrods Perillo, Patricia Maria; Rodriguez, Daniel Fabian; Rinaldi, Carlos Alberto; Lamagna, Alberto SnO2 microrods exhibited an ultra-fast photo-response when light led 402-940 nm was switched on and off. SnO2 microrods films were prepared with SnCl4 as the starting material. We found that increasing light radiation flux decreases the resistance. The effect of radiation on the film will be discussed as function of chemiabsorbed oxygen.

Ciudad letrada y dictadura: los espacios en Nocturno de Chile de Roberto Bolaño Aguilar, Paula O artigo explora a construção dos espaços urbanos no Chile da ultima ditadura no romance de Roberto Bolaño Nocturno de Chile. O analise indaga o tratamento das cumplicidades, responsabilidades e os medos no interior da „cidade letrada‟ que o autor expressa como reflexo de uma sociedade marcada pelo horror do poder ditatorial.; The article explores the representation of urban spaces in Chilean last dictatorship in Roberto Bolaño‟s Nocturno de Chile. The analysis studies complicity, responsibility and fear in „the lettered city‟ as a reflection of a society marked by the horrors of dictatorial power.

Photographs and silhouettes: visual politics in the human rights movement of Argentina Longoni, Ana Entre las distintas estrategias creativas desplegadas por las Madres de Plaza de Mayo y otros familiares dentro del movimiento de derechos humanos durante la última dictadura argentina (1976-1983), pueden reconocerse y contrastarse dos grandes matrices de representación visual de los desaparecidos: las fotos y las siluetas. Ambas surgieron (casi) en paralelo y tienen una larga historia, sin buscar oponerlas, sino más bien distinguir los sentidos desplegados en los distintos recursos y modos de producción simbólica que pudieron generar, así como reponer las coordenadas históricas en las que han devenido en signos que -en Argentina e incluso fuera de ella- remiten inequívocamente a los desaparecidos e incluso llegan a reconocerse como un lenguaje simbólico universal.

Intrasexual competition at work: Sex differences in the jealousy-evoking effect of rival characteristics in work settings Buunk, Abraham P.; aan't Goor, Joel; Castro Solano, Alejandro Sex differences in jealousy-evoking rival characteristics in the relationship with a supervisor at work were examined in a community sample of 188 individuals from Argentina. Among men, the rivals' social dominance and communal attributes evoked the most jealousy, followed by physical dominance. Among women, the rival's communal attributes evoked the most jealousy, followed by social dominance and physical attractiveness. For men physical dominance of the rival and for women physical attractiveness of the rival evoked relatively more jealousy, especially among those high in intrasexual competition and confronted with a same-sex supervisor. When confronted with an opposite-sex supervisor, social comparison orientation was associated with more jealousy in response to rivals with communal attributes. © The Author(s).

La individuación: una perspectiva sobre la cuestión del hombre Ferreyra, Diego Julián Este artículo se propone plantear la pregunta por el hombre fuera de los marcos clásicos que intentaron pensarlo en términos de género y de especies, o en términos de forma y materia. Para ello recurriremos al concepto de individuación tal como este fue desarrollado por Gilbert Simondon y retomado por Gilles Deleuze. Este concepto permite pensar al hombre a partir de las diferencias que lo constituyen y no a partir de su identidad en la representación. En lugar de partir de aquello que se pretende explicar (los individuos constituidos), se trata de comprender el proceso de su génesis a partir sus condiciones ontológicas: un fondo de puras diferencias que, lejos de disolver las formas, las produce.

Eutrophication and macroalgal blooms in temperate and tropical coastal waters: Nutrient enrichment experiments with Ulva spp. Teichberg, Mirta; Fox, Sophia E.; Olsen, Ylva S.; Valiela, Ivan; Martinetto, Paulina Maria del Rosario; Iribarne, Oscar Osvaldo; Muto, Elizabeti Yuriko; Petti, Monica A.V.; Corbisier, Thaïs N.; Soto-Jiménez, Martín; Páez-Osuna, Federico; Castro, Paula; Freitas, Helena; Zitelli, Andreina; Cardinaletti, Massimo; Tagliapietra, Davide Receiving coastal waters and estuaries are among the most nutrient-enriched environments on earth, and one of the symptoms of the resulting eutrophication is the proliferation of opportunistic, fast-growing marine seaweeds. Here, we used a widespread macroalga often involved in blooms, Ulva spp., to investigate how supply of nitrogen (N) and phosphorus (P), the two main potential growth-limiting nutrients, influence macroalgal growth in temperate and tropical coastal waters ranging from low- to high-nutrient supplies. We carried out N and P enrichment field experiments on Ulva spp. in seven coastal systems, with one of these systems represented by three different subestuaries, for a total of nine sites. We showed that rate of growth of Ulva spp. was directly correlated to annual dissolved inorganic nitrogen (DIN) concentrations, where growth increased with increasing DIN concentration. Internal N pools of macroalgal fronds were also linked to increased DIN supply, and algal growth rates were tightly coupled to these internal N pools. The increases in DIN appeared to be related to greater inputs of wastewater to these coastal waters as indicated by high δ15N signatures of the algae as DIN increased. N and P enrichment experiments showed that rate of macroalgal growth was controlled by supply of DIN where ambient DIN concentrations were low, and by P where DIN concentrations were higher, regardless of latitude or geographic setting. These results suggest that understanding the basis for macroalgal blooms, and management of these harmful phenomena, will require information as to nutrient sources, and actions to reduce supply of N and P in coastal waters concerned.

Effect of di(2-ethylhexyl) phthalate (DEHP) on lipolysis and lipoprotein lipase activities in adipose tissue of rats Martinelli, Marcela Inés; Mocchiutti, Norberto Oscar; Bernal, Claudio Adrian The di(2-ethylhexyl) phthalate (DEHP) is an ubiquitous environmental chemical with detrimental health effects. The present work was designed to asses some potential mechanisms by which DEHP causes, among others, a reduced body fat retention. Since this effect could be related to an alteration of adipocyte triacylglycerol (TG) metabolism, we evaluated the effects of dietary DEHP in adipose tissues upon (1) the number and size of fat cells; (2) the basal and stimulated lipolysis and (3) the lipoprotein lipase (LPL) activity. Groups of male Wistar rats were fed for 21 days a control diet alone (control group) or the same control diet supplemented with 2% (w/w) of DEHP (DEHP group). The LPL activity of DEHP-fed rats was increased in lumbar and epididymal adipose tissues. These rats had significantly reduced weight in epididymal and lumbar tissues, together with reduced size of epididymal adipocytes. These alterations do not seem to be associated with higher lipid mobility because neither basal lipolysis nor in vitro stimulated lipolysis by noradrenaline (NA) showed to be modified by DEHP. Based on these results, we concluded that the adipose tissue size reduction induced by DEHP intake is not due to changes in lipolysis nor to a decreased LPL activity. More research is needed to achieve a comprehensive understanding of the potential mechanisms by which DEHP causes, among others, a reduced body fat retention.

Selectividad isotópica en la disociación multifotónica infrarroja de SiF4; Isotopic selectivity in the infrared multiple-photon dissociation of SiF4 Alcaraz, A. N.; Codnia, Jorge; Azcárate, María Laura Se estudió la selectividad isotópica de la DMFIR de SiF4 con distintas líneas de emisión de la banda de 9,4 μm de un láser de CO2 TEA. Se irradiaron mezclas de SiF4 e H2 con la línea 9P(36), cuasi-resonante con la frecuencia vibracional del modo ν3 de 28SiF4, y con líneas corridas hacia el rojo y el azul con respecto de ésta. La fracción disociada por pulso se determinó por espectrometría FTIR siguiendo la desaparición de la molécula precursora, SiF4, y la aparición del producto, SiF3H. Los factores de enriquecimiento 29,30α en el reactivo (SiF4) y 29,30β en el producto (SiF3H) se determinaron mediante espectrometría de masas.; The isotopic selectivity of the IRMPD of SiF4 following irradiation with different emission lines of the 9.4 μm band of a TEA CO2 laser has been studied. The 9P(36) line is quasi-resonant with the vibrational frequency of the ν3 mode of 28SiF4. Mixtures of SiF4 and H2 have been irradiated with the rotational lines 9P(32) - 9P(42). The fraction of molecules dissociated per pulse was determined by FTIR spectrometry following the disappearance of the working molecule, SiF4, and the appearance of the product, SiF3H. The enrichment factors both in the reactant (SiF4), 29,30α, and in the product (SiF3H), 29,30β, have been determined by mass spectrometry

PCR múltiple para la detección de los genes sea, seb, sec, sed y see de Staphylococcus aureus: Caracterización de aislamientos de origen alimentario; Multiplex PCR for the detection of sea, seb, sec, sed and see genes of Staphylococcus aureus: Characterization of isolates from food Manfredi, E.A.; Leotta, Gerardo Anibal; Rivas, M. La presencia de Staphylococcus aureus en los alimentos representa un riesgo potencial para la salud pública; sus enterotoxinas son el principal factor de virulencia. La detección de las enterotoxinas de S. aureus puede realizarse por ELISA, aunque sólo es posible detectar el pool de enterotoxinas SEA, SEB, SEC, SED y SEE. Los objetivos del presente trabajo fueron optimizar dos técnicas de PCR múltiple para la detección de los genes sea, seb, sec, sed y see de S. aureus y caracterizar un conjunto de 115 aislamientos de Staphylococcus spp. asociados a intoxicaciones alimentarias provenientes de diferentes provincias de Argentina. La caracterización se realizó por pruebas bioquímicas, ELISA y PCR. Sesenta y ocho aislamientos (59,1%) fueron positivos por ELISA, mientras que 61 (53%) fueron positivos por PCR. De los aislamientos positivos por PCR, 34 (55,7%) portaron el gen sea, 9 (14,8%) el gen seb, 5 (8,1%) el gen see, 4 (6,5%) el gen sec, 6 (9,9%) los genes sea y seb, 2 (3,3%) los genes sea y sec, y 1 (1,7%) los genes sea y sed. Este es el primer estudio de caracterización genotípica de aislamientos de S. aureus asociados con brotes de intoxicación alimentaria registrados en distintas provincias argentinas.; The presence of Staphylococcus aureus in food represents a potential risk to public health, being its enterotoxins the major virulence factor. Enterotoxin detection can be determined by ELISA, but only for the pool of enterotoxins SEA, SEB, SEC, SED and SEE. The main aims of this study were to optimize two PCR techniques for detection of S. aureus sea, seb, sec, sed and see, and to characterize Staphylococcus spp. isolates associated with food intoxication. Two PCR techniques were optimized and 115 Staphylococcus spp. isolates from Ciudad Autónoma de Buenos Aires, and Buenos Aires, Córdoba, and Neuquén provinces were characterized. The characterization was performed by biochemical tests, ELISA and PCR. Sixty-eight isolates (59.1%) were positive by ELISA, while 61 (53%) were positive by PCR. Out of the positive PCR isolates, 34 (55.7%) carried the sea gene, 9 (14.8%) the seb gene, 5 (8.1%) the see gene, 4 (6.5%) the sec gene, 6 (9.9%) were positive for sea and seb genes, 2 (3.3%) for sea and sec genes, and 1 (1.7%) for sea and sed genes. This is the first study of genotypic characterization of S. aureus isolates associated with food intoxication from different provinces of Argentina.

Human papillomavirus DNA and oncogene alterations in colorectal tumors Perez, Luis Orlando; Barbisan, Gisela; Ottino, Anabel; Pianzola, Horacio; Golijow, Carlos Daniel The aim of the present study is to determine the presence and molecular integrity of high-risk HPV types in colorectal adenocarcinomas and to assess whether viral DNA is related to common proto-oncogene alterations, such as k-ras mutations and c-myc gene amplification, in colorectal cancer. Seventy-five colorectal adenocarcinomas were screened for HPV infection using nested-PCR (MY09/11-GP5+/6+). HPV typing was performed by type-specific PCR for HPV 16 and HPV 18 DNA. Unidentified samples were subsequently sequenced to determine the viral genotype. The physical status of HPV was determined by a nested PCR approach for type-specific E2 sequences. C-myc amplification was assessed by co-amplification with β-globin as control locus, and mutation in k-ras codons 12 and 13 by ARMS-PCR. Overall, HPV was detected in thirty-three colorectal specimens (44%). HPV 16 was the prevalent type (16/75), followed by HPV 18 (15/75), HPV 31 (1/75) and HPV 66 (1/75). E2 disruption was detected in 56.3% of HPV 16 and in 40% of HPV 18 positive tumors. C-myc amplification was detected in 29.4% of cases, while k-ras mutations in 30.7%. There was no significant trend for HPV infection in tumors harboring either k-ras or c-myc alterations. This study demonstrates HPV DNA and viral integration in colorectal tumors, suggesting a potential role of this virus in colorectal carcinogenesis. There was no concurrence, however, of k-ras and c-myc activation with viral infection.

La valoración del patrimonio desaparecido, un acercamiento a la cultura local desde el relato de los actores: El caso de la Estación Cerri en el partido de Bahía Blanca (Provincia de Buenos Aires); A valorização do patrimônio desaparecido, uma aproximação com a cultura local a partir do relato dos atores: O caso da Estação Cerri no distrito de Bahía Blanca (Província de Buenos Aires); Valorization of lost patrimony, an approach to local culture from the narratives of social actors: The case of the ‘Cerri Railway Station’ in the district of Bahía Blanca (Province of Buenos Aires) Kraser, María Belén; Lorda, María Amalia Desde la visión de la Geografía Social y Cultural del espacio como identidad, de lugar vivido, los espacios se cargan de sentimientos que sólo pueden ser comprendidos desde el relato, la historia y las imágenes de los propios actores locales involucrados. Ambas reivindican la compresión frente a la explicación y valoran la emoción por encima del objeto material de los fenómenos sociales (Comerci, 2005). La identidad de los espacios implica el reconocimiento del patrimonio local, que involucra al conjunto de manifestaciones materiales e inmateriales que una sociedad carga de valor y significado conformando su cultura local. Tanto el patrimonio visible como el invisible, sustentado como parte constituyente del imaginario social y alimentado por historias e imágenes, merecen especial atención, puesto que al evaluar un patrimonio se adopta también un fundamento ético con el cual se sustenta una posición responsable (Lorda, 1998). En algunas oportunidades el reconocimiento de un componente tangible local como parte integrante del patrimonio de una comunidad, deviene con la desaparición del mismo, puesto que la valoración y sentimiento de pertenencia se evidencian cuando por distintos motivos ya no están. Este es el caso de la primigenia estación férrea de la localidad de General Daniel Cerri, poblado situado a 15km de la ciudad de Bahía Blanca en el partido homónimo, al sudoeste de la provincia de Buenos Aires. El valor histórico cultural de la misma en el área radica en su vinculación al desarrollo del poblado en tiempos pasados y en relación directa con el devenir económico y social del país desde fi nes de siglo XIX; aspecto que hoy debe ser abordado mediante la línea de análisis del patrimonio desaparecido. La metodología empleada de carácter cualitativo permite el predominio del trabajo de campo en ente escrito, mediante la recopilación de información por medio de observaciones y entrevistas semiestructuradas a informantes claves. La técnica de biografías individuales desde la mirada microsocial en conexión con la temporalidad espacial se convierte en pilar esencial, enmarcada a su vez en base a la recopilación, análisis e interpretación de bibliografía pertinente que brindan el encuadre teórico.; Sob o ponto de vista da Geografi a Social e Cultural do espaço como identidade, de lugar vivido, os espaços se carregam de sentimentos que só podem ser compreendidos pelo relato, a história e as imagens dos próprios atores locais envolvidos. Ambas reivindicam a compreensão frente à explicação e valorizam a emoção em detrimento do objeto material dos fenômenos sociais (Comerci, 2005). A identidade dos espaços implica o reconhecimento do patrimônio local, que envolve o conjunto de manifestações materiais e imateriais que uma sociedade carrega de valor e signifi cado conformando sua cultura local. Tanto o patrimônio visível como o invisível, sustentado como parte constituinte do imaginário social e alimentado por histórias e imagens, merecem especial atenção, posto que ao avaliar um patrimônio se adote também um fundamento ético com o qual se sustenta uma posição responsável (Lorda, 1998). Em algumas oportunidades o reconhecimento de um componente tangível local como parte integrante do patrimônio de uma comunidade, surge com o desaparecimento do mesmo, posto que a valorização e sentimento de pertencimento se evidenciam quando por distintos motivos já não estão lá. Este é o caso da primeira estação férrea da localidade de General Daniel Cerri, povoado situado a 15km da cidade de Bahía Blanca no distrito homônimo, ao sudoeste da província de Buenos Aires. O valor histórico e cultural da mesma na área se radica em sua vinculação ao desenvolvimento do povoado em tempos passados e em relação direta com o devir econômico e social do país desde fi ns do século XIX; aspecto que hoje deve ser abordado mediante a linha de análise do patrimônio desaparecido. A metodologia empregada de caráter qualitativo permite o predomínio do trabalho de campo, mediante a recopilação de informação por meio de observações e entrevistas semi-estruturadas a informantes chave. A técnica de biografi as individuais sob o olhar microsocial em conexão com a temporalidade espacial se converte em pilar essencial, enquadrada por sua vez com base na recopilação, análise e interpretação de bibliografi a pertinente que brindam o quadro teórico.; From the vision of Social and Cultural Geography, of space as identity, as lived space, spaces are loaded with feelings which can olny be understood from the narratives, stories and images of local actors. Both disciplines remark the importance of understanding over explaining and value emotion over the material object of the social phenomena (Comerci, 2005). The identity of spaces implies the recognition of the local patrimony that invloves material and immaterial manifestations that a society loads with value and meaning to conform its local culture. The visible and invisible patrimony considered as part of the social imaginary and built on the basis of stories and images, deserve special attention because, to evaluate patrimony, implies adopting an ethical basis from a responsible position (Lorda, 1998). On occassions, the recognition of a local and tangible component as part of the patrimony in a comunity begins with the disappearance of that component, since its valorization and sense of belonging become evident when it no longer exists or has been lost. This is the case of the original railway station of the town of General Cerri, located 15 km from the city of Bahía Blanca, to the Southwest of the province of Buenos Aires. The historical and cultural value of this station in the area is related to the development of the town in the past and to the socio-economical evolution of the country during the XIX century, a fact that today needs to be approached from the perspective of lost patrimony. The qualitative methodology used allows for the predominance of fi eld work turned into written versions and data collection through observation and semiestructural interviews to key informants. The technique of individual biographies analysed from a microsocial perspective in conection with the spatial temporality is essential and at the same time becomes the basis for the collection, analysis and interpretation of the appropriate bibliography which provides the theoretical framework.