Ciencia y Tecnología

ANR Empresa Joven FONSOFT 2015 C2

ANPCyT -

El Fondo Fiduciario de Promoción de la Industria del Software (FONSOFT) anuncia los resultados del proceso de evaluación para la convocatoria ANR Empresa Joven FONSOFT 2015 C2 mediante Resolución de Directorio N°516 y 521/16.

ANR FONSOFT Capacitación - Actualización de formularios y bases

ANPCyT -

La Agencia Nacional de Promoción Científica y Tecnológica, a través del Fondo Fiduciario de Promoción de la Industria del Software (FONSOFT), llama a la presentación de Proyectos de formación continua del sector de TICs, para su financiamiento parcial a través de Aportes No Reembolsables, en los términos y condiciones definidos en el presente documento, destinados a Instituciones Públicas con aporte fiscal directo, o a Instituciones Privadas sin fines de lucro.

Criticality of environmental information obtainable by dynamically controlled quantum probes

CONICET Digital -

Criticality of environmental information obtainable by dynamically controlled quantum probes Zwick, Analía Elizabeth; Alvarez, Gonzalo Agustin; Kurizki, Gershon A universal approach to decoherence control combined with quantum estimation theory reveals a critical behavior, akin to a phase transition, of the information obtainable by a qubit probe concerning the memory time of environmental fluctuations of generalized Ornstein-Uhlenbeck processes. The criticality is intrinsic to the environmental fluctuations but emerges only when the probe is subject to suitable dynamical control aimed at inferring the memory time. A sharp transition is anticipated between two dynamical phases characterized by either a short or long memory time compared to the probing time. This phase transition of the environmental information is a fundamental feature that characterizes open quantum-system dynamics and is important for attaining the highest estimation precision of the environment memory time under experimental limitations.

Informes Técnicos - Actualización

ANPCyT -

Se recuerda a los responsables de los proyectos adjudicados y que actualmente se encuentran en ejecución, que es requisito presentar un informe técnico por cada año transcurrido desde la fecha de inicio del proyecto.

Apertura de ANR TEC 2016 C2

ANPCyT -

La Agencia Nacional de Promoción Científica y Tecnológica, a través del Fondo Tecnológico Argentino (FONTAR), convoca a la presentación de Proyectos de Innovación Tecnológica para la adjudicación de Aportes No Reembolsables (ANR TEC) destinados al financiamiento de proyectos de mejora de la competitividad mediante la incorporación de tecnología, presentados por empresas PYMES en el marco del Préstamo BIRF 7599/AR.

Physical and mechanical properties of raspberries subjected to osmotic dehydration and further dehydration by air- and freeze-drying

CONICET Digital -

Physical and mechanical properties of raspberries subjected to osmotic dehydration and further dehydration by air- and freeze-drying Sette, Paula Andrea; Salvatori, Daniela Marisol; Schebor, Carolina Claudia The aim of this study was to analyze the effect of the application of dry and wet sucrose infusions, as pretreatments previous to air- and freeze-drying, on mechanical and physical properties of raspberries: water sorption, glass transition temperature (Tg), molecular mobility, texture and rehydration properties. Different dry and wet sugar infusions were prepared using combinations of additives: sodium bisulphite, citric acid, sodium bisulphite and citric acid, and no additives. These specific pretreatments are often used to obtain better sensorial characteristics of fruits upon further drying. After the dehydration step (air- or freeze-drying), all the samples were in the supercooled state. Pretreated samples presented lower Tg values and lower spin–spin relaxation times than control samples. Regarding texture, pretreated samples showed lower firmness than control samples. Also, freeze-dried pretreated samples showed higher firmness and lower deformability than air-dried pretreated ones. When considering the hygroscopicity, freeze-dried samples were more hygroscopic than air-dried ones. The fresh-like dried raspberries obtained could be directly consumed as snacks or incorporated in a composite food, such as a cereal mix. In this latter case, pretreated fruits would be more suitable, since their rehydration capacity at short times was relatively low.

Gallbladder cancer: South American experience

CONICET Digital -

Gallbladder cancer: South American experience Arroyo, Gerardo F.; Gentile, Alberto; Parada, Luis Antonio Large differences in terms of incidence and mortality due to gallbladder cancer (GBC) have been reported worldwide. Moreover, it seems that GBC has unique characteristics in South America. We surveyed the literature looking for information about the epidemiology, basic and translational research, and clinical trials performed in South America in order to critically analyze the magnitude of this health problem in the region. Compared to other geographic areas, age-standardized mortality rates (ASMR) for GBC in women are very high, particularly in many western areas of South America. Genetic, as well as dietary and environmental factors likely contribute to the pathogenesis of this disease in the area. Compared to other regions the profile of abnormalities of key genes such as KRAS and TP53 in GBC seems to slightly differ in South America, while the clinical behavior appears to be similar with a median overall survival (OS) of 6.5 to 8 months in advanced GBC. In contrast to Europe and USA, prophylactic cholecystectomy is a common practice in western areas of South America. GBC particularly affects women in South America, and represents a significant public health problem. It appears to have peculiarities that pose an urgent need for additional research aimed to discover risk factors, molecular events associated with its development and new treatment options for this lethal disease.

Una técnica robusta para modelar el rompimiento de la estela vorticosa en generadores eólicos de gran potencia y eje horizontal

CONICET Digital -

Una técnica robusta para modelar el rompimiento de la estela vorticosa en generadores eólicos de gran potencia y eje horizontal Gomez, Cynthia Noelia; Preidikman, Sergio; Lopez Mejia, Omar D.; Roccia, Bruno Antonio Con el fin de aumentar el conocimiento del comportamiento aerodinámico de turbinas eólicas de eje horizontal y de gran potencia y lograr así un correcto diseño de las mismas, los estudios aerodinámicos, aeroelásticos y aeroservoelásticos de estos sistemas de generación de energías limpias han recobrado interés durante los últimos años. En este trabajo se presenta el desarrollo e implementación computacional de un nuevo método de simulación del fenómeno de ruptura de las estelas vorticosas generadas por las palas al impactar la torre portante; dicha componente influye de manera directa en el comportamiento de la potencia mecánica de la turbina. La nueva técnica numérica se implementó en un código computacional ya existente, basado en una versión modificada del método de red de vórtices no lineal y no estacionario. Con el objetivo de poner en evidencia la eficiencia y robustez del nuevo método de ruptura, se comparan los resultados numéricos con un esquema desarrollado con anterioridad. Además, se analiza cualitativamente la forma de la ruptura al variar el número de elementos aerodinámicos utilizados para discretizar las palas y la torre. Finalmente, para analizar cuantitativamente la influencia de la discretización aerodinámica de la pala en el modelo de ruptura, se calculan los tiempos dimensionales de comienzo y finalización de la primera ruptura de estela y se extraen conclusiones.; With the objective of increasing knowledge regarding the behavior of Large-Scale Horizontal-Axis Wind Turbines (LSHAWTs) and provide a correct design for them, during the last years, the aerodynamic, aeroelastic and aeroservoelastic studies have become of interest. In this paper, a new numerical method to simulate the wake rupture against the supporting tower is developed. This simulation scheme is implemented into an existing computational code and represents an improvement in the process of detecting wake vortex segments going through the body of the tower. The numerical tool is based on a modified version of the well-known unsteady vortex-lattice method. In order to validate the efficiency and robustness of the proposed wake rupture method, current numerical results are compared against results obtained using a numerical scheme developed previously. Moreover, a qualitative analysis of shape variations of the wake rupture as a function of the number of aerodynamic elements on both the blades and the tower is carried out. Finally, to analyze quantitatively the influence of aerodynamic discretization of the blade on the wake rupture model, the starting- and ending-time of the first rupture are computed. Conclusions are drawn.

Genomic imbalances and microRNA transcriptional profiles in patients with mycosis fungoides

CONICET Digital -

Genomic imbalances and microRNA transcriptional profiles in patients with mycosis fungoides Garaicoa, Fuad Huaman; Roisman, Alejandro; Arias, Mariana; Trila, Carla; Fridmanis, Miguel; Abeldaño, Alejandra; Vanzulli, Silvia; Narbaitz, Marina; Slavutsky, Irma Rosa Mycosis fungoides is the most common type of primary cutaneous T cell lymphoma. We have evaluated CDKN2A losses and MYC gains/amplifications by FISH analysis, as well as expression of miR-155 and members of the oncogenic cluster miR-17-92 (miR17, miR18a, miR19b, and miR92a) in MF patients with advanced disease. Formalin-fixed paraffin-embedded skin biopsies from 36 patients at diagnosis, 16 with tumoral MF (T-MF), 13 in histological transformation to a large T cell lymphoma (TR-MF), and 7 cases with folliculotropic variant (F-MF), were studied. Twenty cases showed genomic alterations (GAs): 8 (40 %) had CDKN2A deletion, 7 (35 %) showed MYC gain, and 5 (25 %) exhibited both alterations. GAs were more frequently observed in F-MF (p = 0.004) and TR-MF (p = 0.0001) than T-MF. GAs were significantly higher in cases presenting lesions in head, neck, and lower extremities compared to those observed in trunk and upper extremities (p = 0.03), when ≥25 % neoplastic cells were CD30 positive (p = 0.016) as well as in cases with higher Ki-67 proliferation index (p = 0.003). Patients with GAs showed bad response to treatment (p = 0.02) and short survival (p = 0.04). Furthermore, MF patients showed higher miRNA expression compared to controls (p ≤ 0.0223). T-MF showed higher miR17 and miR-18a expression compared to F-MF and TR-MF (p ≤ 0.0387) while miR19b, miR92a, and miR-155 showed increased levels in F-MF and TR-MF with respect to T-MF (p ≤ 0.0360). Increased expression of miR17 and miR19b in GA group compared to cases without alterations (p ≥ 0.0307) was also detected. Our results add new information about genomic imbalances in MF patients, particularly in F-MF, and extend the present view of miRNA deregulation in this disease.

Páginas

Suscribirse a Facultad de Ciencias Químicas de la Universidad Nacional de Córdoba agregador - Ciencia y Tecnología