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Descripción de tres casos del síndrome de oreja caída en bovinos

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Descripción de tres casos del síndrome de oreja caída en bovinos Magnano, Gabriel Gustavo; Mació, Mauro Nahuel; Bagnis, Guillermo; Macías, Analia Florencia; Sticotti, Erika Elizabeth; Redondo, Enzo Alejandro; Schneider, Manuel Oscar; Fernández, Julián; Barberis, Carla Lorena; Ramirez, Maria Laura; Giraudo, José El síndrome conocido como "oreja caída" es un hallazgo clínico observado en los sistemas productivos bovinos. Varias son las etiologías descriptas como causa de esa patología. El objetivo del presente trabajo es describir tres casos de oreja caída en bovinos.Se estudiaron dos casos en engorde a corral y uno en guachera. Se realizaron exámenes clínicos, necropsias, histopatologías y diferentes técnicas entre ellas cultivo de hongos, de bacterias, de virus, etc. En todos los animales necropsiados se observó aumento de tamaño del ganglio de Gasser. En los estudios histopatológicos se encontró reacción granulomatosa y presencia de estructuras compatibles con criptococos que fueron positivas a la tinción de PAS. El aislamiento y tipificación de Cryptococcus neoformans de 1 animal, los resultados de los exámenes anatomo-histopatológicos, y las características estructurales y tintoriales observadas en todos los casos indican un diagnóstico compatible con criptococosis nerviosa.

Modos de producir, comercializar y consumir en tiempos de crisis alimentaria: el caso de la feria agroecológica de Córdoba

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Modos de producir, comercializar y consumir en tiempos de crisis alimentaria: el caso de la feria agroecológica de Córdoba; Ways of producing, marketing and consuming in times of food crisis: the case of the agroecological fair in córdoba Seplovich, Julieta La aplicación de modelos económicos neoliberales en América Latina y en particular en Argentina ha constituido una herramienta fundamental para la implementación de un modelo de desarrollo agropecuario centrado en las ganancias con fuertes consecuencias ambientales donde los alimentos tienen otros destinos diferentes al de alimentar y contribuir a la reproducción social de los sujetos, hecho que se evidencia en las múltiples intervenciones que estuvieron dirigidas a ?combatir el hambre? y fracasaron a lo largo del tiempo. El objetivo de este artículo es historizar la conformación de la primera Feria Agroecológica de Córdoba (FAC) y analizar aquellos aspectos que reivindican y recrean otras maneras de alimentar(nos). Los datos fueron obtenidos de observaciones participantes y grupos de discusión con informantes claves de la FAC y analizados a partir de la teoría fundamentada. Se argumenta que la FAC constituye una forma novedosa de articulación campo-ciudad: se revalorizan formas de producir los alimentos diferentes a las del agronegocio; se tienden puentes directos entre productores y consumidores problematizados por el origen y la composición de sus alimentos y se generan instancias de aprendizaje en su encuentro cara a cara. Se concluye que es necesario masificar y politizar este tipo de experiencias a la vez que exigir al Estado políticas públicas que tiendan a construir sistemas alimentarios más democráticos.; The application of neoliberal economic models in Latin America and in particular in Argentina has been a fundamental tool for the implementation of a model of agricultural development centered on profits with strong environmental consequences where food has other destinations than that of feeding and contributing to the social reproduction of subjects, a fact that is evidenced in the multiple interventions that were aimed at "fighting hunger" and failed over time. The objective of this article is to historize the conformation of the first Agroecological Fair of Cordoba (Feria Agroecológica de Córdoba, FAC) and to analyze those aspects that claim and recreate other ways of feeding. The data were obtained from participating observations and discussion groups with key informants from the FAC, which were analyzed based on the grounded theory. It is argued that FAC constitutes a novel form of field-city articulation: ways of producing food different from agribusiness are revalued; direct bridges are built between producers and consumers problematized by the origin and composition of their food and learning instances are generated in their face-to-face encounter. It concludes that it is necessary to massify and politicize this type of experience while at the same time demanding from the State public policies that tend to build more democratic food systems.

Caracterización de agregados pétreos de las Sierras Septentrionales de la provincia de Buenos Aires

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Caracterización de agregados pétreos de las Sierras Septentrionales de la provincia de Buenos Aires Pérez Marfil, P.; Priano, C.; Locati, Francisco; Marfil, S. En este estudio se realizaron diferentes ensayos físicos en triturados pétreos de canteras ubicadas en las Sierras Septentrionales de la provincia de Buenos Aires. A fin de efectuar una evaluación integral del desempeño de esos agregados para su uso en hormigón, se compararon los resultados de los ensayos físicos con estudios petrográficos previos (IRAM 1649). Se evaluaron siete canteras ubicadas en cercanías a las ciudades de Olavarría, Azul y Balcarce. Se realizaron análisis de densidad a granel y espacios vacíos (IRAM 1548), densidad relativa real, aparente y absorción de agua (IRAM 1533), granulometría (IRAM 1505) y se determinó la resistencia a la fragmentación (IRAM 1532). Los agregados presentan en general buenas características físicas, sin embargo, es indispensable efectuar comparaciones con el análisis petrográfico del material, ya que un buendesempeño en determinadas propiedades físicas puede no significar un buen comportamiento frente a la reacción álcali-sílice.; In this study different physical characterization tests were performed in aggregates from quarries located in the Sierras Septentrionales of the province of Buenos Aires. In order to carry out a comprehensive evaluation of the performance of those aggregates for use in concrete, results of physical tests were compared with previous petrographic studies (IRAM 1649). Seven quarries located near Olavarría, Azul and Balcarce cities were evaluated. Bulk density and voids (IRAM 1548), relative real and apparent density, water absorption (IRAM 1533), granulometry (IRAM 1505) and fragmentation resistance (IRAM 1532) were determined. The aggregates generally present good physical characteristics; however, it is essential to compare with the petrographic analysis of the material, since a good performance in certain physical properties may not mean a good behaviour against alkali-silica reaction.

El espacio de Formación en Ambiente de Trabajo en escuelas técnicas de Córdoba: el mercado como agente regulador

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El espacio de Formación en Ambiente de Trabajo en escuelas técnicas de Córdoba: el mercado como agente regulador; Education in work environment for technical schools of Córdoba: the market as a regulator agent Bocchio, María Cecilia; Maturo, Yanina Débora La Formación en Ambiente de Trabajo (FAT) está enmarcada en la modalidad de Educación Técnico Profesional (ETP) de la escuela secundaria obligatoria. En este artículo recuperamos aportes del trabajo de campo desarrollado en dos escuelas técnicas de la ciudad de Córdoba, Argentina, donde la FAT tiene el formato de pasantía. Proponemos siguiendo los aportes de Barroso (2006) y Sarmento (2000) que cuando docentes y directivos ponen en acto la FAT construyen lógicas de acción que se traducen en prácticas y sentidos que dotan de un nuevo significado al espacio curricular. Planteamos, a modo de hipótesis, que la FAT se presenta como un espacio dentro de la escuela técnica donde se objetivan tanto las dinámicas internas –institucionalizadas por cada escuela, como las dinámicas externas –que intervienen en la articulación escuelamundo del trabajo– y, donde el mercado se configura en un agente regulador de la FAT.; Education in Work Environment (EWE) is framed in the modality of Educational Technical Education (ETE) of the compulsory secondary school. In this article we recover the contributions of fieldwork developed in two technical schools in the city of Córdoba, Argentina, where the EWE has the format of an internship. We propose following the contributions of Barroso (2006) and Sarmento (2000) that when teachers and principals enact the EWE, they construct logics of action that give a new meaning to the curriculum. We propose, as hypothesis, that EWE is presented as a space within the technical school where the internal institutional dynamics of each school is objectified, as well as the external dynamics, which intervenes in the articulation school- work world, and, where the market is configured as a regulatory agent of the EWE.

Role of suspension feeders in antarctic pelagic-benthic coupling: Trophic ecology and potential carbon sinks under climate change

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Role of suspension feeders in antarctic pelagic-benthic coupling: Trophic ecology and potential carbon sinks under climate change Alurralde, Roque Gastón; Fuentes, Verónica Lorena; Maggioni, Tamara; Movilla, Juancho; Olariaga, Alejandro; Orejas, Covadonga; Schloss, Irene Ruth; Tatián, Marcos Sea-ice and coastal glacier loss in the Western Antarctic Peninsula open new ice-free areas. They allowing primary production and providing new seabed for colonisation, both acting as a negative feedback of climate change. However, the injection of sediment-laden runoff from the melting of land-terminating glaciers may reduce this feedback. Changes in particulate matter will affect nutrition and excretion (faeces stoichiometry and properties) of suspension feeders, reshaping coastal carbon dynamics and pelagic-benthic coupling. Absorption efficiency and biodeposition of Euphausia superba and Cnemidocarpa verrucosa were quantified for different food treatments and varying sediment concentrations. Both species showed high overall absorption efficiency for free-sediment diets, but were negatively affected by sediment addition. High sediment conditions increased krill biodeposition, while it decreased in ascidians. Energy balance estimation indicated high carbon sink potential in ascidians, but it is modulated by food characteristics and negatively affected by sediment inputs in the water column.

Estrategias económicas y desigualdad social. Dinámicas de consumo, ahorro y finanzas de familias cordobesas en el final de la postconvertibilidad

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Estrategias económicas y desigualdad social. Dinámicas de consumo, ahorro y finanzas de familias cordobesas en el final de la postconvertibilidad; Economic strategies and social inequality. Dynamics of consumption, savings and finances of families in Córdoba at the end of post-convertibility Assusa, Gonzalo; Freyre, Maria Laura; Merino, Francisco El presente artículo tiene como objetivo el abordaje de las prácticas económicas deprovisión de recursos, consumo, ahorro y acceso a servicios financieros de familiascordobesas desde la perspectiva de la desigualdad de clase. Para ello, recuperaherramientas de la teoría de la práctica, los estudios de estratificación y los estudiossociales de la economía. Aplica una metodología mixta en torno a un procesamientoestadístico multidimensional y al análisis cualitativo de entrevistas en profundidad areferentes de familias de las distintas posiciones del espacio social de Córdoba.; This article addresses the economic practices of resources provision, consumption, savings and access to financial services of families in Córdoba, Argentina, from the perspective of class inequality. In order to do so, it makes use of tools from practice theory, stratification studies and economic ethnography. The approach of this research applies a mixed methodology based on a multidimensional statistical processing and qualitative analysis of in-depth interviews carried out with family-representatives from different social backgrounds.

Incipient Neighborhood and Socioeconomic Stratification Associated to Nutritional Status in Indigenous Qom Preschoolers from Formosa, Argentina

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Incipient Neighborhood and Socioeconomic Stratification Associated to Nutritional Status in Indigenous Qom Preschoolers from Formosa, Argentina Olmedo, Sofía; Valeggia, Claudia; Berra, Silvina del Valle Indigenous populations in Latin America are among the most socially vulnerable groups and their children often suffer severe deprivation in terms of access to proper nutrition, water, and shelter. This study describes the nutritional status of Qom preschoolers in general, and by neighborhood area and family’s socioeconomic characteristics in a peri-urban village of Formosa, Argentina. Across-sectional study was carried out between January and December 2016, with 160 Qom children between 2 and 5 years of age. Interviews and anthropometric measures were conducted at the children’s homes. Nutritional status was determined by body mass index. The prevalence of excess weight (overweight + obesity) and of stunting were associated with neighborhood area and socioeconomic level. The overall prevalence of stunting was 15.6% and it was found to be higher (25.8%) in areas of relatively lower access to material resources. The overall prevalence of excess weight reached 25%; however, neighborhood areas with greater access to material resources had a significantly higher prevalence of children with excess weight (41.2%). Despite the entire community living under the line of poverty, we found differences in nutritional status by neighborhood areas, suggesting an incipient social stratification and a deepening of inequalities in access to resources.

Wind-eroded nitrogen balance in an entic haplustoll under different tillage conditions

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Wind-eroded nitrogen balance in an entic haplustoll under different tillage conditions Abascal, Sergio Alberto; Buschiazzo, Daniel Eduardo; Asensio, Carlos Little information is available on the combined effect of weather conditions and tillage systems on nitrogen lost from wind erosion.A field study was carried out on an Entic Haplustoll to analyze N content in the eroded material. Field measurements were madeduring the winter fallow (WF) and summer fallow (SF) periods in conventional (CT) and a no-till (NT) fields. Winters are morehumid and less windy than summers. Results showed that there were N losses and gains by the wind with both tillage systems andin both seasons. Highest N gains in the crop cycle were 17.1 kg ha-1and maximum losses 7.5 kg ha-1. N gains were detected underhigh mass flow (the amount of wind-transported material entering the plots from external sources), vegetation cover and soil surfaceroughness conditions. When these variables were low, N was lost (or gains were low). Tillage system affected N transport morethan season, through its effect on the soil surface cover (mainly with NT) or soil surface roughness (mainly with CT). Only whenthe mean wind speed was 2.3 times higher than the threshold wind speed was the effect of tillage on N transport by wind negligibleunder both NT and CT.

First nearly complete skull of Gallotia auaritae (lower-middle Pleistocene, Squamata, Gallotiinae) and a morphological phylogenetic analysis of the genus Gallotia

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First nearly complete skull of Gallotia auaritae (lower-middle Pleistocene, Squamata, Gallotiinae) and a morphological phylogenetic analysis of the genus Gallotia Cruzado Caballero, Penélope; Castillo Ruiz, Carolina; Bolet, Arnau; Colmenero, Juan Ramón; De la Nuez, Julio; Casillas, Ramón; Llacer, Sergio; Bernardini, Federico; Fortuny, Josep The Canary Islands are an Atlantic archipelago known for its high number of endemic species. Among the most known endemic vertebrate species are the giant lizards of the genus Gallotia. We describe the cranial osteology of the first almost complete and articulated fossil skull of the taxon Gallotia auaritae, recovered from the lower-middle Pleistocene of the La Palma island. In this work, X-ray computed microtomography images were used to perform an exhaustive phylogenetic analysis where most of the extant and fossil species of the genus Gallotia were included for first time. This analysis recovered a monophyletic Gallotia clade with similar topology to that of molecular analyses. The newly described specimen shares some characters with the group formed by G. bravoana, G. intermedia and G. simonyi, G. auaritae, and its position is compatible with a referral to the latter. Our study adds new important data to the poorly known cranial morphology of G. auaritae, and the phylogenetic analysis reveals an unexpected power of resolution to obtain a morphology-based phylogeny for the genus Gallotia, for inferring the phylogenetic position of extinct species and for helping in the identification of fossil specimens.

Escenas de una vida bohemia en la noche setentista: Memorias de María Moreno

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Escenas de una vida bohemia en la noche setentista: Memorias de María Moreno Viu Adagio, Julieta El libro de memorias Black out (2016) de María Moreno recrea momentos particulares del campo cultural y artístico argentino que muestran otra cara de los años setenta: se trata de una bohemia que se involucra en una política de los textos antes que en una política en los textos. Con esa escritura propia de la autora, alejada de cualquier simplismo y no exenta de ironía, Moreno repasa noches compartidas con colegas de redacción, historias de excesos y alcohol, poniendo en juego preceptos familiares y morales. Desde una perspectiva biopolítica, en este artículo, señalamos la desnaturalización de ordenamientos y jerarquías establecidos al cuestionar de lleno mandatos sociales instituidos sobre los cuerpos individuales y colectivos.; Black out (2016) by María Moreno is a memoir that recreates particular moments of the Argentine cultural and artistic field that shows another face of the seventies: a bohemian that gets involved in a politics of the texts rather than a policy in the texts. With that writing away from any simplicity, not without irony, Moreno reviews shared nights with colleagues, stories of excess and alcohol, putting into play family and moral precepts. From a biopolitical perspective, in this article we point out the denaturalization of established orders and hierarchies by fully questioning the social mandates instituted on individual and collective bodies.

El mestizaje en América Latina durante la primera mitad del siglo XX

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El mestizaje en América Latina durante la primera mitad del siglo XX; A mestiçagem na América Latina na primeira metade do século XX Mailhe, Alejandra Marta ¿Por qué alquimia se mezclan las culturas? ¿Qué noción de sujeto subyace al mestizaje como proceso? ¿Es posible pensar el mestizaje por fuera de la dialéctica hegeliana? ¿Y qué connotaciones políticas anidan bajo cada modelo teórico? Me propongo indagar en torno a estas preguntas considerando algunos ensayos latinoamericanos de las primeras décadas del siglo XX, en los cuales el problema teórico del mestizaje resulta central para definir la identidad nacional y continental. Para ello, atenderé a algunos textos que elogian el mestizaje indohispánico en Argentina, México y Perú, de Ricardo Rojas, Manuel Gamio, José Vasconcelos y José Uriel García.; Por meio de que alquimia se misturam as culturas? Que noção de sujeito subjaz à mestiçagem como processo? É possível pensar a mestiçagem por fora da dialética hegeliana? E que conotações políticas aninham sob cada modelo teórico? Eu me proponho indagar em torno dessas perguntas considerando alguns ensaios latino-americanos das primeiras décadas do século XX, nos quais o problema teórico da mestiçagem resulta central para definir a identidade nacional e continental. Para isso, atenderei a alguns textos que elogiam a mestiçagem indohispânica em Argentina, México e Perú, de Ricardo Rojas, Manuel Gamio, José Vasconcelos e José Uriel García.

Translational research in pituitary tumours

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Translational research in pituitary tumours Stalla, Günter K; Dimopoulou, Christina; Jung Sievers, Caroline; Arzt, Eduardo Simon; Paez Pereda, Marcelo; Theodoropoulou, Marily; Ciato, Denis; Renner, Ulrich Although effective treatment regimens (surgical resection, drug treatment with dopamine agonists or somatostatin analogues, radiotherapy) have been established for the therapy of most pituitary tumours, a considerable proportion of affected patients cannot completely cured due to incomplete resection or drug resistance. Moreover, even if hormone levels have been normalized, patients with hormone-secreting tumours still show persistent pathophysiological alterations in metabolic, cardiovascular or neuropsychiatric parameters and have an impaired quality of life. In this review reasons for the discrepancy between biochemical cure and incomplete recovery from tumour-associated comorbidities are discussed and the clinical management is delineated exemplarily for patients with acromegaly and Cushing's disease. In view of the development of additional treatment concepts for the treatment of pituitary adenomas we speculate about the relevance of RSUME as a potential target for the development of an anti-angiogenic therapy. Moreover, the role of BMP-4 which stimulates prolactinoma development through the Smad signalling cascade is described and its role as putative drug target for the treatment of prolactinomas is discussed. Regarding the well-known resistance of a part of somatotropinomas to somatostatin analogue treatment, recently identified mechanisms responsible for the drug resistance are summarized and ways to overcome them in future treatment concepts are presented. Concerning novel therapeutic options for patients with Cushing's disease the impact of retinoic acid, which is currently tested in clinical studies, is shown, and the action and putative therapeutic impact of silibinin to resolve glucocorticoid resistance in these patients is critically discussed.

Hernán Ronsino, por una literatura humana. Notas sobre un escritor necesario

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Hernán Ronsino, por una literatura humana. Notas sobre un escritor necesario Linares, Maximiliano "Vuelvo a elegir un relato de Ronsino con la esperanza de aclarar algunos motivos, expresa Beatriz Sarlo en el comienzo del ensayo número 15, 'Crimen pasional'", de los 33 que componen Ficciones argentinas (Mardulce, 2012). La producción del narrador bonaerense Hernán Ronsino (Chivilcoy, 1975) restituye la incomodidad pertinente a un canon pedagógico que no acostumbra prestar atención sino a aquello que se emplaza de modo acompasado a sus dictados o a aquello otro que lo interpela desde la diferencia o disidencia explícita. Sarlo, un poco más adelante, explicita: "Ronsino se ubica de modo deliberado, estéticamente consciente, en línea de diálogo con Juan José Saer, con Haroldo Conti, escritores a los que no se les escatima el reconocimiento pero de quienes la mayor parte de la ´literatura [argentina] actual´ permanece alejada, como si fueran un continente exhausto y todas las riquezas estuvieran en los dominios cuyo primer mapa trazó Manuel Puig". Las novelas de Ronsino La descomposición (2007), Glaxo (2009) y Lumbre (2013) parecerían no cumplimentar ninguna de las tres coordenadas dispuestas por las acertadas prerrogativas de la marginalidad en el campo literario (Jitrik, 1970): 1. El estilo de Ronsino conoce por completo los principios estéticos del discurso canónico; 2. No registramos un gesto deliberado ni no deliberado antihegemónico, los principios productivos se adecúan sin problema al movimiento del mercado; y 3. No visualizamos tampoco un posicionamiento y su consecuente neutralización provocados por disputas o rencillas literarias. Sin embargo, Ronsino no goza de la aceptación o popularidad de otros narradores contemporáneos (Cucurto, Incardona, Cabezón Cámara, Almada, entre otros [la mención de estos autores simplemente para contrastar el desconocimiento de Ronsino no por el hecho de que las poéticas de cada uno sean plausibles de comparación]) y, para expresarlo posicionados desde el eje seleccionado: tensiona internamente movimientos de inclusión o exclusión, por ejemplo cuando incomoda a su manera a un canon pedagógico que no resuelve cómo incorporarlo, cómo enseñarlo. Estos aspectos centrales para la lectura de la trilogía pampeana de Ronsino y, además, la combinación que produce la aparición de su último libro Cameron (2018) -en primera instancia fuera de ese territorio ficcional pampeano- nos habilitan a pensar y escandir nuestras notas sobre Hernán Ronsino como un escritor necesario.

Near-Field Enhancement Contribution to the Photoactivity in Magnetite-Gold Hybrid Nanostructures

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Near-Field Enhancement Contribution to the Photoactivity in Magnetite-Gold Hybrid Nanostructures Guzman, Federico Valentin; Mercadal, Pablo Agustin; Coronado, Eduardo A.; Encina, Ezequiel Roberto Hybrid nanostructures composed of magnetic iron oxides and plasmonic metals can convert light energy into chemical energy, and they can be easily manipulated through magnetic fields. As a consequence of these multifunctional features, they can be employed as magnetically recyclable heterogeneous photocatalysts. Herein, we report a two-step method for the preparation of magnetite (Fe3O4)-gold (Au) hybrid nanostructures in aqueous media. The obtained material resembles a core-satellite morphology of 60 nm Fe3O4 nanoparticles surrounded by nearly 20 nm spherical Au nanoparticles attached to their surface. The synthesized hybrid material exhibits enhanced capabilities for methylene blue photodegradation compared with bare Fe3O4 nanoparticles. Detailed electrodynamics simulations were performed to achieve further insight into the improved photoactive properties of the Fe3O4-Au hybrid nanostructures. The theoretical results show that the excitation of localized surface plasmon resonances in the Au component leads to greater light absorption in the Fe3O4 component, which ultimately impacts the improved photocatalytic properties of the hybrid nanostructure. Overall, this work provides a complementary approach toward a complete understanding of the enhanced photoactive properties of hybrid nanostructures and highlights the importance of considering their actual morphology into simulations.

Salud del vellón: Avances en el conocimiento de la "Lana Sisal"

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Salud del vellón: Avances en el conocimiento de la "Lana Sisal" Abdala, Alejandra Mariana; Robles, Carlos Alejandro La Lana Sisal es una dermatitis infecciosa caracterizada por la presencia de manchones oscuros en el vellón, que afecta a ovinos Merino de la Patagonia y cuya etiología permanecía incierta hasta el momento. Dado que produce un deterioro del vellón, genera pérdidas económicas al momento de la venta de la lana.

Free Womb Law, Legal asynchronies and Migrations: suing for an enslaved woman´s child in nineteenth century Rio de la Plata

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Free Womb Law, Legal asynchronies and Migrations: suing for an enslaved woman´s child in nineteenth century Rio de la Plata Candioti, Magdalena This article analyzes in depth the history of Petrona, an enslaved woman sold in Santa Fe (Argentina), sent to Buenos Aires and later possibly to Montevideo (Uruguay). By reconstructing her case, the article demonstrates how the legal status of enslaved persons was affected by the redefinitions of jurisdictions and by the forced or voluntary crossings between political units. This study also shows the circulation and uses of the Free Womb law in Argentina and Uruguay and traces legal experts' debates over its meaning. At the same time, it reflects on the knowledge enslaved people had of those abolitionist norms and how they used them to resist forced relocations, attempt favorable migrations, or achieve full freedom. The article crosses analytical dimensions and historiographies-legal, social, and political- and articulates them by reflecting more broadly on these factors: the impact of the revolution of independence on enslaved persons' lives, the scarce circulation of abolitionist public discourse in Río de la Plata, the gendered bias of the process, and the central yet untold uses of antislavery rhetoric in the national narratives.

Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in Caenorhabditis and Vertebrates

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Origin and Evolution of Two Independently Duplicated Genes Encoding UDP- Glucose: Glycoprotein Glucosyltransferases in Caenorhabditis and Vertebrates Caraballo, Diego Alfredo; Buzzi, Lucila Inés; Acosta Montalvo, Ana Gabriela; Modenutti, Carlos Pablo; Castro, Olga Alejandra; Rossi, Maria Susana UDP- glucose: glycoprotein glucosyltransferase (UGGT) is a protein that operates as the gatekeeper for the endoplasmic reticulum (ER) quality control mechanism of glycoprotein folding. It is known that vertebrates and Caenorhabditis genomes harbor two uggt gene copies that exhibit differences in their properties.Bayesian phylogenetic inference based on 195 UGGT and UGGT-like protein sequences of an ample spectrum of eukaryotic species showed that uggt genes went through independent duplications in Caenorhabditis and vertebrates. In both lineages, the catalytic domain of the duplicated genes was subjected to a strong purifying selective pressure, while the recognition domain was subjected to episodic positive diversifying selection. Selective relaxation in the recognition domain was more pronounced in Caenorhabditis uggt-b than in vertebrates uggt-2. Structural bioinformatics analysis revealed that Caenorhabditis UGGT-b protein lacks essential sequences proposed to be involved in the recognition of unfolded proteins. When we assayed glucosyltrasferase activity of a chimeric protein composed by Caenorhabditis uggt-b recognition domain fused to S. pombe catalytic domain expressed in yeast, no activity was detected.The present results support the conservation of the UGGT activity in the catalytic domain and a putative divergent function of the recognition domain for the UGGT2 protein in vertebrates, which would have gone through a specialization process. In Caenorhabditis, uggt-b evolved under different constraints compared to uggt-a which, by means of a putative neofunctionalization process, resulted in a non-redundant paralog. The non-canonical function of uggt-b in the worm lineage highlights the need to take precautions before generalizing gene functions in model organisms.

Reconfiguración del oligopolio mundial y cambio tecnológico frente a la agricultura 4.0: implicancias para la trayectoria de la maquinaria agrícola en Argentina

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Reconfiguración del oligopolio mundial y cambio tecnológico frente a la agricultura 4.0: implicancias para la trayectoria de la maquinaria agrícola en Argentina; Reconfiguration of the world oligopoly and technological change vis-à-vis the agriculture 4.0: implications for the trajectory of agricultural machinery in Argentina Lavarello, Pablo Jose; Bil, Damián Andrés; Vidosa, Regina; Langard, Federico Este trabajo analiza la denominada agricultura 4.0 como el proceso actual de convergencia entre la industria de maquinaria agrícola y las nuevas tecnologías digitales, y plantea que este es expresión de la creciente rivalidad al interior de los oligopolios mundiales. En este marco, este trabajo discute cómo las relaciones estables entre los miembros del oligopolio son puestas en tensión en el plano de la competencia tecnológica por el control de las plataformas y los estándares en la transferencia de datos. Se analiza cómo la trayectoria histórica de esta industria en Argentina y su evolución reciente se ven afectadas por la difusión de la agricultura de precisión, planteando los desafíos que implica para esta industria.; This work analyzes the agriculture 4.0 as the contemporary convergence process between the agriculture machinery industry and the new digital technologies, which refletcts an increasing rivalry in global oligopolies. From this framework, it discusses how stable relationships among oligopoly members are jeopardized as soon as different oligopolies fight for the control of global platforms and data standards. This work analyzes how the historic trajectory of Argentine’s agriculture machinery has been affected by recent diffusion of precision agriculture, and the challenges for this industry.

Un análisis histórico y geográfico de la articulación de actores sociales en la apertura de escuelas de alternancia

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Un análisis histórico y geográfico de la articulación de actores sociales en la apertura de escuelas de alternancia; A historical and geographic analysis of the ways in which social actors articulate their practice in order to establish pedagogy of alternation schools Miano, María Amalia; Heras Monner Sans, Ana Ines Realizamos una reconstrucción histórica y geográfica del surgimiento y desarrollo de la pedagogía de la alternancia tal como se fue generando en diferentes continentes, centrándonos en las experiencias de Francia, Brasil y Canadá. Interpretamos la forma en que diversos actores sociales se han auto organizado en distintos países para abrir y sostener en el tiempo escuelas rurales de alternancia. Nos hemos preguntado: ¿en qué momentos y lugares se configuran procesos de auto organización comunitaria para abrir escuelas que permitan a los jóvenes de ámbitos rurales continuar con sus estudios luego de la educación primaria? ¿Qué actores sociales participan en cada caso y a qué tipos de demandas responden? Nuestros resultados muestran que la expansión de la pedagogía de la alternancia en el mundo se fue realizando a partir de contactos entre grupos que comparten una orientación similar en diferentes lugares geográficos (respeto por las formas culturales de la ruralidad, interés en construir instituciones educativas que permitan la participación de diferentes actores sociales, generación de herramientas pedagógicas distintivas). Así, esta pedagogía puede considerarse, tal como algunos de sus antecedentes lo indican, como un movimiento (inclusive de carácter internacional) conservando sin embargo el carácter singular de cada experiencia en cada historia y geografía particular.; We present an analysis of the pedagogy of alternation based on a historical and geographical reconstruction of its origins and development. We also specifically discuss how this type of schooling process took place in France, Brazil and Canada. We focus on the ways in which different social actors self-organized in order to create and sustain rural schools over time. Our guiding questions were: Where and when do community processes of self organization take place so that these kinds of schools are opened and students can continue their secondary education in rural areas? What are the specific social actors that participate and to what specific community needs do they respond? Our findings show that the pedagogy of alternation established itself worldwide in as much as a network of different social actors developed because they identified themselves with core orientation, regardless of their geographical location, as follows: respect for rural cultural ways of living; interest in creating schools that allow for diverse social actors’ participation; construction of specific pedagogical tools. Therefore, this pedagogy may be considered as a movement worldwide yet simultaneously situated in each specific social, historical and geographical context.

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