Harmonic complex structures and special hermitian metrics on products of Sasakian manifolds Andrada, Adrián Marcelo; Tolcachier, Alejandro It is well known that the product of two Sasakian manifolds carries a 2-parameter family of Hermitian structures (J_(a,b), g_(a,b)). We show in this article that the complex structure J_(a,b) is harmonic with respect to g_(a,b) , i.e. it is a critical point of the Dirichlet energy functional. Furthermore, we also determine when these Hermitian structures are locally conformally Kähler, balanced, strong Kähler with torsion, Gauduchon or k-Gauduchon (k ≥ 2). Finally, we study the Bismut connection associated to (J_(a,b), g_(a,b)) and we provide formulas for the Bismut-Ricci tensor Ric^B and the Bismut-Ricci form ρ^B . We show that these tensors vanish if and only if each Sasakian factor is η-Einstein with appropriate constants and we also exhibit some examples fulfilling these conditions, thus providing new examples of Calabi-Yau with torsion manifolds.

Machine learning models predict the emergence of depression in Argentinean college students during periods of COVID-19 quarantine López Steinmetz, Lorena Cecilia; Sison, Margarita; Zhumagambetov, Rustam; Godoy, Juan Carlos; Haufe, Stefan Introduction: The COVID-19 pandemic has exacerbated mental health challenges, particularly depression among college students. Detecting at-risk students early is crucial but remains challenging, particularly in developing countries. Utilizing data-driven predictive models presents a viable solution to address this pressing need. Aims: 1) To develop and compare machine learning (ML) models for predicting depression in Argentinean students during the pandemic. 2) To assess the performance of classification and regression models using appropriate metrics. 3) To identify key features driving depression prediction. Methods: A longitudinal dataset (N = 1492 college students) captured T1 and T2 measurements during the Argentinean COVID-19 quarantine. ML models, including linear logistic regression classifiers/ridge regression (LogReg/RR), random forest classifiers/regressors, and support vector machines/regressors (SVM/SVR), are employed. Assessed features encompass depression and anxiety scores (at T1), mental disorder/suicidal behavior history, quarantine sub-period information, sex, and age. For classification, models’ performance on test data is evaluated using Area Under the Precision-Recall Curve (AUPRC), Area Under the Receiver Operating Characteristic curve, Balanced Accuracy, F1 score, and Brier loss. For regression, R-squared (R2), Mean Absolute Error, and Mean Squared Error are assessed. Univariate analyses are conducted to assess the predictive strength of each individual feature with respect to the target variable. The performance of multi- vs univariate models is compared using the mean AUPRC score for classifiers and the R2 score for regressors. Results: The highest performance is achieved by SVM and LogReg (e.g., AUPRC: 0.76, 95% CI: 0.69, 0.81) and SVR and RR models (e.g., R2 for SVR and RR: 0.56, 95% CI: 0.45, 0.64 and 0.45, 0.63, respectively). Univariate models, particularly LogReg and SVM using depression (AUPRC: 0.72, 95% CI: 0.64, 0.79) or anxiety scores (AUPRC: 0.71, 95% CI: 0.64, 0.78) and RR using depression scores (R2: 0.48, 95% CI: 0.39, 0.57) exhibit performance levels close to those of the multivariate models, which include all features. Discussion: These findings highlight the relevance of pre-existing depression and anxiety conditions in predicting depression during quarantine, underscoring their comorbidity. ML models, particularly SVM/SVR and LogReg/RR, demonstrate potential in the timely detection of at-risk students. However, further studies are needed before clinical implementation.

Zygosporium palaeogibbum sp. nov. (Xylariales, Ascomycota) associated with Cinnamomum Schaeff. (Lauraceae) leaves from the Siwalik (Middle Miocene) of eastern Himalaya Mahato, Sumana; Bianchinotti, Maria Virginia; Kundu, Sampa; Khan, Mahasin Ali Well-preserved remains of a mitosporic fungus were found on leaf cuticles of Cinnamomum sp. (Lauraceae) recovered from the lower Siwalik (Chunabati Formation; Middle Miocene) sedimentary stratum of Darjeeling foothills of eastern Himalaya. Based on the characteristic features (solitary vesicular conidiophores arising directly from a superfcial mycelium and strongly curved, darkly pigmented, ovoid to pyriform vesicles with 1–3 celled stalk cells), it is here proposed as a new fossilspecies, Zygosporium palaeogibbum sp. nov. The in situ evidence of Z. palaeogibbum in appreciable numbers on the host leaf cuticles suggests the probable existence of a host-specifc saprophytic relationship in the Darjeeling sub-Himalaya’s ancient warm humid tropical climate during the time of deposition. This conclusion on past climate is in agreement with published qualitative, quantitative, and palaeomycological climatic data obtained from the study of megafossil plant remains from the same fossil locality.

SolNet dataset: Descriptors obtained by Tomato Analyzer in a publicly available images dataset on the SolNetwork website A set of tomato fruit images publicly available was downloaded from SolNetwork. The images were analyzed with the Tomato Analyzer (version 2.0) which is a computer vision-based program that permits the semi-automated and objective measurement of 47 fruit shape, size, and colour descriptors obtained from the longitudinal and latitudinal section of tomato A total of 1424 images, representing 368 tomato accessions, and 41 morphological attributes, were analyzed. The dataset includes as well, four categorical shape features, one for each shape classification system available in tomato.

Revista fonoaudiológica, ¿un reflejo del desarrollo de la actividad científica disciplinar a lo largo de los años?; Fonoaudiológica journal, a reflection of the development of the disciplinary scientific activity over the years? Romero, Luciano Nicolás; Berra, Silvina del Valle; Rivadero, Luisina; Dame, Yasmin; Ramos Elizagaray, Libertad; Maggi, Ana Luz; Yordan, Martina; Valdez, VAnessa; Hinalaf, María de Los Angeles La Revista Fonoaudiológica es el principal órgano de difusión de la investigación disciplinar en Argentina. El objetivo fue describir las tendencias en las áreas profesionales en Fonoaudiología y la cantidad de artículos publicados por año en tres períodos de la Revista Fonoaudiológica. Se llevó a cabo un estudio descriptivo en el que se analizaron artículos publicados en tres períodos: 1956-1969 (P1) y 1970-1981 (P2) de números impresos; 2016-2023 (P3) de números digitalizados. Los artículos se consignaron según el año de publicación, volumen y número de la revista, título y área profesional fonoaudiológica. Se analizaron 269 artículos; 101 pertenecientes al P1, 98 al P2 y 70 al P3. Los resultados mostraron en promedio artículos publicados por volumen con cierta irregularidad en los tres períodos analizados; la mayor cantidad se observó en el P1 y la menor, en el P3. Con relación a las áreas de la Fonoaudiología, se observó disparidad en el predominio en los tres períodos, siendo Audición (27,7%) en el P1, Voz (23,5%) en el P2 y Fonoestomatología (28,6%) en el P3. Se reconocen intereses de divulgación de los productos de investigación científica internacional en una etapa inicial y de difusión de investigaciones locales en los últimos años. Este trabajo contribuye al análisis del desarrollo profesional en Fonoaudiología mediante una aproximación histórica a los artículos publicados en la revista y propone inquietudes para nuevas investigaciones que puedan ampliar el conocimiento desde diferentes perspectivas.; The Fonoaudiológica Journal is the main organism of diffusion on disciplinary research in Argentina. The aim was to describe the trends in the professional areas in speech, language and hearing sciences and the number of articles published per year in three periods of the Fonoaudiológica Journal. A descriptive study was carried out in which articles published in three periods were analyzed: 1956-1969 (P1) and 1970-1981 (P2) of printed issues; 2016-2023 (P3) of digitized issues. The articles were recorded according to the year of publication, volume and issue of the journal, t itle and speech, language and hearing sciences professional area. 269 articles were analyzed; 101 belonging to P1, 98 to P2 and 70 to P3. The results showed on average articles published by volume with some irregularity in the three periods analyzed; the highest amount was observed in P1 and the lowest in P3. In relation to the areas of speech, language and hearing sciences, a disparity was observed in the predominance in the three periods, hearing (27.7%) in P1, voice (23.5%) in P2 and phonoestomatology (28.6%) in P3. Interests are recognized in diffusion international scientific research products in an initial stage and diffusion local research in recent years. This study contributes to the analysis of professional development in speech, language and hearing sciences through a historical approach to the articles published in the journal and proposes concerns for new research that can expand knowledge from different perspectives.

Feocromocitoma y paraganglioma en un hospital pediátrico de Argentina: Serie de casos Deregibus, María I.; Pompozzi, Luis A.; Sanso, Elsa Gabriela El feocromocitoma y el paraganglioma son tumores neuroendocrinos secretores de catecolaminas. Los feocromocitomas se originan en la médula suprarrenal, mientras que los paragangliomas son extraadrenales. Se describe una serie de casos de niños con diagnóstico anatomopatológico de feocromocitoma o paraganglioma que consultaron en un hospital pediátrico de alta complejidad de Argentina. Se incluyeron 21 pacientes, 14 varones, con una mediana de edad de 11,4 años; 8 casos con feocromocitoma y 13 casos con paraganglioma. Se presentaron con hipertensión arterial 14/21. La mayoría de los paragangliomas tuvieron localización paraaórtica (9/13). Debido a que representan una causa potencialmente curable de hipertensión arterial, la sospecha clínica es muy importante. El diagnóstico temprano y la instauración de un tratamiento antihipertensivo adecuado, que permita afrontar la cirugía con normotensión arterial, aseguran la curación en la mayoría de los casos si la resección tumoral es completa.

Aproximaciones a la red de interacción entre abejas nocturnas y plantas con flores de Potrerillos de Güendá (Santa Cruz, Bolivia); Approximations to the interaction network between nocturnal bees and flowering plants from Potrerillos del Güendá (Santa Cruz, Bolivia) Crespo Cordero, Margarita Rosario; Almendras Gutierrez, Carol Andrea; Calcina Mamani, Selmy; Adler, Marcia; Benitez-Vieyra, Santiago Miguel Las abejas con hábitos crepusculares y nocturnos han sido pobremente estudiadas en Bolivia, donde la mayoría de los estudios han estado centrados en Apis mellifera. Las redes de interacción permiten cuantificar la biodiversidad y comprender fenómenos tanto naturales como de origen antrópicos y son de gran utilidad para el estudio de las interacciones planta-polinizador. Este trabajo se realizó en un bosque de transición de Amazonia y Bosque Seco Chiquitano, para conocer la intensidad y características de las interacciones entre abejas nocturnas y plantas locales, utilizando trampas de luz para capturar a las abejas nocturnas. Se colectaron 19 individuos durante tres noches. Identificamos cuatro especies de la familia Halictidae, tribu Augochlorini, de las cuales dos pertenecen al género Megalopta y dos son especies no identificadas de la misma tribu. Realizamos también una palinoteca del lugar y sus alrededores. Utilizando comparación morfológica entre los preparados de la palinoteca, los obtenidos de los cuerpos de las abejas y bibliografía especializada, encontramos doce morfoespecies de polen presentes en los cuerpos de las abejas, de las cuales tenía mayor frecuencia relativa los pertenecientes a las familias Lythraceae y Asteraceae. Como resultado tenemos una aproximación a la red de interacción, que nos permite indagar de manera mas profunda la interacción de este tipo de abejas y las plantas que visitan.; Bees with crepuscular and nocturnal habits have been poorly studied in Bolivia, where most studies have been focused on Apis mellifera. Interaction networks allow us to quantify biodiversity and understand both natural and anthropogenic phenomena and are very useful for the study of plant-pollinator interactions. This work was carried out in a transition forest of Amazonia and Chiquitano dry forest, in order to know the intensity and characteristics of the interactions between nocturnal bees and local plants, using light traps to capture nocturnal bees. We collected 19 individuals during three nights. We identified four species of the family Halictidae, tribe Augochlorini, of which two belong to the genus Megalopta and two are unidentified species of the same tribe. We also carried out a palynological survey of the site and its surroundings. Using morphological comparison between the preparations of the palynotheque, those obtained from the bee bodies and specialized bibliography, we found twelve morphospecies of pollen present in the bee bodies, of which those belonging to the families Lythraceae and Asteraceae had a higher relative frequency. As a result, we have an approximation to the interaction network, which allows us to investigate in a deeper way the interaction of this type of bees and the plants they visit.

Effects of climatic factors on carbohydrate composition of soybeans in Argentina Marioli Nobile, Carla Georgina; Balzarini, Monica Graciela; Grosso, Nelson; Soldini, Diego; Zossi, Silvia; Martínez, María José Carbohydrates are the second largest component of soybean seeds and include soluble sugars, a major source of energy. However, some oligosaccharides such as the raffinose family of oligosaccharides (RFOs) are considered antinutritional factors. In Argentina, the soybean crop area shows high climatic variation during the seedfilling period (R5–R7), affecting seed composition. The objective of this work was to evaluate the effect of climatic traits on carbohydrate (CHO) seed composition of different cultivar types. Daily air temperature and solar radiation were measured during R5–R7 in two soybean varieties: (non-transgenic) ALIM3.14 and a commercial. Precipitation and evapotranspiration during the crop season (R1–R7) were used to calculate a hydric balance proxy. ALIM 3.14 showed a better CHO profile than the commercial soybean. ALIM 3.14 had lower stachyose and total RFOs (25.1 and 28.9 g kg−1) than the commercial cultivar (37.3 and 42.3 g kg−1), respectively. Air temperature explained variations in CHO. A decrease in sucrose was observed with the increase in mean temperature (−2.65 g 100 g−1 per ˚C). Sucrose/total RFO and total sugar concentration also declined with increasing mean temperature −0.10 g 100 g−1 per ˚C and −0.35 g 100 g−1 per ˚C, respectively. Soybean with desired nutritional profile for specialties, such as high sucrose concentration and low raffinose, were obtained at cool temperatures (<19.4˚C) during seed filling. Producers and breeders can use this information to identify climatic variable thresholds that maximize the concentration of sugars in seeds and select traits and environments useful to improve soybean under climate warming conditions.

A new chitinozoan assemblage from the Middle Devonian Los Monos Formation (sub-Andean basin, southern Bolivia) and its biozonal implications for Western Gondwana Camina, Sonia Clara; Rubinstein, Claudia Viviana; Butcher, Anthony; García, Victoria Josefina; Vergani, Gustavo; Pereira, Martín Chitinozoans recovered from one section of the Middle Devonian Los Monos Formation in the TCB X-1001-Tacobo borehole, sub-Andean basin of Bolivia, have been analysed. Eleven from the eighteen processed cutting samples yielded specimens that allowed taxonomic study. Eleven genera and thirty-five chitinozoan species were identified from the Los Monos Formation with four of them recorded for the first time in Western Gondwana. Ancyrochitina biconstricta, Ancyrochitina parisi, Angochitina galarzae and Ramochitina boliviensis are among the most relevant taxa restricted to Western Gondwana that support the affinity with this paleocontinent. One new species, Lagenochitina tacobensis sp. nov. is described, and Ramochitina candelariaensis sp. nov. (n. n.) is formally erected. The chitinozoan assemblage reinforces the late Eifelian – middle Givetian age previously proposed by organic-walled phytoplankton and miospores for this section of the TCB X-1001-Tacobo borehole. A new local chitinozoan biozonation based on the chitinozoan assemblages is proposed and a revision of the current chitinozoan biozonation for Western Gondwana and Bolivia is recommended.

Kinematic modeling of neotectonic thrusts at the Andean orogenic front (southern Precordillera, Argentina) Richard, Andrés David; Costa, Carlos H.; Giambiagi, Laura Beatriz; Suriano, Julieta The south-central Andes located between 32◦-33◦ S are considered to be a transitional zone between the flatlyingand the normal subduction zones of the Nazca Plate. The active mountain-building processes are mainlyconcentrated between the Andean eastern foothills and the adjacent broken foreland, as highlighted by crustalseismicity, historic destructive earthquakes, and Quaternary-active contractional structures. Between 32◦ 10′ and32◦ 40′ S, the Andean orogenic front is exposed at the Las Pe˜nas-Las Higueras range, where east- and westvergingthrusts interact, resulting in an antithetic linkage transfer zone. We built kinematically-balancedstructural sections through the integration of surface and subsurface data (2D seismic lines) to achieve a 3Dcharacterization of the Quaternary-active thrusts and to estimate shortening rates of ~1.8–3.4 mm/a during thelast ~8.5 Ma, thus extending the spatial and temporal penetration achieved by surface geology data. Our resultsindicate that the main east-verging thrusts detach at a depth of ~10 km within Paleozoic basement rocks. Thisoutcome implies larger potential rupture areas than if rooted at Neogene layers. West-verging thrusts presentdetachment levels at ~5 km, also linked to Paleozoic basement rocks. The analysis of 2D seismic lines has alsocontributed to the recognition of blind thrusts without a morphologic signature, which could be regarded asrelevant seismogenic structures.

Dark energy based on exotic statistics Hoyuelos, Miguel Luis; Sisterna, P. Dark energy is an elusive concept, which has been introduced two decades ago in order to make the acceleration of the universe a comprehensible phenomenon. However, the nature of this energy is far from being understood, both from a fundamental as well as an observational way. In this work we study cosmological consequences of the existence of particles (which we called “ewkons” in a previous work) which are quasi distinguishable, obey unorthodox statistics, and have an equation of state similar to many existent dark energy candidates (including negative relation between pressure and energy density). We find an effective scalar field description of this ewkon fluid, and obtain cosmological solutions for the dark energy dominated epoch. This can be considered as a one-parameter class of dark energy models.

Photoproperties of favipiravir and its 6-substituted analogues: fluorescence controlled through halogen substitution and tautomerism Fuentes, Germán; Romero Cordero, Ivan Exehomio; Moller, Matías N.; Couto, Marcos; Romero, Angel H. Herein, we have showed the photophysical properties of favipiravir and its 6-substituted analogues. Also, we interpreted the origin of fluorescence of favipiravir and its 6-substituted analogues as a function of tautomerism modulation in ground and excited states. Favipiravir, the 6-fluorine derivative, showed the best photophysical profile, exhibiting a dominant emission wavelength of 430 nm, a high quantum yield (Q.Y.) of 1.0 and a long-lived state (10 ns). Its analogues also showed a maximum emission at 430 nm, but their Q.Y. values were 5-fold lower than that found for favipiravir, decreasing as a function of 6-substitution as follows: F > Cl > Br > I > H. Pyrazines bearing the least electronegative 6-substituent (X = Br, I, H) showed an extra lifetime, which was shorter (0.2–0.3 ns) and less abundant (>15%) than the main lifetime (10 ns, 85%). Further 2D excitation–emission matrix and solvent studies supported that these 3-hydroxy-2-pyrazinecarboxamides present two emissive states. The first of them (λem = 430 nm), which was the most abundant, most fluorescent and long-lived state, was characterized as “locally excited” (LE). Its fluorescence was favored with an increase of the hydrogendonor nature of the solvent and for pyrazines having a high enolic characteristic. Thus, the high LEfluorescence of these types of pyrazines depends on the keto-tautomerization of the ground state using a protic solvent and its feasible enol-tautomerization upon excitation. Finally, the second excited state (λem = 536 nm) was suggested as an excited-state intramolecular proton-transfer (ESIPT), and it was observed only, although discretely, for pyrazines bearing the least electronegative 6-substituent.

Thrombus discrimination with electron density: Potential implications for non-contrast computed tomography imaging Rodriguez Granillo, Gaston Alfredo; Cirio, Juan; Morales, Celina; Safady, Jorge; Fontana, Lucia; Fernandez, Martin; Diluca, Pablo; Lylyk, Pedro The potential clinical usefulness of electron density (ED) imaging, that can be directly estimated using dual-layer spectral computed tomography (CT), has been poorly investigated. We explored whether ED imaging might improve thrombus identification compared to conventional imaging in vitro. We evaluated mechanical thrombectomy material obtained from patients with acute ischemic stroke (AIS) treated in a tertiary level stroke center and immediately fixed in 10% neutral buffered formalin and stored in polystyrene test tubes. The test tubes were immersed in a bucket of water for evaluation by spectral CT, along with scattered control tubes. All images were obtained using a dual-layer detector CT scanner. Each tube was assessed using multiparametric side-by-side view of conventional CT (120 kVp), low monoenergetic imaging (40 keV), and ED images. Fifty-eight polystyrene tubes were analyzed, comprising 52 tubes with thrombectomy material of at least 1 mm2 size obtained from 52 AIS patients, and six control tubes filled with formalin. ED imaging identified accurately the presence of material in all tubes, whereas 2 (3%) of the tubes containing thrombus were not identified by conventional CT, leading to a very good agreement between observers for the presence of material using conventional CT and ED imaging (kappa =0.84, P<0.001). Using ED imaging, thrombus material showed a mean density of 108.8±2.9 percent ED relative to water (%EDW), water had a mean density of 100.0±0.3 %EDW, and formalin a mean density of 103.5±1.2 %EDW. Compared to conventional imaging and 40 keV monoenergetic, ED imaging had a significantly higher signal-to-noise ratio (conventional 10.4±7.0, vs. 40 keV 11.5±8.4, vs. ED 490.0±304.5, P<0.001) and contrast-to-noise ratio (CNR) (conventional 4.3±4.3, vs. 40 keV 5.7±11.2, vs. ED 37.8±29.1, P<0.001). In this in-vitro study, we demonstrated improved visualization of thrombus with ED imaging compared to conventional imaging and low monoenergetic imaging, with a significant increase in CNR.

Limits on quantum measurement engines Perna, Guillermo Ezequiel; Calzetta, Esteban Adolfo A quantum measurement involves energy exchanges between the system to be measured and the measuring apparatus. Some of them involve energy losses, for example because energy is dissipated into the environment or is spent in recording the measurement outcome. Moreover, these processes take time. For this reason, these exchanges must be taken into account in the analysis of a quantum measurement engine, and set limits to its efficiency and power. We propose a quantum engine based on a spin 1/2 particle in a magnetic field and study its limitations due to the quantum nature of the evolution. The coupling with the electromagnetic vacuum is taken into account and plays the role of a measurement apparatus. We fully study its dynamics, work, power, and efficiency.

Epidermal club cells in the cardinal tetra (Paracheirodon axelrodi): presence, distribution, and relationship to antipredator behavior Goodall, Jazmín; Rincón Camacho, Laura; Pozzi, Andrea Gabriela Epidermal club cells (ECCs) are present in many species of teleost fish. In an attempt to justify their presence in the epidermis of fish, they have been associated with numerous functions. One proposed function is communication with conspecifics during a predation event, as these cells may passively release substances upon rupture, which may occur during predation. We identified the presence and distribution of ECCs in the body skin of adult cardinal tetra, Paracheirodon axelrodi (Schultz, 1956) and analyzed the animal?s behavioral response to conspecific skin extract in a laboratory setting. The identification and distribution of ECCs in the epidermis of the animals were confirmed by conventional histology and immunohistochemistry. Our results demonstrated that: ECCs are present in the skin of the entire body; a high density is observed in the dorsal side from head to tail, in the insertion of the fins and in the epidermis covering them; and ventral distribution is less extensive and more dispersed than dorsal distribution. Treatment of P. axelrodi specimens with skin preparations of conspecifics resulted in behavioral changes in the animals: they showed erratic swimming movements, they showed avoidance of the area of stimulus application and they decreased the time spent moving. Overall, these results allow us to conclude that P. axelrodi possesses ECCs throughout the body, with a greater presence in areas of high exposure to predation events (dorsal area and fins). Animals exposed to conspecific skin extract showed a significant increase in behaviors described as anti-predatory in other species. This supports the hypothesis that ECCs may be the origin of chemical alarm cues that are passively released when skin damage occurs, alerting the rest of the group to the risk of predation.

The MVA vector expressing the F protein of bovine respiratory syncytial virus is immunogenic in systemic and mucosal immunization routes; El vector viral MVA que expresa la proteína F del virus respiratorio sincicial bovino es inmunogénico al administrarse por vía sistémica y por mucosas Ferella, Alejandra; Mozgovoj, Marina Valeria; Garanzini, Débora Patricia; Dus Santos, María José; Calamante, Gabriela; del Medico Zajac, Maria Paula Bovine respiratory syncytial virus (BRSV) affects both beef and dairy cattle, reaching morbidity and mortality rates of 60-80% and 20%, respectively. The aim of this study was to obtain a recombinant MVA expressing the BRSV F protein (MVA-F) as a vaccine against BRSV and to evaluate the immune response induced by MVA-F after systemic immunization in homologous and heterologous vaccination (MVA-F alone or combined with a subunit vaccine), and after intranasal immunization of mice. MVA-F administered by intraperitoneal route in a homologous scheme elicited levels of neutralizing antibodies similar to those obtained with inactivated BRSV as well as better levels of IFN-γ secretion. In addition, nasal administration of MVA-F elicited local and systemic immunity with a Th1 profile. This study suggests that MVA-F is a good candidate for further evaluations combining intranasal and intramuscular routes, in order to induce local and systemic immune responses, to improve the vaccine efficacy against BRSV infection.; El virus respiratorio sincicial bovino (BRSV) afecta al ganado bovino de cría y lechero, con niveles de morbilidad del 60-80% y de mortalidad del 20%. El objetivo de este trabajo fue obtener virus MVA recombinantes que expresen la proteína F de BRSV (MVA-F) como candidato vacunal contra BRSV y evaluar la respuesta inmune inducida por dicho virus luego de administrarse por vía sistémica, tanto en esquemas de vacunación homóloga como heteróloga (MVA-F solo o combinado con una vacuna a subunidad proteica), y luego de su inoculación intranasal en ratones. La administración de MVA-F por vía intraperitoneal en un esquema homólogo indujo niveles de anticuerpos neutralizantes similares a los obtenidos con una vacuna inactivada de BRSV, así como niveles superiores de secreción de IFN-γ. Además, la inoculación intranasal de MVA-F indujo inmunidad local y sistémica, con un perfil de respuesta de tipo Th1. Este estudio sugiere que MVA-F es un buen candidato para continuar su evaluación combinando las vías nasal e intramuscular para de este modo inducir respuesta local y sistémica y así mejorar la eficacia contra la infección por BRSV.

Investigating Fishing Vessel Hydrodynamics by Using EFD and CFD Tools, with Focus on Total Ship Resistance and Its Components Oyuela, Sebastian; Ojeda, Héctor Rubén Díaz; Arribas, Francisco Pérez; Otero, Alejandro Daniel; Sosa, Roberto The aim of this work is to gain a better understanding of the hydrodynamics of a typical Argentinian fishing vessel in calm water. It is focused on the evaluation of total ship resistance and its components for different draughts. The 1978 ITTC Power Prediction method is used to predict total ship resistance from experiments carried out at the University of Buenos Aires towing tank. To conduct a more detailed evaluation of the flow around this hull, numerical studies at model scale are carried out with the open-source code OpenFOAM V10 and validated against experimental results. The Reynolds-Averaged Navier–Stokes (RANS) method together with Volume of Fluid (VOF) are used for the numerical procedure. The validated CFD model not only can provide more detailed information about the ship’s hydrodynamics than the EFD results but also allows for the exploration of the improvement in ship power prediction by using combined CFD-EFD methodologies. This work numerically calculates the form factor by using a double-body configuration and discusses the possibility of combining EFD results with this CFD form factor in order to improve total force prediction for this kind of ships.

Abastecimiento de obsidiana en Los Andes: Aplicación de un modelo de distancia anisotrópica en el Área de Laguna del Diamante (S34ª); Obsidian supply in The Andes: Aplication of an anistropic distance model in The Laguna del diamante Area (S 34ª) Yebra, Lucía Gabriela; Cortegoso, Valeria; Castro, Silvina Celeste; Lucero, Gustavo Se prueba un modelo de distancia anisotrópica elaborado en SIG para evaluar costos de desplazamiento en ambientes con topografías abruptas en función de la pendiente y tiempo recorrido(Lucero et al., 2021). Se aplican rangos propuestos (locales, no locales y extrarregionales)para evaluar costos de aprovisionamiento y cambios en el acceso a las fuentes de obsidiana:Arroyo Paramillos y Laguna del Diamante. Se evalúa la distribución de artefactos con análisisgeoquímicos asignados a estas fuentes considerando la disponibilidad anual/estacional de sitiosa partir de un análisis SIG de cobertura nívea. El decrecimiento de obsidianas sigue tendenciasesperables de acuerdo con el fall-off de las fuentes, aunque es asimétrico a uno y otro lado delos Andes. Tendencias espaciales no esperables pueden explicarse por la localización de emplazamientos en umbrales variables de estacionalidad y acceso en función de cambios ambientales pero también sociales vinculados a la territorialización del espacio.; An anisotropic GIS distance model based on slope and travel time is tested to evaluate travel costs in environments with steep topographies (Lucero et al. 2021). The proposed ranges (local, non-local and extra-regional) are applied to evaluate supply costs and changes in access to obsidian sources: Arroyo Paramillos and Laguna del Diamante. The distribution of artifacts with geochemical analyzes assigned to these sources is evaluated; annual/seasonal availability of the sites from a snow cover analysis with GIS has also been considered. The decrease in obsidian follows the expected trends according to the decrease in sources, although it is asymmetric on both slopes of the Andes. Unexpected spatial trends can be explained by the location of sites at variable thresholds of seasonality and access depending on environmental changes, but also by social changes associated with the territorializing of space.

Conjugated linoleic acid‐enriched yoghurts development through homogenization: Study of fatty acids, volatile compounds profiles and physicochemical, rheological and sensory properties Vélez, María Ayelén; Wolf, Irma Veronica; Zeiter, Agustin Leo; Caballero Reinhardt, María Soledad; Spotti, María Julia; Cuffia, Facundo; Perotti, Maria Cristina Conjugated linoleic acid (CLA) is recognised for its health benefits: anticancer, antiinflamatory and antiatherogenic effects have been reported. CLA enriched yoghurts were developed through homogenization at two levels (H1 and H2 with 40 and 80 mg CLA/100 g of yoghurt, respectively) with a view to creating functional foods. CLA modified the volatile profile in a positive way: higher levels of diacetyl and ethyl butanoate and lower values of 2-hexanone and 2-heptanone, ethanol and certain acids were recorded. Yoghurts presented similar microstructure, but H1 showed higher consistency and lower pseudoplastic behaviour; meanwhile H2 presented less syneresis. All products had high acceptability.

Semblanza de victoria ocampo Kratje, Julia Victoria Ocampo (1890-1979) es bien conocida en su rol de fundadora de la revista Sur (1931-1970) y de la editorial Sur (1933-1985), un proyecto cultural de alto impacto en América Latina que funcionó como enlace entre la intelectualidad argentina, americana y europea. Pero fue, además, una activa feminista, escritora, traductora y cronista; entusiasta “escribidora” de cartas –solía decir– y viajera. Ejerció una extraordinaria labor de gestión, difusión, mecenazgo y promoción cultural. Más allá de su vasta obra (diez volúmenes de Testimonios y seis de su Autobiografía, y entre 1924 y 1969 publicó unos quince libros de ensayos y crónicas), entre sus hazañas se cuenta haber sido la única mujer civil sudamericana en asistir a los juicios de Núremberg, haberle dado asilo a intelectuales y artistas que huían de los fascismos europeos, o en una nota quizá más snob se puede mencionar que gracias a ella Gisèle Freund le sacó a Virginia Woolf una de sus fotos más distintivas. También fue la primera mujer miembro de la Academia Argentina de Letras. Ese año, en 1977, mientras la revista Somos se mofaba de su figura, entre las múltiples cartas de mujeres que la homenajearon, la Federación Argentina de Mujeres Universitarias le escribía al presidente de la Academia: “Lo auspicioso de la decisión no está en haber elegido a una mujer para ocupar un asiento en esa honorable corporación; está sí en haber elegido a una señora escritora de largo y merecido prestigio, que ha dado claro y valiente testimonio de su amor por la libertad, de apasionado ejercicio de una vocación y de ininterrumpida dedicación al estímulo y a la difusión del pensamiento”.