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Perceptions and knowledge of local people toward an endangered armadillo from the Buenos Aires coast, Argentina

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Perceptions and knowledge of local people toward an endangered armadillo from the Buenos Aires coast, Argentina Pagnutti, Norali; Zufiaurre, Emmanuel; Ezquiaga, María Cecilia; Abba, Agustin Manuel In a large area used for livestock production in the north east of the Pampas region of Buenos Aires, central Argentina, there is a subpopulation of endangered armadillo species (Chaetophractus vellerosus) which is threatened by mining activities. Knowledge and perception of local communities living in the range of the endangered species were evaluated using an anonymous online questionnaire. A total of 618 questionnaires were filled out, with the majority of respondent (82%) not being aware of the existence of this species. The study documented the lack of knowledge and the need to develop strategies to increase local communities’ awareness toward this species.

Extrapolation of Type Ia Supernova Spectra into the Near-infrared Using Principal Component Analysis

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Extrapolation of Type Ia Supernova Spectra into the Near-infrared Using Principal Component Analysis Burrow, Anthony; Baron, E.; Burns, Christopher R.; Hsiao, Eric; Lu, Jing; Ashall, Chris; Brown, Peter J.; DerKacy, James M.; Folatelli, Gaston; Galbany, Lluís; Hoeflich, Peter; Krisciunas, Kevin; Morrell, Nidia Irene; Phillips, M. M.; Shappee, Benjamin J.; Stritzinger, Maximilian; Suntzeff, Nicholas B. We present a method of extrapolating the spectroscopic behavior of Type Ia supernovae (SNe Ia) in the near-infrared (NIR) wavelength regime up to 2.30 μm using optical spectroscopy. Such a process is useful for accurately estimating K-corrections and other photometric quantities of SNe Ia in the NIR. A principal component analysis is performed on data consisting of Carnegie Supernova Project I & II optical and NIR FIRE spectra to produce models capable of making these extrapolations. This method differs from previous spectral template methods by not parameterizing models strictly by photometric light-curve properties of SNe Ia, allowing for more flexibility of the resulting extrapolated NIR flux. A difference of around ‑3.1% to ‑2.7% in the total integrated NIR flux between these extrapolations and the observations is seen here for most test cases including Branch core-normal and shallow-silicon subtypes. However, larger deviations from the observation are found for other tests, likely due to the limited high-velocity and broad-line SNe Ia in the training sample. Maximum-light principal components are shown to allow for spectroscopic predictions of the color-stretch light-curve parameter, s BV, within approximately ±0.1 units of the value measured with photometry. We also show these results compare well with NIR templates, although in most cases the templates are marginally more fitting to observations, illustrating a need for more concurrent optical+NIR spectroscopic observations to truly understand the diversity of SNe Ia in the NIR.

Binary origin of blue straggler stars in Galactic star clusters

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Binary origin of blue straggler stars in Galactic star clusters Rain, M. J.; Pera, M. S.; Perren, Gabriel Ignacio; Benvenuto, Omar Gustavo; Panei, Jorge Alejandro; de Vito, María Alejandra; Carraro, Giovanni; Villanova, S. Building on the recent release of a new Gaia-based blue straggler star catalog in Galactic open star clusters (OCs), we explored theproperties of these stars in a cluster sample spanning a wide range in fundamental parameters. We employed Gaia EDR3 to assessthe membership of any individual blue or yellow straggler to their parent cluster. We then made use of the ASteCA code to estimatethe fundamental parameters of the selected clusters, in particular, the binary fraction. With all this at hand, we critically revisitedthe relation of the blue straggler population and the latter. For the first time, we found a correlation between the number of bluestragglers and the host cluster binary fraction and binaries. This supports the hypothesis that binary evolution is the most viablescenario of straggler formation in Galactic star clusters. The distribution of blue stragglers in the Gaia color-magnitude diagram wasthen compared with a suite of composite evolutionary sequences derived from binary evolutionary models that were run by exploringa range of binary parameters: age, mass ratio, period, and so forth. The excellent comparison between the bulk distribution of bluestragglers and the composite evolutionary sequences loci further supports the binary origin of most stragglers in OCs and paves theway for a detailed study of individual blue stragglers

Valorization of a by-product of the yerba mate industry by assembling with cassava starch adhesive for packaging material production

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Valorization of a by-product of the yerba mate industry by assembling with cassava starch adhesive for packaging material production Monroy, Yuliana; Garcia, Maria Alejandra; Deladino, Lorena; Rivero, Sandra G. M. Yerba mate industrial processing produces tons of powder as a by-product, this yerba mate powder (YMP) is an excellent source of biomass to develop biodegradable materials. Cassava starch modified with 1,2,3,4-butane tetracarboxylic acid (BA) in the presence of sodium propionate as a catalyst is an eco-friendly option to obtain bioadhesives. This work aimed to develop sustainable laminates from starch-based adhesives and yerba mate powder and to study their physico-chemical, structural, and mechanical properties. Blends of bioadhesive and YMP were prepared (1:1, adhesive:YMP). Monolayer materials were obtained by thermo-compression and later assembled with adhesive to obtain bilayer laminates. Bioadhesive was able to bind the yerba mate by-product fibers, as evidenced by SEM microstructure analysis, the interactions of adhesive:substrate were elucidated by ATR-FTIR and supported by chemometrics analysis. The incorporation of the catalyst decreased the rugosity of materials and their mechanical performance was improved by the action of both acid concentration and catalyst presence, requiring higher energy for puncture. Thus, it was feasible to obtain mono and bi-layer laminates as an eco-compatible alternative for the design of sustainable tray-like materials based on the industrial by-product of yerba mate.

Atypical Spoilage Microorganisms inArgentinean Yogurts: Gas-ProducingMoldsandBacteria of the Genus Gluconobacter

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Atypical Spoilage Microorganisms inArgentinean Yogurts: Gas-ProducingMoldsandBacteria of the Genus Gluconobacter Capra, María Luján; Frisón, Laura Noemí; Chiericatti, Carolina Andrea Antonia; Binetti, Ana Griselda; Reinheimer, Jorge Alberto Microbiological spoilage of food leads to products unfit for consumption, and their discardingleadstosignificant economic losses for the food industry. During storage, fresh foods offer available niches for the survival andgrowth of undesirable microorganisms. In dairy products, data regarding spoilage and/or pathogenic bacteria is betterdocumented than those for molds and yeasts. Dairy products, due to their refrigerated storage and production fromheattreated milk, are less susceptible to mold contamination compared to fruits and vegetables. The dominant microbiotainfermented dairy products also contributes to acidifying the medium, further reducing the risk of spoilage. However, evencheeses and yogurts may be susceptible to mold contamination. Atypical cases of yogurt samples containingspoilagemicroorganisms not previously reported (molds producing gas and bacteria of the genus Gluconobacter) in Argentineanfermented milks are presented here. For yogurt, in particular, the "classic" altering organisms were always beingyeasts, and in other countries, molds belonging to the genus Aspergillus.

Fabrication of Highly Aligned Electrospun Collagen Nanofibers for Tissue Engineering

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Fabrication of Highly Aligned Electrospun Collagen Nanofibers for Tissue Engineering Macias, Jose A.; Pignatta, Evelyn A.; Bronstein, Noah Ansaldo; Cid, Mariana Paula; Salvatierra, Nancy Alicia; Comin, Romina Tissue engineering is aimed at tissue recovery, replacement or regeneration by designing materials inspired by biomimetics to recreate the natural environment for better cell and tissue growth. It is important to mimic the fibrillar structure of the extracellular matrix, essential for cellular organization, survival, and function. Collagen is a major constituent of many tissues and organs, as a result, collagen matrices are often used as a surrogate extracellular matrix for in vitro tissue engineering and in vivo tissue regeneration or repair. This work describes the fabrication of membranes formed by highly aligned collagen nanofibers by electrospinning for use in tissue engineering. Collagen was obtained by homogenization and enzymatic hydrolysis of bovine Achilles tendon, obtaining two samples: high purity collagen and the non-hydrolyzed fraction with 40% collagen. Both samples could be generated randomly oriented electrospun nanofibrous membranes when analyzed by confocal microscopy. The fabrication and incorporation of a rotating collector allowed us to obtain highly aligned nanofibrous membranes of the non-hydrolyzed fraction when we varied the speed of the collector.

Anuran consumption by burrowing owl (Athene cunicularia Strigiformes) in lower Chubut river valley, Patagonia, Argentina

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Anuran consumption by burrowing owl (Athene cunicularia Strigiformes) in lower Chubut river valley, Patagonia, Argentina Formoso, Anahí Elizabeth; Klaich, Javier M.; Udrizar Sauthier, Daniel Edgardo Burrowing Owl (Athene cunicularia Strigiformes) is widely distributed in American continent and mainly feeds on arthropods and small mammals, with anurans as an important prey seasonally. In Argentinean Patagonia, anurans presence was documented in one study that assessed the diet in Somuncurá plateau. Here we assessed the consumption of anurans by Burrowing Owls in the lower Chubut river valley (Chubut province, Argentina) and its relation with seasons. Two species of anurans are present: Rhinella arenarum (Bufonidae) and Pleurodema bufoninum (Leptodactylidae). Owl pellets were collected seasonally between 2018 and 2022 and dry-disintegrated in the laboratory. Minimum number of anuran individuals was calculated on the basis of ilea and the effect of years and seasons was evaluated with GLM. We analyzed 365 complete owl pellets and 64 prey remains. Anurans represented 44%F of consumed vertebrates and GLM analyses showed higher effect in spring and lower in summer. We identified the 24.2%F as R. arenarum and the 75.8%F undetermined species. We can infer that owls feed during day and night, given the activity pattern for anurans. Our results are similar for those found in spring in Argentina, but differ for other seasons, probably in relation to how anurans use the irrigation channels (spring-summer) and also activate when precipitation is more frequent (winter and spring). Considering that all prey remains and cranial bones belong to R. arenarum, and lacking direct evidence of P. bufoninum, we could suppose that unidentified ilea belong to the former. Nevertheless, this assumption cannot be confirmed until the presence or absent of P. bufoninum was recorded through sampling.

The spectral geometry of hyperbolic and spherical manifolds: analogies and open problems

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The spectral geometry of hyperbolic and spherical manifolds: analogies and open problems Lauret, Emilio Agustin; Linowitz, Benjamin The spectral geometry of negatively curved manifolds has received more attention than its positive curvature counterpart. In this paper we will survey a variety of spectral geometry results that are known to hold in the context of hyperbolic manifolds and discuss the extent to which analogous results hold in the setting of spherical manifolds. We conclude with a number of open problems.

Deleuze y el feminismo: Debates sobre el devenir-mujer

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Deleuze y el feminismo: Debates sobre el devenir-mujer; Deleuze and feminism: Debates on becoming-woman Antonelli Marangi, Marcelo Sebastián Este artículo investiga el concepto de devenir-mujer, y algunos de los debates que ha suscitado este concepto en la recepción de Deleuze en el campo de los estudios feminista y de género. Las interpretaciones han sido predominantemente negativas con base en críticas de diverso tipo: el significado del concepto no es claro ni definido; carece de eficacia política por su desconexión con las luchas concretas de las mujeres realmente existentes; oculta posiciones masculinas y etnocéntricas, andróginas o incluso patriarcales; conduce a un horizonte postfeminista que disuelve la identidad de la mujer e invisibiliza sus reclamos por reconocimiento; desconoce la importancia epistemológica y política de la diferencia sexual. La hipótesis propuesta en este escrito es que estas críticas pueden ser discutidas con argumentos fundados en una relectura rigurosa de este concepto en la obra deleuziana, que recupere distinciones clave (lo molar y lo molecular, la mayoría y la minoría) y analice las perspectivas esquizoanalíticas que sustentan su rechazo de la diferencia sexual y su mirada crítica acerca de algunas luchas feministas. Este trabajo explora, adicionalmente, en qué posición se puede situar a Deleuze en la polémica entre las teóricas del dimorfismo y las partidarias del género, respecto de lo cual sugerimos la posibilidad de inscribirlo en una orientación posgenérica.; This article investigates the concept of becoming-woman and some of the debates it has provoked in the reception of Deleuze within the field of feminist and gender studies. Interpretations have been predominantly negative based on criticisms of various kinds: the meaning of the concept is unclear and undefined; it lacks political efficacy due to its disconnection with the concrete struggles of actually existing women; it conceals masculine and ethnocentric, androgynous or even patriarchal positions; it leads to a post-feminist horizon that dissolves women's identity and invisibilises their claims for recognition; it ignores the epistemological and political importance of sexual difference. The hypothesis proposed in this paper is that these criticisms can be discussed with arguments grounded in a rigorous re-reading of this concept in Deleuzian work, that recovers key distinctions (the molar and the molecular, the majority and the minority) and analyses the schizoanalytic perspectives that underpin his rejection of sexual difference and his critical view on some feminist struggles. This paper further explores where Deleuze can be positioned in the debate between dimorphism theorists and gender partisans and suggests the possibility of inscribing him in a postgenderist orientation.

On the correlation between the noise and a priori error vectors for standard and augmented affine projection algorithms

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On the correlation between the noise and a priori error vectors for standard and augmented affine projection algorithms Altieri, Andrés Oscar This paper analyzes the correlation matrix between the a priori error and measurement noise vectors for standard and augmented affine projection algorithms using a unified approach. This correlation stems from the dependence between the filter tap estimates and the noise samples, and has a strong influence on the mean square behavior of the algorithm. We show that the correlation matrix is upper triangular, and compute the diagonal elements in closed form, showing that they are independent of the input process statistics. Also, for white inputs we show that the matrix is fully diagonal. These results are valid in the transient and steady states, considering a possibly variable step-size. Our only assumption is that the filter order is large compared to its projection order and that the input signal is stationary. Using these results, we perform a steady-state analysis for small step size and provide a new simple closed-form expression for the mean-square error, which has comparable or better accuracy to many preexisting expressions, and is much simpler to compute. Finally, we also obtain expressions for the steady-state energy of the other components of the error vector.

Psychosocial Maturity assessment in juvenile justice: A content validity analysis of a novel tool

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Psychosocial Maturity assessment in juvenile justice: A content validity analysis of a novel tool; Evaluación de la Madurez Psicosocial en Justicia Juvenil: Análisis de la validez de contenido de una herramienta novedosa Palacios van Isschot, Elena; Arbach, Karin; Andrés Pueyo, Antonio La madurez psicosocial (MP) es un factor potencial que influye en la toma de decisiones de los adolescentes y su comportamiento social e interpersonal. El estudio actual representa un primer paso para diseñar una nueva prueba de madurez psicosocial adecuada para evaluar este constructo en el contexto forense y en entornos de justicia juvenil. Su objetivo es establecer la validez de contenido para una nueva herramienta de evaluación. Después de una revisión de la literatura, se seleccionaron 38 ítems de diversas medidas y protocolos específicos existentes y se instruyó a 41 expertos para llevar a cabo un análisis de validez de contenido. Los resultados del Índice de Validez de Contenido muestran que el 92% de los ítems analizados fueron clasificados por los expertos como representativos del constructo, y los resultados del Índice de Validez Factorial muestran que los expertos asociaron el 79% de los ítems al constructo propuesto. En conclusión, la mayoría de los ítems se consideraron representativos del constructo y de sus componentes individuales, proporcionando una buena base para desarrollar una herramienta de evaluación de la MP. Se plantea la relevancia e implicaciones de los resultados en las tareas judiciales.; Psychosocial maturity (PM) is a potential factor influencing adolescent decision making and a wide range of social and interpersonal behaviors in adolescents. The current study represents an initial effort to design a new psychosocial maturity test suitable for assessing this construct in the forensic context and juvenile justice settings. Its aim is to establish content validity for a novel assessment tool. After a literature review, 38 items were selected from various existing specific tests and protocols, and 41 experts were instructed to conduct a content validity analysis on them. Content Validity Index results show that 92% of the items were classified by experts as representative to the construct, and Factorial Validity Index results show that experts associated 79% of the items with the correct component of the construct according to theoretical criteria. In conclusion, the majority of items were found to be representative of the construct and of their individual components, providing a valid foundation for the development of a new PM assessment tool. In this study the relevance and implications of the results for judicial tasks are discussed.

Diversity and molecular characterization of insect-specific flaviviruses in mosquitoes (Diptera: Culicidae) collected in central and northern Argentina

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Diversity and molecular characterization of insect-specific flaviviruses in mosquitoes (Diptera: Culicidae) collected in central and northern Argentina Farias, Adrian Alejandro; Labordolive, Victoria; Stein, Marina; Dantur Juri, Maria Julia; Visintin, Andrés; Almirón, Walter R.; Contigiani de Minio, Marta Silvia; Ré, Viviana Elizabeth; Diaz, Luis Adrian The genus Flavivirus comprises approximately 80 different viruses. Phylogenetic relationships among its members indicate a clear ecological separation between those viruses transmitted by mosquitoes, ticks, with no known vector, and insect-specific Flaviviruses. The diversity and phylogenetic relationships among insectspecific flaviviruses circulating in the central and northern regions of Argentina were studied by performing molecular detection and characterization of the NS5 protein gene in mosquitoes collected in Córdoba, Chaco and Tucumán provinces. Overall, 68 out of 1776 pools were positive. CxFV, KRV and CFAV circulate in the 3 studied provinces. Several mosquito species (Aedes aegypti, Culex bidens, Cx. dolosus, Cx. interfor, Cx. quinquefasciatus, Cx. saltanensis, Haemagogus spegazzini) were found infected. A wide circulation of CxFV was observed in the central-northern region of Argentina. CxFV strains detected in our study clustered with strains circulating in Santa Fe and Buenos Aires provinces (Argentina), and other countries such as Indonesia, Mexico, Uganda and Taiwan. The presence of these viruses in mosquitoes could play an important role from the public health perspective, because it has been shown that previous CxFV infection can increase or block the infection of the mosquito by other pathogenic flaviviruses.

Lotus spp.: a Mediterranean genus with high environment and economic impact in the Salado River Basin (Argentina)

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Lotus spp.: a Mediterranean genus with high environment and economic impact in the Salado River Basin (Argentina) Ruiz, Oscar Adolfo; Gortari, Maximiliano; Maguire, Vanina Giselle; Arese, Romina Paola; Campestre, Maria Paula; Antonelli, Cristian Javier; Calzadilla, Pablo Ignacio; Menendez, Ana Bernardina; Escaray, Francisco José; Carrasco Sorli, Pedro Miguel; Bailleres, Matías Andres; Ezquiaga, Juan Pedro; Paolocci, Francesco; Gárriz, Andrés; Nieva, Amira Susana del Valle This review has the principal objective in to hypothesise that the introduction of Lotus species could have significant benefts in constrained soils due their worldwide distribution. This idea is major based on results obtained in the lowlands of the most important livestock breeding area in Argentina denominated Salado River Basin (also called “Flooding Pampas”). Mostly of their land surface is dominated by salt-afected soils with severe constraints for traditional crop cultivation (i.e., maize, soybean, etc.). In order to increase their economic importance, farmers have utilized species suchas non-native L. tenuis (ex- Lotus glaber), originating from European Mediterranean area, which shows a successfully and fast naturalization (in less than 60 years) in constrained areas improving forage performance. The increase in soil quality associated to this legume is achieved by an increment of the organic matter content and improvement of fertility and physicochemical parameters. Moreover, other studies have evidenced some genetic determinants associated with interesting agronomic traits such as plant tolerance to environmental stresses and the importance of leaves condensed tannins concentrations. This revision has many topics including a brief analysis of economic and environmental changes that occur under Lotus species implantation. In addition, we incorporate references recently published concerning the evaluation of the biochemical and physiological mechanisms involved in their adaptation to strong abiotic stresses characteristic of the region, the soil and plant microbiota diversity and soil physical and chemical characteristics associated to the presence of Lotus genotypes.

The Argentine economy through the lens of an adapted Mundell–Fleming model for small open peripheral economies

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The Argentine economy through the lens of an adapted Mundell–Fleming model for small open peripheral economies Dvoskin, Ariel; Feldman, Germán David; Torchinsky Landau, Matías This paper investigates the limits fiscal and monetary policies face in small openeconomies, where economic growth can be constrained by the balance of payments.To do so, we proceed in three steps. First, we review some usually neglected stringentassumptions of the Post-Keynesian interpretation of the IS-LM-BP model, regarding theroles played by the exchange rate and the interest rate in re-establishing external equilibrium. Second, we adapt this model to consider the specificities of peripheral economies. Third, we illustrate the model’s functionality and implications, drawing upon the experience of the Argentine economy, a country where the external sector has recurrently constrained output growth.

Sufficient dimension reduction for a novel class of zero-inflated graphical models

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Sufficient dimension reduction for a novel class of zero-inflated graphical models Koplin, Eric Lionel; Forzani, Liliana Maria; Tomassi, Diego Rodolfo; Pfeiffer, Ruth M. Graphical models allow modeling of complex dependencies among components of a random vector. In many applicationsof graphical models, however, for example microbiome data, the data have an excess number of zero values. Wepresent new pairwise graphical models with distributions in an exponential family, that accommodate excess numbersof zeros in the random vector components. First we characterise these multivariate distributions in terms of univariateconditional distributions. We then model predictors that arise from such a pairwise graphical model with excess zerosas a function of an outcome, and derive the corresponding first order sufficient dimension reduction (SDR). That is,we find linear combinations of the predictors that contain all the information for the regression of the outcome as afunction of the predictors. We estimate the SDR using pseudo-likelihood with a hierarchical penalty that accounts forthe graphical model structure, for variable selection, by allowing interactions only for variables that are associatedwith outcome also through main effects. This method yields consistent estimators of the reduction and can be appliedto continuous or categorical outcomes. We then illustrate our methods by studying normal, Poisson and truncatedPoisson graphical models with excess zeros in simulations and by analyzing microbiome data from the AmericanGut Project. Our models provided robust variable selection and the Poisson zero-inflation pairwise graphical modelresulted in predictive performance that was equal or better than that obtained from applying other available methodsfor the analysis of microbiome data.

Validity and Reproducibility of an Electronic Food Frequency Questionnaire in Argentinian Adults

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Validity and Reproducibility of an Electronic Food Frequency Questionnaire in Argentinian Adults Gili, Rocio Victoria; Leeson, Sara; Carlino, Belén; Contreras Guillen, Ismael Alejandro; Xutuc, Daniel; Martins, Marcia Cristina Teixeira; Díaz, María del Pilar; Segovia-siapco, Gina; Oliveira Da Silva Pacheco, Sandaly; Pacheco, Fabio Juliano This study aimed to validate a semiquantitative electronic food frequency questionnaire (eFFQ) in estimating the intake of a comprehensive list of nutrients and bioactive compounds among adults from six regions of Argentina using multiple 24 h dietary recall (24HR) as a reference. A total of 163 adults completed two administrations of the eFFQ and four 24HRs. The paired t-test/Wilcoxon signed-rank test, Spearman/Pearson correlations, cross-classification, weighted kappa statistics, and Bland–Altman plots were employed to determine relative validity. To determine reproducibility, intraclass correlations (ICC), cross-classification, and weighted kappa statistics were calculated. For relative validity, crude correlations ranged from 0.15 to 0.57; energy adjustment and de-attenuation slightly improved most of these correlations. In cross-classification analysis, agreements within one quintile adjacent to exact agreement (EA ± 1) ranged from 52.2% to ~74%; extreme misclassifications were < 7%. For reproducibility, the crude ICC ranged from 0.29 to 0.85, showing moderate to good correlations for most nutrients. Cross-classification analysis showed agreement levels for the EA ± 1 quintile of 70.6% to 87.7%. Weighted kappa values ranged from 0.21 to 0.62. The results show that this eFFQ is relatively valid in ranking adults according to their nutrient intake and has an acceptable reproducibility, yet it slightly overestimates the intake of most nutrients.

Young Plasma Rejuvenates Blood DNA Methylation Profile, Extends Mean Lifespan, and Improves Physical Appearance in Old Rats

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Young Plasma Rejuvenates Blood DNA Methylation Profile, Extends Mean Lifespan, and Improves Physical Appearance in Old Rats Chiavellini, Priscila; Lehmann, Marianne; Gallardo, Maria D.; Canatelli Mallat, Martina; Pasquini, Diana Camila; Zoller, Joseph A.; Gordevicius, Juozas; Girard, Mauricio; Lacunza, Ezequiel; Hereñú, Claudia Beatriz; Horvath, Steve; Goya, Rodolfo Gustavo There is converging evidence that young blood conveys cells, vesicles, and molecules able to revitalize function and restore organ integrity in old individuals. We assessed the effects of young plasma on the lifespan, epigenetic age, and healthspan of old female rats. Beginning at 25.6 months of age, a group of 9 rats (group T) was intraperitoneally injected with plasma from young rats until their natural death. A group of 8 control rats of the same age received no treatment (group C). Blood samples were collected every other week. Survival curves showed that from age 26 to 30 months, none of the group T animals died, whereas the survival curve of group C rats began to decline at age 26 months. Blood DNAm age versus chronological age showed that DNAm age in young animals increased faster than chronological age, then slowed down, entering a plateau after 27 months. The DNAm age of the treated rats fell below the DNAm age of controls and, in numerical terms, remained consistently lower until natural death. When rats were grouped according to the similarities in their differential blood DNA methylation profile, samples from the treated and control rats clustered in separate groups. Analysis of promoter differential methylation in genes involved in systemic regulatory activities revealed specific GO term enrichment related to the insulin-like factors pathways as well as to cytokines and chemokines associated with immune and homeostatic functions. We conclude that young plasma therapy may constitute a natural, noninvasive intervention for epigenetic rejuvenation and health enhancement.

Regulación de intermediarios de Internet: Análisis de los Foros Latinoamericanos de Gobernanza (2018-2021)

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Regulación de intermediarios de Internet: Análisis de los Foros Latinoamericanos de Gobernanza (2018-2021); Internet intermediaries’ regulation: Analysis of the Latin American Governance Forums (2018-2021); Regulamentação de intermediários da Internet: Análise dos Fóruns de Governança Latino-Americanos (2018-2021) Bizberge, Ana; Mastrini, Guillermo Néstor Este artículo analiza la regulación de intermediarios en los Foros de Gobernanza de Internet de América Latina entre 2018 y 2021, desde la perspectiva de las políticas públicas de comunicación. Se indagan los temas, actores y su posicionamiento sobre los derechos humanos y la libertad de expresión a partir de la revisión de videos y relatorías de los foros. El artículo concluye que el abordaje de derechos humanos se desplaza de la libertad de expresión hacia la privacidad. El trabajo busca contribuir a la comprensión de los debates emergentes sobre regulación de Internet en la región.; This article analyzes Internet intermediaries’ regulation in the Latin American Governance Forums between 2018-2021 with the approach of public policy in communications. The topics, actors and their position on human rights and freedom of expression are examined based on the review of videos and reports of the forums. The article concludes that the human rights approach shifts from freedom of expression to privacy. The paper aims to make a contribution to the understanding of the emerging debates on Internet regulation in the region.; Este artigo analisa a regulação dos intermediários nos Fóruns Latino-Americanos de Governança da Internet entre 2018 e 2021, sob a perspectiva das políticas públicas de comunicação. Os temas, atores e sua posição sobre direitos humanos e liberdade de expressão são investigados a partir da análise de vídeos e reportagens dos fóruns. O artigo conclui que a abordagem dos direitos humanos muda da liberdade de expressão para a privacidade. O trabalho busca contribuir para a compreensão dos debates emergentes sobre a regulação da Internet na região.

El concepto de amor y lo político en la ética política kantiana

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El concepto de amor y lo político en la ética política kantiana; The concept of love and the political in Kantian political ethics Quiroga, Noelia Eva El propósito de este trabajo es ofrecer una lectura ético-política del amor en la ética de la virtud kantiana contenida en la Religión dentro de los límites de la mera Razón y en la Metafísica de las Costumbres. Para ello, en primer lugar, estudiaré el problema que presenta el amor propio entendido como un posible obstáculo para el amor hacia los demás, con quienes interactuamos. En segundo lugar, estudiaré cómo la idea de amor práctico en la ética de la virtud kantiana, da lugar, en el ámbito de la relación con los otros, al deber de amar al prójimo y contribuir con su felicidad. Finalmente, estudiaré cómo la ética política kantiana, encarnada en la idea de la comunidad ética, expresa una ética del amor que permite contrarrestar el exceso de amor propio.; The purpose of this work is to offer an ethical-political reading of love in the Kantian virtue ethics expressed in Religion within the Boundaries of Mere Reason and in The Metaphysics of Morals. To this end, in the first place, I will study the problem that self-love presents, understood as a possible obstacle to love towards others with whom we interact. Secondly, I will study how the idea of practical love, in Kantian virtue ethics, gives rise in the realm of relationships with others to the duty to love one’s neighbor and contribute to his happiness. Finally, I will study how the Kantian political ethics, embodied in the idea of the ethical community, expresses an ethics of love that allows to counteract the excess of self-love.

Producción y reproducción de discursos sexo-generizados a través de la cultura física oficial: Consecuencias en la formación de profesionales en Educación Física en Argentina (1937-1939)

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Producción y reproducción de discursos sexo-generizados a través de la cultura física oficial: Consecuencias en la formación de profesionales en Educación Física en Argentina (1937-1939); The production and reproduction of sex-gendered discourses through official physical culture: Consequences in the training of professionals in physical education in Argentina (1937-1939) Boyezuk, Agustina; Galak, Eduardo La propuesta de este escrito es interpretar la construcción de discursos sexo-generizados que orbitaron la educación de los cuerpos y las sensibilidades en la cultura física oficial en argentina, a través de analizar la institucionalización de la Educación Física en un momento bisagra de la disciplina a finales de la década de 1930. Se trata de un contexto reformista en el que emerge el segundo Instituto Nacional, producto de la creación de la Dirección General de Educación Física en 1938 que instaura modificaciones estructurales para la disciplina. Se parte como hipótesis que el proyecto educativo de cultura física estuvo atravesado por un conjunto de modificaciones macro políticas estatales características del segundo cuarto del siglo XX argentino, que generaron una nueva organización institucional de los procesos de escolarización (Puiggrós, 1996; Scharagrodsky & Southwell, 2007), lo cual se reflejó en un cambio de paradigma que se materializó en esas dos instituciones estatales que abordaron respectivamente la formación y el ejercicio profesional. Más allá de haber reproducido prácticas, saberes y discursos que estaban en tensión por aquellos años, estos establecimientos funcionaron como dispositivos político-estetizantes que configuraron sentidos sexo-generizados, reproduciendo una gramática de lo corporal (Galak, 2020) y contribuyendo en la construcción de sensibilidades que asociaron a los modos de hacer particulares modos de ser (Chihuailaf Vera, Mujica Johnson & Concha López, 2022). Para ello se analizan un conjunto de documentos oficiales, principalmente los Boletines del Ministerio de Justicia e Instrucción Pública (Argentina, 1938-1939) y los Registros de Clasificación, cuadernos de los institutos de formación profesional donde figuraban las notas de evaluación.; This paper aims to interpret the construction of sex-gendered discourses that orbited the education of bodies and sensibilities in physical culture in Argentina by analysing the institutionalisation of Physical Education at a turning point in the discipline at the end of the 1930s. In the reformist context, the second National Institute emerged as a new establishment dedicated to professionalisation. This was a result of the creation of the General Directorate of Physical Education in 1938, which introduced structural modifications to the discipline. The educational project of physical culture in Argentina during the second quarter of the 20th century was influenced by a set of state macro-political modifications. These modifications led to a new institutional organisation of schooling processes, as noted by Puiggrós (1996), and Scharagrodsky & Southwell (2007). This change of paradigm was reflected in two state institutions that dealt with training and professional practice. In addition to reproducing practices, knowledge, and discourses that were in tension during that time, these establishments functioned as political aesthetic devices that created meanings related to sex, reproducing a bodily grammar (Galak, 2020) and contributing to the construction of sensibilities that associated specific ways of being with particular ways of doing. To achieve this, it is analysed a set of official documents, including the Boletines of the Ministry of Justice and Public Instruction (Argentina, 1938-1939) and the Registros de Clasificación, qualification notebooks used by higher education institutes to record grades.

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