Polypropylene nanocomposites produced by in situ grafting of n-butyl acrylate Merchan Sandoval, Julie Pauline; Quinzani, Lidia Maria; Failla, Marcelo Daniel Nanocomposites of polypropylene and organophilic clay are produced by in situ functionalization of PP with n-butyl acrylate(BA) during melt mixing. Three strategies for incorporating materials into the mixer are analyzed and the effect of clay concentrationis evaluated. The materials are examined by FTIR spectroscopy, X-ray diffraction, scanning electron microscopy, differentialscanning calorimetry, thermogravimetry, and rotational rheometry. The results show that all composites prepared in the presence of BAhave similar intercalated clay structure, and that the largest degree of exfoliation is obtained using the sequential mixing technique. Thismethod, which consists in adding the initiator and functionalizing agent to the molten polypropylene followed by the addition of theclay, also produces the largest reduction in molecular weight of the polymer and the largest increase of the elastic modulus. All polymersshow similar crystallization and degradation processes.

Polymorphisms in TNF and IFNG are associated with clinical characteristics of aplastic anemia in Argentinean population Bestach, Yesica Soledad; Sieza, Yamila; Attie, Myriam; Riccheri, Cecilia; Verri, Verónica; Bolesina, Moira; Bengió, Raquel; Larripa, Irene Beatriz; Belli, Carolina Bárbara The impaired hematopoiesis in acquired aplastic anemia (AA) results from immune-mediated mechanisms. We characterized polymorphisms implicated in controlling type-1 cytokine production in 69 patients with AA. Our data suggest that the studied polymorphisms are not associated with susceptibility in the overall AA population. However, the presence of the higher expressing TNF - 308A allele was associated with younger age (p = 0.0297) and more profound neutropenia (p = 0.0312), and over-represented in patients with very severe AA (p = 0.0168). The higher producing IFNG 12 CA-repeat allele showed strong linkage disequilibrium with the + 874T allele, and was associated with a lower hemoglobin level (p = 0.0351). Also, the presence of at least one higher expressing variant was more frequent among patients responding to immunosuppressive treatment (p = 0.0519). Our findings suggest that the presence of higher expressing variants of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in AA patient genotypes could be related to clinical parameters, disease severity and therapy outcomes.

Stimulation of PAR-1 or PAR-4 promotes similar pattern of VEGF and endostatin release and pro-angiogenic responses mediated by human platelets Etulain, Julia; Mena, Hebe Agustina; Negrotto, Soledad; Schattner, Mirta Ana Background: Platelets mediate angiogenesis through the secretion of several factors, including the pro-angiogenic vascular endothelial growth factor (VEGF) and the anti-angiogenic endostatin. Although previous findings indicated that these molecules are packed into different alpha-granules and selectively released by specific stimulation of protease-activated receptor (PAR)-1 or PAR-4, recent evidences are against this hypothesis. Objectives: To elucidate the controversies about the VEGF and endostatin release and the overall angiogenic effect of PARs-stimulated platelets. Methods: VEGF and endostatin were quantified by enzyme linked-immunosorbent assay (ELISA). Endothelial proliferation (pNPP assay), wound healing (scratch assay) and tubule formation (matrigel) of human microvascular endothelial cells (HMEC-1) and endothelial progenitor cells (EPC) were determined using supernatants from PAR-1- or PAR-4-stimulated platelets. Results: Activation of washed platelets (WPs) by PAR-1- or PAR-4-activating peptide (AP) promoted the VEGF and endostatin secretion in a concentration-dependent manner, being PAR-1-AP more potent than PAR-4-AP. The release of both molecules was abrogated by pre-incubation of platelets with PAR antagonists. Activation of platelet-rich plasma (PRP) with either PAR-1-AP or PAR-4-AP induced a significant VEGF secretion. Quantification of platelet-endostatin secretion was not possible in PRP due to the high levels of plasmatic endostatin vs. platelet content. Releasates from PAR-1- or PAR-4-activated WPs promoted similar pattern of angiogenic responses of HMEC-1 or EPC. Moreover, proliferation of HMEC-1 mediated by PAR-stimulated PRP releasates was delayed and significantly lower compared with that induced by PAR-stimulated WPs. Conclusions: Our results are in contrast with the previously described differential release of VEGF and endostatin induced by the selective PAR-1 or PAR-4 stimulation, and support the notion that while circulating endostatin accounts for the maintenance of a systemic anti-angiogenic state, locally, the release of platelet alpha-granule content promotes angiogenesis.

Structural, conformational and vibrational properties of 1,1,1-Trifluoro-N-(1,1,2,2,2-pentafluoroethyl) methanesulfinimidoyl chloride, CF3CF2NS(Cl)CF3 Robles, Norma Lis; Chemes, Doly María; Heinz Oberhammer; Cutin, Edgardo Hugo The structural, conformational, and configurational properties of 1,1,1-Trifluoro-N-(1,1,2,2,2-pentafluoroethyl) methanesulfinimidoyl chloride, CF3CF2NS(Cl)CF3 have been studied by vibrational spectroscopy [IR (vapor) and Raman (liquid)] and quantum chemical calculations [B3LYP, MP2 and B3PW91 levels of theory using the 6-311+G(d), 6-311+G(df) and 6-311+G(2df) basis sets]. According to these theoretical approximations, CF3CF2NS(Cl)CF3 exists in the gas phase as a mixture of a favored anticlinal form (CN bond anticlinal with respect to the CSCl bisector) with C1 symmetry and a less abundant syn conformer showing C1 symmetry as well (ΔG° ≈ 1.20 kcal mol-1). Due to the small contribution only a few corresponding vibrational modes of the syn conformer could be assigned confidently in the experimental spectra. Compared to CF3CF2NS(F)CF3, the replacement of F by Cl produces a clear change in NS bond length and the corresponding stretching frequency, without affecting the conformational properties.

A Steady-State Picture of Solar Wind Acceleration and Charge State Composition Derived from a Global Wave-Driven MHD Model Oran, R.; Landi, E.; Van Der Holst, B.; Lepri, S. T.; Vasquez, Alberto Marcos; Nuevo, Federico Alberto; Frazin, R.; Manchester, W.; Sokolov, I.; Gombosi, T. I. The higher charge states found in slow (<400 km s−1) solar wind streams compared to fast streams have supported the hypothesis that the slow wind originates in closed coronal loops, and released intermittently through reconnection. Here we examine whether a highly ionized slow wind can also form along steady and open magnetic field lines. We model the steady-state solar atmosphere using AWSoM, a global magnetohydrodynamic model driven by Alfv{´e}n waves, and apply an ionization code to calculate the charge state evolution along modeled open field lines. This constitutes the first charge states calculation covering all latitudes in a realistic magnetic field. The ratios $O^{+7}/O^{+6}$ and $C^{+6}/C^{+5}$ are compared to in-situ Ulysses observations, and are found to be higher in the slow wind, as observed; however, they are under-predicted in both wind types. The modeled ion fractions of S, Si, and Fe are used to calculate line-of-sight intensities, which are compared to EIS observations above a coronal hole. The agreement is partial, and suggests that all ionization rates are under-predicted. Assuming the presence of suprathermal electrons improved the agreement with both EIS and Ulysses observations; importantly, the trend of higher ionization in the slow wind was maintained. The results suggest there can be a sub-class of slow wind that is steady and highly ionized. Further analysis shows it originates from coronal hole boundaries (CHB), where the modeled electron density and temperature are higher than inside the hole, leading to faster ionization. This property of CHBs is global, and observationally supported by EUV tomography.

Mitochondrial dysfunction in skeletal muscle during experimental Chagas disease Báez, Alejandra Lidia; Reynoso, Mercedes María Noel; Lo Presti, Maria Silvina; Bazán, Paola Carolina; Strauss, Mariana; Miler, Noemí del Carmen; Pons, Patricia; Rivarola, Hector Walter; Paglini, Patricia Adriana Trypanosoma cruzi invasion and replication in cardiomyocytes and other tissues induce cellular injuries and cytotoxic reactions, with the production of inflammatory cytokines and nitric oxide, both sources of reactive oxygen species. The myocyte response to oxidative stress involves the progression of cellular changes primarily targeting mitochondria. Similar alterations could be taking place in mitochondria from the skeletal muscle; if that is the case, a simple skeletal muscle biopsy would give information about the cardiac energetic production that could be used as a predictor of the chagasic cardiopathy evolution. Therefore, in the present paper we studied skeletal muscle mitochondrial structure and the enzymatic activity of citrate synthase and respiratory chain complexes I to IV (CI–CIV), in Albino Swiss mice infected with T. cruzi, Tulahuen strain and SGO Z12 and Lucky isolates, along the infection. Changes in the mitochondrial structure were detected in 100% of the mitochondria analyzed from the infected groups: they all presented at least 1 significant abnormality such as increase in their matrix or disorganization of their cristae, which are probably related to the enzymatic dysfunction. When we studied the Krebs cycle functionality through the measurement of the specific citrate synthase activity, we found it to be significantly diminished during the acute phase of the infection in Tulahuen and SGO Z12 infected groups with respect to the control one; citrate synthase activity from the Lucky group was significantly increased (p b 0.05). The activity of this enzyme was reduced in all the infected groups during the chronic asymptomatic phase (p b 0.001) and return to normal values (Tulahuen and SGO Z12) or increased its activity (Lucky) by day 365 post-infection (p.i.). When the mitochondrial respiratory chain was analyzed from the acute to the chronic phase of the infection through the measurement of the activity of complexes I to IV, the activity of CI remained similar to control in Tulahuen and Lucky groups, but was significantly augmented in the SGO Z12 one in the acute and chronic phases (p b 0.05). CII increased its activity in Tulahuen and Lucky groups by day 75 p.i. and in SGO Z12 by day 365 p.i. (p b 0.05). CIII showed a similar behavior in the 3 infected groups, remaining similar to control values in the first two stages of the infection and significantly increasing later on (p b 0.0001). CIV showed an increase in its activity in Lucky throughout all stages of infection (p b 0.0001) and an increase in Tulahuen by day 365 days p.i. (p b 0.0001); SGO Z12 on the other hand, showed a decreased CIV activity at the same time. The structural changes in skeletal muscle mitochondria and their altered enzyme activity began in the acute phase of infection, probably modifying the ability of mitochondria to generate energy; these changes were not compensated in the rest of the phases of the infection. Chagas is a systemic disease, which produces not only heart damage but also permanent skeletal muscle alterations.

El regreso de los militares veteranos de guerra de Malvinas a la Armada: entre el ocultamiento, el silencio y el aislamiento. El caso de los marinos del Apostadero Naval Malvinas Rodríguez, Andrea Belén El artículo aborda la inmediata posguerra de los integrantes el Apostadero Naval Malvinas –una unidad logística naval– durante el Conflicto del Atlántico Sur. En concreto, analiza las experiencias de regreso a la Armada de los cabos, suboficiales y oficiales que integraron ese destino, al tiempo que reconstruye las políticas implementadas por la fuerza en la recepción y reinserción de quienes habían combatido. Parte de la hipótesis que en un contexto de profundo desprestigio militar, el silencio, ocultamiento y aislamiento de los veteranos de guerra fue lo que primó al interior de la Marina con el objeto de tratar de combatir los múltiples conflictos que estallaron con la derrota militar, producto no sólo de las responsabilidades de la guerra en las islas sino también de las violaciones a los DD.HH. que las FF.AA. habían cometido en los ‘70.; The article is about the immediate postwar of the sailors that served in the Apostadero Naval Malvinas –a naval logistics unit– during the South Atlantic Conflict. In particular, it analyzes the experiences of return to the Navy of the corporal, non-commissioned officers and officers that had served this destination, while reconstructs the policies implemented by the naval force at the reception and reintegration of those who had fought. This paper is based on the hypothesis that in a context of deep military discredit., silence, secrecy and isolation of war veterans was what prevailed in the Marine in order to try to fight the many conflicts that appeared after the defeat, product not only of the war responsibilities but also of the violations of humans rights that the military had committed in the ‘70s.

El desarrollo y la colonialidad del poder: análisis de dos experiencias agroecológicas de la provincia del Chaco Pegoraro, María Laura Durante los últimos setenta años, el desarrollo como idea fuerza extendió la hegemonía del capitalismo, potenciando la producción y reproducción de sus lógicas en múltiples dimensiones. Oculta así, bajo el signo de la libertad de elegir, de la incorporación social al mundo global y del acceso al bienestar vía el consumo, el proceso de dominación, explotación y conflicto necesario para la imposición del desarrollo a la manera occidental desde el cual fue conceptualizado A pesar de ello, emergen, en el seno mismo del sistema, experiencias alternativas al capitalismo en las cuales el concepto de colonialidad del poder permite identificar las dimensiones que forman parte de dicho proceso de dominación, explotación y conflicto para el desarrollo económico y admite explorar cómo, desde la práctica, los actores adaptan estas dimensiones, las revierten o las superan. En este marco, en este trabajo** indagaremos el proceso productivo, de organización y de interacción en dos cooperativas agroecológicas chaqueñas. Las experiencias concretas, analizadas en una investigación exploratoria cualitativa con anclaje etnográfico, traslucen lógicas alternativas a las capitalistas en algunas dimensiones, pero también similares en otras. La naturaleza no se presenta únicamente como un factor de la producción, siendo el individuo parte de la misma. Lo ambiental se mezcla con lo político, y el conocimiento experto-científico se entrecruza con los saberes de los campesinos-indígenas en la producción. La inserción en el mercado y la definición de los precios carga las ?racionalidades? capitalistas. Las lógicas modernas-capitalistas se cuelan con otras, y se construyen y redefinen. Su importancia radica en que permiten mirar desde un lugar distinto a la modernidad, y reclaman un entendimiento diferente dentro de las ciencias sociales.; Over the past 70 years, the development as a powerful-idea spread out the hegemony of capitalism, promoting the production and reproduction of their logic in multiple dimensions. It hides the process of domination, exploitation and conflict, which is necessary for the imposition of the development on Western stile. It was conceptualized under the sign of freedom of choice, the social inclusion in the global world and the access to welfare by consumption. However, alternative experiences to the capitalism emerge within the system, where the concept of coloniality of power identifies the dimensions that are part of the process of domination, exploitation and conflict for the economic development itself, and admits to explore how actors adapt these dimensions from the practice, reverse them or overcome them. In this framework we will investigate the production process of organization and interaction in two agro-ecological cooperatives in Chaco. The specific experiences, analyzed in a qualitative exploratory research with ethnographically-anchor, show logical alternatives to the capitalist ones in some dimensions, but also similar in others. Nature does not seem to be a production factor, and the human being is part of it. The environment is mixed with politics, and the expert-scientific knowledge intersects with peasant-indigenous knowledge in the production. The fact of inserting in the market and the price definition carries with the capitalists "rationality". The modern-capitalist logics mix with others, and are built and redefined. Its importance lies in that they allow to look from a different place to modernity and demand a different understanding within the social sciences.

¿Pueden las técnicas de mitigación de estrés ambiental mejorar la supervivencia y el crecimiento de plantines de coníferas en el N.O. de la Patagonia? Varela Santiago; Gyenge, Javier Enrique; Diez, Juan Pablo; Weigandt, Mariana Noemi; Caballe, Gonzalo Las etapas iniciales de vida de los árboles son particularmente susceptibles a condiciones de estrés ambiental y eventos extremos. El desarrollo de estrategias de mitigación durante etapas tempranas parece ser un factor determinante para la supervivencia en hábitats con estas condiciones, las cuales, en base a pronósticos climáticos, se predice que serán aún más severas que en la actualidad.

Drugs affecting blood pressure variability: an update Höcht, Christian; del Mauro, Julieta Sofía; Bertera, Facundo Martin; Taira, Carlos Alberto Blood pressure variability (BPV) is considered nowadays a novel risk factor for cardiovascular disease. Clinical evidences support that short-term and long-term BPV independently contribute to target organ damage, cardiovascular events and mortality in patients with hypertension or diabetes. Attenuation of excessive fluctuations of systolic and diastolic BPV has been suggested as an additional therapeutic target in cardiovascular prevention. A growing number of preclinical and clinical studies have focused in the assessment of drug effects or other interventions on the different types of BPV and their contribution in the prevention of cardiovascular events. Prospective clinical trials have shown that antihypertensive classes differ in their ability to control excessive BP fluctuations with an impact in clinical outcomes. Current evidences suggest that calcium channel blockers are more effective than other blood pressure lowering drugs for the reduction of short-term, mid-term and long-term BPV. In order to increase actual knowledge regarding the therapeutic significance of BPV in cardiovascular disease, there is a need for additional clinical studies specifically designed for the study of the relevance of short-term and long-term BPV control by antihypertensive drugs

Exploring the Dynamics of Cell Processes through Simulations of Fluorescence Microscopy Experiments Angiolini, Juan Francisco; Plachta, Nicolas Daniel; Mocskos, Esteban Eduardo; Levi, Valeria Fluorescence correlation spectroscopy (FCS) methods are powerful tools for unveiling the dynamical organization of cells. For simple cases, such as molecules passively moving in a homogeneous media, FCS analysis yields analytical functions that can be fitted to the experimental data to recover the phenomenological rate parameters. Unfortunately, many dynamical processes in cells do not follow these simple models, and in many instances it is not possible to obtain an analytical function through a theoretical analysis of a more complex model. In such cases, experimental analysis can be combined with Monte Carlo simulations to aid in interpretation of the data. In response to this need, we developed a method called FERNET (Fluorescence Emission Recipes and Numerical routines Toolkit) based on Monte Carlo simulations and the MCell-Blender platform, which was designed to treat the reaction-diffusion problem under realistic scenarios. This method enables us to set complex geometries of the simulation space, distribute molecules among different compartments, and define interspecies reactions with selected kinetic constants, diffusion coefficients, and species brightness. We apply this method to simulate single- and multiple-point FCS, photon-counting histogram analysis, raster image correlation spectroscopy, and two-color fluorescence cross-correlation spectroscopy. We believe that this new program could be very useful for predicting and understanding the output of fluorescence microscopy experiments.

Identification and evaluation of new Mycobacterium bovis antigens in the in vitro interferon gamma release assay for bovine tuberculosis diagnosis Eirin, Maria Emilia; Macías, Analia Florencia; Magnano, Gabriel Gustavo; Morsella, Claudia; Mendez, Laura; Blanco, Federico Carlos; Bianco, María Verónica; Severina, Walter; Alito, Alicia; Pando, María de los Ángeles; Singh, Mahavir; Spallek, Ralph; Paolicchi, Fernando Alberto; Bigi, Fabiana; Cataldi, Ángel Adrián Bovine tuberculosis (bTB) is a common zoonotic disease, caused by Mycobacterium bovis (M. bovis),responsible for significant economic losses worldwide. Its diagnosis is based on the detection of cellmediated immunity under the exposure to protein purified derivative tuberculin (PPD), a complex andpoorly characterized reagent. The cross-reactivity to non-tuberculous mycobacterium species (falsepositiveresults) has been crucial to develop a more proper antigen. In the present study, we selected sixM. bovis Open Reading Frames (Mb1992, Mb2031c, Mb2319, Mb2843c, Mb2845c and Mb3212c) by insilicoanalysis and evaluated them in experimental and natural infection; none of these antigens hadbeen previously assessed as diagnostic antigens for bTB. The reactivity performance was tested in animalswith both positive and negative Tuberculin Skin Test (TST) results as well as in cattle infected withMycobacterium avium subesp. paratuberculosis (MAP). The six recombinant antigens individually inducedan IFN-g response, with overall responder frequency ranging from 18.3 to 31%. Mb2845c was the mostvaluable antigen with the potential to discriminate TST-positive cattle from either TST-negative or MAPinfected animals. Mb2845c showed similar performance to that observed with ESAT-6 and PPD-B amongTST and MTC specific-PCR positive animals, although this result needs to be proven in further studieswith a higher sample size. Our data confirm the feacibility to implement bioinformatic screening toolsand suggest Mb2845c as a potential diagnostic antigen to be tested in protein cocktails to evaluate theircontribution to bTB diagnosis.

Universidad y producción de conocimiento orientado a la política criminal. Un estudio de caso; University and knowledge production oriented to criminology policy. A case study Avila, Javier Guillermo; Estébanez, María Elina Se presentan resultados parciales de una investigación en curso que analiza la producción de conocimiento criminológico en el ámbito universitario público argentino desde la perspectiva del campo CTS. El foco principal de interés es la caracterización de las formas de vinculación entre actores científicos y no científicos durante las prácticas de producción de conocimiento, y la detección de fenómenos de co-producción, discutido en la literatura como uno de los factores que estimula la aplicación y uso social de resultados de la I+D. Para abordar este tema, se seleccionaron cuatro grupos de investigación localizados en una provincia argentina, e integrantes a su vez de una red multidisciplinaria de grupos universitarios financiada con fondos públicos y dedicada a estudiar el problema de la seguridad, el delito y las respuestas del Estado y las políticas públicas en el país. Estos grupos fueron analizados bajo una metodología de análisis de redes sociales, con el fin de modelizar los patrones de interacción observados entre los investigadores y otros actores sociales en diversas instancias del desarrollo de sus investigaciones. Se discuten los resultados obtenidos en el cálculo de indicadores relacionales de centralidad, centralización e intermediación derivados del análisis de redes.; This article presents partial results of a research in course that analyzes the production of criminological knowledge in an argentine public university from the perspective of the STS studies. The main focus of interest is the characterization of linkages types between scientist and no scientist during the practices of knowledge production, and the detection of phenomena of co-production, discussed in the literature as one of the factors that stimulates the application and social use of the R&D results. To address this issue, it was selected four research groups located in a province of Argentina, that take part of a multidisciplinary network of university groups funded with public funds and dedicated to study the problem of security, crime and the responses of the State and public policies in the country. These groups were analyzed under a methodology of social networks analysis of, in order to model the interaction patterns observed between researchers and other stakeholders in different instances of the development of their research. It is discussed some results obtained in the calculation of relational indicators of centrality, centralization and intermediations arising from network analysis.

Frente al límite del enfoque de derechos: la educación como política de prevención social del riesgo; Regarding the limit to rights approach: Education as a social risk prevention policy Pereyra, Ana; Guemureman, Silvia Teresa El artículo señala la confluencia entre los marcos conceptuales que organizaron las políticas educativas de las últimas décadas centradas en la noción de inclusión con aquellos destinados a los sectores más vulnerables de la población conocidos como políticas de gestión social del riesgo. Se analizan las tendencias recientes de la educación argentina y su relación con políticas públicas como la Asignación Universal por Hijo y políticas socio- educativas como Conectar Igualdad y Plan FINES. Se propo-ne una hipótesis en torno a las dificultades de la escuela para alcanzar la inclusión en los aprendizajes, compatibilizando dos principios en apariencia contradictorios como son la inclusión y las competencias. Posteriormente, se abordan los conceptos de riesgo y prevención como organizadores de otras “políticas sociales” orientadas a sectores vulnerables. Finalmente se des-taca que en las prácticas institucionales el enfoque inclusivo no logró dar preeminencia a la construcción de los lazos sociales inherentes a la ciudadanía y que la lógica del enfoque de dere-chos se mantuvo en el plano de las competencias ligadas a la inserción – jerárquica y diferencial- en el mercado laboral.; This article points out the confluence between the conceptual framewor-ks that organized the educational policies of the last decades focused on the notion of inclusion and those aimed at the most vulnerable sectors of the population known as policies of social risk management.Firstly, the recent trends in education in Argentina are analyzed. Thus, this article is then particularly concerned with social and educational policies as “Asignación Universal por Hijo” (Universal Child Allowance), “Conectar Igualdad” and “Plan FINES”. In a third stage, a hypothesis is proposed around the school difficulties to achieve inclusion in learning. This hypothesis focuses between two apparently contradictory principles such as inclusion and skills. In a fourth stage, this article focuses on the concepts of risk and prevention as organizers of other “social policies” aimed at vulnerable sectors. Findings highlight that inclusive approach has failed in terms of institutional practices to give prominence to the construction of social ties inherent to citizenship and that the logic of rights approach has remained as regards skills linked to the - hierarchical and differential- integration into the labor market.

Cambio estructural y desarrollo: Eficiencia keynesiana y shumpeteriana en la industria manufacturera en la Argentina en el período 2003-2011 Rivas, Diego; Robert, Veronica El presente documento tiene como objetivo caracterizar al proceso de crecimiento argentino durante el período 2003-2011 atendiendo especialmente a la dinámica del sector industrial, los cambios en su composición y el impacto de dichas trasformaciones en el mundo del trabajo (empleo, salarios, formalidad). Distintos estudios han procurado caracterizar este período haciendo hincapié en el desempeño de la industria manufacturera. Estos trabajos pueden agruparse en dos categorías: (i) los que analizan el impacto social del crecimiento económico (Peirano y otros, 2010; Lavopa, 2007; Cenda, 2010; Azpiazu y Schorr, 2010; Coatz y otros, 2011); y (ii) los que discuten la presencia o no de cambio estructural (Santarcángelo y otros, 2011; Fernández Bugna y Porta, 2008, Basualdo y otros, 2010; Roitter y otros, 2012). Se vislumbran dos consensos centrales en esta literatura: i) que en el período bajo análisis se registró una expansión importante en las actividades industriales intensivas en empleo, permitiendo la recomposición del empleo industrial en la Argentina; y (ii) que los rasgos generales de la estructura productiva —una especialización en actividades de bajo contenido tecnológico y menor complejidad relativa— tendieron a reproducirse más allá de algunas transformaciones marginales definidas por las trayectorias sectoriales específicas. En este documento buscamos contribuir a este debate profundizando la discusión acerca de la relación entre la dinámica tecnológica, la estructura productiva y su vinculación con la dinámica social. Para ello intentamos operacionalizar el siguiente interrogante: ¿el crecimiento de la economía argentina entre 2003 y 2011 estuvo asociado a una transformación basada en una mayor eficiencia dinámica, en la que la expansión de la oferta se retroalimenta con la expansión de la demanda y la difusión tecnológica, o estuvo basado en la eficiencia estática, asociada a la explotación de recursos naturales, sin mayor relación con el lado de la demanda interna ni vinculaciones sinérgicas con el resto del aparato productivo?

Ilegalismos, conflictos y prácticas de seguridad en la aplicación del Programa Comunidades Vulnerables; Ilegalities, conflicts and safety practices during the implementation of “Programa de Comunidades Vulnerables” Mancini, Inés María Este trabajo analiza un aspecto particular de la relación entre agentes estatales y jóvenes de sectores populares a partir de la aplicación de una política territorial. Nos referiremos a los modos en los que las formas de violencia urbana intervienen en el trabajo concreto de un programa que justamente busca prevenir la producción de delitos. Para ello analizaremos, a) los modos en los que la violencia y los delitos que pueden tener lugar en el contexto de una villa de emergencia afectan a los agentes de aplicación de esta política y b) los modos en los que los jóvenes beneficiarios interpretan y relatan hechos de violencia que tienen lugar en el barrio o en la ciudad (ya sean cometidos por ellos o por otros) y los efectos que estos relatos tienen en la relación con los agentes estatales.; This paper examines a particular aspect of the relationship between state actors and young people from popular sectors from the application of a territorial policy. We will refer to the ways in which forms of urban violence involved in the actual work of a program that seeks to prevent precisely the production of crime. We will analyze a) the ways in which violence and crimes that may occur in the context of a shanty-town affect implementation of this policy and b) the ways in which reports of violence are interpretated by state agents.

Indigenous Agency and Written Culture in the Jesuit Missions of Paraguay Wilde, Guillermo Luis Recent research has paid special attentionto the role played by indigenous elite in the production of texts and maps. Thediscovery of a large number of manuscripts made by indigenous authorities indifferent media and for diverse purposes, from council documents to personal accounts,calls into question old assumptions about indigenous passivity in the JesuitMissions. Evidence indicates that the skill of writing was important in the missions daily life, and that its practice was widespread among members of the indigenouselite. This article briefly explores some examples.

El debate sobre la supervisión financiera integrada: ¿Qué hay de nuevo?; The Debate on Integrated Financial Supervision: What is New? Demaestri, Edgardo; Ferro, Gustavo Adolfo Este trabajo discute la supervisión integrada de diferentes tipos de intermediarios financieros. Razones de estabilidad sistémica, protección al consumidor no sofisticado y promoción de la eficiencia del sistema justifican la regulación prudencial y de conducta teniendo en cuenta las fallas de los mercados financieros, generalmente de naturaleza informativa. Se debaten los argumentos a favor y en contra de la integración de la supervisión, el rol del banco central en la supervisión financiera y la discusión posterior a la crisis de 2008. Se revisa y analiza la literatura conceptual y empírica. Se presentan los consensos.; This article discusses the integrated financial supervision of different kinds of financial intermediaries. Systemic stability, non-sophisticated consumers protection and the efficiency enhancement have been advanced as explanations of prudential and conduct regulation. These are founded on financial markets failures, mainly because of asymmetric information. We debate pros and cons of integrating supervision, the role of the central bank in the financial supervision, and the more recent discussion in the aftermath of the 2008 financial crisis. We review and analyze the conceptual and empirical literature, and present the current consensus.

El rol de la banca pública en el financiamiento a PyMEs: Estudio comparativo para la Argentina y Brasil; The Role of public banks in financing SMEs: Comparative study for Argentina and Brazil Villar, Luciana; Briozzo, Anahi Eugenia; Pesce, Gabriela; Fernández, Andrea El objetivo de este artículo es estudiar a nivel de empresa el rol de la banca pública como atenuador de fallas de mercado e instrumento de desarrollo. Se analizan características diferenciales de las pequeñas y medianas empresas (pymes) en relación con su financiamiento a través de las bancas privada y pública, en forma comparada para la Argentina y Brasil. Los datos empleados provienen de la base World Enterprise Surveys del Banco Mundial. Los resultados se alinean con lo esperado y se observa que las empresas de menor tamaño tienen mayor probabilidad de tener créditos en la banca pública. Entre los resultados diferenciales entre países se destaca que en la Argentina incide negativamente pertenecer al sector industrial y tener un mayor porcentaje de las ventas dedicadas al mercado nacional, mientras que en Brasil hay un efecto negativo cuando la empresa es dirigida por una mujer.; The aim of this paper is to study at firm level the role of public banking as an attenuator of market failures and as development instrument. We analyze the differential characteristics of small and medium enterprises in relation to their funding through private and public banks, comparing Argentina and Brazil. We use the World Bank Enterprise Surveys database. The results are in line with expectations, showing that smaller companies are more likely to have loans in public banks. As differential results between countries, in Argentina the variables that show a negative effect are belonging to the industrial sector, and having a higher percentage of sales devoted to the domestic market. In contrast, in Brazil it adversely affects that the company director is a woman.

Daniel Moyano, archivo y experiencia de escritura Casarin, Marcelo; Vigna, Diego Germán El archivo del escritor argentino Daniel Moyano (Buenos Aires, 1930-Madrid, 1992) comenzó a conocerse en 2009, cuando un grupo de investigadores con el apoyo del Centre de Recherches Latino-américaines / Archivos de la Université de Poitiers accedió a la casa en la que el autor pasó sus últimos años, en la ciudad de Madrid. Allí se exploró un tesoro escondido para el mundo académico y cultural por casi 17 años. La obra de Moyano se distingue por una potencia creativa de múltiples aristas, que con todas sus riquezas y curiosidades ha sido el resultado de un singular recorrido experiencial, nutrido de muchos oficios. Moyano ha sido un escritor descolocado, en varios sentidos; fuera de lugar por las diversas experiencias de exilio y desarraigo que le tocaron vivir, y por lugares simbólicos que ocupó y dejó en relación al mercado editorial y por tanto al público. Los archivos de escritores son valiosos porque propician el diálogo entre obras publicadas y aquellos aspectos del trabajo que permanecen ocultos en la intimidad. Contienen información clave de la génesis de los textos bajo la forma de borradores, manuscritos, dactiloscritos, versiones digitales que permiten asistir a las vacilaciones del proceso de escritura de una obra en particular o de un conjunto de obras. Pero también suelen reunir otros documentos que dan cuenta de la vida civil y personal de los escritores, que testifican su paso por el mundo y los conectan de modo singular con su tiempo.; The archive of Argentine writer Daniel Moyano (Buenos Aires, 1930-Madrid, 1992) became known in 2009, when a group of researchers supported by the Centre de Recherches Latino-américaines / Archivos (Université de Poitiers) accessed the house in Madrid where the author spent his last years,. They explored a treasure that had been hidden from academic and cultural world for over 17 years. Moyano’s work is distinguished by a creative power of multiple edges, and with wealth and curiosities, it is the result of a singular experiential itinerary, nurtured by many trades. Moyano has been a dislocated writer in many ways. Misplaced by the diverse experiences of exile that he have lived, and by symbolic places which he occupied and left related with the publishing market and, therefore, with the public. The writers’ archives are valuable because they favor the dialogue between works already published and those aspects of the work that remain hidden in privacy. They contain information of the genesis of texts, in the form of drafts, manuscripts, digital versions, etc., showing the vacillations of the writing process from a particular work or a set of works. But usually there are other documents that account for the writer›s civil and personal life, which testify their passage through the world and connecting them in a singular way with their time.