Modified natural mineral with a biogenic compound to control microbial growth in waterborne paint Barberia Roque, Leyanet; Lopez, Guillermo Pablo; Gámez Espinosa, Erasmo Junior; Igal, Katerine; Fernandez, Mariela Alejandra; Deyá, Cecilia; Bellotti, Natalia Hygienic paints are designed to control microbial growth by imparting antimicrobial activity both in-film and incan. Biogenic compounds like terpenes in essential oils (EOs) have potential antimicrobial properties. Additionally, modified montmorillonites (Mt) show promise as nanoscale carriers for these compounds. This research aimed to obtain a functionalized antimicrobial montmorillonite hybrid to be applied in the formulation of bioactive paints. The biogenic compounds evaluated were the essential oils of white thyme and mint, to be applied for the first time in hygienic coatings. A soybean derivative was used as an organic modifier of the clay mineral. The synthesized hybrids were characterized by Fourier-Transform Infrared (FTIR) spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and energy dispersive spectrometer (EDS). Bioassays were carried out against fungal strains including Cladosporium cladosporioides, Chaetomium globosum, and Aspergillus versicolor, as well as bacterial strains such as Staphylococcus aureus and Escherichia coli. White thyme was the EO with the higher antimicrobial activity. Added to this, white thyme oil managed to impart its antimicrobial activity to the synthesized hybrid. The formulated paints with 0.75 concentration of pigment per volume (PVC) efficiently prevented in-can pollution.

Low-cost algorithms for clinical notes phenotype classification to enhance epidemiological surveillance: A case study Petri, Javier; Barcena Barbeira, Pilar; Pesce, Martina; Xhardez, Verónica; Laje, Rodrigo; Cotik, Viviana Erica Objective:Our study aims to enhance epidemic intelligence through event-based surveillance in an emerging pandemic context. We classified electronic health records (EHRs) from La Rioja, Argentina, focusing on predicting COVID-19-related categories in a scenario with limited disease knowledge, evolving symptoms, non-standardized coding practices, and restricted training data due to privacy issues.Methods:Using natural language processing techniques, we developed rapid, cost-effective methods suitable for implementation with limited resources. We annotated a corpus for training and testing classification models, ranging from simple logistic regression to more complex fine-tuned transformers.Results:The transformer-based, Spanish-adapted models BETO Clínico and RoBERTa Clínico, further pre-trained with an unannotated portion of our corpus, were the best-performing models (F1= 88.13% and 87.01%). A simple logistic regression (LR) model ranked third (F1=85.09%), outperforming more complex models like XGBoost and BiLSTM. Data classified as COVID-confirmed using LR and BETO Clínico exhibit stronger time-series Pearson correlation with official COVID-19 case counts from the National Health Surveillance System (SNVS 2.0) in La Rioja province compared to the correlations observed between the International Code of Diseases (ICD-10) codes and the SNVS 2.0 data (0.840, 0.873, and 0.663, p-values < 3x10^-7). Both models have a good Pearson correlation with ICD-10 codes assigned to the clinical notes for confirmed (0.940 and 0.902) and for suspected cases (0.960 and 0.954), p-values < 3x10^-18.Conclusion:This study shows that simple, resource-efficient methods can achieve results comparable to complex approaches. BETO Clínico and LR strongly correlate with official data, revealing uncoded confirmed cases at the pandemic’s onset. Our results suggest that annotating a smaller set of EHRs and training a simple model may be more cost-effective than manual coding. This points to potentially efficient strategies in public health emergencies, particularly in resource-limited settings, and provides valuable insights for future epidemic response efforts.

Psychometric properties analysis of the Motivational Self-Regulation Strategies Questionnaire; Análisis de las propiedades psicométricas del Cuestionario de Estrategias de Autorregulación Motivacional; Análise das propriedades psicométricas do Questionário de Estratégias de Autorregulação Motivacional Freiberg Hoffmann, Agustín; Motta, Florencia Anabel; Tisocco, Franco; Sánchez Rosas, Javier Motivational self-regulation allows students tosustain and/or improve their motivation to achieve their goals. Thisself-regulation variant is related to variables such as academic performance,classroom climate, and academic procrastination, among others. The MotivationalSelf-Regulation Strategies Questionnaire (MRSQ) operationalized the construct. Thequestionnaire was adapted in Córdoba (Argentina), dividing the dimensions ofgoal regulation according to the strategies employed ­— whether by approximationor avoidance. The present research proposes to analyze new evidence of thevalidity and reliability of the MRSQ. A total of 412 university students fromBuenos Aires (Argentina) participated in the study. The analysis of theinternal structure of the instrument using confirmatory factor analysis (CFA)and exploratory structural equation modeling (ESEM) verified a better fit forthe 8-factor model. Further, a measurement invariance analysis between samplesof students from Buenos Aires and Córdoba verified the metric equivalence ofthe MRSQ. The internal consistency of the dimensions was adequate (> .70).Next, the concurrent validity test yielded positive and significantcorrelations with learning approaches and negative correlations with academicprocrastination. Statistical norms were also computed. This work provides newevidence on the psychometric properties of the MRSQ and norms that enable itsuse and interpretation within applied settings.; La autorregulación motivacional permite a los estudiantes sostener o mejorar su motivación para alcanzar sus metas. Esta autorregulación se relaciona con variables relevantes como el rendimiento académico, el clima de clase y la procastinación académica, entre otras. El Cuestionario de Estrategias de Autorregulación Motivacional (CEAM) operacionaliza el constructo y fue adaptado en Córdoba (Argentina), dividiendo las dimensiones de regulación de metas según las estrategias empleadas sean por aproximación o evitación. Esta investigación propone analizar nuevas evidencias de validez y confiabilidad del CEAM. Participaron 412 estudiantes universitarios de Buenos Aires (Argentina). El análisis de la estructura interna del instrumento mediante análisis factorial confirmatorio (AFC) y el análisis de ecuaciones estructurales exploratorio (ESEM) verificaron el mejor ajuste para el modelo de ocho factores. Luego, un análisis de invarianza factorial entre muestras de estudiantes de Buenos Aires y Córdoba verificó la equivalencia métrica del CEAM. La consistencia interna de las dimensiones fue adecuada (> .70). Seguidamente, el examinen de validez concurrente arrojó correlaciones positivas y significativas con los enfoques de aprendizaje, y negativas con la procastinación académica. También se estimaron normas estadísticas. Este trabajo proporciona nuevas evidencias sobre las propiedades psicométricas del CEAM y baremos que posibilitan su uso e interpretación dentro del campo de aplicación.; A autorregulação motivacional permite aos estudantes manterem e/ou melhorarem sua motivação para alcançar suas metas. Essa autorregulação está relacionada com variáveis relevantes, como o desempenho acadêmico, o clima de sala de aula e a procrastinação acadêmica, entre outras. O Questionário de Estratégias de Autorregulação Motivacional (QEAM) operacionaliza o construto e foi adaptado em Córdoba (Argentina), dividindo as dimensões da regulação de metas de acordo com as estratégias empregadas, sejam elas por aproximação ou evitação. Esta pesquisa propõe analisar novas evidências de validade e confiabilidade do QEAM. Participaram 412 estudantes universitários de Buenos Aires (Argentina). A análise da estrutura interna do instrumento, por meio da análise fatorial confirmatória (AFC), e da análise exploratória de equações estruturais (ESEM) verificou o melhor ajuste para o modelo de oito fatores. Em seguida, uma análise de invariância fatorial entre amostras de estudantes de Buenos Aires e Córdoba verificou a equivalência métrica do QEAM. A consistência interna das dimensões foi adequada (> 0,70). Em seguida, o teste de validade concorrente revelou correlações positivas e significativas com as abordagens de aprendizagem e correlações negativas com a procrastinação acadêmica. As normas estatísticas também foram estimadas. Este trabalho fornece novas evidências sobre as propriedades psicométricas do QEAM e escalas que permitem seu uso e interpretação no campo de aplicação.

Tall salt marshes play a crucial role in the long-term geomorphic evolution of the Jiuduansha wetland, Yangtze estuary, China Ma, Hao; Wang, Lihua; Pratolongo, Paula Daniela; Wu, Guoxiang; Shi, Benwei Salt marshes play a pivotal role in shaping coastal wetlands by influencing hydrodynamics and sediment transport, a topic that has garnered increasing attention in recent studies. However, the specific roles of different vegetation types in driving geomorphic evolution remain unclear. This study aims to assess the impact of varying salt marsh vegetation on the long-term geomorphic evolution of coastal wetlands. Using 1449 satellite images spanning 39 years (1984–2023) from the Google Earth Engine data archive, we investigated how different salt marsh types influences geomorphic changes on Jiuduansha Island, the largest uninhabited island in the Yangtze Estuary, China. Our analysis focused on the long-term salt marsh expansion and geomorphic evolution of Jiuduansha. The results revealed that the total area of Jiuduansha, as well as the extent of tall salt marshes, has increased significantly over the past decade. Notably, tall salt marshes exert a profound influence on geomorphic evolution. Specifically, in the accretionary sections of Jiuduansha Island, the natural expansion of tall salt marshes (Spartina alterniflora and Phragmites australis, with mean heights of 1.8 m and 2.5 m, respectively) drives seaward progradation. Conversely, in erosional sections, these tall salt marshes play a crucial role in mitigating further shoreline erosion. This study underscores the significant role of tall salt marshes in the long-term geomorphic evolution of coastal wetlands, offering valuable insights into the dynamics of wetland ecosystems and their resilience to environmental changes.

Modeling and solving an integrated periodic vehicle routing and capacitated facility location problem in the context of solid waste collection González, Begoña; Rossit, Diego Gabriel; Frutos, Mariano; Méndez, Máximo Few activities are as crucial in urban environments as waste management. Mismanagement of waste can cause significant economic, social, and environmental damage. However, waste management is often a complex system to manage and therefore where computational decision-support tools can play a pivotal role in assisting managers to make faster and better decisions. In this sense, this article proposes, on the one hand, a unified optimization model to address two common waste management system optimization problem: the determination of the capacity of waste bins in the collection network and the design and scheduling of collection routes. The integration of these two problems is not usual in the literature since each of them separately is already a major computational challenge. Two improved exact formulations based on mathematical programming and two metaheuristic methods are provided to solve this proposed unified optimization model. It should be noted that the metaheuristics consider a mixed chromosome representation of the solutions combining binary and integer alleles, in order to solve realistic instances of this complex problem. Different parameters of the metaheuristics considered – a Genetic Algorithm and a Simulated Annealing algorithm – have been tested to study which combination of them obtained better results in execution times on the order of that of the exact solvers. The achieved results show that the proposed metaheuristic methods perform efficient on large instances, where exact formulations are not applicable, and offer feasible, high-quality solutions in reasonable calculation times.

Spectrally distinguishing symmetric spaces I Lauret, Emilio Agustin; Rodríguez, Juan Sebastián We prove that the irreducible symmetric space of complex structures on (resp. quaternionic structures on ) is spectrally unique within a 2-parameter (resp. 3-parameter) family of homogeneous metrics on the underlying differentiable manifold. Such families are strong candidates to contain all homogeneous metrics admitted on the corresponding manifolds. The main tool in the proof is an explicit expression for the smallest positive eigenvalue of the Laplace-Beltrami operator associated to each homogeneous metric involved. As a second consequence of this expression, we prove that any non-symmetric Einstein metric in the homogeneous families mentioned above is -unstable.

Bridging Sectors and Disciplines to Gain a Critical Understanding of the Eco-Social Determinants of Health Inequities: The ESDHI-EU Conference Morrison, Joana; Tumas, Natalia; Moreno Mattar, Ornella; Gutiérrez Zamora Navarro, Mariana; Pericas, Juan M.; Martínez Herrera, Eliana; Cash-Gibson, Lucinda; Caroz Armayones, Josep Maria; Ruisoto, Pablo; Zografos, Christos; Rodríguez Labajos, Beatriz; Vergés Vega, Paula; Londoño, Ángela; Bautista, Marya; Karaguesian, Claire; Nuñez, Daniel; Muntané, Ferràn; Jiménez, Humberto; Vivas, Laila; Velázquez, Linda; Hsu, Po-Yen; Muntaner, Carles; Benach, Joan; Ribbons, Aeve The current eco-social crisis is driven by an unsustainable socioeconomic model based on continued economic growth that exceeds planetary limits. Groups experiencing disadvantages are being disproportionately affected, further deepening global, regional, and local health inequities. Understanding the simultaneous ecological and social crises through a comprehensiveapproach across disciplines and sectors—including citizen participation—is essential for driving transformative change and paradigm shifts. Achieving genuine ecological sustainability, social justice, and health equity is critical for transitioning towards a new social-ecological paradigm in research and policy. This requires transformative research and policymaking in key areas—eco-social crisis; democracy, social inclusion and participation; geopolitics; and equitable, sustainable cities—all of which represent pressing challenges within this global crisis, and serve as thematic axes for the European conference Rethinking the Eco-Social Determinants of Health Inequities through the Transdisciplinary and Intersectoral Lens (ESDHI-EU), which will be held inBarcelona, Spain, on May 22–23, 2025, and will explore the root causes of health inequities from a transdisciplinary, intersectoral, and transnational perspective.

Ajuste libertario, crisis y estabilización: Efectos sobre la dinámica de la pobreza y la desigualdad social Salvia, Hector Agustin; Vera, Julieta; Bonfiglio, Juan José; Giannecchini, Alejo Este artículo analiza el empobrecimiento de la sociedad argentina entre 2022 y 2024, con énfasis en los efectos sociales de las políticas de ajuste implementadas por el gobierno libertario de Javier Milei. A partir de la Encuesta de la Deuda Social Argentina (EDSA-ODSA-UCA), se examina la evolución de la pobreza combinando la medición tradicional por ingresos con indicadores directos de privación económica. El estudio relativiza la medición oficial de la pobreza, ya que no considera los cambios en la estructura del gasto de los hogares. Si bien se analiza la evolución de las tasas de indigencia y pobreza por ingresos, el estudio amplía el enfoque mediante la inclusión de otros indicadores directos de necesidades básicas de los hogares, como la seguridad alimentaria y el acceso a la salud. Además, incorpora un análisis longitudinal sobre la probabilidad de entrar, salir o permanecer en la pobreza durante el período 2022-2024. Los resultados evidencian que el ajuste ha profundizado las privaciones económicas y la desigualdad, afectando especialmente a los sectores más vulnerables, lo que subraya la necesidad de mediciones más integrales.; This article analyzes the impoverishment of Argentine society between 2022 and 2024, focusing on the social effects of the adjustment policies implemented by the libertarian government of Javier Milei. Using data from the Encuesta de la Deuda Social Argentina (EDSA-ODSA-UCA), it examines the evolution of poverty by combining traditional incomebased measurement with direct indicators of economic deprivation. The study challenges the official poverty measurement, as it does not account for changes in household expenditure structures. While the analysis includes the evolution of indigence and incomebased poverty rates, it expands the scope by incorporating additional direct indicators of basic household needs, such as food security and access to healthcare. Furthermore, it integrates a longitudinal analysis of the likelihood of entering, exiting, or remaining in poverty during the 2022-2024 period. The results show that the adjustment policies have deepened economic deprivation and inequality, disproportionately affecting the most vulnerable sectors. These findings underscore the need for more comprehensive poverty measurement approaches.

Assessment of encapsulation of digestive enzymes recovered from South Atlantic fish wastes for potential biotechnological applications Friedman, Ivana Soledad; Fernandez Gimenez, Analia Veronica; Alarcón López, Francisco Javier; Vizcaíno, Antonio Jesús Fish viscera represent an abundant and cost-effective source of digestive enzymes, particularly proteinases, which can be readily extracted and employed as bioactive components in various industrial processes to obtain value-added products. However, proteinases are sensitive to environmental factors. A successful method for maintaining their enzymatic activity is encapsulation. The aim of this study was to evaluate the encapsulation efficiency of alkaline and acid proteinases derived from wastes of the commercial fish species Merluccius hubbsi and Percophis brasiliensis from the Southwest Atlantic Ocean, and to determine the stability of their enzymatic activity under different storage conditions (room temperature and 4ºC). In addition, the effectiveness of the encapsulated proteinases using an in vitro digestion simulation assay was assessed. The results indicated that P. brasiliensis proteinases immobilized in fresh microcapsules and stored at 4°C remained stable for 60 days. Alkaline proteinases stored in freeze-dried microcapsules from both species, and fresh microcapsules from P. brasiliensis, retained their activity at both storage temperatures for 60 days. Aspartic proteinases from both species, encapsulated in freeze-dried capsules and stored at 4°C, maintained catalytic activity. In vitro enzymatic hydrolysis assays confirmed that casein is hydrolyzed after 60 min by both the encapsulated and free enzymes. In turn, the amount of free amino acids released from casein leveled off after 180 min of in vitro assay. These results evidenced that encapsulation using a combination of alginate and chitosan is a promising tool for different biotechnological applications of these fish enzymes such as elaboration of commercial detergent additives and aquafeeds.

Obvious manipulations in matching with and without contracts Arribillaga, Roberto Pablo; Pepa Risma, Eliana Beatriz This paper explores many-to-one matching models, both with and without contracts, where doctors’ preferences are private and hospitals’ preferences are public and substitutable. It is known that any stable-dominating mechanism --which is either stable or individually rational and Paretodominates (from the doctors’ perspective) a stable mechanism–, is susceptible to manipulation by doctors. Our study focuses on obvious manipulations and identifies stable-dominating mechanisms that prevent them. Without contracts, we show that any stable-dominating mechanism is not obviously manipulable. However, with contracts, none of these results hold. While we demonstrate that the Doctor-Proposing Deferred Acceptance (DA) Mechanism remains not obviously manipulable, we show that the Hospital-Proposing DA Mechanism and any efficient mechanism that Pareto-dominates the Doctor-Proposing DA Mechanism become (very) obviously manipulable, in the model with contracts.

Fipronil tissue residues and withdrawal period feasibility in laying hens after extra‐label use Cantón, Lucila; Berkovic, Andrea Mariela; Ceballos, Laura; Cantón, Candela; Lanusse, Carlos Edmundo; Alvarez, Luis Ignacio; Moreno Torrejon, Laura Fipronil, a broad-spectrum insecticide, is often used off-label in laying hens to control red mites. This study investigatedfipronil residue levels in hen tissues after simulating common extra-label administrations: in-feed (1 mg kg−1 twice) and transdermal (1 mg kg−1 once). Fipronil residues were quantified by HPLC-MS/MS. Both administrations resulted in quantifiableresidues in edible tissues (muscle, liver, kidney, skin, fat) and feathers for up to 60 days. Fipronil-sulfone, the primary metabolite, was the dominant residue in tissues. Fat accumulated the highest concentrations. In-feed administration led to higheroverall residues in edible tissues, while transdermal application resulted in higher concentrations in feathers. Calculated withdrawal periods, based on established MRLs, ranged from 36 days (muscle, transdermal) to 131 days (fat, transdermal). Theselong withdrawal periods render both administration routes impractical for poultry production. The study highlights the riskof fipronil residues in poultry products and suggests feather/fecal sampling for monitoring illicit use.

Concentración de compuestos organobromados en Delphinus delphis y Lagenodelphis hosei Concentración de compuestos organobromados expresados en ng.g−1 de peso húmedo, determinados en tejido adiposo de Delphinus delphis y Lagenodelphis hosei

Isospectral CR Manifolds with Respect to the Kohn Laplacian Gutierrez, Gerson; Lauret, Emilio Agustin; Rossetti, Juan Pablo We prove that the spectrum of the Kohn Laplacian does not determine the equivalence classes of CR manifolds. We construct pairs of odd-dimensional elliptic manifolds that are not equivalent as CR manifolds but whose Kohn Laplacians have the same spectrum. These manifolds are endowed with the CR structures inherited from the canonical CR structure on the sphere of the same dimension.We provide three different constructions among lens spaces and an additional one among elliptic manifolds with non-cyclic fundamental groups.

Validating a Target‐Enrichment Design for Capturing Uniparental Haplotypes in Ancient Domesticated Animals More, Kuldeep D.; Lebrasseur, Ophélie; Garrido, Jaime Lira; Seguin Orlando, Andaine; Discamps, Emmanuel; Estrada, Oscar; Tonasso Calvière, Laure; Chauvey, Loreleï; Tressières, Gaëtan; Schiavinato, Stéphanie; Gibert, Morgane; Padula, Horacio; Chiavazza, Horacio Daniel; Fernández, Pablo Marcelo; Guardia, Nicolás Maximiliano; Borges, Caroline; Bertani, Stéphane; Contreras Mancilla, Juan; Allccarima Crisóstomo, Diana; Fhon, Miguel; Barrey, Eric; Charliquart, Léa; Robbe, Emilie; de Noblet, Thibault; Zhumatayev, Rinat; Dalen, Love; Bradley, Daniel G.; Frantz, Laurent; Larson, Greger; Orlando, Ludovic In the last three decades, DNA sequencing of ancient animal osteological assemblages has become an important tool complementing standard archaeozoological approaches to reconstruct the history of animal domestication. However, osteological assemblages of key archaeological contexts are not always available or do not necessarily preserve enough ancient DNA for a cost-effective genetic analysis. Here, we develop an in-solution target-enrichment approach, based on 80-mer species-specific RNA probes (ranging from 306 to 1686 per species) to characterise (in single experiments) the mitochondrial genetic variation from eight domesticated animal species of major economic interest: cattle, chickens, dogs, donkeys, goats, horses, pigs and sheep. We also illustrate how our design can be adapted to enrich DNA library content and map the Y-chromosomal diversity within Equus caballus. By applying our target-enrichment assay to an extensive panel of ancient osteological remains, farm soil, and cave sediments spanning the last 43 kyrs, we demonstrate that minimal sequencing efforts are necessary to exhaust the DNA library complexity and to characterise mitogenomes to an average depth-of-coverage of 19.4 to 2003.7-fold. Our assay further retrieved horse mitogenome and Y-chromosome data from Late Pleistocene coprolites, as well as bona fide mitochondrial sequences from species that were not part of the probe design, such as bison and cave hyena. Our methodology will prove especially useful to minimise costs related to the genetic analyses of maternal and paternal lineages of a wide range of domesticated and wild animal species, and for mapping their diversity changes over space and time, including from environmental samples.

El futuro del pasado: los estudios de género como archivo; The Future of the Past: Gender Studies as Archive Villagarcía Pieretti, Martín Ricardo El presente artículo se propone mostrar cómo los estudios de género se invisten con las características de un archivo, muchas veces arrojados al futuro y a destiempo de su momento de intervención en el debate público, para encontrar allí un horizonte de recepción que desdibuja los límites de lo contemporáneo. Para ello primero se realiza un rastreo por diferentes teorías acerca del archivo, con especial hincapié en los trabajos de Michel Foucault y Jacques Derrida, y el posterior "giro archivístico" de las ciencias sociales y humanas y sus derivas "anarchivísticas". A partir de esta nueva configuración acerca de "la ley de lo que puede ser dicho", en palabras de Foucault, se enlazan las teorías del archivo con los estudios de género y su capacidad de problematizar afirmaciones históricamente incuestionables. Para terminar, se advierte el "efecto de contemporaneidad", propuesto por Giorgio Agamben, que producen los estudios de género en tanto archivos al encontrar una coyuntura histórica donde produzcan sentido.; This article aims to show how gender studies are invested with the characteristics of an archive, often thrown into the future and at the wrong time of their moment of intervention in the public debate, only to find there a horizon of reception that blurs the limits of what contemporary means. To do this, first a search is carried out through different theories about the archive, with special emphasis on the works of Foucault and Derrida, and the subsequent “archival turn” of the social and human sciences and its “anarchivistic” drifts. Starting from this new configuration about “the law of what can be said,” in Foucault‘s words, archive theories are linked to gender studies and their ability to problematize historically unquestionable statements. To conclude, the “effect of contemporaneity”, proposed by Giorgio Agamben, produced by gender studies as archives is noted when finding a historical situation where they produce meaning.

Ensuciar el cine y las buenas costumbres: Una lectura queer de Diapasón de Jorge Polaco en el marco de la recuperación democrática; Sujar o cinema e os bons costumes: uma leitura queer de Diapasón de Jorge Polaco no contexto da redemocratização; Defiling Cinema and Good Manners: A Queer Reading of Diapasón by Jorge Polaco in the Context of Democratic Recovery Rubino, Atilio Raúl Este artículo analiza el primer largometraje de Jorge Polaco, Diapasón (1986), desde una perspectiva queer y sexo-disidente, y en el marco del cine argentino de la postdictadura. Si bien no trata la homosexualidad como tema central, proponemos pensar que buscó horadar y ensuciar la heterosexualidad entendida como régimen político y sus instituciones más importantes como la familia y la moral. Asimismo, la búsqueda formal antirrealista (camp y barroca) y la tematización de la mugre de la ciudad y la violencia que implica su higienización nos permiten considerarla desde una perspectiva queer. La película exhibe, por lo tanto, desde lo temático y desde lo formal, la cisura que separa lo normal de lo anormal, y en su alusión al pasado dictatorial, el plan de exterminio como una maquinaria antropológica que no sólo limpia la suciedad de lo social sino también las impurezas de la sexualidad.; Este artigo analisa o primeiro longa-metragem de Jorge Polaco, Diapasón (1986), sob uma perspectiva queer e sexo-dissidente, inserindo-o no contexto do cinema argentino pós-ditadura. Embora não aborde a homossexualidade como tema central, propomos uma reflexão sobre como o filme buscou corroer e sujar a heterossexualidade entendida como regime político, bem como suas instituições centrais — a família e a moral. Da mesma forma, sua busca formal antirrealista (camp e barroca) e a tematização da sujeira urbana e da violência inerente a sua higienização permitem analisá-lo a partir de uma leitura queer. A película exibe, tanto no plano temático quanto no plano formal, a cisão que separa o normal do anormal. Por meio de sua alusão ao passado ditatorial, expõe o plano de extermínio como uma maquinaria antropológica que não apenas limpa a imundície social, mas também as impurezas da sexualidade.; This paper analyses Jorge Polaco's first feature film, Diapasón (1986), from a queer and sex-dissident approach in the context of post- dictatorship Argentine cinema. Although homosexuality is not the central theme, we posit that the film undermines and contaminates heterosexuality–– understood as a political regime––along with its most important pillars, the family and morality. The (camp and baroque) anti-realist aesthetics, together with the topoi of the city's filth and the violence required to clean it, allow a queer approach. Diapasón underscores the rupture of normalcy thematically and aesthetically. The allusion to the dictatorial past exposes the extermination plan as an anthropological machine that cleanses the social body’s filth and the impurities of sexuality.

El reparto de alimentos ¿Un derecho humano, beneficencia o marxismo? Representaciones sobre el Programa Alimentario Nacional (1983-1989); Food distribution: Human right, charity or marxism? Representations on the National Food Programme (1983-1989) Osuna, María Florencia Este artículo analiza las representaciones construidas en torno al Programa Alimentario Nacional (PAN) (1983-1989), cuyo objetivo fue disminuir el hambre y la desnutrición en la posdictadura. Da cuenta de las posiciones de diferentes actores políticos y sociales sobre el PAN: los funcionarios del gobierno, los partidos políticos, los principales medios de comunicación y la inteligencia policial de la Provincia de Buenos Aires. Las representaciones de estos actores permiten observar que la intervención social del estado en la posdictadura se percibió de diferentes maneras: como beneficencia, clientelismo político, corrupción y como una amenaza al orden social. Aun así, el gobierno y los expertos vinculados a estas políticas intentaron comenzar a instalar el concepto de que las prestaciones sociales eran un derecho humano que había sido vulnerado por la dictadura.; This article analyses the representations constructed around the National Food Programme (PAN) (1983-1989), whose aim was to reduce hunger and malnutrition in the post-dictatorship period. It describes the positions of different political and social actors on the PAN: government officials, political parties, the main media and police intelligence in the Province of Buenos Aires. The representations of these actors show that the state's social intervention in the post-dictatorship period was perceived in different ways: as charity, political clientelism, corruption and as a threat to social order. Even so, the government and experts linked to these policies tried to begin to install the concept that social benefits were a human right that had been violated by the dictatorship.

Vigencia de la Lucha de Clases Galafassi, Guido Pascual En esta sociedad en donde el occidente se encuentra en franca decadencia, así como sus ideas fuerzas y valores, el entender a la sociedad como un espacio en donde prima la lucha de clases aparece como algo perimido, incluso para la mayor parte de la auto-percibida “izquierda”. Para las derechas conservadoras siempre fue la categoría a anular sin tapujos, el liberalismo socialdemócrata y populista siempre lo supo integrar más hábilmente a partir de su principio de alianza de clases. Y para la izquierda, es decir movimiento y partidos de base marxista, la lucha de clases fue siempre la idea fuerza fundamental por aquello de Marx de que el motor de la historia lo constituye precisamente la lucha de clases. Lo fue, hasta las últimas décadas en que el Identitarismo tomó su lugar. Este escrito entonces intenta volver a poner a la lucha de clases en el centro de la batalla anticapitalista, lucha de clases que en el capitalismo se asienta centralmente en la contradicción capital-trabajo, más allá de estar necesariamente secundada por contradicciones complementarias que complejizan notoriamente la realidad, lo que obliga siempre a agudizar el análisis.

Climate change scenarios and the increasing severity of thermal extremes in the pampas region Brendel, Andrea Soledad; Ferrelli, Federico; Piccolo, Maria Cintia This research aimed to analyze the Spatial and Temporal trends and variations of extreme thermal events in the Pampas region (Argentina) over three periods: the present (2009–2023), the near future (2024–2038), and the Far future (2085–2099) under two greenhouse gas concentration scenarios, RCP 4.5 and RCP 8. Across these periods, 14 extreme thermal indices were calculated using maximum and minimum temperature series recorded in situ by 48 meteorological stations. For future projections, we employed two validated climate models: the CCSM4 model (validation index: 0.91) for the humid region and the CNRM-CM5 model (validation index: 0.91) for the central region, selected based on their high performance in representing regional thermal conditions. Results revealed a significant warming trend, with regional maximum temperature increasing by 1.1 °C during 2009–2023, and projections of up to 1.4 °C increase in the Far future under RCP 8.5. A notable Spatial heterogeneity was observed, with Western and central sectors of the Pampas showing more pronounced warming patterns than Eastern coastal areas. Extreme indicators showed pronounced changes: absolute maximum temperature (TXx) increased by 2.5 °C in the present period, with projections of up to 4.9 °C increase by 2085–2099 under RCP 8.5. Warm days (TX90p) increased by 5 days/15 years in the present, with projections of 6.7 days/15 years in the Far future. Concurrently, cold events decreased significantly, with cool days (TX10p) declining by 6 days/15 years in the present and projected to decrease by 7.1 days/15 years in the Far future. This thermal intensification will adversely affect agricultural production, economic development, infrastructure, biodiversity, and public health, heightening the vulnerability of the region’s socio-ecosystems. These findings are critical for developing Spatial management plans and designing climate adaptation and mitigation measures at local and regional scales.

Unraveling Tumor Heterogeneity: Quantitative Insights from Single-cell RNA Sequencing Analysis in Breast Cancer Subtypes Senra, Daniela; Guisoni, Nara Cristina; Diambra, Luis Anibal Background and objectives: Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels. This study introduced a novel framework for quantifying cancer cell heterogeneity using single-cell RNA sequencing data. The framework comprised several scores aimed at uncovering the complexities of key cancer traits, such as metastasis, tumor progression, and recurrence. Methods: This study leveraged publicly available single-cell transcriptomic data from three human breast cancer subtypes: estrogen receptor-positive, human epidermal growth factor receptor 2-positive, and triple-negative. We employed a quantitative approach, analyzing copy number alterations (CNAs), entropy, transcriptomic heterogeneity, and diverse protein-protein interaction networks (PPINs) to explore critical concepts in cancer biology. Results: We found that entropy and PPIN activity related to the cell cycle could distinguish cell clusters with elevated mitotic activity, particularly in aggressive breast cancer subtypes. Additionally, CNA distributions varied across cancer subtypes. We also identified positive correlations between the CNA score, entropy, and the activities of PPINs associated with the cell cycle, as well as those linked to basal and mesenchymal cell lines. Conclusions: This study addresses a gap in the current understanding of breast cancer heterogeneity by presenting a novel quantitative approach that offers deeper insights into tumor biology, surpassing traditional marker-based methods.