The Oldest Beetle and Bee Ichnofossils from Mexico and their Paleoenvironmental Implications Guerrero Arenas, Rosalía; Jiménez Hidalgo, Eduardo; Genise, Jorge Fernando Specimens of Fictovichnus gobiensis, Celliforma curvata, Celliforma rosellii, Celliforma germanica and Celliforma isp. were collected from paleosol horizons in a fluviolacustrine succession near Santiago Yolomécatl town, in northwestern Oaxaca, southern Mexico. These ichnofossils represent the oldest evidence of beetles and bees in Mexican localities. K–Ar ages and the record of the equid Miohippus assiniboiensis, an index fossil, indicate that the age of the deposits is late Eocene. Based on the presence of the insect ichnofossils, pedogenic carbonate isotopes and mammal proxies, the inferred type of vegetation present in the study area was scrubland/woodland, within subhumid to subarid conditions.

Characterizing segregation in the Schelling–Voter model Caridi, Délida Inés; Pinasco, Juan Pablo; Saintier, Nicolas Bernard Claude; Schiaffino, Pablo In this work we analyze several aspects related with segregation patterns appearing in the Schelling–Voter model in which an unhappy agent can change her location or her state in order to live in a neighborhood where she is happy. Briefly, agents may be in two possible states, each one represents an individually-chosen feature, such as the language she speaks or the opinion she supports; and an individual is happy in a neighborhood if she has, at least, some proportion of agents of her own type, defined in terms of a fixed parameter T. We study the model in a regular two dimensional lattice. The parameters of the model are ρ, the density of empty sites, and p, the probability of changing locations. The stationary states reached in a system of N agents as a function of the model parameters entail the extinction of one of the states, the coexistence of both, segregated patterns with conglomerated clusters of agents of the same state, and a diluted region. Using indicators as the energy and perimeter of the populations of agents in the same state, the inner radius of their locations (i.e., the side of the maximum square which could fit with empty spaces or agents of only one type), and the Shannon Information of the empty sites, we measure the segregation phenomena. We have found that there is a region within the coexistence phase where both populations take advantage of space in an equitable way, which is sustained by the role of the empty sites.

Las cartas de la cárcel: una forma alternativa de testimoniar durante y después de la última dictadura argentina Guillard, Amandine Marie Este trabajo pretende echar luz sobre un aspecto poco conocido de la historia de las cárceles argentinas de la última dictadura (1976-1983): la correspondencia de los presos políticos. A la luz de un amplio corpus, tanto inédito como publicado, nos plantearemos la función de la "visibilización" y de la publicación de este material que tiende a hacerse cada vez más público. La enorme cantidad de cartas producidas durante aquel periodo nos obligará a realizar una selección del material tratando de dar a conocer tanto cartas de varones como de mujeres, escritas en distintos presidios del país y a distintos momentos de la dictadura. Si nuestra principal hipótesis se basa en el hecho de que constituyen un testimonio alternativo, nuestra tarea será demostrar en qué este testimonio excedió las fronteras espacio-temporales de las cárceles dictatoriales y de la esfera de lo íntimo para llegar a formar parte de la esfera pública y colectiva y a constituirse como un testimonio de alto valor para diversos sectores de la población.

Thinking in the sustainability of Nothofagus antarctica silvopastoral systems, how differ the responses of seedlings from different provenances to water shortage? Bahamonde, Héctor A.; Sánchez Gómez, D.; Gyenge, Javier Enrique; Peri, P. L.; Cellini, J. M.; Aranda, I. Nothofagus antarctica, is the most important species of the silvopastoral systems of southern Patagonia. However, there is limited information on the ecophysiological response mechanisms of seedlings for survival under different resource availability regimes, and whether such processes may differ between provenances. In this study, we evaluated the functional response to water shortage of seedlings of four N. antarctica provenances grown under controlled conditions. After an initial full irrigation period, seedlings were subjected to a water shortage cycle. Measurements of the diameter at the base of the stem, net photosynthesis (An), stomatal conductance to water vapour (gs), predawn water potential (Ψpd), osmotic potential at maximum and zero turgor (Π100; Π0), relative water content at zero turgor (RWC0) and maximum modulus of elasticity (Emax) were carried out during the experimental period. Differences between provenances concerning An and gs rates were recorded under full irrigation conditions, but were not detected in association with drought stress. All provenances had similar osmotic potential values (Π100 and Π0) at full irrigation, but water shortage led to significant osmotic potential differences between provenances. During the whole experimental period, no significant differences on RWC0 and Emax values were recorded among provenances. Under full irrigation conditions, all N. antarctica provenances had a similar physiological performance which suggests that environmental conditions may be the main driver for phenotypic differences in this species. From the osmotic adjustment results gathered, it is derived that a major osmoregulation capacity in response to water shortage is a common feature of all the N. antarctica provenances evaluated.

Bone regeneration mediated by a bioactive and biodegradable extracellular matrix-like hydrogel based on elastin-like recombinamers Coletta, Dante Jesus; Ibáñez Fonseca, Arturo; Missana, Liliana Raquel; Jammal, María Victoria; Vitelli, Ezequiel J.; Aimone, Mariangeles; Zabalza, Facundo; Issa, João P. Mardegan; Alonso, Matilde; Rodríguez Cabello, José Carlos; Feldman, Sara The morbidity of bone fractures and defects is steadily increasing due to changes in the age pyramid. As such, novel biomaterials that are able to promote the healing and regeneration of injured bones are needed to overcome the limitations of auto-, allo-, and xenografts, while providing a ready-To-use product that may help to minimize surgical invasiveness and duration. In this regard, recombinant biomaterials, such as elastin-like recombinamers (ELRs), are very promising as their design can be tailored by genetic engineering, thus allowing scalable production and batch-To-batch consistency, among others. Furthermore, they can self-Assemble into physically crosslinked hydrogels above a certain transition temperature, in this case body temperature, but are injectable below this temperature, thereby markedly reducing surgical invasiveness. In this study, we have developed two bioactive hydrogel-forming ELRs, one including the osteogenic and osteoinductive bone morphogenetic protein-2 (BMP-2) and the other the Arg-Gly-Asp (RGD) cell adhesion motif. The combination of these two novel ELRs results in a BMP-2-loaded extracellular matrix-like hydrogel. Moreover, elastase-sensitive domains were included in both ELR molecules, thereby conferring biodegradation as a result of enzymatic cleavage and avoiding the need for scaffold removal after bone regeneration. Both ELRs and their combination showed excellent cytocompatibility, and the culture of cells on RGD-containing ELRs resulted in optimal cell adhesion. In addition, hydrogels based on a mixture of both ELRs were implanted in a pilot study involving a femoral bone injury model in New Zealand white rabbits, showing complete regeneration in six out of seven cases, with the other showing partial closure of the defect. Moreover, bone neoformation was confirmed using different techniques, such as radiography, computed tomography, and histology. This hydrogel system therefore displays significant potential in the regeneration of bone defects, promoting self-regeneration by the surrounding tissue with no involvement of stem cells or osteogenic factors other than BMP-2, which is released in a controlled manner by elastase-mediated cleavage from the ELR backbone.

Reforma agraria y práctica política en el contexto del desarrollo y la modernización, Argentina 1955-1975; Agrarian Reform and Political Practice in the Context of Development and Modernization, Argentina, 1955-1975 Lazzaro, Silvia Beatriz El propósito es el estudio de los proyectos de reforma agraria en Argentina durante el periodo de la expansión capitalista de posguerra y frente al intento de redefinición del proceso de acumulación con el retorno del peronismo, sus condicionantes internacionales y locales, y sus resultados. Nuestra hipótesis sostiene que todos los intentos de la reforma agraria, de los diferentes regímenes políticos del periodo, tuvieron como fin primordial garantizar el predominio de la concentración de la tierra, alejados de toda pretensión de índole redistribucionista. En la estrategia metodológica tiene preeminencia el análisis cualitativo. Ello con base en la consulta, el análisis y la crítica de la bibliografía de la época y la actual, fuentes oficiales, publicaciones periódicas sobre temas rurales, y de las corporaciones agrarias, en el marco de un cometido central que apunta al conocimiento de procesos escasamente abordados desde la historia de manera integral.; The purpose is the study of the agrarian reform projects in Argentina during the period of the post-war capitalist expansion and the attempt to redefine the process of accumulation with the return of peronism; their international and local conditions; and their results. Our hypothesis argues that all the attempts of the agrarian reform, present in the agenda of the different political regimes of the period, had as primary aim to guarantee the predominance of the concentration of the land, away from any pretension of redistribution. In the methodological strategy, the qualitative analysis has preeminence. This is based on the consultation, analysis and criticism of current and current bibliography, official sources, periodicals on rural issues, and agrarian corporations. All this in the context of a central task that aims to the knowledge of processes that have been scarcely approached from History in an integral way.

Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery Clemente, Tiago; Vieira, Narcisio J.; Cerliani, Juan Pablo; Adrain, Colin; Luthi, Alexander; Dominguez, Mariana; Yon, Monica; Barrence, Fernanda C.; Riul, Thalita B.; Cummings, Richard D.; Zorn, Thelma; Amigorena, Sebastian; Dias Baruffi, Marcelo; Rodriguez, Mauricio M.; Seamus, J. Martin; Rabinovich, Gabriel Adrián; Amarante Mendez, Gustavo P. Secretory granules released by cytotoxic T lymphocytes (CTLs) are powerful weapons against intracellular microbes and tumor cells. Despite significant progress, there is still limited information on the molecular mechanisms implicated in target-driven degranulation, effector cell survival and composition and structure of the lytic granules. Here, using a proteomic approach we identified a panel of putative cytotoxic granule proteins, including some already known granule constituents and novel proteins that contribute to regulate the CTL lytic machinery. Particularly, we identified galectin-1 (Gal1), an endogenous immune regulatory lectin, as an integral component of the secretory granule machinery and unveil the unexpected function of this lectin in regulating CTL killing activity. Mechanistic studies revealed the ability of Gal1 to control the non-secretory lytic pathway by influencing Fas?Fas ligand interactions. This study offers new insights on the composition of the cytotoxic granule machinery, highlighting the dynamic cross talk between secretory and non-secretory pathways in controlling CTL lytic function.

Reductive amination of levulinic acid to different pyrrolidones on Ir/SiO2-SO3H: Elucidation of reaction mechanism Martínez, José J.; Silva, Leonardo; Rojas, Hugo A.; Romanelli, Gustavo Pablo; Santos, Lucas A.; Ramalho, Teodorico C.; Brijaldo, María H.; Passos, Fabio B. Levulinic acid (LA) transformation to different pyrrolidones via reductive amination was studied using an Ir/SiO2-SO3H catalyst in liquid phase. The effects of solvent, amine concentration, H2 partial pressure, catalyst mass, and reuse were studied. The spent catalysts were evaluated by DRIFTS to obtain evidence of the interaction of levulinic acid with aniline on the catalyst surface. The sulfonic groups on SiO2 improved the yield to pyrrolidones and avoided side reactions. A reaction mechanism is proposed where the reductive amination occurs between LA and amine towards an intermediate amine that is then cycled. The Gibbs free energy for the reaction mechanism was evaluated. Besides, the HOMO and LUMO of the amine reactants and intermediates using density functional theory (DFT) with the B3LYP-D3 method were theoretically determined to understand the rate-limiting and the cyclization steps.

Manifest ambiguity: Intermediate forms, variation, and mammal paleontology in Argentina, 1830–1880 Podgorny, Irina This paper presents the impact of diverse aspects of Darwin's works on the practices of mammal paleontology in different moments of nineteenth-century Argentina. Starting with Darwin through the publications of Florentino Ameghino, it shows the extraordinary complexity of systematic paleontology that characterized the second half of the nineteenth century. Neither “natural selection” nor “struggle for life” seemed to have shaped the practices of vertebrate paleontology in Argentina. Darwin's earlier work as a voyageur and geologist together with later concerns about intermediate forms and variation allow for an assessment of the impact of Darwin's work on the practice of paleontology in Argentina.

Cash transfers and female labor force participation: the case of AUH in Argentina Garganta, Santiago; Gasparini, Leonardo Carlos; Marchionni, Mariana In this paper, we estimate the impact on female labor force participation of a massive conditional cash transfer program—Universal Child Allowance, AUH—launched in Argentina in 2009. We identify the intention-to-treat effect by comparing eligible and non-eligible women over time through a diff-in-diff methodology. The results suggest a negative and economically significant effect of the program on female labor force participation. The disincentive to participate is present for married women, while the effect is not statistically significant for unmarried women with children. We also find evidence on the heterogeneity of the effect depending on woman’s education, husband’s employment status, number and age of children, and whether the woman is the main responsible of domestic chores. The relatively large value of the benefit and the fact that transfers are mostly directed to mothers may explain the sizeable effect of the program on female labor supply. The welfare implications of the results are not clear and deserve further inspection. JEL Classification: H53, I38, J16, J22.

Nanotoxicological and teratogenic effects: A linkage between dendrimer surface charge and zebrafish developmental stages Calienni, Maria Natalia; Feas, Daniela Agustina; Igartúa, Daniela; Chiaramoni, Nadia Silvia; Alonso, Silvia del Valle; Prieto, Maria Jimena This article reports novel results about nanotoxicological and teratogenic effects of the PAMAM dendrimers DG4 and DG4.5 in zebrafish (Danio rerio). Zebrafish embryos and larvae were used as a rapid, high-throughput, cost-effective whole-animal model. The objective was to provide a more comprehensive and predictive developmental toxicity screening of DG4 and DG4.5 and test the influence of their surface charge. Nanotoxicological and teratogenic effects were assessed at developmental, morphological, cardiac, neurological and hepatic level. The effect of surface charge was determined in both larvae and embryos. DG4 with positive surface charge was more toxic than DG4.5 with negative surface charge. DG4 and DG4.5 induced teratogenic effects in larvae, whereas DG4 also induced lethal effects in both zebrafish embryos and larvae. However, larvae were less sensitive than embryos to the lethal effects of DG4. The platform of assays proposed and data obtained may contribute to the characterization of hazards and differential effects of these nanoparticles.

New insights into Trypanosoma cruzi evolution, genotyping and molecular diagnostics from satellite DNA sequence analysis Ramirez Gomez, Juan Carlos; Torres, Carolina; Curto, Maria de Los Angeles; Schijman, Alejandro Gabriel Trypanosoma cruzi has been subdivided into seven Discrete Typing Units (DTUs), TcI-TcVI and Tcbat. Two major evolutionary models have been proposed to explain the origin of hybrid lineages, but while it is widely accepted that TcV and TcVI are the result of genetic exchange between TcII and TcIII strains, the origin of TcIII and TcIV is still a matter of debate. T. cruzi satellite DNA (SatDNA), comprised of 195 bp units organized in tandem repeats, from both TcV and TcVI stocks were found to have SatDNA copies type TcI and TcII; whereas contradictory results were observed for TcIII stocks and no TcIV sequence has been analyzed yet. Herein, we have gone deeper into this matter analyzing 335 distinct SatDNA sequences from 19 T. cruzi stocks representative of DTUs TcI-TcVI for phylogenetic inference. Bayesian phylogenetic tree showed that all sequences were grouped in three major clusters, which corresponded to sequences from DTUs TcI/III, TcII and TcIV; whereas TcV and TcVI stocks had two sets of sequences distributed into TcI/III and TcII clusters. As expected, the lowest genetic distances were found between TcI and TcIII, and between TcV and TcVI sequences; whereas the highest ones were observed between TcII and TcI/III, and among TcIV sequences and those from the remaining DTUs. In addition, signature patterns associated to specific T. cruzi lineages were identified and new primers that improved SatDNA-based qPCR sensitivity were designed. Our findings support the theory that TcIII is not the result of a hybridization event between TcI and TcII, and that TcIV had an independent origin from the other DTUs, contributing to clarifying the evolutionary history of T. cruzi lineages. Moreover, this work opens the possibility of typing samples from Chagas disease patients with low parasitic loads and improving molecular diagnostic methods of T. cruzi infection based on SatDNA sequence amplification

Letter to the editor: Longitudinal stability of neurocognitive subtypes in bipolar disorder Martino, Diego Javier; Scápola, María; Strejilevich, Sergio

Milagros, Prodigios y Magia en el Poema de Alfonso Onceno Janin, Erica Noemi En este trabajo nos proponemos estudiar la funcionalidad de diversos elementos sobrenaturales relacionados a lo milagroso, lo mágico y lo prodigioso en el Poema de Alfonso Onceno para demostrar que el uso de estos elementos vinculados a Alfonso XI cumpliría una función laudatoria y propagandística no solo de su figura regia sino también de su proyecto político.

Dos “fuas” en los años setenta: El movimiento estudiantil en las postrimerías de la “Revolución Argentina”; Two “fuas” in the seventies: The student movement in the aftermath of the “Argentine Revolution” Califa, Juan Sebastián A fines de 1970 los comunistas dieron vida en LaPlata a una nueva Federación Universitaria Argentina(FUA) que confrontó con la FUA ya existente,cuyo congreso sesionó poco después en Córdoba.En esta segunda federación se destacarían los mao-ístas del FAUDI, los socialistas del MNR, los militantesde la izquierda nacional del PSIN y los radicales,socialistas y anarquistas, con creciente pesode los primeros, de la Franja Morada. En este artículome propongo reconstruir la trayectoria deambas federaciones, atendiendo a los debates quemantuvieron en momentos donde la dictaduraautoproclamada ?Revolución Argentina? se encontrabaen retirada. Se pretende ofrecer una síntesisgeneral del estado de situación del movimientoestudiantil argentino y de sus principales agrupaciones.Para ello, se recurrirá a documentos deambas federaciones, hasta ahora no abordados, asícomo a revistas de la prensa partidaria y comercialdel período y la literatura en cuestión.; At the end of 1970 the communists gave life in La Plata to a new Argentine University Federation (FUA) that confronted with the existing FUA, whose congress was soon to be held in Cordoba. In this second federation, the maoists of the FAUDI, the socialists of the MNR, the militants of the national left of the PSIN and the radicals, socialists and anarchists, with growing weight of the first, of the Franja Morada would stand out. In this article I rebuild the history of both federations, taking into account the debates they had in moments when the self-proclaimed dictatorship "Argentine Revolution" was in retreat. It aims to provide a general synthesis of the state of the Argentine student movement and its main groups. To do so, we will use documents from both federations, hitherto unaddressed, as well as magazines from the party and commercial press of the period and literature in question.

Filiaciones incómodas y subjetividad: una lectura de Los Topos, de Félix Bruzzone; Una misma noche, de Leopoldo Brizuela y Una muchacha muy bella, de Julián López; Uncomfortable filiations and subjectivity: a reading of Los Topos (F. Bruzzone); Una misma noche (L. Brizuela) and Una muchacha muy bella (J. López) Daona, Victoria Este artículo indaga en los procesos de conformación de las subjetividades frente a experiencias de filiación traumáticas en la infancia, a partir de analizar Los Topos (2008) de Félix Bruzzone, Una misma noche (2012) de Leopoldo Brizuela y Una muchacha muy bella (2014) de Julián López. En estos tres casos los narradores se posicionan como hijos que esquivan o cuestionan el accionar de sus padres y madres durante los años ‘70, a la vez que construyen una posición que pretende estar desligada de ese pasado familiar. Sin embargo, ninguno lo logra puesto que las marcas del pasado vuelven en el presente asumiendo distintas formas, lo que nos permite hablar de filiaciones incómodas que inciden fuertemente en la conformación de las subjetividades de cada narrador.; This article investigates in the processes of conformation of the subjectivities in front of experiences of traumatic filiations in the childhood, from analyzing Los Topos (2008) by Felix Bruzzone, Una misma noche (2012) by Leopoldo Brizuela and Una muchacha muy bella (2014) by Julián López. In these three cases, the narrators position themselves as children who dodge or question the actions of their parents during the 1970s and at the same time construct a position that pretends to be disconnected from that family past. However, none of them succeed because the marks of the past return in the present assuming different forms, which allows us to speak of uncomfortable filiations that strongly influence the conformation of the subjectivities of each narrator.

Lo sobrenatural como impronta monástico-clerical en el Poema de Fernán González Alcatena, María Eugenia El Poema de Fernán González fue compuesto, según diversas estimaciones, entre 1250 y 1275. Se conjetura que su autor fue un clérigo vinculado al monasterio de San Pedro de Arlanza, en Hortigüela1 . El Poema reelabora en torno a la figura de Fernán González varias tradiciones y materiales previos –épicos (entre ellos, de acuerdo con gran parte de la crítica, un cantar sobre el propio conde, del que solo se habrían conservado testimonios indirectos), folklóricos, clericales, cronísticos, hagiográficos, monacales– y entrelaza de manera indisociable la gesta del héroe con la fundación, la protección y la injerencia del monasterio, con la voluntad notoria de prestigiar a este último y promover sus intereses por sobre los de otros cenobios cercanos. En estos dos aspectos, es necesario considerar el poema clerical como un punto de llegada2 que recoge, reelabora y se hace eco de relatos preexistentes, ya en circulación, con la intención de forjar una prosa superadora, consagrada con la autoridad que otorga la grand maestría del mester. Tomando estas consideraciones como marco, el presente trabajo se propone trazar una visión panorámica y sucinta del conjunto de elementos sobrenaturales y prodigiosos que aparecen en el relato, apuntando sus rasgos esenciales y su inserción en el argumento general, con el propósito de destacar, finalmente, su relevancia en la orientación monástico-clerical de la materia tradicional, donde cumplen un rol fundamental.

PRP en medicina regenerativa: fundamento biológico, preparación y clasificación Etulain, Julia Si bien las plaquetas son ampliamente reconocidaspor su rol clave en la hemostasia y la trombosis, numerosasevidencias han demostrado que estas células tambiénmodulan otros procesos fisiopatológicos incluyendola inflamación y la regeneración de tejidos. Estos fenómenosestán mediados por la liberación de factoresde crecimiento, citoquinas y moduladores de la matrizextracelular que promueven secuencialmente larevascularización del tejido dañado, la restauración deltejido conectivo y la regeneración de las células específicasde cada tejido. Por este motivo, los derivados deplasma rico en plaquetas (PRP) se emplean en medicinaregenerativa para el tratamiento de diversas situacionesclínicas incluyendo úlceras, quemaduras, reparaciónmuscular, ósea y recuperación de tejido postquirúrgica.Sin embargo, a pesar de las diversas aplicaciones, laeficacia de estos tratamientos está asociada a diversascontroversias causadas por la escasez de ensayos clínicoscontrolados y aleatorizados que prueben su eficacia,la falta de regulación y control en la implementaciónde estas terapias y la ausencia de consenso en las técnicasde preparación de PRP. En esta revisión se describenlos fundamentos biológicos subyacentes al uso deestos tratamientos, los diversos métodos de preparacióny aplicación de estos hemocomponentes, como asítambién las controversias y perspectivas futuras vinculadasal empleo del PRP en medicina regenerativa.

Hipercorrección grafémica en importaciones léxicas: Datos del español bonaerense; Hipercorrecció grafèmica en importacions lèxiques: Dades de l’espanyol de Buenos Aires; Graphemic hypercorrection in lexical imports: Data from Buenos Aires Spanish Hipperdinger, Yolanda Haydee Sobre la base de datos recogidos en el área dialectal bonaerense del español de la Argentina, analizamos en este artículo la hipercorrección encontrada en la escritura de importaciones léxicas provenientes de lenguas europeas de carácter internacional. Observamos que dicha hipercorrección asume casi exclusivamente la forma de una amplificación grafémica que, a su vez, consiste generalmente en una duplicación consonántica. Exploramos las razones de esa preferencia y concluimos que se debe a que la amplificación registrada no oscurece la relación con las respectivas realizaciones orales más extendidas,así como que en todos los casos los recursos empleados en la "exageración" referida forman efectivamente parte de las convenciones de las lenguas donantes, por lo que no implican otra innovación que la posicional.; En aquest article analitzem la hipercorrecció verificada en l’escriptura d’importacions lèxiques provinents de llengües europees de caràcter internacional a partir d’escrits obtinguts de la base de dades que recull textos de l’àrea dialectal de Buenos Aires de l’espanyol de l’Argentina. Observem que aquesta hipercorrecció assumeix gairebé exclusivament la forma d’una amplificació grafèmica que, al seu torn, consisteix generalment en una duplicació consonàntica. Explorem les raons d’aquesta preferència i concloem que es deu al fet que l’amplificació registrada no enfosqueix la relació amb les respectives realitzacions orals més esteses. També hem observat que en tots els casos els recursos emprats en l’“exageració” referida formen efectivament part de les convencions de les llengües donants, de manera que no impliquen una altra innovació que la posicional.; We analyze in this article hypercorrection found in the writing of lexical imports from European languages of international level. The analysis is made on the basis of writings obtained from the database that includes texts from the dialectal area of Buenos Aires Spanish. We observe that such hypercorrection almost exclusively takes the form of a graphemic amplification that, in turn, generally consists of a consonant duplication. We explore the reasons for this preference and conclude that the registered amplification is preferred because it does not darken the relationship with the respective most widespread oral realizations. We have also observed that in all cases the resources used in the referred “exaggeration” are effectively part of the conventions of donor languages, so they do not involve another innovation but the positional one.

Three explanatory hypotheses of the correlation between hypertension and cognitive impairment. Current data analysis and future prospects; Tres hipótesis explicativas de la correlación entre hipertensión y deterioro cognitivo. Análisis de la producción actual y perspectivas futuras; Três hipoteses explicativas da correlação entre hipertensão e deterioro cognitivo. Análise da produção atual e perspectivas futuras Bruno, Franco; Alfonso, Guillermo; Martino, Pablo; Cervigni, Mauricio Alejandro La prevalencia de patologías relacionadas con hipertensión se está incrementando en el total de la población. Este fenómeno parece estar relacionado con el envejecimiento poblacional, provocando también un incremento en los tratamientos con medicación crónica. El costo de los tratamientos crónicos aumentó en este rango etario provocando una anticipación de los cambios demográficos previstos. Objetivo: Revisar artículos empíricos concernientes a la correlación entre hipertensión y deterioro cognitivo publicados en base de datos digitales, con el propósito de reunir los conocimientos actuales e identificar posibles caminos para futuras investigaciones. Resultados: La correlación entre esos dos términos es resumida en tres explicaciones teóricas, observando: 1) deterioro cognitivo como desorden comórbido de trastornos hipertensivos, 2) deterioro cognitivo como consecuencia del daño cerebral provocado por hipertensión, y 3) deterioro cognitivo como efecto indeseable de la medicación antihipertensiva. Conclusiones: Los resultados pretenden brindar una visión general del impacto de la hipertensión en el desempeño cognitivo en sus diferentes niveles; al mismo tiempo, formular objetivos para nuevas investigaciones tendientes a clarificar y mejorar estas elucidaciones teóricas.; A prevalência de patologias relacionadas com a hipertensão está incrementando no total da população. Este fenômeno parece estar relacionado com o envelhecimento populacional, provocando também um incremento nos tratamentos com medicação crônica. O custo dos tratamentos crônicos aumentou neste rango etário provocando uma antecipação dos câmbios demográficos previstos. Objetivo: Revisar artigos empíricos concernentes à correlação entre hipertensão e deterioro cognitivo publicados em base de dados digitais, com o propósito de reunir os conhecimentos atuais e identificar possíveis caminhos para futuras investigações. Resultados: A correlação entre esses dois termos é resumida em três explicações teóricas, observando: 1) deterioro cognitivo como desordem comórbido de transtornos hipertensivos, 2) deterioro cognitivo como consequência do dano cerebral provocado por hipertensão, e 3) deterioro cognitivo como efeito indesejável da medicação anti-hipertensiva. Conclusões: Os resultados pretendem brindar uma visão geral do impacto da hipertensão no desempenho cognitivo em seus diferentes níveis; ao mesmo tempo, formular objetivos para novas investigações tendentes a clarificar e melhorar estas elucidações teóricas.; Prevalence of hypertension related disorders isincreasing on the total population. This phenomenonseems to be connected to population ageing and hasled to an increment of chronic drug treatments. Thecost of chronic treatment in this age group will increase,given the demographic changes that are anticipated.Objective: To revise empirical articles concerningto correlation between hypertension and cognitiveimpairment published in digital databases, respondingto the purpose of collect current knowledge and identifypossible pathways for future research. Results: Thecorrelation between these two terms is summarized inthree theoretical explanations, watching: 1) cognitiveimpairment as a comorbid disorder with hypertensivediseases, 2) hypertension as a brain damage causal thatlead to cognitive impairment, and 3) cognitive impairment as an undesirable effect of antihypertensive medication.Conclusions: Results pretend to provide an overview about theimpact of hypertension on cognitive performance at differentlevels, and to formulate objectives for new investigations thatcould clarify and improve these theoretical elucidations.