Knock-down of arabidopsis PLC5 reduces primary root growth and secondary root formation while overexpression improves drought tolerance and causes stunted root hair growth Zhang, Qianqian; Van Wijk, Ringo; Zarza, Xavier; Shahbaz, Muhammad; Van Hooren, Max; Guardia, Aisha Elena; Scuffi, Denise; Garcia-Mata, Carlos; Van Den Ende, Wim; Hoffmann-Benning, Susanne; Haring, Michel A.; Laxalt, Ana Maria; Munnik, Teun Phospholipase C (PLC) is a well-known signaling enzyme in metazoans that hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP 2) to produce inositol 1,4,5-trisphosphate and diacylglycerol as second messengers involved in mutiple processes. Plants contain PLC too, but relatively little is known about its function there. The model system Arabidopsis thaliana contains nine PLC genes. Reversed genetics have implicated several roles for PLCs in plant development and stress signaling. Here, PLC5 is functionally addressed. Promoter-β-glucuronidase (GUS) analyses revealed expression in roots, leaves and flowers, predominantly in vascular tissue, most probably phloem companion cells, but also in guard cells, trichomes and root apical meristem. Only one plc5-1 knock-down mutant was obtained, which developed normally but grew more slowly and exhibited reduced primary root growth and decreased lateral root numbers. These phenotypes could be complemented by expressing the wild-type gene behind its own promoter. Overexpression of PLC5 (PLC5-OE) using the UBQ10 promoter resulted in reduced primary and secondary root growth, stunted root hairs, decreased stomatal aperture and improved drought tolerance. PLC5-OE lines exhibited strongly reduced phosphatidylinositol 4-monophosphate (PIP) and PIP 2 levels and increased amounts of phosphatidic acid, indicating enhanced PLC activity in vivo. Reduced PIP 2 levels and stunted root hair growth of PLC5-OE seedlings could be recovered by inducible overexpression of a root hair-specific PIP 5-kinase, PIP5K3. Our results show that PLC5 is involved in primary and secondary root growth and that its overexpression improves drought tolerance. Independently, we provide new evidence that PIP 2 is essential for the polar tip growth of root hairs.

FITNESS, a CCT domain-containing protein, deregulates reactive oxygen species levels and leads to fine-tuning trade-offs between reproductive success and defence responses in Arabidopsis Osella, Ana Virginia; Mengarelli, Diego Alberto; Mateos, Julieta Lisa; Dong, Shuchao; Yanovsky, Marcelo Javier; Balazadeh, Salma; Valle, Estela Marta; Zanor, María Inés Environmental stresses are the major factors that limit productivity in plants. Here, we report on the function of an uncharacterized gene At1g07050, encoding a CCT domain-containing protein, from Arabidopsis thaliana. At1g07050 expression is highly repressed by oxidative stress. We used metabolomics, biochemical, and genomic approaches to analyse performance of transgenic lines with altered expression of At1g07050 under normal and oxidative stress conditions. At1g07050 overexpressing lines showed increased levels of reactive oxygen species (ROS), whereas knock-out mutants exhibited decreased levels of ROS and higher tolerance to oxidative stress generated in the chloroplast. Our results uncover a role for At1g07050 in cellular redox homeostasis controlling H2O2 levels, due to changes in enzymes, metabolites, and transcripts related to ROS detoxification. Therefore, we call this gene FITNESS. Additionally, several genes such as ACD6, PCC1, and ICS1 related to salicylic acid signalling and defence were found differentially expressed among the lines. Notably, FITNESS absence significantly improved seed yield suggesting an effective fine-tuning trade-off between reproductive success and defence responses.

Cooperativas de trabajo federadas de Entre Ríos: desafíos e implicancias Escalada, Nahuel Dario Este trabajo toma como objeto de estudio a la Federación de Cooperativas de Trabajo de la Provincia de Entre Ríos, cooperativa de segundo nivel que reúne a catorce cooperativas de trabajo de la construcción, una cooperativa textil, una radial y una educacional. En virtud de generar un marco conceptual se realiza aquí un análisis de los términos que refieren a las cooperativas de trabajo, su doctrina, principios fundamentales y modo de organización. Se procede también a caracterizar los rasgos particulares que las diferencian de otras cooperativas. Posteriormente se toma en consideración a las Cooperativas de Trabajo Federadas de Entre Ríos Ltda. (de aquí en más CO.TRA.FER.) a modo de entender su constitución, los procesos que se han generado en su interior y el funcionamiento de las cooperativas que la componen, focalizando principalmente en las de mayor actividad, que son las dedicadas a la construcción. Para ello se realizaron entrevistas semiestructuradas al consejo directivo de la COTRAFER como así también a representantes de las cooperativas que la integran. Se tomaron también en cuenta las opiniones de socios, sin embargo solo se pudo establecer contacto con aquellos que frecuentan las reuniones generales de la federación. Por otro lado se entrevistó al presidente del instituto provincial de cooperativismo y mutualismo de la provincia de Entre Ríos y al secretario de Economía Social de la ciudad de Gualeguaychu a fin de poder percibir la visión del Estado en cuanto al funcionamiento de las cooperativas. En última instancia el trabajo aborda dos aspectos básicos que se desprenden del estudio de la Federación: la conceptualización que se ha generado respecto del mundo del trabajo en relación al cooperativismo; y por otro lado la circulación y la configuración del poder que se da dentro de las cooperativas que la conforman. Este estudio da lugar a la reflexión final y a la caracterización de la situación de la Federación como tal.

Endothelial Lipase Is an Alternative Pathway for Fatty Acid Release from Lipoproteins: Evidence from a High Fat Diet Model of Obesity in Rats Barchuk, Magalí; Miksztowicz, Verónica Julieta; Zago, Valeria; Cevey, Ágata Carolina; López, Graciela; Goren, Nora Beatriz; Friedman, Silvia; Gelpi, Ricardo Jorge; Morales, Maria Celina; Fernandez Tomé, María del Carmen; Schreier, Laura Ester; Berg, Gabriela Alicia Lipoprotein lipase (LPL) and endothelial lipase (EL) are involved in lipoprotein metabolism. In insulin-resistance, their behavior is altered. Peroxisome proliferator-activated receptors (PPAR) and apoproteins (apo)CII and CIII could be partly responsible for these alterations. To evaluate this response, we assessed Lpl and Lipg expression, protein levels, and enzyme activity in adipose tissue (AT) and heart in an obesity model. Besides, we assessed the role of PPAR and apoC. Male Wistar rats were fed with standard diet (Control, n = 14) or high-fat diet (HFD, n = 14) for 14 weeks. Glucose and lipoprotein profiles were measured. Histological studies were performed in heart and epididymal AT. Lpl and Lipg were assessed by reverse transcription polymerase chain reaction (RT-qPCR), protein levels by Western Blot, and activities by radiometric assays. Cardiac and AT PPAR expression were measured by Western Blot and hepatic Apoc2 and Apoc3 mRNA by RT-qPCR. In HFD, fat deposits were observed in hearts, whereas AT presented a higher adipocyte size. In heart and AT, no differences were found in Lipg mRNA between groups, while AT Lpl mRNA and LPL protein were decreased in HFD, without differences in heart. In both tissues, EL protein levels and activity were increased and inversely associated with decreased LPL activity, being partially responsible for the atherogenic lipoprotein profile in HFD. PPARγ expression in AT was decreased in HFD, without differences in cardiac PPARδ expression and hepatic apoC mRNA. The increase in EL activity could be an alternative pathway for fatty acid release from lipoproteins and uptake in tissues with decreased LPL activity. In AT, PPARγ could be involved in enzyme regulation.

Development of sigmoidal en-échelon microfractures in beryl and the role of strain localization evidenced by fluid inclusions Sosa, Graciela M.; Oriolo, Sebastián; van den Kerkhof, Alfons A combined fluid inclusion and microstructural study was carried out in beryl crystals from the San Cayetano Nb-Ta-bearing pegmatite (San Luis, Argentina). Primary aqueous-carbonic fluids (T0) were subsequently re-trapped during shearing, resulting in en-échelon microfractures. The more brittle behaviour of beryl compared to quartz makes this mineral more suitable for the preservation of fluid inclusions and microstructures. The primary inclusions T0 are preserved in strain-free domains, whereas the pseudo-secondary T1-to T3-type inclusions occur in domains showing intracrystalline deformation. CO2 was relatively immobile or reacted to form carbonate in early T1-type inclusions, whereas H2O preferentially migrated along microfractures and was trapped as T2-and T3-type inclusions. Short intragranular trails of fluid inclusions, representing en-échelon healed microfractures, resulted from progressive strain localization. Contrary to previous proposals, this new model implies the progressive thickness reduction of intracrystalline micro-shear zones. Besides, hydrolytic weakening linked to dislocation glide is the most likely mechanism to explain the evolution of fluid inclusions, with intracrystalline deformation enhancing anisotropic diffusion. This study highlights the potential of combined fluid inclusion and microstructural studies in order to understand the interaction between fluid activity and deformation. In this way, valuable insights can be provided into the progressive development of overprinted fabrics and low-to medium-temperature deformation mechanisms of minerals.

Modeling second-order data for classification issues: Data characteristics, algorithms, processing procedures and applications Azcarate, Silvana Mariela; de Araújo Gomes, Adriano; Muñoz de la Peña, Arsenio; Goicoechea, Hector Casimiro This review outlines some of the challenging aspects of applying second-order data modeling in classification issues analyzing selected examples of current applications. The main analytical platforms used for classification are briefly discussed from the application point of view, and the utilization of the generated data is illustrated. After a critical discussion of the advantages concerning the general features of the available algorithms and their underlying models, one example is presented and discussed in detail with the purpose of illustrating the high potentiality of second-order data modeling in the classification field. In addition, advanced data pre-processing tools, prior to multivariate analysis, are explained, and relevant tools are displayed. Finally, novelty prospects in multi-way classification area are presented.

Detección y caracterización de Escherichia coli productor de toxina Shiga en niños atendidos en un hospital pediátrico interzonal de la ciudad de La Plata; Detection and characterization of Shiga toxin-producing Escherichia coli in children treated at an inter-zonal pediatric hospital in the city of La Plata Oderiz, Sebastián; Leotta, Gerardo Anibal; Galli, Lucía Escherichia coli productor de toxina Shiga (STEC) es un patógeno transmitido poralimentos que puede causar diarrea acuosa, diarrea sanguinolenta (DS) y síndrome urémico hemolítico (SUH). El objetivo de este estudio fue determinar las características fenotípicas y genotípicas de cepas STEC aisladas de ni?nos con DS y SUH atendidos en un hospital pediátrico de la ciudad de La Plata en el período 2006-2012 y establecer la relación clonal de los aislamientos O157:H7 mediante electroforesis de campo pulsado. El porcentaje de muestras positivasfue de 4,9 y 39,2% en los pacientes que presentaron DS y SUH, respectivamente. Se aislaron 77 cepas STEC de 10 serotipos distintos, con el 100% de recuperación de colonias. El serotipo más frecuente fue O157:H7 (71,4%), seguido por O145:NM (15,6%). El 98,2% de los aislamientos O157:H7 correspondió al biotipo C y fue sensible a los antibióticos ensayados. Todos esos aislamientos presentaron el genotipo stx2, eae, fliCH7, ehxA, iha, efa, toxB, lpfA1-3 y lpfA2-2. Al estudiar la relación clonal de las cepas O157:H7, se identificaron un total de 42 patronescon al menos un 88% de similitud y se establecieron 6 clústeres que agruparon cepas con perfiles idénticos. Los aislamientos eae negativos pertenecieron a los serotipos O59:H19, O102:H6, O174:NM y O174:H21. Las cepas O59:H19 y O174:H21 fueron positivas para el gen aggR. Este estudio muestra que en la ciudad de La Plata y alrededores circulan STEC de diferentes serotipos y genotipos. A pesar de la diversidad genética observada entre los aislamientos O157:H7, algunos fueron indistinguibles por las técnicas de subtipificación utilizadas.; Shiga toxin-producing Escherichia coli (STEC) is a foodborne pathogen that can cause watery diarrhea, bloody diarrhea (BD), and hemolytic uremic syndrome (HUS). The objective of this study was to determine the phenotypic and genotypic profiles of STEC strains isolated from children with BD and HUS treated at a pediatric hospital in the city of La Plata in the period 2006-2012, and to establish the clonal relationship of O157:H7 isolates by pulsed field electrophoresis. The percentage of positive samples was 4.9% and 39.2% in patients with BD and HUS, respectively. Seventy-seven STEC strains from 10 different serotypes were isolated, with 100% colony recovery, O157:H7 being the most frequent (71.4%) serotype, followed by O145:NM (15.6%). An average of 98.2% of O157:H7 isolates belonged to biotype C and were sensitive to all the antibiotics tested. All of them (100%) carried genotype stx2, eae, fliCH7, ehxA, iha, efa, toxB, lpfA1-3 and lpfA2-2. When the clonal relationship of the O157:H7 strains was studied, a total of 42 patterns with at least 88% similarity were identified, and 6 clusters with identical profiles were established. The eae-negative isolates belonged to serotypes O59:H19, O102:H6, O174:NM and O174:H21. The strains O59:H19 and O174:H21 were positive for the aggR gene. This study shows that STEC of different serotypes and genotypes circulate in the city of La Plata and surroundings. Despite the genetic diversity observed between the O157:H7 isolates, some were indistinguishable by the subtyping techniques used.

Salinity is a prevailing factor for amelioration of wheat blast by biocontrol agents Cabot, Catalina; Bosch, Rafael; Martos, Soledad; Poschenrieder, Charlotte; Perello, Analia Edith Plants exposed to combined abiotic and biotic stress conditions may show enhanced pathogen resistance. Biocontrol agents (BCAs) can further contribute to ameliorate plant responses to these complex situations. In recent years, wheat production has been challenged by the expansion of salt-affected soils as well as by severe outbreaks of emerging diseases such as wheat blast. Here, the role of two BCAs, Pseudomonas stutzeri AN10 and Trichoderma harzianum Th56, was examined in salt-stressed seedlings infected with two Pyricularia oryzae isolates of contrasting aggressiveness. BCAs did not enhance plant tolerance to high salt stress. However, BCAs improved performance of salt-stressed wheat plants infected with the less aggressive Pyricularia isolate. The lower infection in salt-stressed BCAs-treated plants could be due to a salt-induced priming state required to trigger an early expression of plant defence genes.

The SOPHIE search for northern extrasolar planets: XIII. Two planets around M-dwarfs Gl617A and Gl96 Hobson, M. J.; Diaz, Rodrigo Fernando; Delfosse, X.; Astudillo-Defru, N.; Boisse, I.; Bouchy, F.; Bonfils, X.; Forveille, T.; Haran, Nora Selma; Arnold, L.; Borgniet, S.; Bourrier, V.; Brugger, B.; Cabrera, N.; Courcol, B.; Dalal, S.; Deleuil, M.; Demangeon, O.; Dumusque, X.; Ehrenreich, D.; Hébrard, G.; Kiefer, F.; Lopez, T.; Mignon, L.; Montagnier, G.; Mousis, O.; Moutou, C.; Pepe, F.; Rey, J.; Santerne, A.; Santos, N.; Stalport, M.; Ségransan, D.; Udry, S.; Wilson, P.A. We report the detection of two exoplanets and a further tentative candidate around the M-dwarf stars Gl96 and Gl617A, based on radial velocity measurements obtained with the SOPHIE spectrograph at the Observatoire de Haute-Provence. Both stars were observed in the context of the SOPHIE exoplanet consortium's dedicated M-dwarf subprogramme, which aims to detect exoplanets around nearby M-dwarf stars through a systematic survey. For Gl96 we present the discovery of a new exoplanet at 73.9 d with a minimum mass of 19.66 earth masses. Gl96 b has an eccentricity of 0.44, placing it among the most eccentric planets orbiting M stars. For Gl617A we independently confirm a recently reported exoplanet at 86.7 d with a minimum mass of 31.29 earth masses. Both Gl96 b and Gl617A b are potentially within the habitable zone, although the high eccentricity of Gl96 b may take it too close to the star at periapsis.

Antimicrobial resistance of thermotolerant campylobacter species isolated from humans, food-producing animals, and products of animal origin: A worldwide meta-analysis Rossler, Eugenia; Signorini Porchietto, Marcelo Lisandr; Romero Scharpen, Analía; Soto, Lorena Paola; Berisvil, Ayelén Patricia; Zimmermann, Jorge Alberto; Fusari, Marcia Lucia; Olivero, Carolina Raquel; Zbrun, María Virginia; Frizzo, Laureano Sebastian The objective of this meta-analysis was to summarize available information on the prevalence of antimicrobial-resistant Campylobacter species in humans, food-producing animals, and products of animal origin. A number of multilevel random-effect meta-analysis models were fitted to estimate mean occurrence rate of antimicrobial-resistant thermotolerant Campylobacter and to compare them throughout the years and among the species, food-producing animals (i.e., bovine, pigs, broilers, hen, goat, and sheep), country of origin, sample type, methodology to determine the antimicrobial susceptibility, and the species of Campylobacter. Among the considered antibiotics, thermotolerant Campylobacter showed the highest resistance to tetracycline (pool estimate [PE] = 0.493; 95% CI 0.466-0.519), nalidixic acid (PE = 0.385; 95% CI 0.348-0.423), and ciprofloxacin (PE = 0.376; 95% CI 0.339-0.415). In general, the prevalence of antimicrobial-resistant Campylobacter spp. was higher in hen, broilers, and swine. Campylobacter coli showed a higher prevalence of antimicrobial resistance than Campylobacter jejuni. Independent of the antimicrobial evaluated, the disk diffusion method showed higher prevalence of antimicrobial-resistant Campylobacter than the methods based on the minimum inhibitory concentration estimation. The meta-analysis showed that the prevalence of antimicrobial-resistant Campylobacter is relevant essentially in foods derived from hens and broilers, and it was observed worldwide. The prevalence of this pathogen is of public health importance and the increase in the prevalence of Campylobacter strains resistant to the antimicrobial of choice worsens the situation, hence, national authorities must monitor the situation in each country with the aim to establish the appropriate risk management measures.

Compensated convexity methods for approximations and interpolations of sampled functions in euclidean spaces: Applications to contour lines, sparse data, and inpainting Zhang, Kewei; Crooks, Elaine; Orlando, Antonio This paper is concerned with applications of the theory of approximation and interpolation based on compensated convex transforms developed in [K. Zhang, E. Crooks, and A. Orlando, SIAM J. Math. Anal., 48 (2016), pp. 4126--4154]. We apply our methods to (i) surface reconstruction starting from the knowledge of finitely many level sets (or ``contour lines""); (ii) scattered data approximation; (iii) image inpainting. For (i) and (ii) our methods give interpolations. For the case of finite sets (scattered data), in particular, our approximations provide a natural triangulation and piecewise affine interpolation. Prototype examples of explicitly calculated approximations and inpainting results are presented for both finite and compact sets. We also show numerical experiments for applications of our methods to high density salt & pepper noise reduction in image processing, for image inpainting, and for approximation and interpolations of continuous functions sampled on finitely many level sets and on scattered points.

La enseñanza de historia social en la carrera de enfermería; The teaching of social history in the nursing profession; A instrução da história social na carreira de enfermagem Cerdá, Juan Manuel; Ramacciotti, Karina Este artículo presenta una experiencia didáctica de Historia Social en el ámbito de la Licenciatura en Enfermería. En particular, se pretende mostrar cómo los documentales cinematográficos son un medio idóneo para la formación de recursos humanos en el ámbito específico de las ciencias sociales en general y de la enfermería en particular. El cine documental nos permite observar las expectativas y los imaginarios de ciertos grupos sociales, y permitir escuchar y ver a los participantes directos. Dicho aporte, luego, es puesto en tensión con las lecturas de clase y las vivencias de los propios estudiantes.; This study presents a teaching experience of Social History in Nursing undergraduate courses. Specifically, it has the aim to show how cinematographic documentaries are a suitable tool to train human resources in the Social Sciences field and notably in Nursing. Documentaries allow nursing professionals to observe expectations and the collective imaginary of specific social groups, allowing to see and listen to direct participants. This contribution is used together with readings during classes and students experiences.; Este trabalho apresenta uma experiência didática de História Social no curso de Enfermagem. Em particular, pretende-se mostrar como os documentários cinematográficos são um meio idôneo para a formação de recursos humanos no âmbito das Ciências Sociais em geral e da Enfermagem em particular. O documentário nos permite observar as expectativas e os imaginários de determinados grupos sociais e ouvir/ver os participantes diretos. Tal contribuição é colocada em diálogo com as leituras em sala de aula e vivências dos próprios estudantes.

Influence of exchange in NMR pore size/relaxation correlation experiments Silletta, Emilia Victoria; Franzoni, Maria Belen; Monti, Gustavo Alberto; Acosta, Rodolfo Héctor The influence of molecular exchange in porous polymeric systems on experiments that simultaneously correlate and determine pore length scales and surface relaxivities is studied. Pore length scales are determined by taking advantage of the internal field gradients generated by the difference in magnetic susceptibility between the polymer matrix and the contained water, namely the Decay Due to the Internal Field experiment. Transverse relaxation is codified in the detection period thus enabling correlation with the pore length. For the hierarchical very well connected porous polymer system, the considerable molecular exchange of water between different environments renders signals in the two-dimensional maps that make the determination of the surface relaxivity a complex problem.

Haloarchaea from the Andean Puna: Biological Role in the Energy Metabolism of Arsenic Ordoñez, Omar Federico; Rasuk, Maria Cecilia; Soria, Mariana Noelia; Contreras, Manuel; Farias, Maria Eugenia Biofilms, microbial mats, and microbialites dwell under highly limiting conditions (high salinity, extreme aridity, pH, and elevated arsenic concentration) in the Andean Puna. Only recent pioneering studies have described the microbial diversity of different Altiplano lakes and revealed their unexpectedly diverse microbial communities. Arsenic metabolism is proposed to be an ancient mechanism to obtain energy by microorganisms. Members of Bacteria and Archaea are able to exploit arsenic as a bioenergetic substrate in either anaerobic arsenate respiration or chemolithotrophic growth on arsenite. Only six aioAB sequences coding for arsenite oxidase and three arrA sequences coding for arsenate reductase from haloarchaea were previously deposited in the NCBI database. However, no experimental data on their expression and function has been reported. Recently, our working group revealed the prevalence of haloarchaea in a red biofilm from Diamante Lake and microbial mat from Tebenquiche Lake using a metagenomics approach. Also, a surprisingly high abundance of genes used for anaerobic arsenate respiration (arr) and arsenite oxidation (aio) was detected in the Diamante’s metagenome. In order to study in depth the role of arsenic in these haloarchaeal communities, in this work, we obtained 18 haloarchaea belonging to the Halorubrum genus, tolerant to arsenic. Furthermore, the identification and expression analysis of genes involved in obtaining energy from arsenic compounds (aio and arr) showed that aio and arr partial genes were detected in 11 isolates, and their expression was verified in two selected strains. Better growth of two isolates was obtained in presence of arsenic compared to control. Moreover, one of the isolates was able to oxidize As[III]. The confirmation of the oxidation of arsenic and the transcriptional expression of these genes by RT-PCR strongly support the hypothesis that the arsenic can be used in bioenergetics processes by the microorganisms flourishing in these environments.

Spectral characteristics of road surfaces and eye transmittance: Effects on energy efficiency of road lighting at mesopic levels Preciado Olvera, Oscar Ulises; Manzano, Eduardo Roberto In 2010, the CIE published a recommended system for mesopic photometry based on visual performance. According to this system, scenes illuminated at mesopic levels with light sources of high S/P ratio, will produce better visual performance than those illuminated with light sources of a lower S/P ratio at equal photopic luminance. However, there could be other factors affected by SPD that, when quantified, could lead to a contradictory final effect. The scope of this paper was to evaluate how road lighting is affected by the spectral road surface reflectance and by the human eye transmittance as people get older. Our results suggest that the benefits of considering the mesopic vision effect for light sources with high S/P ratios are totally counteracted by the other two effects at mesopic luminances between 0.75 cd/m2 and 1.73 cd/m2 for people between 20 and 60 years of age, depending on the light source and the age of observers.

Acoustic confinement phenomena in oxide multifunctional nanophononic devices Bruchhausen, Axel Emerico; Lanzillotti Kimura, Norberto Daniel; Jusserand, B.; Soukiassian, A.; Schlom, D. G.; Dekorsy, T.; Fainstein, Alejandro The engineering of phononic resonances in ferroelectric structures appears as a new knob in the designand realization of novel multifunctional devices. In this work we experimentally study phononicresonators based on insulating (BaTiO 3 , SrTiO 3 ) and metallic (SrRuO 3 ) oxides. We experimentallydemonstrate the confinement of acoustic waves in the 100 GHz frequency range in a phonon nanocavity,the time and spatial beatings resulting from the coupling of two different hybrid nanocavities forming anacoustic molecule, and the direct measurement of Bloch-like oscillations of acoustic phonons in a systemformed by 10 coupled resonators. By means of coherent phonon generation techniques we study thephonon dynamics directly in the time-domain. The metallic SrRuO 3 introduces a local phonon generatorand transducer that allows for the spatial, spectral and time-domain monitoring of the complex generatedwaves. Our results introduce ferroelectric cavity systems as a new tool for the study of complex wavelocalization phenomena at the nanoscale.

Ricardo Piglia, editor Esposito, Fabio El trabajo se propone reconstruir la trayectoria de Ricardo Piglia como editor, desde sus primeras colaboraciones para la efímera editorial Nueve 64 en los primeros años de la década de 1960 hasta la dirección de la colección Serie del Recienvenido para el Fondo de Cultura Económica durante los últimos años de su vida, pasando por sus trabajos como editor freelance en Jorge Álvarez y Tiempo Contemporáneo. Su trabajo de editor fue algo más que un medio de vida cuando aún no podía mantenerse con la venta de sus libros. Fue una actividad que le permitió introducirse en el mundo literario y construir una carrera de escritor al amparo de un nuevo público lector que consumía con avidez los libros e impresos ofrecidos por las editoriales vinculadas con la nueva izquierda.; This essay aims to reconstruct the trajectory of Ricardo Piglia as editor, from his first collaboration for the ephemeral editorial Nueve 64 in the early 1960s to the collection Serie del Recienvenido for Fondo de Cultura Económica, in the later years of his life, and his work as freelance editor in Jorge Álvarez and Tiempo Contemporáneo. His work as editor was more than a means of subsistence when he still could not support himself with book sales. It was an activity that allowed him to introduce himself in the literary world and build a writing career under the wing of a new reading public that readily consumed the books and printed materiales offered by editorials related to the New Left.

Modalidades de explotación, procesamiento y consumo de pinnípedos en la margen meridional de Tierra del Fuego Martinoli, Maria Paz En términos generales, en cuanto al modo de subsistencia, es posible sostener que los pinnípedos fueron una de las fuentes energéticas principales de los grupos que habitaron el sur del archipiélago fueguino. No obstante, se observa variabilidad temporo-espacial en la importancia económica de estas presas en la dieta de los cazadores-recolectores-pescadores de esta amplia región. En algunos trabajos se avanzó sobre aspectos relacionados con la explotación de estos animales, particularmente en la región central de la costa norte canal Beagle: dos contextos del Holoceno medio, el Segundo Componente de Túnel I (Schiavini 1990, 1993) y el Segundo Componente de Imiwaia I. Sin embargo, en la mayoría de los conjuntos de la costa sur del archipiélago fueguino -especialmente en Moat, Península Mitre y en la Isla delos Estados- se desconocen las posibles pautas de aprovisionamiento, procesamiento, transporte y consumo seleccionadas por los grupos humanos que habitaron la región, y si estas variaron a lo largo del tiempo. El objetivo principal de la presente tesis es analizar en perspectiva comparativa las modalidades de explotación de pinnípedos en la costa sur de Tierra del Fuego y en la Isla de los Estados, y sus variaciones a lo largo del Holoceno.

Un grupo de científicos locales creó un kit innovador para detectar infecciones en personas y animales.

Evaluation of classical reinforcement and passive control systems on a reinforced concrete bridge subjected to seismic loading Nanclares, Germán Aníbal; Ambrosini, Ricardo Daniel; Curadelli, Raul Oscar In this paper, different strategies are studied with the main objectiveto reduce structural demand and damage of an existent bridge in Mendoza,Argentina, with post-tensioning reinforced concrete girders that are a commonstructural typology in the region. A numerical study was carried out with thispurpose. The numerical model was calibrated against experimentalmeasurements of vibration natural frequencies. The alternatives studied are:a) classical reinforcement of the structural overall stiffness; b) tuned massdampers; c) viscous dampers; d) metallic dampers. The model is subjected toreal near-fault seismic records, thereby obtaining response parameters toevaluate the efficiency of each protective system. The response is evaluated notonly in terms of reduction of displacements, but also in increasing of shearforce in key elements, which is a negative characteristic of some of the systemsstudied. Advantages and disadvantages of each studied system are highlighted.