Cytotoxic and genotoxic effects induced by enrofloxacin-based antibiotic formulation Floxagen® in two experimental models of bovine cells in vitro: peripheral lymphocytes and cumulus cells Anchordoquy, Juan Patricio; Anchordoquy, Juan Mateo; Nikoloff, Noelia; Gambaro, Rocío Celeste; Padula, Gisel; Furnus, Cecilia Cristina; Seoane, Analia Isabel The in vitro effect of enrofloxacin (EFZ) was tested on two experimental somatic bovine cells in vitro: peripheral lymphocytes (PLs) and cumulus cells (CCs). The cytotoxicity and genotoxicity of this veterinary antibiotic were assessed using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays, single-cell gel electrophoresis (SCGE) assay, and cytokinesis-block micronucleus cytome (CBMN cyt) assay. Cells were treated during 24 h, and three concentrations were tested (50 μg/mL, 100 μg/mL, 150 μg/mL). When EFZ was tested in PLs, the results demonstrated that the antibiotic was able to induce cell death and DNA damage with all concentrations. In addition, 50 μg/mL and 100 μg/mL EFZ increased frequencies of micronuclei (MNi). On the other hand, the highest EFZ concentration occasioned cellular cytotoxicity in CCs as evidenced by mitochondrial activity alterations. Nevertheless, EFZ was not able to induce DNA damage and MNi in CCs. These results represent the first experimental evidence of genotoxic and cytotoxic effects exerted by EFZ in bovine PLs and CCs.

Inhibition of antigen presentation by Brucella: many more than many ways Barrionuevo, Paula; Giambartolomei, Guillermo Hernan Brucella infection activates the immune system and favors the differentiation of CD4+ and CD8+ T cells. To persist during a long time inside macrophages evading immune surveillance of these T cells the pathogen must exploit different evasion strategies. We review the mechanisms whereby Brucella, through TLR signaling, inhibits MHC class I and II antigen presentation, allowing infected macrophages to become effective niches for Brucella survival.

Effects of one-step alkaline and two-step alkaline/dilute acid and alkaline/steam explosion pretreatments on the structure of isolated pine lignin Das, Parthapratim; Stoffel, Romina Bettiana; Area, Maria Cristina; Ragauskas, Arthur J. Biological valorization of biomass most often depends on the efficient reduction of plant cell wall recalcitrance and conversion of lignin – the most recalcitrant constituent – to fuels, chemicals and/or value-added substances. Lignin conversion to fuels and value-added chemicals requires a sound understanding of the structure of lignin before and after different pretreatments. In the current work, an effort has been made to compare the structural differences in isolated pine lignin after one- (alkaline) and two-step (alkaline/dilute acid and alkaline/steam explosion) pretreatments. Our results indicate removal of the low molecular weight fraction of lignin after an initial alkaline pretreatment. A subsequent dilute acid pretreatment resulted in the loss of lignin inter-unit linkages such as β-O-4’ aryl ethers. However, with a steam explosion pretreatment, lignin exhibited a competing condensation process leading to increased condensed lignin structures.

Influence of {111} nanofaceting on the dynamics of CO adsorption and oxidation over Au supported on CeO 2 nanocubes: An operando DRIFT insight Fernández García, Susana; Collins, Sebastián Enrique; Tinoco, Miguel; Hungría, Ana B.; Calvino, José J.; Cauqui, Miguel A.; Chen, Xiaowei CO adsorption and further reaction with O 2 on two Au/CeO 2 model systems have been investigated by operando diffuse reflectance infrared Fourier transform spectroscopy (DRIFT) in order to unveil the active sites for CO oxidation. One of the ceria supports was constituted by crystallites depicting a nanocube shape bounded mostly by {100} planes, whilst the second one was consisted of nanocubes whose {110} surfaces were reconstructed into {111}-nanofacets with a zig-zag shape. The deconvolution of the CO adsorption bands and a detailed analysis of the time-evolution of these bands were also carried out. These studies evidenced a fast adsorption of CO over Au° and then Au δ- -CO bands appeared during exposure to CO, in parallel with the appearance of Ce 3+ features. Such changes suggest that CO adsorption process starts on Au sites on the low coordinated sites of the surface of the Au nanoparticles and their transfer to the interface sites. By comparing the nanostructure of the two catalysts, the Au δ- -CO species could be fruitfully related to CO adsorption on sites located at the Au||CeO 2 perimeter. The sample containing gold nanoparticles dispersed over the {111}-nanofaceted CeO 2 nanocubes, which retained a higher amount of gold nanoparticles, depicts higher contribution of Au δ− −CO bands than the other Au catalyst in the DRIFT spectra. The dynamic DRIFT study clearly revealed that the CO species adsorbed on Au δ- sites were the most reactive ones in both gold supported systems for CO oxidation. This explains much higher TOF values observed on the catalyst prepared on the surface reconstructed support. A detailed analysis on the reactivity was performed by modulation excitation spectroscopy (MES). The presence of peroxide surface species (O 2 2- ) in nanofaceted {111} could lead to higher catalytic activity than that of gold on the non-reconstructed catalyst.

Recognition of species groups of Naupactus Dejean (Coleoptera: Curculionidae) from Argentina and neighboring countries del Rio, Maria Guadalupe; Lanteri, Analía Alicia Naupactus Dejean is the most diverse genus of the tribe Naupactini (Curculionidae: Entiminae), with more than 200 species occurring in South America, of which about 40 range in Argentina and neighboring countries. The Argentinean species treated herein were classified into nine groups having different biogeographic patterns: (1) the groups of Naupactus xanthographus, N. delicatulus and N. auricinctus mainly occur in northeastern Argentina (Misiones province) and reach the highest species diversity in the Atlantic and Parana forests of Brazil; (2) the groups of N. hirtellus, N. cinereidorsum, N. rivulosus and N. tarsalis show the highest species diversity in the Chacoan biogeographic province and also occur in the Yungas, Espinal, Monte, Parana forest (Argentina) and Cerrado (Brazil); (3) the groups of N. leucoloma and N. purpureoviolaceus have the highest species diversity in the Pampean biogeographic province, being also present in adjoining areas, mainly Chaco, Espinal, Monte and Parana forest. We provide descriptions, a dichotomous key, habitus photographs and line drawings of genitalia for the identification of the nine species groups, and a list of the Argentinean species from each group, together with their abbreviated synonymies, updated geographic distributions (including six new country records and several state/province records) and host plant associations. We discuss the characters that allow the separation of the species groups in a geographic distribution context, and provide information on species reassigned to genera other than Naupactus; among these, we transferred N. cephalotes (Hustache) to the tribe Tanymecini, genus Eurymetopellus, establishing the new combination Eurymetopellus cephalotes.

Role of the Hsp90-immunophilin heterocomplex in cancer disease de Leo, Sonia Alejandra; Zgajnar, Nadia Romina; Mazaira, Gisela Ileana; Erlejman, Alejandra Giselle; Galigniana, Mario Daniel The identification of new factors that may function as cancer markers and becomeeventual pharmacologic targets is a challenge that may influence the management of tumor developmentand management. Recent discoveries connecting Hsp90-binding immunophilins with theregulation of signalling events that can modulate cancer progression transform this family of proteinsin potential unconventional factors that may impact on the screening and diagnosis of malignantdiseases. Immunophilins are molecular chaperones that group a family of intracellular receptorsfor immunosuppressive compounds. A subfamily of the immunophilin family is characterizedby showing structural tetratricopeptide repeats, protein domains that are able to interact with theC-terminal end of the molecular chaperone Hsp90, and via the proper Hsp90-immunophilin complex,the biological properties of a number of client-proteins involved in cancer biology are modulated.Recent discoveries have demonstrated that two of the most studied members of this Hsp90-binding subfamily of immunophilins, FKBP51 and FKBP52, participate in several cellular processessuch as apoptosis, carcinogenesis progression, and chemoresistance. While the expressionlevels of some members of the immunophilin family are affected in both cancer cell lines andhuman cancer tissues compared to normal samples, novel regulatory mechanisms have emergedduring the last few years for several client-factors of immunophilins that are major players in cancerdevelopment and progression, among them steroid receptors, the transctiption factor NF-κBand the catalytic subunit of telomerase, hTERT. In this review, recent findings related to the biologicalproperties of both iconic Hsp90-binding immunophilins, FKBP51 and FKBP52, are reviewedwithin the context of their interactions with those chaperoned client-factors. The potentialroles of both immunophilins as potential cancer biomarkers and non-conventional pharmacologictargets for cancer treatment are discussed.Keywords: Heat-shock proteins; immunophilins; cancer; peptidylprolyl isomerase;

Determination of 2-hydroxy-4-methoxybenzophenone in mice serum and human plasma by ultra-high-performance liquid chromatography enhanced by chemometrics Teglia, Carla Mariela; Santamaría, Clarisa Guillermina; Rodriguez, Horacio Adolfo; Culzoni, Maria Julia; Goicoechea, Hector Casimiro This work presents the development of a strategy for the quantitation of 2-hydroxy-4-methoxybenzophenone (BP-3) in mice serum and human plasma. The instrumental determination only lasts 2 min and is based on ultra-high-performance liquid chromatography (UHPLC) coupled to second-order data modeling with multivariate curve resolution-alternating least-squares (MCR-ALS). Coelution of BP-3 with the matrix components was resolved by exploiting the second-order advantage of multi-way calibration. The validation study led to the following results: linear range from 0.002 to 1.509 μg mL−1; in the case of mice serum samples: recoveries from 95 to 98%, with intra and inter day precision of 2.7 and 5.7, respectively; and in the case of human plasma samples: recoveries from 94 to 99% with intra and inter day precision of 2.3 and 4.6%, respectively. Special emphasis was put on the determination of the LOD and LOQ by utilizing several approaches for their calculation and making focus on the experimental verification of the figures provided by the multivariate methodology. Following the mentioned approach, the LOD and LOQ of the method were estimated as 0.66 and 2.00 ng mL−1, respectively. Eventually, the method was successfully applied to the determination of BP-3 in mice serum.

Enzymatic synthesis of non-natural trisaccharides and galactosides; Insights of their interaction with galectins as a function of their structure Porciúncula González, Cecilia; Cagnoni, Alejandro; Mariño, Karina Valeria; Fontana, Carolina; Saenz Méndez, Patricia; Irazoqui, Gabriela; Giacomini, Cecilia Galectins are a family of carbohydrate-recognizing proteins that by interacting with specific glycoepitopes can mediate important biological processes, including immune cell homeostasis and activation of tolerogenic circuits. Among the different members of this family, Galectin 1 and 3 have shown pro-tumorigenic effects, being overexpressed in numerous neoplasic diseases, proving to be relevant in tumor immune escape, tumor progression and resistance to drug-induced apoptosis. Thus, generation of specific glycosides that could inhibit their pro-tumorigenic ability by blocking their carbohydrate recognition domain is one of the current major challenges in the field. Considering that galectin-ligand binding strength is closely related to the ligand structure, analysis of this relationship provides valuable information for rational design of high-affinity ligands that could work as effective galectin inhibitors. Taking profit of the ability of glycosidases to catalyze transglycosylation reactions we achieved the enzymatic synthesis of β- D -Galp-(1 → 6)-β- D -Galp-(1 → 4)- D -Glcp (2), a mixture of β- D -Galp-(1 → 6)-β- D -Glcp-(1 → 4)- D -Glcp (5) and β- D -Galp-(1 → 3)-β- D -Glcp-(1 → 4)- D -Glcp (6), and finally benzyl β-D -galactopyranoside (9), with reaction yields between 16 and 27%. All the galactosides were purified, and characterized using 1 H and 13 C nuclear magnetic resonance spectroscopy. Docking results performed between the synthesized compounds and human Galectin 1 (hGal-1) and human Galectin 3 (hGal-3) showed that the replacement of a glucose moiety linked to the terminal galactose with a galactose moiety, decreases the affinity for these galectins. Moreover, regarding the interglycosidic bond the most favorable β-Gal linkage seems to be β(1 → 4) followed by β(1 → 3) and β(1 → 6) for hGal-1, and β(1 → 4) followed by β(1 → 6) and β(1 → 3) for hGal-3. These results were in accordance with the IC50 values obtained with in vitro solid phase inhibition assays. Therefore, docking results obtained in this work proved to be a very good approximation for predicting binding affinity of novel galactosides.

The Puesto Piris Formation: Evidence of basin-development in the North Patagonian Massif during crustal extension associated with Gondwana breakup Strazzere, Leonardo; Gregori, Daniel Alfredo; Benedini, Leonardo; Marcos, Paulo; Barros, Mercedes Virginia; Geraldes, Mauro C.; Pavon Pivetta, Cecilia Mariana The Marifil Volcanic Complex, exposed in the eastern North Patagonian Massif, Argentina, includes up to 550 m of red conglomerates, sandstones, black siltstones, limestones, and reworked tuff of the Puesto Piris Formation. The basal part of this unit, which was deposited in high-gradient topographic relief, is composed of conglomerates and sandstones with thin layers of reworked tuffs. The lithofacies associations of the basal part indicate that the depositional mechanisms were mantled and gravitational flows. The middle part of the unit consists of fine sandstones, limestones, and black siltstones that were deposited in low-energy fluvial and lacustrine environments. The outcrops are located along the NE–SW direction and the major thickest units represented by limestones and siltstones, occur near the southeastern border of this NE–SW depocenter. Since the rhyolitic and trachytic lava flows and tuffs of the Marifil Volcanic Complex are interbedded with the sedimentary sequences of the Puesto Piris Formation, both units are coeval. Zircon U–Pb age was obtained for a trachytic lava flow (193.4 ± 3.1 Ma) suggesting that sedimentation and volcanism are Sinemurian. This extensional episode was recorded in the eastern, western, and southwestern sectors of the North Patagonian Massif, and is possibly associated with the Gondwana supercontinent breakup.

Nitrogen balance in a plant-soil system under different cover crop-soybean cropping in Argentina Landriscini, María Rosa; Galantini, Juan Alberto; Duval, Matias Ezequiel; Capurro, Julia E. Cover crops (CC) provide many benefits for the soil and the following crop but their effects on nitrogen (N) release and balance in continuous no-tillage soybean (Glycine max L. Merr.) production are little known. Estimation of the biological nitrogen fixation (BNF) in intensive agricultural systems under soybean is essential to understanding the N dynamics and to determining the balances and crop demands. This study (2006–2011) was performed on a Typic Argiudoll under no-tillage in the province of Santa Fe, Argentina. The aims were to study the effect of fall winter CC, such as wheat (W), oats (O), oats + vetch (O + V) and vetch (V), on the yield and N-content of the following crop (soybean) and to quantify the contribution of the BNF and N-balance. Three methodologies were used for BNF estimation: 1) a linear regression model between BNF and N-uptake by soybean; 2) the natural 15N abundance in soybean and 3) the average BNF in the Pampa region. Gramineous CC developed more dry matter than pure legume species, with intermediate values for the gramineous-legume mixture. Biological fixation provides 60–70% of absorbed N, according to the estimation method. Within the rainfall range of 500–1000 mm during the soybean cycle, CC did not affect the grain yield or soybean dry matter production. The partial N-balance was always positive, with differences between the techniques used for BNF estimation. Cover crops have contributed to the positive soil N-balance. Gramineous CC stored 22% more N-content in the soil surface layer than the others. Cover crops showed 15% higher index of N-stratification on the surface compared to the control soil. Using CC would be an efficient alternative to produce biomass and to supply N to the soil for the subsequent crop.

New remains of Nothrotheriinae (Mammalia, Xenarthra) from Late Pleistocene fluvial deposits of Northern Pampa (Santa Fe Province, Argentina) Vezzosi, Raúl Ignacio; Brandoni, Diego; Brunetto, Ernesto; Zalazar, Maria Cecilia In this contribution the record of a Nothrotheriinae (Xenarthra, Tardigrada) ground sloth is reported from the Late Pleistocene of the Northern Pampa of Santa Fe Province, Argentina. The stratigraphic unit where the fossil was collected corresponds to fluvial-palustrine sediments of the Timbúes Formation, outcropping along the Carcarañá River valley. The relative stratigraphic position of this lithostratigraphic unit, observed in several sections mainly on the Paraná River cliffs near Carcarañá River distal area, suggests that it was deposited during the Last Interglacial Stage. The specimen (MPAHND-135), assigned to Nothrotherium cf. torresi, is represented by the proximal two-thirds of a left femur that shows a prominent lesser trochanter and no connection between the third trochanter and the ectepicondyle. The presence of Nothrotherium cf. torresi in sediments related to humid conditions supports the idea that Nothrotheriinae had great ecological tolerance and was capable of inhabiting climates ranging from cold and arid, as was previously proposed, to warm and humid.

Thermal evolution of upper crustal magmatic systems from the Sierra de Velasco, NW Argentina Macchioli Grande, Marcos Simón; Alasino, Pablo Horacio; Rocher, Sebastian; Larrovere, Mariano Alexis; Uran, Gimena Mariel; Reinoso Carbonell, Virginia Valeria; Moreno, Gabriel Detailed mapping of the Huaco intrusive Complex in NW Argentina documents a shift in the emplacement style of successive magma additions in an upper crustal environment as the system evolves thermally. The units of the Huaco intrusive complex exhibit a change from a tabular to funnel-shaped subhorizontal body (Huaco unit) with stoping and brittle fracturing as main emplacement mechanisms, to a cylindrical body (Sanagasta unit), emplaced in a heated host rock which shows local ductile behaviour. As the system cools, the youngest intrusion (La Chinchilla unit) emplaces again as a subhorizontal tabular to funnel-shaped body. Furthermore, magmatic fabrics recorded a regional strain field that changed from a SW-NE to WSW-ENE shortening, as well as boundary strain increments and stress reorientation. Our results demonstrate that the evolution of magma chambers involves the emplacement of magma batches in a stiff crust, changing its thermal conditions and maturing the system for following intrusions. The latter ascend as visco-elastic elongated bodies using the same magmatic plumbing system, leading to a shift in the emplacement style. The described evolution is similar to that reported for the contemporaneous San Blas intrusive Complex located in the same range. This allows us to affirm that these processes are recurrent in the upper crustal section, and that the thermal and rheological conditions of the crust are locally modified by the formation and evolution of long-lived magma reservoirs.

El diablo y su cola en el Lago Titicaca Costilla, Julia El santuario boliviano de Copacabana como ejemplo del mestizaje religioso de catolicismohispánico con creencias indígenas legado por la sociedad colonial.

Phylogenetic placement of the Peruvian-endemic genus Machaerophorus (Brassicaceae) based on molecular data and implication for its systematics Salariato, Diego Leonel; Cueva Manchego, Marco A.; Cano, Asunción; Al-Shehbaz, Ihsan The genus Machaerophorus includes three perennial species (M. arequipa, M. laticarpus, and M. matthioloides) inhabiting the southern Peruvian Andes. However, based on the morphological data, this genus has been reduced for more than one hundred years to synonymy of several genera of various tribes, and its phylogenetic placement using molecular data has never been studied. Therefore, in this study we explored the phylogenetic placement of Machaerophorus to test its generic status and tribal assignment, using for this purpose ribosomal nuclear (ITS) and chloroplast (trnL-F, trnH-psbA, rps16 intron) data together with a comprehensive sampling of taxa. Results obtained here demonstrated that Machaerophorus represents a well-differentiated lineage within the South American Cremolobeae–Eudemeae–Schizopetaleae clade, and hence, the genus is reinstated and excluded from the placements in Sibara and Mathewsia. Based on molecular data and morphological affinities, we included it within the tribe Schizopetaleae. A key to Machaerophorus and the genera of Schizopetaleae is also presented.

Spatial organization and habitat selection of Geoffroy's cat in the Espinal of central Argentina Castillo, Diego Fabián; Luengos Vidal, Estela Maris; Caruso, Nicolás; Manfredi, Matilde Claudia; Lucherini, Mauro; Casanave, Emma Beatriz We report data on the spatial ecology and habitat selection of eight adult Geoffroy's cat Leopardus geoffroyi (five males and three females) that were radiotracked in an area of the central Argentine Espinal. Mean home range size varied from 2.2 ± 1.9 km2 (Kernel95%) to 2.8 ± 2.4 km2 (MCP100%), with male home ranges 4.1 larger than those of females. Core areas (Kernel50%) averaged 0.7 ± 0.7 km2 and were 3 times smaller for females. Daily movement patterns were consistent with the variations in home range sizes being greater in males (590.2 m ± 476.6) than females (413.5 m ± 288.1). Home range overlap averaged 38%, and was highly variable between males and females and reached its highest value for intersexual pairs. At second-order resolution, most of individuals had a strong selection for open woodland, while the other habitats were generally avoided. At the home range level, although the electivity index values for the open woodland were positive for all animals, habitat selection showed a high inter-individual variation. Our data support previous studies that suggest that Geoffroy's cats show a certain degree of flexibility in their spatial behavior. Finally, we argue that natural woodland patches or habitats with dense vegetation are important for L. geoffroyi in the Argentinean Espinal and their alteration can affect the conservation status of this cat.

Electronic transport in a graphene single layer: Application in amino acid sensing Rodríguez Sotelo, Sindy Julieth; Albanesi, Eduardo Aldo We modeled a type of field-effect transistor device based on graphene for the recognition of amino acids with a potential application in the building of a protein sequencer. The theoretical model used was a combination of density functional theory (DFT) with the non-equilibrium Green's function (NEGF) in order to describe the coherent transport in molecular devices. First, we studied the physisorption of each amino acid on a graphene sheet and we reported the adsorption energy, the adsorption distances, the equilibrium configuration and the charge transfer of ten amino acids that can be considered as representative of all of the amino acids: histidine (His), alanine (Ala), aspartic acid (Asp), tyrosine (Tyr), arginine (Arg), glutamic acid (Glu), glycine (Gly), phenylalanine (Phe), proline (Pro) and lysine (Lys). As a result, significant differences were found in the density of states (DOS) after adsorption and there was a change in the semi-metallic character of the graphene due to the lysine and arginine interactions. Furthermore, we noticed changes in the electrical characteristics of the devices, as the amino acids adsorbed onto the surface of the graphene. The curves of current vs. bias voltage (I-Vb) display a distinct response for each amino acid, i.e. the I-Vb curves produce a characteristic footprint for each amino acid. We identified a possible rectification mechanism related to the voltage profile asymmetry, where the amino acids can control the transport characteristics in the device, i.e. Lys and Phe amino acids physisorbed on graphene act as a molecular diode, where electrons can easily flow in one direction and decrease in the other. This may be promising for the prospect of biosensors: graphene could be used as an amino acid detector.

Temporomandibular joint osteoarthritis in human ancient skeletal remains from Late Holocene in southern Patagonia Suby, Jorge Alejandro; Giberto, Diego Agustin Low prevalence of caries, high stages of dental attrition (DA), and moderate frequency of antemortem tooth loss (AMTL) were found in skeletal remains of hunter-gatherers from southern Patagonia. However, osteoarthritis (OA) of temporomandibular joint (TMJ), possible related to oral health, has not been studied so far. The influence of hunter-gatherer living conditions on the development of TMJ-OA was scarcely evaluated, and analyses of degenerative changes of TMJ in nonindustrialized groups are needed. The aim of this study is to analyse the association between degenerative changes of TMJ, oral disease, and palaeodietary patterns in skeletal remains of hunter-gatherers from southern Patagonia. Degenerative changes of TMJ were recorded in 25 adult skulls of both sexes. Eburnation of articular eminence and/or mandibular condyle was considered as pathognomonic of OA. In the absence of eburnation, OA was diagnosed when two or more of the following lesions were identified: (a) new bone formation on joint surface, (b) new bone formation of joint margins, (c) porosity on the joint surface, and (d) modification of joint contour. In the studied skeletons, it was found that OA prevalence is 28%, similar to those observed in other hunter-gatherer populations elsewhere. TMJ-OA is mostly related to AMTL and older age, but no relation was found with caries and DA, sex, region, dietary patterns, and chronology. However, consumption of terrestrial resources in the diet cannot be discarded as a related factor. Further studies are necessary to explore the morphological variability of the mandible and its possible relationship with different diets and dental pathologies in these populations.

Las relaciones con el Bloque del Este desde el punto de vista de las emociones de los diplomáticos argentinos en tiempos de Guerra Fría. El caso de las campañas de repatriación a los países socialistas (1955-1961) Galván, Maria Valeria Este trabajo analiza los discursos de los diplomáticos argentinos en legaciones del Bloque Comunista en Europa del Este, acerca de las campañas de repatriación socialistas que afectaron a las comunidades locales de inmigrantes eslavos en Argentina, entre los años 1955-1961.Las valoraciones de los diplomáticos sobre las consecuencias de la campaña para la población local y para la gestión estatal argentina sirvieron como base para las presiones que la Cancillería ejerció regularmente sobre los organismos de inteligencia dependientes del Ministerio del Interior, con el objetivo de reforzar la seguridad interna y controlar los efectos de esta campaña propagandística en suelo argentino.; This paper analyzes the discourse of Argentine diplomats in countries of the Communist Bloc in Eastern Europe on the Socialist repatriation campaigns and their consequences on the local communities of Slavic immigrants in Argentina, between the years 1955-1961. The emotional attachment of the diplomats towards the consequences of the campaign on the local population and on the local State administration served as a basis for the claims that the Argentinean Foreign Office presented regularly to the intelligence divisions of the Ministry of Internal Affairs, in order to reinforce internal security and mechanisms of control against the impact of this propaganda campaign on Argentinean soil.

Hacia una analítica del sensorium común: Apuntes para una morfología estético-política de lo social; Towards an analysis of the common sensorium: Notes for an aesthetic-political morphology of the social dimension Mallamaci, Marco German Tanto frente al avance de los medios electrónicos y las teletransmisiones del siglo XX como frente a la digitalización cibernética del siglo XXI, los diversos campos epistémicos se han encargado de problematizar la relación entre lo perceptivo, lo estético (espacio-tiempo) y los cambios tecnológicos que imponen nuevas prácticas intersubjetivas, comportamientos y mod os de subjetivación. En muchos autores surge el uso de un concepto puntual: el sensorium. Ya sea que se proponga un enfoque cultural o una perspectiva específicamente gnoseológica, suele r epetirse una referencia de dicha categoría en relación con los cambios de la velocidad y la aceleración de las imágenes, los textos y las comunicaciones; primero en la era de la electrónica analógica y luego en la época digital. El objetivo de este trabajo es exponer una breve sistematización del concepto de sensorium en vistas de una posible definición en tanto unidad de análisis estético-política. Dicha categoría permite, por un lado, pensar la disciplina Estética como pensamiento político ; y por el otro, pensar lo político en clave estética. Para ello el texto repasa los diversos sentidos que ha tenido la categoría a lo largo de la historia, según su emergencia en diferentes epistemes. La primera parte recorre ciertos discursos puntuales identificando autores en los cuales se pueden encontrar usos específicos (Newton, Simmel, Benjamin, McLuhan, Kittler, etc.), delineando así una serie de sentidos relacionados con el espacio y el tiempo desde lo estético, lo perceptivo, lo gnoseológico, lo sociológico y lo técnico. A partir de dicho esquema, en la segunda parte se presenta la idea de un ?giro sensorial? en los estudios sociopolíticos contemporáneos, donde la idea de sensorium cobra una nueva importancia. Por último, se hace foco en las relaciones conceptuales que se derivan del uso que propone Rancière en torno a la categoría. En base a dicho recorrido el texto busca delinear una serie de elementos para abrir la posibilidad de definir la Estética como el pensamiento del sensorium común; se trata de una unidad de análisis estético-política que funciona como marco teórico para una morfología de lo social en tanto analítica del orden de lo sensible.; Both, be it the advance of electronic media and teletransmissions in the 20th century and the cyber digitalization of the 21st century, the various epistemic fields have been responsible for problematizing the relationship between the perceptive, the aesthetic (space-time) and the technological changes that impose new intersubjective practices, behaviors and modes of subjectivation. A specific concept arises in many authors: the sensorium. Whether a cultural approach or a specifically epistemological perspective is proposed, a reference to that category is often repeated in relation to changes in the speed and acceleration of images, texts and communications; first in the era of analog electronics and then in the digital age. The objective of this paper is to expose a brief systematization of the sensorium towards a possible definition as an aesthetic-political unit of analysis. This category let us think, on the one hand, about the Aesthetic discipline as political thought, and on the other, about politics in aesthetic terms. For this, this paper reviews various senses that the category of sensorium has had throughout history, according to its emergence in different epistemes. The first part identifies certain discourses locating authors in which specific uses can be found (Newton, Simmel, Benjamin, McLuhan, Kittler, etc.), thus it is possible to delineate a series of senses related to time and space from an aesthetic point of view, from the perception, social realm and the technique. Henceforth, the second part presents the idea of a “sensory turn” in contemporary social and political studies, where the idea of sensorium takes a new importance. Finally, the text focuses on the conceptual relationships that derive from Rancière's use of the category. Based on this lines, this paper seeks to delineate a series of elements to open the possibility of defining the Aesthetic as the thought of the common sensorium; as a unit of aesthetic-political analysis that works as a theoretical framework for a morphology of the social dimension, as analytical of the sensible order.

“El más extraño pensamiento”. Sobre algunas lecturas marxistas del Quijote; “The strangest thought”. On some Marxist readings of Quixote Vedda, Miguel Angel El artículo se ocupa de analizar algunas interpretaciones marxistas del Quijote de Cervantes. Se concentra, ante todo, en las lecturas realizadas por Ernst Bloch (en Espíritu de la Utopía y El principio esperanza) y György Lukács (Teoría de la novela y el ensayo “Don Quijote”), y pone las diferentes interpretaciones en relación con el pensamiento filosófico de ambos autores en sus respectivos períodos.; The article analyzes some Marxist interpretations of Cervantes’ Don Quixote. It focuses on the readings made by Ernst Bloch (in Spirit of Utopia and The Principle of Hope) and György Lukács (The Theory of the novel and the essay Don Quixote), and puts the different interpretations in relation to the philosophical thinking of both authors in their respective periods.