Determination of crystallographic texture in polycrystalline materials from wavelength-resolved neutron transmission experiments: application to high-symmetry crystals Vicente Alvarez, Miguel Angel; Malamud, Florencia; Santisteban, Javier Roberto Wavelength-resolved neutron transmission experiments are useful for characterizing the microstructure of macroscopic specimens with 2D spatial resolution perpendicular to the beam direction. The crystallographic texture can affect the neutron transmission in the thermal neutron energy range, which manifests as changes in the shape and height of Bragg edges as a function of neutron wavelength. Models have been proposed to predict the transmission of textured polycrystalline materials from knowledge of the material texture and have proved to accurately predict the observed transmission data. In recent work, a novel method was described and tested for obtaining texture integral parameters from the combined analysis of transmission data measured along several directions of a specimen in a hexagonal crystal Zr alloy. However, this procedure has limitations when dealing with high-symmetry crystal structures. In this work, a generalization of such a method based on the expansion of the orientation distribution function (ODF) in symmetric generalized spherical harmonics that is applicable to all crystal and sample symmetries is presented. Using this method, the low-order Fourier coefficients of the ODF can be estimated by analyzing transmission data obtained for a reduced set of beam directions. This method was verified using a cubic Cu sample, for which transmission data were available along five different directions. Two sample symmetries were assumed to reduce the number of Fourier coefficients of the ODF. In the case of cylindrical symmetry (fiber-type texture), the results were good; but in the case of orthorhombic symmetry, some bias was observed which was attributed to the reduced number of beam directions used to perform the evaluation.

Efecto de la intensidad de las lluvias sobre la acumulación de resina de Grindelia chiloensis en el suelo: implicancias para la restauración ecológica Rajnoch, María Gimena; Pérez, D. R.; Ravetta, Damián Andrés En ambientes áridos, debido a las presiones ambientales, las plantas han desarrollado una gran diversidad de metabolitos secundarios carbonados como las resinas, los politerpenos, las ceras, las gomas, entre otros. En particular, para las resinas se han encontrado varias funciones y se ha evidenciado la formación de costras fitoquímicas en el suelo por su acumulación bajo el canopeo de plantas como Grindelia chiloensis (Asteraceae) y Larrea divaricata (Zygophilaceae). Estas resinas modifican las propiedades físicas del suelo y la dinámica del agua en el suelo. En este trabajo caracterizamos el transporte de ácidos diterpénicos de G. chiloensis, generado por las lluvias, hacia la superficie del suelo y su acumulación. A partir de plántulas fue posible promover la formación de costras fitoquímicas en un período de dos años, en un experimento en el que se simularon precipitaciones de diferentes intensidades. Nuestros resultados también muestran que la intensidad de las precipitaciones determina la cantidad de resina removida y el contenido de resina del suelo. Debido a su efecto en las propiedades físicas del suelo y en la dinámica del agua, se propone que las costras fitoquímicas podrían modular procesos biológicos del suelo y tener una aplicación potencial para reiniciar la sucesión ecológica de sitios degradados o desertificados, al igual que las costras biológicas. En este contexto, los resultados obtenidos nos permiten pensar en diseños para la restauración que promuevan, imiten o aceleren el proceso natural de formación de costras.

El Genocidio como un dispositivo del olvido, la literatura como un dispositivo de la memoria: la Shoá y la Dictadura en la literatura argentina; Genocide as a tool to forget, literature as a tool to remember: the Shoah and the Dictatorship in Argentine literature Niemetz, Diego En la órbita de la postmemoria, heredar la experiencia de los mayores es un tópico revisitado una y otra vez por los escritores argentinos contemporáneos. Este trabajo se centra en el análisis de cuatro obras de la literatura argentina reciente que recuperan los relatos de los antepasados en forma de memoria familiar, pero que además proponen una reflexión acerca de la transmisibilidad de esas memorias y de la carga que supone. A partir de la superposición de experiencias familiares durante diferentes procesos genocidas, los textos postulan un borramiento de fronteras geográficas y temporales, que repercute en la presentación de los hechos y que, a partir de ese mecanismo, perduran en un presente sin solución de continuidad con el pasado ni con el futuro. Entre la persistencia y la superposición de las memorias genocidas y el trauma entendido como herencia, las producciones analizadas parecen perseguir un fin emancipatorio, de acuerdo a una de las famosas tesis sobre la historia de Walter Benjamin.; In the orbit of postmemory, inheriting the experience of the elders is a topic revisited over and over by contemporary Argentine writers. This article focuses on the analysis of four works of recent Argentine literature that recover the stories of ancestors in the form of family memories, but also propose a reflection on the transmissibility of these memories and the burden that they place on a person. Based on the overlapping of family experiences during different genocidal processes, the texts postulate an erasure of geographical and temporal borders, which affects the presentation of the facts and which, based on this mechanism, persist in a present that melts with the past or the future. Between the persistence and overlapping of genocidal memories and trauma understood as inheritance, the analyzed productions seem to pursue an emancipatory goal, according to one of Walter Benjamin’s famous theses on history.

Entre la opacidad y la transparencia: Cine, transición y monstruos; Between opacity and transparency: Cinema, transition and monsters Montes, Viviana Andrea Los estudios sobre el cine argentino de la primera década posdictadura se han planteado con frecuencia en términos de polarización: opacidad o transparencia, continuidad o ruptura con el cine previo. Otra clave de lectura interesante para abordar la producción audiovisual del decenio puede ser su eminente carácter transicional. El cine de esos años, por un lado, fue testigo y artífice de la transición política entre terrorismo de Estado y democracia; por otro, se vio conmovido por la transición tecnológica que impuso el avance del video como nuevo modo de producción y de circulación de imágenes. Al mismo tiempo vivenció su propia transición, que denominaremos transición cinematográfica.La transición se presenta como intersticio entre lo viejo y lo nuevo que se entrelazan creando formas que comparten características del tiempo pretérito y del porvenir sin identificarse completamente con ninguno de ellos. La coexistencia –no sin disputa- de narrativas y modos de representación es un rasgo tan frecuente como distintivo. Este trabajo busca indagar en los monstruos que habitan el claroscuro de ese cine constituyéndolo como espacio de querella entre lo viejo y lo nuevo. Esos monstruos se ligan a la acuciante presencia del pasado reciente en la narrativa cinematográfica del cine de la primera década de la posdictadura argentina y se expresan en las temáticas de los filmes, en la construcción de los espacios o en los vínculos interpersonales que componen los primeros trazos de la(s) memoria(s) que desde el campo cultural comenzaban a escribirse.; Studies on Argentine cinema in the first post-dictatorship decade have often been approached in terms of polarization: opacity or transparency, continuity or rupture with previous cinema. Another interesting reading key to approach the audiovisual production of the decade may be its eminent transitional character. The cinema of those years, on the one hand, was witness and architect of the political transition between State terrorism and democracy; on the other hand, it was moved by the technological transition that imposed the advance of video as a new mode of production and circulation of images. At the same time, it experienced its own transition, which we will call cinematographic transition. The transition is presented as an interstice between the old and the new that intertwine to create forms that share characteristics of the past and the future without being completely identified with either of them. The coexistence -not without dispute- of narratives and modes of representation is a feature as frequent as it is distinctive. This paper seeks to investigate the monsters that inhabit the chiaroscuro of this cinema, constituting it as a space of conflict between the old and the new. These monsters are linked to the pressing presence of the recent past in the cinematic narrative of the first decade of the Argentine post-dictatorship and are expressed in the themes of the films, in the construction of the spaces or in the interpersonal links that make up the first traces of the memories that were beginning to be written from the cultural field.

Una teoría del Estado para la democracia argentina Nosetto, Luciano Ezequiel Más de una vez sostuvo Eduardo Rinesi que la Argentina de los años 80 dedicó los mayores esfuerzos de su imaginación política a pensar la transición a la democracia, soslayando sin embargo la reflexión sobre el Estado. Si bien los monográficos de Guillermo O’Donnell sobre el Estado burocrático autoritario y de Oscar Oszlak sobre la formación del Estado argentino se producen hacia fines del 70 y comienzos del 80, lo cierto es que, a poco de andar la nueva década, el desafío de transitar a la democracia termina atrayendo la mayoría de los esfuerzos intelectuales de la época. De allí que Cecilia Lesgart pueda afirmar que “la transición a la democracia sustituyó las reflexiones sobre el Estado latinoamericano”. Esta marca de origen explicaría en parte el hecho de que, 40 años después, contemos con robustas y sopesadas teorías de la democracia, pero que nos cueste todavía articular una teoría del Estado consistente.

Multiple challenges in the development of commercial crops using CRISPR/Cas technology Ayub, Nicolas Daniel; Soto, Gabriela Cynthia The CRISPR/Cas system is a highly efficient and versatile tool for editing plant genomes, with the potential to accelerate breeding programs and improve the sustainability of food production. Nevertheless, technical limitations delay the rapid spread of the CRISPR/Cas system benefits in agriculture. The natural features of plant species, including reproductive behavior, ploidy levels, genetic diversity, and generation times, can significantly impact the introgression of edited traits into elite germplasms. The production and selection of edited events require the same level of effort as those of their transgenic equivalents. Additionally, edited alleles tend to be recessive or not fully dominant, which differs from dominant transgenic events. To accelerate the introgression of edited events into conventional and transgenic varieties, we suggest utilizing edits on single-copy genes that induce dominant mutations. In the absence of new, simple traits that provide exceptional economic benefits for large companies, like herbicide tolerance in transgenic crops, we propose the emergence of particular public grants for edited variety productions, especially when the introgression shows a high level of technical feasibility. In the context of climate change, these public actions must be taken quickly to alleviate significant reductions in crop production.

Robust Molecular Anodes for Electrocatalytic Water Oxidation Based on Electropolymerized Molecular Cu Complexes Amthor, Sebastian; Ranu, Koushik; Bellido, Carlos G.; Salomón, Fernando Federico; Piccioni, Alberto; Mazzaro, Raffaello; Boscherini, Federico; Pasquini, Luca; Gil Sepulcre, Marcos; Llobet, Antoni A multistep synthesis of a new tetra-amidate macrocyclic ligand functionalized with alkyl-thiophene moieties, 15,15-bis(6-(thiophen-3-yl)hexyl)-8,13-dihydro-5H-dibenzo[b,h][1,4,7,10]tetraazacyclotridecine-6,7,14,16(15H,17H)-tetraone, H4L, is reported. The reaction of the deprotonated ligand, L4−, and Cu(II) generates the complex [LCu]2−, that can be further oxidized to Cu(III) with iodine to generate [LCu]−. The H4L ligand and their Cu complexes have been thoroughly characterized by analytic and spectroscopic techniques (including X-ray Absorption Spectroscopy, XAS). Under oxidative conditions, the thiophene group of [LCu]2− complex polymerizes on the surface of graphitic electrodes (glassy carbon disks (GC), glassy carbon plates (GCp), carbon nanotubes (CNT), or graphite felts (GF)) generating highly stable thin films. With CNTs deposited on a GC by drop casting, hybrid molecular materials labeled as GC/CNT@p-[LCu]2− are obtained. The latter are characterized by electrochemical techniques that show their capacity to electrocatalytically oxidize water to dioxygen at neutral pH. These new molecular anodes achieve current densities in the range of 0.4 mA cm−2 at 1.30 V versus NHE with an onset overpotential at ≈250 mV. Bulk electrolysis experiments show an excellent stability achieving TONs in the range of 7600 during 24 h with no apparent loss of catalytic activity and maintaining the molecular catalyst integrity, as evidenced by electrochemical techniques and XAS spectroscopy.

Melanoma cells with acquired resistance to vemurafenib have decreased autophagic flux and display enhanced ability to transfer resistance Perez, Celia Noemí; Falcón, Cristian Roberto; Delgado Mons, Johinna Ileana; Cuello Orlandi, Federico; Sangiacomo, Mercedes; Fernandez Muñoz, Juan Manuel; Guerrero, Martín; Benito Rodriguez, Paula Guadalupe; Colombo, Maria Isabel; Zoppino, Felipe Carlos Martin; Alvarez, Sergio Eduardo Over the last years, the incidence of melanoma, the deadliest form of skin cancer, has risen significantly. Nearly half of the melanoma patients exhibit the BRAFV600E mutation. Although the use of BRAF and MEK inhibitors (BRAFi and MEKi) showed an impressive success rate in melanoma patients, durability of response remains an issue because tumor quickly becomes resistant. Here, we generated and characterized Lu1205 and A375 melanoma cells resistant to vemurafenib (BRAFi). Resistant cells (Lu1205R and A375R) exhibit higher IC50 (5–6 fold increase) and phospho-ERK levels and 2–3 times reduced apoptosis than their sensitive parents (Lu1205S and A375S). Moreover, resistant cells are 2–3 times bigger, display a more elongated morphology and have a modulation of migration capacity. Interestingly, pharmacological inhibition of sphingosine kinases, that prevents sphingosine-1-phosphate production, reduces migration of Lu1205R cells by 50 %. In addition, although Lu1205R cells showed increased basal levels of the autophagy markers LC3II and p62, they have decreased autophagosome degradation and autophagy flux. Remarkably, expression of Rab27A and Rab27B, which are involved in the release of extracellular vesicles are dramatically augmented in resistant cells (i.e. 5–7 fold increase). Indeed, conditioned media obtained from Lu1205R cells increased the resistance to vemurafenib of sensitive cells. Hence, these results support that resistance to vemurafenib modulates migration and the autophagic flux and may be transferred to nearby sensitive melanoma cells by factors that are released to the extracellular milieu by resistant cells.

A Stochastic Detection Models Comparison in Turbulent Flow Events Calandra, Maria Valeria; Marañon Di Leo, Julio The need to establish the downwind fluid dynamic field of aerodynamic bodies subjected to a givenvelocity field is well known, to verify their aerodynamic characteristics. In this context, differenttechniques allow us to establish the characteristics of the field. It is almost always necessary to carry out quantitative determinations to describe the field correctly, particularly when the field is made up of turbulent wakes. In this sense, in the experimental field, it is common to use hot-wire anemometry techniques, which have great capabilities to quantify high-frequency events. Previous work has analyzed the determination of changes in hot-wire anemometry signals for the detection of events in turbulent flows with different models, based on stochastic algorithms (CPM - Change Point Model).The present work aims to compare the results obtained previously with the application of different CPM models developed. Previously applied and evaluated measurements are used, the implementation of the models is carried out and the results are compared. All the algorithms used can detect changes in data that do not have a known distribution, i.e. non-parametric distributions, which are typical for turbulent flow field signals. Measurements of the fluctuating components of the wind tunnel velocity at a specific point are considering. The signals used correspond to periodic detachments downstream of a flow control device (Gurney mini-flap) at the trailing edge of an airfoil. The results show which are the best models to use for the experimental detection of such turbulent events in the flow field.

Aspectos ecológicos parasitarios en Pleurodema nebulosum (Anura: Leptodactylidae) en la región del monte, San Juan, Argentina; Parasitic ecological aspects in Pleurodema nebulosum (Anura: Leptodactylidae) in the monte region, San Juan, Argentina Castillo, Gabriel Natalio; González Rivas, Cynthia Jesica; Acosta, Juan Carlos Pleurodema nebulosum es una especie con amplia distribución en Argentina. Se analizó el parasitismo y su relación con el sexo, perturbación humana, masa y tamaño corporal. Se identificó al nemátodo Aplectana nebulosa (Cosmocercidae) en el intestino largo. Encontramos que la abundancia media parasitaria se asoció positivamente con el tamaño (longitud hocico-cloaca), sexo macho y perturbación humana. Un mayor tamaño corporal condujo a un aumento de la abundancia media de parásitos. Los machos de ambos ambientes estaban más parasitados que hembras. La abundancia media de parásitos fue mayor en el ambiente perturbado en comparación con el control. Discutimos nuestros resultados en un contexto ecológico. Se provee información novedosa sobre el parasitismo en esta especie de anfibio en el desierto del monte de Argentina.; Pleurodema nebulosum is a species with a wide distribution in Argentina. Parasitism and its relationship with host sex, human disturbance, and body mass were assessed. The nematode Aplectana nebulosa (Cosmocercidae) was identified in the large intestine. Mean parasitic abundance was found to be positively associated with size (snout-vent length), male sex and human disturbance. Larger body size led to an increase in the mean abundance of parasites. Males in both environments were more parasitized than females. The mean abundance of parasites was higher in the disturbed environment compared to the control. We discuss our results in an ecological context. Novel information is provided on parasitism in this amphibian species in the Monte Desert, Argentina.

Novel Fluoroquinolones with Possible Antibacterial Activity in Gram-Negative Resistant Pathogens: In Silico Drug Discovery Coba Males, Manuel Alejandro; Lavecchia, Martín José; Alcívar León, Christian David; Santamaría Aguirre, Javier Antibiotic resistance is a global threat to public health, and the search for new antibacterial therapies is a current research priority. The aim of this in silico study was to test nine new fluoroquinolones previously designed with potential leishmanicidal activity against Campylobacter jejuni, Escherichia coli, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Salmonella typhi, all of which are considered by the World Health Organization to resistant pathogens of global concern, through molecular docking and molecular dynamics (MD) simulations using wild-type (WT) and mutant-type (MT) DNA gyrases as biological targets. Our results showed that compound 9FQ had the best binding energy with the active site of E. coli in both molecular docking and molecular dynamics simulations. Compound 9FQ interacted with residues of quinolone resistance-determining region (QRDR) in GyrA and GyrB chains, which are important to enzyme activity and through which it could block DNA replication. In addition to compound 9FQ, compound 1FQ also showed a good affinity for DNA gyrase. Thus, these newly designed molecules could have antibacterial activity against Gram-negative microorganisms. These findings represent a promising starting point for further investigation through in vitro assays, which can validate the hypothesis and potentially facilitate the development of novel antibiotic drugs.

Cosmogenic nuclide moraine chronologies from Patagonia: A globally synchronic response of mountain glaciers during Termination 1? Soteres, Rodrigo L.; Sagredo, Esteban; Kaplan, M.R.; Martini, Mateo Antonio; Riquelme, Fabian; Schaefer, J.M. Surface-exposure dating of moraines reveals that Patagonian glaciers fluctuated at the pulsebeat mimicked in polar ice cores from both hemispheres. These findings favor hypotheses that invoke coupled oceanic–atmospheric drivers to generate and propagate millennial-scale climate shifts during Termination 1.

Estrogens receptors, nuclear coactivator 1 and ligand-dependent corepressor expression are altered early during induced ovarian follicular persistence in dairy cattle Notaro, Ulises Sebastián; Huber, Emilia; Stassi, Antonela Florencia; Ormaechea, Nadia Estefanía; Chiaraviglio, Juan Alberto; Baravalle, María Eugenia; Ortega, Hugo Hector; Rey, Florencia; Salvetti, Natalia Raquel Failure of ovulation can lead to follicular persistence, one of the main components of the pathogenesis of cystic ovarian disease (COD) in dairy cattle. Follicular persistence causes the permanence of a functional follicular structure in the ovary, which alters the cyclicity of the female and causes infertility. The aim of the present study was to evaluate the expression of estrogen receptors (ESR) 1 and 2, and the coregulatory proteins NCOA1, NRIP1 and LCOR by immunohistochemistry, in antral and preovulatory/persistent follicles in a model of follicular persistence induced by low levels of progesterone, to detect incipient changes during COD development, on the expected day of ovulation (P0) and after 5 (P5), 10 (P10) and 15 (P15) days of follicular persistence. Twenty-five Holstein cows were used, which were distributed in 5 groups: control group (n = 5), group P0 (n = 5), group P5 (n = 5), group P10 (n = 5), group P15 (n = 5). ESR1 expression was lower in antral follicles of the P5 (theca), P10 and P15 (theca and granulosa) groups relative to the control group (p < 0.05), and also lower in granulosa cells of persistent follicles of the P5, P10 and P15 groups than in dominant follicles of the control group (p < 0.05), without differences in theca cells. ESR2 expression showed no differences between groups. The ESR1:ESR2 balance favored ESR2 expression along the development of persistent follicles, as from 5 days of persistence (p < 0.05). NCOA1 expression was higher in granulosa cells of both antral and persistent follicles from the P0 group relative to the P5 and P10 groups, but showed no differences with the control and P15 groups (p < 0.05). Theca cells of antral and persistent follicles showed higher expression in the P0 and P15 groups in relation to the control, P5 and P10 groups (p < 0.05). No differences were detected for NRIP1 in antral, dominant and persistent follicles between groups. LCOR expression showed a decrease in granulosa cells of antral follicles from all persistence groups relative to the control group (p < 0.05). In theca cells, antral follicles of the P10 group showed lower LCOR expression than the control group (p < 0.05). LCOR expression was similar for dominant and persistent follicles. Considering that the ESR1:ESR2 balance favored ESR2 expression along the development of persistent follicles, as well as the decreased LCOR and NCOA1 expression, we may assume that, at the early stages of persistence, there is a negative regulation of ESR transcription. This coincides with the effects of estrogens through ESR on proliferation and apoptosis among other processes that favor follicular persistence. The results obtained provide relevant information in the knowledge of local events during the development of follicular persistence that could explain the failures in the reversion of the disease through hormonal treatments and the high recurrence rates reported for COD. In addition, it contributes to the study and identification of possible therapeutic targets, for the design of new treatments.

Harmonic almost complex structures on almost abelian Lie groups and solvmanifolds Andrada, Adrián Marcelo; Tolcachier, Alejandro An almost abelian Lie group is a solvable Lie group with a codimension one normal abelian subgroup. We characterize almost Hermitian structures on almost abelian Lie groups where the almost complex structure is harmonic with respect to the Hermitian metric. Also, we adapt the Gray–Hervella classification of almost Hermitian structures to the family of almost abelian Lie groups. We provide several examples of harmonic almost complex structures in different Gray–Hervella classes on some associated compact almost abelian solvmanifolds.

Desarrollo de herramientas cuantitativas para asistir en la toma de decisiones médicas relacionadas a discapacidades motrices Catalfamo Formento, Paola Andrea Lucia; Bonell, Claudia Edith; Aldonate, Julio Alberto; Barrera, Verónica; Cherniz, Analía Soledad; Dutto, Cecar; García Añino, Eloisa; Merino, Gabriela Alejandra; Muñoz Larrosa, Eugenia Soledad; Ravera, Emiliano Pablo; Riveras, Mauricio Se define como discapacidad motriz a la disminución total o parcial de la movilidad en uno o más miembros del cuerpo. Las personas realizan tratamientos de rehabilitación motriz para su reinserción activa a la sociedad. Para evaluar el resultado de los tratamientos se requieren de herramientas objetivas, confiables, reproducibles y tecno-lógicamente accesibles para las instituciones de salud de la región. El objetivo de este trabajo fue desarrollar herramientas cuantitativas de la ingeniería que cumplan con estos requisitos.Para ello se estudiaron herramientas de análisis del movimiento humano, tales como parámetros espacio-temporales, despeje mínimo del pie, índices de gasto energético y método de análisis de presiones plantares. Además, para facilitar la implementación de herramientas en los ámbitos clínicos, se desarrollaron softwares que permiten el cálculo automático de los parámetros. Finalmente, se diseñaron e implementaron protocolos de análisis del movimiento humano en centros regionales dedicados a la rehabilitación motriz.Los resultados de este proyecto muestran que es posible desarrollar herramientas basadas en la cuantificación de parámetros biomecánicos y fisiológicos, provistas desde los distintos campos de la ingeniería biomédica, que resultan objetivas, confiables, reproducibles y tecnológicamente accesibles para las instituciones de salud de la región.

Redes de conocimiento en relación a agendas endógenas como alternativa a la tensión internacional-local; Knowledge networks in relation to endogenous agendas as an alternative to international-local tension Oregioni, María Soledad; Avondet, Laura; Durán, María Sol La ciencia y la tecnología han ganado relevancia en las agendas de política pública en la medida en que se las reconoce como componentes imprescindibles de cualquier estrategia que pretenda hacer frente a «desafíos actuales», muchos de los cuales son definidos como tales por los países del Norte global. Posicionadas desde el Sur global, y bajo el entendimiento de la no neutralidad de los conocimientos, indagamos sobre dinámicas de producción de conocimiento y nos cuestionamos si las temáticas en agenda responden a problemáticas situadas. El presente trabajo muestra cómo, a partir de la identificación de una problemática concreta –la producción de cannabis medicinal– fue posible generar redes de cooperación sur-sur formales e informales, integradas por diferentes actores (territoriales e inter-nacionales) en las que se habilitaron nuevas dinámicas de producción de conocimiento a partir de la convergencia de diferentes tipos de saberes y actores. Específicamente, se analizó como caso de estudio la producción de conocimiento sobre cannabis medicinal en la Universidad Nacional del Centro de la Provincia de Buenos Aires (UNICEN). Los resultados de la investigación permiten entender a la universidad como un actor fundamental en la producción de conocimiento y nos muestran cómo, a partir de una de sus funciones, la extensión, es posible crear nuevas dinámicas integrales de internacionalización en producción de conocimiento, destacando la importancia de las redes de cooperación sur-sur a la hora de dar respuesta a la tensión internacional-local en producción de conocimiento.; Science and technology have gained relevance in public policy agendas to the extent that they are recognized as essential components of any strategy that seeks to face «current challenges», many of which are defined as such by the countries of the global north. Positioned from the global South, and under the understanding of the non-neutrality of knowledge, we investigate the dynamics of knowledge production and question whether the topics on the agenda respond to situated problems. This paper shows how, based on the identification of a specific problem –the production of medical cannabis– it was possible to generate formal and informal South-South cooperation networks, made up of different actors (territorial and international) in which new dynamics of knowledge production from the convergence of different types of knowledge and actors. Specifically, the production of knowledge on medicinal cannabis at the National University of the Center of the Province of Buenos Aires (UNICEN) was analyzed as a case study. The results of the research allow us to understand the university as a fundamental actor in the production of knowledge; and they show us how from one of its functions, extension, it is possible to create new integral dynamics of internationalization in knowledge production, highlighting the importance of South-South cooperation networks when responding to tension international-local knowledge production.

How effective is camera trapping in monitoring grassland species in the southern Pampas ecoregion?; ¿Qué tan efectivo es el fototrampeo para el monitoreo de especies de pastizal en el sur de la ecorregión Pampas? Trofino Falasco, Clara; Simoy, Maria Veronica; Aranguren, Maria Florencia; Pizzarello, María Gimena; Cortelezzi, Agustina; Vera, David Gustavo; Simoy, Mario Ignacio; Marinelli, Claudia Beatriz; Cepeda, Rosana Esther; Di Giacomo, Adrian Santiago; Berkunsky, Igor We assessed the efficiency of camera trapping in monitoring bird and mammal species in the grasslands of Tandilia Mountains by calculating the naïve occupancy, capture rate, and time to the first detection for each species. We compared the observed richness with the reported richness from online databases. We performed species accumulation curves to estimate the sampling effort necessary to detect bird and mammal species. We detected 50 bird and 15 mammal species. The top 5 bird species (Chalk-browed Mockingbird, Rufous-collared Sparrow, Rufous Hornero, Great Pampa-Finch, and Spotted Nothura) accounted for 48% of all detected individual birds, with naïve occupancy of 21-25% and mean times for the first detection between 6 and 9 days. The top 5 mammal species (Pampas fox, large hairy armadillo, European hare, Molina’s hog-nosed skunk, and Geoffroy’s cat) accounted for 81% of all detected individual mammals, with naïve occupancy of 32-77% and mean times for the first detection between 4 and 7 days. A sampling effort of 2 weeks was the optimal balance between effort and result qualities. We detected all the reported richness of mammals and half of the reported grassland-associated birds. We provide valuable information for future grassland species monitoring with camera trapping in Neotropical grasslands.; Evaluamos la eficiencia del fototrampeo para monitorear aves y mamíferos en pastizales del sistema de Tandilia mediante la ocupación naïve, tasa de captura y tiempo hasta la primera detección de cada especie. Comparamos la riqueza observada con aquella reportada en bases de datos en línea. Realizamos curvas de acumulación de especies para estimar el esfuerzo de muestreo necesario para detectar la riqueza de especies. Detectamos 50 especies de aves y 15 de mamíferos. Las principales especies de aves (calandria común, chingolo, hornero, verdón e inambú campestre) representaron 48% de todas las detecciones de este grupo, con una ocupación naïve de 21-25% y tiempos promedios hasta la primera detección de entre 6 y 9 días. Las principales especies de mamíferos (zorro pampeano, peludo, liebre europea, zorrino y gato montés) contituyeron 81% de las detecciones de este grupo, con una ocupación naïve de 32- 77% y tiempos promedios hasta la primera detección de entre 4 y 7 días. Un muestreo de 2 semanas fue el balance óptimo entre esfuerzo y calidad de los resultados. Se detectó toda la riqueza reportada de mamíferos y la mitad de las aves asociadas a pastizales. Brindamos información valiosa para futuros monitoreos con fototrampeo en pastizales neotropicales.

Prediction of the physico-chemical properties of vegetable oils using optimal non-linear polynomials Alviso, Dario; Aguerre, Horacio Javier; Nigro, Norberto Marcelo; Artana, Guillermo Osvaldo Vegetable oils (VOs) comprise 90%–98% triglycerides (three fatty acids esters and glycerol), with trace amounts of mono-glycerides and di-glycerides. The content of glycerides in VOs can vary depending on the specific type of oil, the processing methods used, and other factors such as the cultivar and harvest date. VOs have been examined for usage in different applications due to their physicochemical properties, including stationary engines, big ships, and Diesel engines of low and medium speed. There are around 350 VOs that have the potential to be used as fuel sources, the vast majority of which have yet to have their physicochemical properties investigated. Regression models based purely on VOs fatty acid content are beneficial in this context. This study conducts a regression analysis of VOs density (DE), kinematic viscosity (KV), flash point (FP), and low and high heating values (LHV and HHV) as a function of their fatty acids. Several experimental databases were selected, including the values of VOs fatty acid composition and physico-chemical properties. Optimal non-linear polynomials were chosen for the regression procedure. Scheffé polynomials offer different fitting alternatives to adjust the VOs experimental databases using their five main fatty acids: from simple linear polynomials (including five terms) to full cubic polynomials (including 35 terms). The polynomials are validated by showing how well their results correspond with the experimental databases. The standard error values for the proposed full polynomials concerning the databases for DE, KV, FP, LHV, and HHV are 0.70%, 7.79%, 7.86%, 1.66%, and 0.19%, respectively.

Abordaje de la figura de Joaquín Víctor González a partir del análisis del patrimonio histórico cultural de la finca Samay Huasi (Chilecito, La Rioja); Approach to the Figure of Joaquín Víctor González from the Analysis of the Historical Cultural Heritage of the Samay Huasi Farm (Chilecito, La Rioja) Oliva, Camila; Sempe, Maria Carlota; Oliva, Fernando Walter Pablo A partir del estudio del patrimonio histórico y cultural de la Finca Samay Huasi -localizada en el distrito de San Miguel, municipalidad de Chilecito, La Rioja- analizamos la figura de Joaquín Víctor González, ilustre político, jurista educador y masón, cuyo accionar impactó profundamente en la conformación moderna de las instituciones del Estado argentino. Para ello partimos del estudio del patrimonio histórico y cultural de la Finca Samay Huasi propiedad de la Universidad Nacional de La Plata, ubicada en el distrito de San Miguel del departamento Chilecito, La Rioja. Los bienes culturales presentes en la misma poseen un importante valor patrimonial, material e inmaterial, sobre cuyos significados ahondamos en este escrito, para lo cual relevamos monumentos, placas y soportes conmemorativos emplazados en el predio, considerados como soportes de su memoria e identidad. Aquí presentamos su análisis y el de su obra escrita, así como los homenajes y artículos que trataron su figura, realizados por sus contemporáneos y generaciones posteriores. Su finca Samay Huasi, donada en vida a la Universidad Nacional de La Plata representa un patrimonio histórico, administrado por esta institución desde 1941. Esperamos que los resultados aquí expuestos aporten a la puesta en valor del patrimonio existente en la finca y a la apropiación de ese conocimiento por parte de la comunidad local.; From the study of the cultural historical heritage of Finca Samay Huasi, in the district of San Miguel, municipality of Chilecito, La Rioja, we analyze the figure of Joaquin Victor Gonzalez, illustrious politician, jurist, educator and freemason, whose actions profoundly affected the modern conformation of the institutions of the Argentine State. For this, we start from the study of the historical and cultural heritage of the Samay Huasi Farm owned by the National University of La Plata, located in the district of San Miguel of the Chilecito department, La Rioja. The cultural goods present in it have an important patrimonial, material and intangible value, on whose meanings we delve into in this writing, for which we relieve monuments, plaques and commemorative supports located on the property, considered as supports of their memory and identity. Here we present his analysis and that of his written work, as well as the tributes and articles that dealt with his figure, made by his contemporaries and later generations. His farm Samay Huasi, donated in life to the National University of La Plata represents a historical heritage, administered by this institution since 1941. We hope that the results presented here will contribute to the enhancement of the existing heritage on the farm and the appropriation of that knowledge by the local community.

Alteración térmica de artefactos líticos durante el Holoceno medio: Análisis de los conjuntos de Casa del Minero 1, Meseta Central de Santa Cruz; Thermal alteration of lithic artifacts during the middle Holocene: Analyses of the assemblages from Casa del Minero 1, Central Plateau of Santa Cruz Frank, Ariel David En este trabajo analizo los conjuntos líticos termoalterados de la unidad 3 superior de Casa del Minero 1 (Santa Cruz, Argentina), correspondiente al Holoceno medio. Investigo si se aplicó tratamiento térmico durante talla lítica y comparo los hallazgos con aquellos de los componentes finipleistocénicos del sitio. También estudio si otros procesos termoalteraron los conjuntos. Para ello, analizo la ubicación de los indicadores de termoalteración dentro de cada pieza, las características tecnomorfológicas de los artefactos y su distribución en la cueva.Los resultados indican que se aplicó el tratamiento térmico previo al retoque, durante la formatización final de instrumentos. Este procedimiento tendría características distintas a lo registrado para los componentes finipleistocénicos en términos de tipo de materia prima empleada y secuencias operativas en las cuales se implementó, con un uso menos frecuente que en momentos previos. Por otro lado, un grupo de artefactos pudo dañarse térmicamente por la acción de fuegos encendidos con posterioridad a la ocupación o bien por la caída accidental en fogones. No obstante, distintos procesos postdepositacionales habrían alterado la distribución de los restos y/o la conservación de las estructuras de combustión.; In this paper I study the thermally modified lithic assemblages from stratigraphic unit Upper 3, Casa del Minero 1 site (Santa Cruz, Argentina) which dates to the middle Holocene. I analyze if heat treatment was applied during flintknapping, and I compare the results with those obtained from the final Pleistocene layers of the site. I also study if other thermal processes have altered the assemblages. To achieve these goals, I analyze the location of thermal alteration traits within each artifact, the techno-morphological characteristics of the archaeological remains and their distribution within the cave. Results show that heat treatment was applied during the final shaping of tools, before retouch. This procedure had different characteristics to what has been recorded for the final Pleistocene layers, in terms of the kind of raw material used and the chaine operatoire in which it was applied. Furthermore, the use of heat treatment was less frequent during the middle Holocene. Apart from that, a group of artifacts could have become thermally damaged due to the action of fires lit after the occupation or else due to the accidental fall of lithics inside the hearths. However, different post-depositional processes might have modified the distribution of the remains and/or the conservation of the combustion structures.