Ciencia y Tecnología
Archivos trasnfeministas: Una genealogía común
Martínez Prado, Natalia; Ferrucci, Verónica; Morales, María Gabriela; Perrote, Noelia; Alfonzo, Luisina Nahilin
Del 21 al 23 de septiembre se desarrolló en la Universidad Nacional de Córdoba el 6° Congreso de Género y Sociedad convocado a partir de la premisa Desplazar los centros: cuerpos, territorios y saberes de Nuestramérica. En esta edición, desde la Comisión Cultura organizamos una instalación titulada Archivos Itinerantes Transfeministas. Una muestra cordobesa, que trazó una genealogía de intervenciones públicas sobre sexualidad, género y cuerpos en y desde nuestros territorios. En este escrito colectivo compartimos lo que consideramos como las perlitas de la muestra.
Análisis comparativo de modelos digitales del terreno obtenidos con LiDAR aéreo y structure from motion: Aplicación en estudios del paisaje en el sitio inka El Shincal de Quimivil (Noroeste argentino)
Análisis comparativo de modelos digitales del terreno obtenidos con LiDAR aéreo y structure from motion: Aplicación en estudios del paisaje en el sitio inka El Shincal de Quimivil (Noroeste argentino); Comparative analysis of digital terrain models obtained with aerial LiDAR and Structure from Motion: Application in landscape studies at the Inka site El Shincal de Quimivil, Northwest Argentina
Moralejo, Reinaldo Andres; López, Luciano; Gobbo, Juan Diego; del Cogliano, Daniel Hector
En este trabajo se comparan los resultados de un relevamiento con LiDAR aéreo ystructure from motionen el sitioinkaEl Shincal de Quimivil. Este sitio se localiza en la provincia de Catamarca y es considera-do uno de los centros políticos, administrativos y ceremoniales incaicos más emblemáticos del Noroesteargentino. Para realizar esta comparación y explorar las potencialidades de ambas técnicas, se realizaroncálculos estadísticos de las diferencias de alturas y se llevaron a cabo análisis espaciales de visibilidad ymovilidad humana, entendidos respectivamente como la representación visual de un espacio y como lacapacidad de moverse a través de él. Las mayores diferencias se registraron en zonas con vegetación densay altas pendientes. Naturalmente, la referencia es el Modelo Digital del Terreno determinado con LiDAR,que no es afectado por esas circunstancias y tiene calidad de pocos centímetros en todas las componen-tes. En suelo desnudo, ambos modelos son comparables. Por lo tanto, una de las claves para la elecciónde estas técnicas es decidir el uso que le daremos a cada una ellas de acuerdo con el tipo de terreno, laescala del trabajo y el error que estamos dispuestos a aceptar.; This paper compares the results of a survey with aerial LiDAR and Structure from Motion at the Inka site El Shincal de Quimivil. This site is located in the province of Catamarca and is considered one of the most emblematic Inka political, administrative and ceremonial centres in the Northwest Argentina. In order to compare and explore the potential of both techniques, statistical calculations of height differences were made and spatial analysis of visibility and human mobility, understood respectively as the visual representation of a space and the ability to move through it, were carried out. The greatest differences were registered in areas with dense vegetation and high slopes. Naturally, the reference is the Digital Terrain Model determined with LiDAR, which is not affected by these circumstances and has a quality of a few centimetres in all components. On bare ground, both models are comparable. Therefore, one of the keys to choose between these techniques is to decide how to use each of them according to the type of terrain, the scale of work, and acceptable error.
Algunas aproximaciones al uso de la alegoría en los relatos artúricos: Un recorrido por diversos textos, territorios y modos de significar
Algunas aproximaciones al uso de la alegoría en los relatos artúricos: Un recorrido por diversos textos, territorios y modos de significar; Some Approaches to the Use of Allegory in Arthurian Narrative: A Journey through Various Texts, Territories, and Ways of Meaning
Abeledo, Manuel
La alegoría, entendida en su sentido retórico estricto como un procedimiento que produce la significación a través de una estructura de metáforas, es uno de los dispositivos retóricos más frecuentes en la Edad Media; sin embargo, casi no aparece en la literatura artúrica del período. el presente trabajo busca, a través del análisis de sus escasas apariciones, y de una serie de sistemas de equivalencias que se apoyan, aunque con fines diversos, en la forma alegórica, entender los procesos hermenéuticos que rigen estos pasajes, y los modos en que se articula la participación de los personajes y del lector en la administración informativa; The allegory, understood in its strict rhetorical sense as a procedure that produces signification through a structure of metaphors, is one of the most frequent rhetorical devices in the Middle Ages; nevertheless, it’s nearly absent in the Arthurian literature of the period. This work, through the analysis of the rare occasions in which allegory appears and of a series of equivalence systems that are based on the allegorical form (although with different purposes), aims to understand the hermeneutic procedures that rule those fragments, and the ways in which the participation of characters and of the reader in the administration of information is articulated.
Covalent coupling of Spike’s receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2
Covalent coupling of Spike’s receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2
Berguer, Paula Mercedes; Blaustein, Matías; Bredeston, Luis María; Craig, Patricio Oliver; D'alessio, Cecilia; Elias, Fernanda; Farré, Paola C.; Fernández, Natalia Brenda; Gentili, Hernan Gustavo; Gándola, Yamila Belén; Gasulla, Javier; Gudesblat, Gustavo Eduardo; Herrera, Maria Georgina; Ibañez, Lorena Itatí; Idrovo Hidalgo, Tommy; Nadra, Alejandro Daniel; Noseda, Diego Gabriel; Pavan, Carlos Humberto; Pavan, Maria Florencia; Pignataro, María Florencia; Roman, Ernesto Andres; Ruberto, Lucas Adolfo Mauro; Rubinstein, Natalia; Sanchez Sanchez, Maria Victoria; Santos, Javier; Wetzler, Diana Elena; Zelada, Alicia Mercedes
The receptor binding domain (RBD) of the Spike protein from SARS-CoV-2 is a promising candidate to develop effective COVID-19 vaccines since it can induce potent neutralizing antibodies. We have previously reported the highly efficient production of RBD in Pichia pastoris, which is structurally similar to the same protein produced in mammalian HEK-293T cells. In this work we designed an RBD multimer with the purpose of increasing its immunogenicity. We produced multimeric particles by a transpeptidation reaction between RBD expressed in P. pastoris and Lumazine Synthase from Brucella abortus (BLS), which is a highly immunogenic and very stable decameric 170 kDa protein. Such particles were used to vaccinate mice with two doses 30 days apart. When the particles ratio of RBD to BLS units was high (6–7 RBD molecules per BLS decamer in average), the humoral immune response was significantly higher than that elicited by RBD alone or by RBD-BLS particles with a lower RBD to BLS ratio (1–2 RBD molecules per BLS decamer). Remarkably, multimeric particles with a high number of RBD copies elicited a high titer of neutralizing IgGs. These results indicate that multimeric particles composed of RBD covalent coupled to BLS possess an advantageous architecture for antigen presentation to the immune system, and therefore enhancing RBD immunogenicity. Thus, multimeric RBD-BLS particles are promising candidates for a protein-based vaccine.
Genes, exposures, and interactions on preterm birth risk: an exploratory study in an Argentine population
Genes, exposures, and interactions on preterm birth risk: an exploratory study in an Argentine population
Elias, Dario Ezequiel; Santos, María Rita; Campaña, Hebe; Poletta, Fernando Adrián; Heisecke Peralta, Silvina Lidia; Gili, Juan Antonio; Ratowiecki, Julia; Cosentino, Viviana Raquel; Uranga, Rocio; Rojas Málaga, Diana; Brinckmann Oliveira Netto, Alice; Brusius Facchin, Ana Carolina; Saleme, César; Rittler, Mónica; Krupitzki, Hugo Bernardo; López Camelo, Jorge Santiago; Gimenez, Lucas Gabriel
Preterm birth (PTB) is the main condition related to perinatal morbimortality worldwide. The aim of this study was to identify associations of spontaneous PTB with genetic variants, exposures, and interactions between and within them. We carried out a retrospective case–control study including parental sociodemographic and obstetric data, and fetal genetic variants. We sequenced the coding and flanking regions of five candidate genes from the placental blood cord of 69 preterm newborns and 61 at term newborns. We identify the characteristics with the greatest predictive power of PTB using penalized regressions, in which we include exposures (E), genetic variants (G), and two-way interactions. Few prenatal visits (< 5) was the main predictor of PTB from 26 G, 35 E, 299 G × G, 564 E × E, and 875 G × E evaluated terms. Within the fetal genetic characteristics, we observed associations of rs4845397 (KCNN3, allele T) variant; G × G interaction between rs12621551 (COL4A3, allele T) and rs73993878 (COL4A3, allele A), which showed sensitivity to anemia; and G × G interaction between rs11680670 (COL4A3, allele T) and rs2074351 (PON1, allele A), which showed sensitivity to vaginal discharge. The results of this exploratory study suggest that social disparities and metabolic pathways linked to uterine relaxation, inflammation/infections, and collagen metabolism would be involved in PTB etiology. Future studies with a larger sample size are necessary to confirm these findings and to analyze a greater number of exposures.
Síntesis y caracterización de SnO2 nanocristalino, dopado, aplicado en sensores de gases de alta sensibilidad para detectar ppm de H2S (g) en aire
Síntesis y caracterización de SnO2 nanocristalino, dopado, aplicado en sensores de gases de alta sensibilidad para detectar ppm de H2S (g) en aire
Poiasina, Mariana Paola; Bianchetti, Mario Fidel; Heredia, Eduardo; Cánepa. Horacio; Walsöe de Reca, N. E.
En este trabajo, se consideran varios factores que aumentan la sensibilidad de un sensor de tipo resistivo, de alta precisión, útil para detectar de (10 a 15) ppm de H2S (g) en aire. Se acepta que el dopado del material sensor (SnO2) aumenta la sensibilidad del dispositivo. Se probaron varios dopantes llegando a la conclusión de que el CuO era el más conveniente. Existen en la bibliografía numerosos trabajos que presentan diferentes técnicas para dopar el material del sensor pero, en este trabajo, se utilizó una técnica propia de dopado, desarrollada en el DEINSO, en la cual el dopante se encuentra distribuido en la red cristalina del SnO2 en forma homogénea. Se propuso dopar el SnO2 nanocristalino, con distintas concentraciones de CuO (1%peso, 5%peso y 6%peso) para elegir la más adecuada que resultó de 5%peso de CuO. Con estas condiciones, se fabricó un sensor más sensible y se estudiaron otros factores para aumentar la sensibilidad. El 5%pesoCuO-SnO2 fue depositado en forma de películas delgadas for mando un sistema multicapas (que emplea de tres a seis capas o láminas delgadas superpuestas). Se caracterizó el material con distintas técnicas como XRD, SEM-EDS y GISAXS mediante las cuales se determinó el tamaño promedio de cristalita, el espesor, la cr istalinidad, la composición química y la porosidad de las películas. Con el sensor construido se detectó una concentración de (10-15) ppm de H2S (g) en aire, a una temperatura de operación de 140ºC, lo que permitió resolver la solicitud de un sensor de seguridad ambiental para la planta de cracking de una importante Institución Argentina (YTEC). Si bien este tema no se incluye en este trabajo, se informa que el logro de un aumento de la sensibilidad de un sensor de este tipo permite detectar concentraciones de (4 a 5) ppm de H2S en aire a una To de ~ 45ºC, permitiendo construir un sensor de uso médico, para detectar muy bajas concentraciones (menores de 5ppm) de H2S(g) que se encuentran en halitosis de enfermedades hepáticas.; Several factors are considered in this article, which increase the sensitivity of a high precision resistive-type sensor, useful for detecting from (10 to 15) ppm of H2S (g) in air. It is accepted that the doping of the sensor material (SnO2) increases the sensitivity of the device. Various dopants were tested, concluding that CuO was the most suitable. There are numerous reports in the bibliography that show different techniques for doping the sensor material, but in this work, a proprietary doping technique was used, developed at DEINSO, in which the dopant is homogeneously distributed in the crystalline network of SnO2. It was proposed to dope the nanocrystalline SnO2 with different concentrations of CuO (1%wt, 5%wt, and 6%wt) to choose the most suitable one that resulted in 5%wt CuO. With these conditions, a more sensitive sensor was carried out, and other factors were studied to increase the sensitivity. The 5%wt CuO-SnO2 was deposited in the form of thin films forming a multilayer system (using three to six superimposed layers or thin sheets). The material was characterized with different techniques such as XRD, SEM-EDS, and GISAXS through which the average crystallite size, thickness, crystallinity, chemical composition, and porosity of the films were determined. With the built sensor, a concentration of (10-15) ppm of H2S (g) was detected in air, at an operating temperature of 140ºC, which allowed solving the request for an environmental safety sensor for the cracking plant of an important Argentine Institution (YTEC). Although this subject is not included in this article, it is orth reporting that achieving increased sensitivity of such a sensor allows to detect concentrations of (4 to 5) ppm H2S in air at a To of ~ 45ºC, just to build a sensor for medical use, to detect very low concentrations (less than 5 ppm) of H2S (g) found in halitosis of liver diseases.
On post-breakdown initialization for ignition models
On post-breakdown initialization for ignition models
Aranciaga, Joaquín; Lopez, Ezequiel Jose; Nigro, Norberto Marcelo
An accurate evaluation of the processes taking place from the spark onset until the flame self-propagates in spark ignition internal combustion engines would be very beneficial. It would provide engine designers with more reliable criteria, and this in turn would help lower harmful emissions and achieve improved energy utilization. In order to be computationally affordable, combustion codes contain models which simplify specific tasks. Particularly, the ignition process is very demanding in terms of computational cost, so ignition models are normally resorted to. Their accuracy heavily relies on the knowledge of the physics of the process and their simplifying hypothesis. Currently widely used low-dimensional models are perceived to oversimplify some essential features, perhaps being the most important the role of plasma hydrodynamics, which eventually defines the kernel shape. In this work the effect some fundamental parameters have on the whole process, such as electrode and spark gap dimensions, amount of discharged energy and initial chamber pressure and temperature, is simulated. A qualitative and quantitative analysis allows the assessment of a recently proposed low-dimensional thermodynamic model devised for fast discharges, and to establish its range of validity. Some modifications to this model are introduced in order to improve its predictive capabilities and to extend its range of applicability. Additionally, the effect of a further arc or glow discharge and the influence of electrode configuration asymmetry are simulated, providing a methodology to treat both cases.
Alfonso X de Castilla y Don Denis de Portugal en el espejo: Trovar y dejar de trovar
Alfonso X de Castilla y Don Denis de Portugal en el espejo: Trovar y dejar de trovar
del Rio, María Gimena
Resulta un lugar común en los estudios sobre lírica trovadoresca acercarse a las biografías de los trovadores con una mirada contemporánea o trazando paralelos entre los compositores. El caso más destacable es quizás el de los reyes-trovadores Alfonso X y Don Denis. Los reyes de Castilla y Portugal, además de compartir lazos de sangre y un lugar de privilegio en la corte, son los autores mejor representados en las tradiciones manuscritas de la gallego-portuguesa: Alfonso X se destaca como el trovador de la Virgen en las Cantigas de Santa María, y Don Denis es el trovador profano con más textos conservados en los cancioneros coloccianos. El trabajo explora los problemas que suscita la lectura del pasado con los ojos del presente y se circunscribe específicamente a un género que nace y se desarrolla en la oralidad, y al que lo recorre un alto grado de interdiscursividad. Por ende, invita a pensar los procedimientos compositivos de intertextualidad (e intermelodicidad) dentro de la interdiscursividad de la composición lírica, más allá de las hipótesis incomprobables sobre circulación material de textos o de roles y modelos a seguir.; It is a commonplace in troubadour lyric studies to approach the troubadours’ biographies with a contemporary perspective or drawing parallels between composers. The most notable case is perhaps the one of the king troubadours Alfonso X and Don Denis. The kings of Castile and Portugal share blood ties and a place of privilege at the court, and are also the best represented troubadours of the GalicianPortuguese manuscript tradition: Alfonso X stands out as the troubadour of the Virgin in the Cantigas de Santa María and Don Denis is the profane troubadour with the highest quantity of texts preserved in the Coloccian songbooks. This work explores the problems raised when we read the past with contemporary eyes and its reflections are specifically circumscribed to the Galician-Portuguese lyric poetry, an oral genre that is characterized by a high degree of interdiscursiveness. Therefore, it understands the compositional procedures of intertextuality (and intermelodicity) within interdiscursiveness, and beyond the many times unverifiable hypotheses on circulation of texts or role models.
Palabra femenina y discurso religioso medieval en Otas de Roma
Palabra femenina y discurso religioso medieval en Otas de Roma; Feminine word and medieval religious speech in Otas de Roma
Zubillaga, Carina Alejandra
En el presente trabajo, se analiza el discurso de Florencia de Roma, la heroína de "Otas de Roma", en relación con el de las protagonistas santas de las hagiografías previas del Ms. h-I-13 de la Biblioteca de San Lorenzo de El Escorial. Las oraciones y súplicas que jalonan el desarrollo de la historia y testimonian su avance dan cuenta de una identidad femenina que se conforma mediante la subordinación de lo terrenal a lo divino y de lo individual a lo colectivo, en consonancia con las historias de reinas acusadas a las que pertenece y con la figura política de la infanta y la problemáticade la sucesión imperial.; In the present work, the discourse of Florence of Rome, the heroine of Otas de Roma, is analyzed in relation to the holy protagonists of the previous hagiographies of Escorial MS. h-I-13. The prayers and supplications that mark the development of the story and testify to its progress reveal a feminine identity that is shaped by the subordination of the earthly to the divine and of the individual to the collective, in line with the stories of the accused queens to which it belongs and with the political figure of the infanta and the problems of imperial succession.
Flash point and refractive index measurements of diesel and biodiesel, and their binary blends with n-butanol and n-pentanol
Flash point and refractive index measurements of diesel and biodiesel, and their binary blends with n-butanol and n-pentanol
Figueroa Semorile, Nicolás; Alviso, Dario; Romano, Silvia Daniela
The use of n-butanol (BU) and n-pentanol (PE) as biofuels has gained much attention in recent years. As they have high oxygen content, they could be a future option to be used in Diesel engines for mixing with diesel fuel (DF), biodiesel (BD) and their blends, resulting in lower pollutant emissions. Flash point (FP) is used to regulate fuel handling and storage conditions. Refractive index (RI) has been used for the characterization of BD/DF blends and the estimation of light refraction in several combustion-related studies. Several works focusing on the use of BU and PE in blends with either DF or BD in Diesel engines have been recently carried out. However, less information is available in the literature concerning the measurements of properties such as the FP and the RI of these blends. This paper presents experimental measurements of FP and RI (from 15 to 40 ∘C) for BD and DF, and their binary blends with BU and PE in the full range of composition. The RI and FP of the studied BD and DF, as well as their blends with BU and PE, are also estimated using regression equations as a function of their composition.
Global patterns of herbicide resistance evolution in Amaranthus spp.: an analysis comparing species, cropping regions and herbicides
Global patterns of herbicide resistance evolution in Amaranthus spp.: an analysis comparing species, cropping regions and herbicides
Yanniccari, Marcos Ezequiel; Gaines, Todd; Scursoni, Julio Alejandro; De Prado, Rafael; Vila Aiub, Martin Miguel
Herbicide resistance in weeds is an evolutionary process. Although there is a great global diversity of weeds, independent origins of herbicide resistance evolution have been shown to converge into similar molecular and physiological resistance mechanisms in geographically distant weed populations. Amaranthus species have shown an extraordinary ability to evolve herbicide resistance and invade new environments at a global scale, which represents an opportunity for identifying adaptive evolutionary patterns. The most frequent cases of herbicide-resistant Amaranthus species have been identified in North America, where A. hybridus, A. palmeri, A. tuberculatus and A. retroflexus comprise more than 90% of them. Meanwhile, A. retroflexus, A. hybridus and A. palmeri have been the most reported species in South America. Around 70% of the cases of herbicide-resistant Amaranthus species have been identified in global soybean and corn crops. The higher fecundity and adaptability of plants to a broad range of environments would make populations more likely to persist and be selected for herbicide resistance. Co-evolution of multiple herbicide resistance mechanisms at the plant and/or population level is evident in weed species. For Amaranthus spp., resistance cases highlight evolutionary responses to herbicide use with clear patterns of selection for multiple herbicide resistance in particular regions and spread to new areas within and between global cropping systems. Seed-mediated gene flow is an important component to the spread of herbicide resistant Amaranthus spp. populations. Reduction of the intensity of herbicide selection by combining diverse and integrated weed control practices should be a common goal in weed management programs.
Participatory Ethics in Bakhtin: Pandemic and Pansemic
Participatory Ethics in Bakhtin: Pandemic and Pansemic; Ética participativa em Bakhtin: Pandemia e pansemia
Arán, Pampa; Gómez Ponce, Fernando Ariel
The philosophical project that Bakhtin conceived at the beginning of the 20th century aims to find a moral philosophy that modifies the performance of man in daily life and in culture. The date 1924 on which its writing is presumed would indicate the direction that Bakhtinian thought was taking, proposing an utopian cultural transformation in a time marked by enormous political tensions, and the social construction of a real subject, whose moral responsibility historically situated would turn into a modeof participatory action. Since that historical moment, a century has passed, and today it may be opportune to confront it with our present, in a planet governed by the capitalist economy with its population living a pandemic of great proportions. Far fromestablishing a comparison with that ethic project, we will offer some notes and images that encourage reflection on a philosophy that we do not believe we can cover in its complexity.; O projeto filosófico concebido por Bakhtin no início do século XX visava fundar uma filosofia moral que modificasse a atuação do homem na vida cotidiana e na cultura. A data em que se presume que o texto foi escrito [1924?] indicaria o rumo que tomava esse pensamento e o modo como ele propunha, quase utopicamente, a transformação cultural em um momento marcado por enormes tensões políticas e a construção social de um sujeito concreto, cuja responsabilidade moral estivesse historicamente situada e se convertesse em um modo de ação participativa. Desde aquele momento histórico, um século se passou, e hoje pode ser oportuno confrontá-lo com o nosso presente, em um planeta governado pela economia capitalista e uma população sofrendo com uma pandemia de grandes proporções. Longe da pretensão de estabelecer uma comparação, oferecemos alguns apontamentos e imagens que estimulam a reflexão sobre essa filosofia ética, a qual não acreditamos poder abarcar em sua complexidade
Impact of genetic ancestry on the distribution of interferon-λ4 rs12979860 polymorphism in a global population of Buenos Aires, Argentina
Impact of genetic ancestry on the distribution of interferon-λ4 rs12979860 polymorphism in a global population of Buenos Aires, Argentina; Impacto de la ancestría genética en la distribución del polimorfismo de interferón-λ4 rs12979860 en una población global de Buenos Aires, Argentina
Mansilla, Florencia Celeste; Avena, Sergio Alejandro; Dejean, Cristina Beatriz; Turco, Cecilia Soledad; Capozzo, Alejandra Victoria
Human interferon-λ4 is a cytokine involved in early stages of antiviral responses. Strikingly, some allelic variants with diminished antiviral activity reduce the susceptibility to viral infections, thus they would have suffered a positive selection pressure throughout the evolutionary history of the genus Homo. An intronic variant within the IFNλ4 locus (rs12979860, T˃C) emerged as one of the main gene determinants of the response to HCV and other viruses. The rs12979860-C allele has a differential frequency in African, European and Native American populations, though South American data are scarce. Here we characterize for the first time the distribution of rs12979860 genotypes in a sample of the global population of Buenos Aires, Argentina, assessing its association with European, Native American and African parental components. The rs12979860 genotypes were determined by PCR-RFLP in DNA samples from donors of a blood banks of Buenos Aires (n=96), whose genetic individual ancestry (European, African or Native American) had been previously determined using molecular markers. The distribution of rs12979860-CC, CT and TT was 29.17%, 50.0% and 20.83%, respectively. A significant increase in the frequency of CC among donors with a strong European contribution and a greater impact of the Native American component among donors carrying the T allele were observed. Native American and European components were associated to the rs12979860 distribution in a sample of the global population of Buenos Aires, while no differences were directly attributable to the African ancestry. Considering interferon´s key role in antiviral responses, our results may contribute to both bioanthropological and immunogenetic studies associated with infectious diseases.; El interferón-λ4 humano es una citoquina involucrada en la respuesta antiviral. Algunas variantes alélicas con menor actividad antiviral, paradójicamente, reducen la susceptibilidad a infecciones virales, por lo que habrían sufrido una presión de selección positiva en la historia evolutiva del gיnero Homo. Una variante dentro del locus de IFNλ4 (rs12979860, T˃C), con distribución diferencial en poblaciones africanas, europeas y nativas americanas, surgió como uno de los principales determinantes genéticos de la respuesta al HCV y otros virus. Aquí caracterizamos por primera vez la distribución de los genotipos de rs12979860 en una muestra de la población cosmopolita de Buenos Aires, Argentina, evaluando el impacto de su ancesrtría. Se determinaron diferentes genotipos de rs12979860 por PCR-RFLP en muestras de ADN de donantes de bancos de sangre de Buenos Aires (n=96), cuya ancestría individual había sido previamente determinada mediante diferentes marcadores moleculares. La distribución global de rs12979860-CC, CT y TT fue 29,17%; 50,0% y 20,83%, respectivamente. Se observó un aumento significativo de la frecuencia del genotipo CC entre individuos con fuerte aporte europeo y un mayor impacto del componente nativo-americano entre portadores del alelo T. Los componentes nativo-americano y europeo se asociaron a la distribución rs12979860 en una muestra poblacional global de Buenos Aires, mientras que no se vieron diferencias directamente asociadas a la ancestría africana. Considerando el papel clave del interferón en la respuesta antiviral, nuestros resultados pueden contribuir a estudios con un enfoque bioantropológico así como a estudios inmunogenéticos asociados a enfermedades infecciosas.
Hacia una eco/ontología política del desarrollo: Territorio y relacionalidad desde América Latina
Hacia una eco/ontología política del desarrollo: Territorio y relacionalidad desde América Latina; Towards a political eco/ontology of development: Territory and relationality from América Latina
Borrastero, Matías Alejandro
En el presente artículo recupero algunos elementos claves de la deconstrucción del desarrollo con el objetivo de avanzar en una comprensión crítica de las relaciones entre sociedad y naturaleza, desde una perspectiva decolonial. En ese marco, propongo una aproximación al desarrollo en tanto dispositivo moderno/colonial, destacando algunas contribuciones sumamente fructíferas para la construcción de un enfoque interdisciplinario que integre las dimensiones eco y ontológica en la comprensión de los conflictos y resistencias socioambientales. En función de ello, me detengo en tres ejes de reflexión que considero centrales en esta indagación: primeramente, en torno de la construcción de la territorialidad estatal-moderna y la colonialidad de la naturaleza, raíces históricas que permiten comprender al largo proceso de conquista y colonización latinoamericana como condición de posibilidad para el despliegue del moderno dispositivo del desarrollo. Y, de manera posterior, en torno de la relacionalidad como elemento clave para una perspectiva que integre y complemente ecología y ontología política. El trabajo tiene por objetivo ofrecer una suerte de coordenadas epistémico-políticas para orientar un camino de indagación crítica en torno de la intersección entre naturaleza, cultura, territorio y desarrollo, en el marco de la invitación a construir cartografías críticas del(os) territorio(s). A su vez, interesa destacar los principales aportes del enfoque del posdesarrollo, en tanto marco de comprensión centrado en las resistencias, adaptaciones y subversiones al desarrollo. Como corolario de esta indagación, presento algunos elementos que, desde mi lectura, resultan hoy desafíos en la construcción de las ciencias sociales latinoamericanas. Nuevos -y no tan nuevos- interrogantes que interpelan nuestro quehacer académico y nuestro crítico cotidiano.; In this article I recover some key elements of the deconstruction of development with the objective of advancing in a critical understanding of the relations between society and nature, from a decolonial perspective. In this context, I propose an approach to development as a modern/colonial dispositive, recovering some extremely fruitful contributions for the construction of an interdisciplinary approach which integrates an eco and ontological dimensions in the understanding of socio-environmental conflicts and resistance. Based on this, I inquire on three issues that I consider central to this research: firstly, around the construction of modern-state territoriality and the coloniality of nature, historical roots that allow us to understand the long process of conquest and Latin American colonization as a condition of possibility for the deployment of the modern device of development. And, later, around relationality as a key element for a perspective that integrates a political ecology and political ontology. This work aims to offer a kind of epistemic and political key elementos to guide a critical inquiry around the intersection between nature, culture, territory and development, in the framework of an invitation to build critical cartographies of the territory(s).
Revisión de aplicaciones de técnicas de monitoreo no intrusivo de cargas en redes eléctricas inteligentes
Revisión de aplicaciones de técnicas de monitoreo no intrusivo de cargas en redes eléctricas inteligentes; Review of non-intrusive load monitoring techniques applications in smart grids
Donato, Patricio Gabriel; Hernández, Álvaro; Funes, Marcos Alan; Carugati, Ignacio; Nieto, Rubén; Ureña, Jesús
Las redes eléctricas inteligentes están transformando la relación de los usuarios con la electricidad de diferentes maneras. En este artículo se resumen algunas potenciales aplicaciones que se desarrollarán en los próximos años bajo este marco conceptual, las cuales tienen como denominador común el uso de técnicas de monitoreo no intrusivo de cargas. Estas técnicas permiten desagregar consumos a partir de mediciones puntuales en ciertos lugares de la red eléctrica, sin necesidad de monitorear dispositivos en forma individual. Algunas de estas nuevas funcionalidades tienen especial relevancia en las redes eléctricas de los países en vías de desarrollo, las cuales presentan retos complejos y necesitan una modernización, mientras que otras tienen su motivación en demandas específicas de países desarrollados. En todos los casos, el uso de técnicas de monitoreo no intrusivo de cargas abre nuevos campos de investigación y desarrollo tecnológico aplicado que van desde aspectos técnicos de las redes eléctricas hasta cuestiones de índole social.; The Smart Grids concept is transforming the relationship of customers with the electricity in different ways. This paper provides a general overview of some potential applications to be developed under this conceptual framework, which have as a common denominator the use of non-intrusive load monitoring techniques. These techniques make it possible to disaggregate consumption based on specific measurements at certain locations in the electricity grid, without implement measurement points in each device to be monitored. Some of these new functionalities are particularly relevant for electricity grids in developing countries, which present complex challenges and need modernisation, while others are motivated by specific demands in developed countries. In all cases, the use of non-intrusive load monitoring techniques opens up new fields of applied research and technological development ranging from power grids to social issues.
Resistencias en escenarios de colonización: Análisis comparado de los movimientos de mujeres Mapuche y beduinas del Néguev
Resistencias en escenarios de colonización: Análisis comparado de los movimientos de mujeres Mapuche y beduinas del Néguev; Resistances in colonization scenarios: Comparative analysis of the Mapuche and Bedouin of the Negev women’s movements
Silvestri, María Agostina
El presente trabajo procurará presentar y desarrollar un binomio comparado entre las estrategias de lucha y resistencia de las mujeres indígenas, particularmente de las mujeres mapuche, y de las mujeres palestinas, particularmente de las beduinas del Néguev. Se atenderá a exponer las principales condiciones sociales, históricas y políticas que delinean en cada caso la participación de las mujeres en la resistencia a la colonización-ocupación y en la (re)organización comunal. Se abordarán particularmente las estrategias tendientes a la recuperación y/o visibilización de las identidades mapuche y beduina, y la lucha por la recuperación de los territorios y por la liberación nacional / libre determinación de los pueblos. A estos fines, se realizará un análisis hermenéutico de fuentes bibliográficas y audiovisuales.; This work will attempt to present and develop a comparative pairing between the strategies of struggle and resistance of indigenous women, particularly Mapuche women, and Palestinian women, particularly the Bedouin of the Nagev. The main social, historical, and political conditions that delineate in each case the participation of women in resistance to colonization-occupation and in community (re) organization will be addressed. Strategies aimed at the recovery and / or visibility of Mapuche and Bedouin identities, and the struggle for the recovery of the territories and for the national liberation / self-determination of the peoples, will be particularly addressed. For these purposes, a hermeneutical analysis of bibliographic and audiovisual sources will be carried out.
Evaluar la efectividad de la levadura de cerveza subproducto de la industria cervecera como bioestimulante en hidroponía
Evaluar la efectividad de la levadura de cerveza subproducto de la industria cervecera como bioestimulante en hidroponía; Evaluate the effectiveness of brewer’s yeast by-product of the brewing industry as a biostimulant in hydroponics; Avaliar a eficácia do subproduto de levedura de cerveja da indústria cervejeira como bioestimulante em hidroponia
Vazquez, Maria Magdalena; Quintana, Silvina; Medici, Sandra Karina; Gende, Liesel Brenda
Es conocida la capacidad de algunos microorganismos de estimular el crecimiento y desarrollo de las plantas. Sin embargo, el uso de levaduras de la industria cervecera como agentes promotores del crecimiento de plantas (PGPM, por sus siglas en inglés) ha sido brevemente estudiado. El objetivo de este trabajo fue caracterizar y analizar el uso de la levadura residual de la fabricación de cerveza artesanal en cultivos hidropónicos. Se evaluó el efecto de la adición de dicha levadura en el crecimiento y desarrollo de Arabidopsis thaliana, Eruca vesicaria y Lactuca sativa en almácigos y en sistemas hidropónicos. Se observó un aumento significativo en el largo de la raíz principal luego del tratamiento con las suspensiones de levadura en A. thaliana y E. vesicaria crecidas en almácigos (SN 4.28 ± 0.15, S05 7.30 ± 0.29; SN 39.68 ± 2.20, S05 57.37 ± 2.80, respectivamente). En sistemas hidropónicos de raíz flotante, la inoculación de levadura a la solución hidropónica incrementó un 30 % el área radicular de L. sativa en relación con el control. Se concluye que la inoculación de S. cerevisiae cepa J14 aislada del residuo de la elaboración de cerveza, sola o incorporada a la solución nutritiva de sistemas hidropónicos, podría ser una herramienta biotecnológica como bioestimulante y/o promotor del crecimiento vegetal.; The ability of some microorganisms to stimulate the growth and development of plants is known. However, the use of residual yeast from the artisanal brewing industry as plant growth promoting microorganisms (PGPM) has been briefly studied. The aim of this work was to characterize and analyze the use of residual yeast from the brewing industry in hydroponic vegetable crops. We evaluated the effects of yeast addition on plant growth of Eruca vesicaria, Arabidopsis thaliana y Lactuca sativa with this technique. A significant increase in the principal root length was observed after the treatment with the yeast suspensions in A. thaliana and E. vesicaria grown relative to the control (SN 4.28 ± 0.15, S05 7.30 ± 0.29; SN 39.68 ± 2.20, S05 57.37 ± 2.80, respectively). In floating hydroponic systems, yeast inoculation to the hydroponic solution increased the root area of L. sativa by 30 % in relation to the control. Our results confirm that Saccharomyces cerevisiae strain J14 from the brewing industry may confer benefits in hydroponics crops with positive effects on root growth. These results validate the potential application of S. cerevisiae strain J14 in plant cultivation in hydroponic as a biotechnological tool.; A capacidade de alguns microrganismos de estimular o crescimento e desenvolvimento de plantas é conhecida. No entanto, o uso de levedura residual da indústria cervejeira artesanal como agente promotor de crescimento vegetal (PGPM, por sua sigla em inglês) tem sido brevemente estudado. O objetivo deste trabalho foi caracterizar e analisar o uso de levedura residual da indústria cervejeira em hortaliças hidropônicas. Nós avaliamos os efeitos da adição de levedura no crescimento de plantas de Eruca vesicaria, Arabidopsis thaliana e Lactuca sativa com esta técnica. Um aumento significativo no comprimento da raiz principal e no número de raízes laterais foi observado após o tratamento com as suspensões de levedura em A. thaliana e E. vesicaria cultivadas em mudas (SN 4.28 ± 0.15, S05 7.30 ± 0.29; SN 39.68 ± 2.20, S05 57.37 ± 2.80, respectivamente). Em sistemas hidropônicos de raízes flutuantes, a inoculação de leveduras à solução hidropônica aumentou a área radicular de L. sativa em 30 % em relação ao controle. Nossos resultados confirmam que a estirpe J14 de Saccharomyces cerevisiae da indústria cervejeira pode prover benefícios em cultivos hidropônicos com efeitos positivos no crescimento radicular. Esses resultados validam a potencial aplicação da cepa J14 de S. cerevisiae no cultivo de plantas em hidroponia como ferramenta biotecnológica.
Biomedical treatment and divine assistance: complementary reproductive itineraries among catholic women users of assisted reproduction technology in Argentina
Biomedical treatment and divine assistance: complementary reproductive itineraries among catholic women users of assisted reproduction technology in Argentina
Olmos Alvarez, Ana Lucía; Johnson, Maria Cecilia
This paper explores how Catholic women in Argentina use assisted reproduction technologies (ARTs), and particularly the way in which they resort to biomedicine and religion as complementary sources of knowledge, support and assistance during reproductive treatments. It is concerned about the role of the Catholic religion in local reproductive itineraries, seeing that Catholicism has such significant social, political and cultural influence in the country. Drawing on a qualitative and ethnographic study of Catholic spaces of worship, a maternity hospital and in-depth interviews with former users from three metropolitan areas in Argentina, we examine how reproductive itineraries involve the users’ agency in building health resources from religion, with reference to biomedicine. The data reveal that women address religion as an affective, social and therapeutic recourse intertwined with biomedical power. These findings highlight the multiple and complex forms reproduction acquires in specific social, cultural and normative contexts, and contribute to discussing the complementarity between religion and biomedicine in health experiences.
Age-related Changes in Task Switching Costs in Middle Childhood
Age-related Changes in Task Switching Costs in Middle Childhood
Vernucci, Santiago; García Coni Bosch, Ana Virginia; Zamora, Eliana Vanesa; Gelpi Trudo, Rosario; Andrés, María Laura; Canet Juric, Lorena
Cognitive flexibility refers to the ability to rapidly and accurately switch between tasks. It is regarded as a core dimension of executive functions and has been reported to improve during childhood and into early adulthood. For its evaluation, the task-switching paradigm is widely used. Switching between tasks or response sets imposes a series of costs on performance (i.e., mixing costs, global switch costs, local switch costs). There is less evidence analyzing switching performance in children than in other age groups, and few studies have specifically analyzed switching costs only in school-age children. In the present study, we aimed to analyze age-related changes in task switching in children aged 9–12 years old. We considered year-to-year changes in performance, specifically in response time based mixing costs, global switch costs, and local switch costs. To do this, we used a task switching measure to evaluate 231 children in Argentina, aged 9–12 years (M age = 10.94, SD = 0.88) who were aggregated into four age groups (9, 10, 11, and 12 years old). Results show consistent mixing costs, global switch costs, and local switch costs at each age. However, we did not find age-related differences in the magnitude of such costs. These results suggest that both the ability to maintain and select between two tasks, and to switch from one response set to another could be considered relatively constant during this period.
Structural parameters of biofilm and bacterioplankton are better indicators of urbanization than photosynthetic functional parameters in low-order streams
Structural parameters of biofilm and bacterioplankton are better indicators of urbanization than photosynthetic functional parameters in low-order streams
Gorbarán, Rocío Soledad; Vilches, Carolina; Rodríguez Castro, María Carolina; Giorgi, Adonis David Nazareno; Torremorell, Ana María
The aim of this study was to assess urbanization effects on microbial communities from low-order streams. Artificial substrata were placed upstream (control) and downstream (urban) of the cities of the selected streams. Photosynthetic parameters derived from chlorophyll-a fluorescence were measured using a Pulse of Amplitude Modulated Fluorometer, and the bacterial biofilm and bacterioplankton were counted by microscopy after staining with 4′,6-diamidino-2-phenylindole. We found higher bacterial biofilm biomass together with higher concentration of nutrients in urban reaches. The biofilm total density of bacteria was negatively correlated with the humic acid concentration, while the bacterioplankton total density was positively correlated with soluble reactive phosphorus and nitrite concentration. Autotrophic Index reflected the predominance of heterotrophs in the three streams. The concentration of chlorophyll-a, the minimum fluorescence, and the other photosynthetic parameters showed variations between the streams. These would respond to environmental factors at local scale not included in this study and may be influenced by the low development of autotrophic biomass at least in two of the streams studied. The bacterial morphotypes Small rod, Large rod, and Vibrio shaped (large) allowed the differentiation of urban reaches and would be useful as indicators of urbanization effects in both biofilm and bacterioplankton of lowland streams.
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