Sindicador de canales de noticias
On-Farm single strip treatment trials
The dataset comprises data collected from six unreplicated on-farm experiments (OFE) conducted in Córdoba, central Argentina. These experiments included three field trials of corn (Zea mays L.), designated as F1, F2, and F3, and three field trials of soybean (Glycine max (L.) Merr.), designated as F4, F5, and F6. Trials F1 and F6 were conducted under irrigated conditions, while the others were rainfed. In F1, the effects of a starter fertilizer on corn were assessed using two single strips: Treated, with a fertilizer application rate of 100 kg ha–1 [21-17-3 + 1% MgO + 5% S + 0.1% Zn], and Control, with no fertilizer (0 kg ha–1). Each strip was 1.1 ha in area, totaling 34 ha. In F2, the impact of broadcast phosphorus (P) fertilization was evaluated. The treatment strip received superphosphate at rates ranging from 250 to 500 kg ha–1 [0-21-0], while the control strip received no P fertilizer (0 kg ha–1). Each strip was 2.2 ha in area, totaling 100 ha. In F3, the OFE focused on the effect of foliar zinc application at the V4 growth stage. The treated strip received a dose of 2 L ha-1 (700 g L-1), while the control strip received no zinc (0 L ha-1). Each individual strip was 2 ha in area (500 m long × 40 m wide), totaling 68 ha. In F4 and F6, the effectiveness of foliar boron (B) fertilization at the R3 growth stage was evaluated. For F4, the treated strip, which covered an area of 2 ha (680 x 30 m), received 1 L ha–1 (150 g L-1), while the control strip received no boron (0 L ha–1), and was 1.8 ha in area (640 m x 30 m) on a 42-ha field. For F6, the treated strip received 2 L ha–1 (150 g L-1) and covered an area of 4.9 ha, while the control strip (0 L ha–1) covered 7.5 ha on a 59-ha field. In F5, the OFE assessed the impact of broadcast phosphorus (P) fertilization on soybean. The treated strip received triple superphosphate containing calcium at rates ranging from 250 to 500 kg ha–1 [0-46-0 + 15% Ca], while the control strip received no P fertilizer (0 kg ha–1). The plot covered 61 ha, with strip dimensions of 450 x 50 m, resulting in areas of 2.3 ha for the treatment and control.
ALMA-IMF, X : The core population in the evolved W33-Main (G012.80) protocluster
ALMA-IMF, X : The core population in the evolved W33-Main (G012.80) protocluster
Armante, M.; Gusdorf, A.; Louvet, F.; Motte, F.; Pouteau, Y.; Lesaffre, P.; Galván Madrid, R.; Della Vedova, Juan Pablo; Bonfand, M.; Nony, T.; Brouillet, N.; Cunningham, N.; Ginsburg, A.; Men’shchikov, A.; Bontemps, Sophie; Díaz González, D.; Csengeri, T.; Fernandez Lopez, Manuel; González, M.; Herpin, F.; Liu, H. L.; Sanhueza, P.; Stutz, A.M.; Valeille Manet, M.
Context. One of the central questions in astrophysics is the origin of the initial mass function (IMF). It is intrinsically linked to the processes from which it originates, and hence its connection with the core mass function (CMF) must be elucidated.Aims: We aim to measure the CMF in the evolved W33-Main star-forming protocluster to compare it with CMF recently obtained in other Galactic star-forming regions, including the ones that are part of the ALMA-IMF program.Methods: We used observations from the ALMA-IMF large programme: ~2´ × 2´ maps of emission from the continuum and selected lines at 1.3 mm and 3 mm observed by the ALMA 12m only antennas. Our angular resolution was typically 1″, that is, ~2400 au at a distance of 2.4 kpc. The lines we analysed are CO (2-1), SiO (5-4), N2H+ (1-0), H41α as well as He41α blended with C41α. We built a census of dense cores in the region, and we measured the associated CMF based on a core-dependent temperature value.Results: We confirmed the `evolved´ status of W33-Main by identifiying three H II regions within the field, and to a lesser extent based on the number and extension of N2H+ filaments. We produced a filtered core catalogue of 94 candidates that we refined to take into account the contamination of the continuum by free-free and line emission, obtaining 80 cores with masses that range from 0.03 to 13.2 M⊙. We fitted the resulting high-mass end of the CMF with a single power law of the form N(log(M)) ∝ Mα, obtaining α = −1.44−0.22+0.16, which is slightly steeper but consistent with the Salpeter index. We categorised our cores as prestellar and protostellar, mostly based on outflow activity and hot core nature. We found the prestellar CMF to be steeper than a Salpeter-like distribution, and the protostellar CMF to be slightly top heavy. We found a higher proportion of cores within the H II regions and their surroundings than in the rest of the field. We also found that the cores´ masses were rather low (maximum mass of ~13 M⊙).Conclusions: We find that star formation in W33-Main could be compatible with a `clump-fed´ scenario of star formation in an evolved cloud characterised by stellar feedback in the form of H II regions, and under the influence of massive stars outside the field. Our results differ from those found in less evolved young star-forming regions in the ALMA-IMF program. Further investigations are needed to elucidate the evolution of late CMFs towards the IMF over statistically significant samples.
Unveiling the Structural Properties, Optical Behavior, and Thermoelectric Performance of 2D CsSn 2 Br 5 Halide Obtained by Mechanochemistry
Unveiling the Structural Properties, Optical Behavior, and Thermoelectric Performance of 2D CsSn 2 Br 5 Halide Obtained by Mechanochemistry
Lopez, Carlos Alberto; Abia, Carmen; Gainza, Javier; Rodrigues, João Elias; Martinelli, Brenda; Serrano Sánchez, Federico; Santos Silva, Romualdo; Ferrer, Mateus M.; Dura, Oscar J.; Martínez, José Luis; Fernández Díaz, María Teresa; Alonso, José Antonio
Metal halide perovskites with a two-dimensional structure are utilized in photovoltaics and optoelectronics. High-crystallinity CsSn2Br5 specimens have been synthesized via ball milling. Differential scanning calorimetry curves show melting at 553 K (endothermic) and recrystallization at 516 K (exothermic). Structural analysis using synchrotron X-ray diffraction data, collected from 100 to 373 K, allows for the determination of Debye model parameters. This analysis provides insights into the relative Cs–Br and Sn–Br chemical bonds within the tetragonal structure (space group: I4/mcm), which remains stable throughout the temperature range studied. Combined with neutron data, X–N techniques permit the identification of the Sn2+ lone electron pair (5s2) in the two-dimensional framework, occupying empty space opposite to the four Sn–Br bonds of the pyramidal [SnBr4] coordination polyhedra. Additionally, diffuse reflectance UV–vis spectroscopy unveils an indirect optical gap of approximately ∼3.3 eV, aligning with the calculated value from the B3LYP-DFT method (∼3.2 eV). The material exhibits a positive Seebeck coefficient as high as 6.5 × 104 μV K–1 at 350 K, which evolves down to negative values of −3.0 × 103 μV K–1 at 550 K, surpassing values reported for other halide perovskites. Notably, the thermal conductivity remains exceptionally low, between 0.32 and 0.25 W m–1 K–1.
Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis
Elevated glycolytic metabolism of monocytes limits the generation of HIF-1α-driven migratory dendritic cells in tuberculosis
Maio, Mariano Nicolas; Barros, Joaquina; Marin Franco, Jose Luis; Genoula, Melanie; Vecchione, María Belén; Fuentes, Federico; Gonzalez Polo, Virginia; Quiroga, María Florencia; Vermeulen, Mónica; Musella, Rosa María; Ciallella, Lorena María Cecilia; González Montaner, Pablo; Palmero, Domingo; Sasiain, María del Carmen; Balboa, Luciana
During tuberculosis, migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the rapid development of protective T-cell mediated immunity. However, the mechanisms involved in the delayed migration of DCs during TB are still poorly defined. Here, we found that infection of DCs with Mycobacterium tuberculosis triggers HIF-1α-mediated aerobic glycolysis in a TLR2-dependent manner, and that this metabolic profile is essential for DC migration. In particular, the glycolysis inhibitor oxamate and the HIF-1α inhibitor PX-478 abrogated M. tuberculosis-induced DC migration in vitro to the lymphoid tissue-specific chemokine CCL21, and in vivo to lymph nodes in mice. Strikingly, we found that although monocytes from TB patients are inherently biased toward glycolysis metabolism, they differentiate into poorly glycolytic and poorly migratory DCs, compared with healthy subjects. Taken together, these data suggest that because of their preexisting glycolytic state, circulating monocytes from TB patients are refractory to differentiation into migratory DCs, which may explain the delayed migration of these cells during the disease and opens avenues for host-directed therapies for TB.
The immunosuppressive tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4+ T cells
The immunosuppressive tuberculosis-associated microenvironment inhibits viral replication and promotes HIV-1 latency in CD4+ T cells
Cronin, Samantha; de Vries Egan, Anneke; Vahlas, Zoï; Czernikier, Alejandro; Melucci Ganzarain, Claudia del Carmen; Pereyra Gerber, Federico Pehuén; O’Neil, Thomas; Gloss, Brian; Sharabas, Mayssa; Turk, Gabriela Julia Ana; Verollet, Christel; Balboa, Luciana; Palmer, Sarah; Duette, Gabriel
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is the most common coinfection among people living with HIV-1. This coinfection is associated with accelerated HIV-1 disease progression and reduced survival. However, the impact of the HIV-1/TB coinfection on HIV-1 replication and latency in CD4+ T cells remains poorly studied. Using the acellular fraction of tuberculous pleural effusion (TB-PE), we investigated whether viral replication and HIV-1 latency in CD4+ T cells are affected by a TBassociated microenvironment. Our results revealed that TB-PE impaired T cell receptor-dependent cell activation and decreased HIV-1 replication in CD4+ T cells. Moreover, this immunosuppressive TB microenvironment promoted viral latency and inhibited HIV-1 reactivation. This study indicates that the TB-induced immune response may contribute to the persistence of the viral reservoir by silencing HIV-1 expression, allowing the virus to persist undetected by the immune system and increasing the size of the latent HIV-1 reservoir.
La imagen sublevada en el audiovisual colombiano: De El caballero de la fe a Pirotecnia
La imagen sublevada en el audiovisual colombiano: De El caballero de la fe a Pirotecnia; The Uprised Image in the Colombian Audiovisual: El caballero de la fe, Bicentenario and Pirotecnia
Delgado Marulanda, Alba Lucía; Henao Jaramillo, Simón
En el marco de una investigación mayor acerca de la duración en el arte, el cine y la literatura en Colombia, en este trabajo realizamos un estudio de caso de un corpus conformado por la videoinstalación El caballero de la fe, de José Alejandro Restrepo (2011), y los ensayos fílmicos Pirotecnia (2019), de Federico Atehortúa, y Bicentenario, de Pablo Álvarez (2020). La hipó-tesis que desarrollamos afirma que estas piezas audiovisuales colombianas contemporáneas, mediante un uso de los recursos técnicos disponibles puestos sobre la materialidad de lo visual, transforman, reescriben, subvierten y sublevan el sentido de las imágenes. Son obras que, por un lado, dislocan el tiempo registrado de las imágenes al intervenir en sus tiempos, en las gradaciones de su intensidad y en los movimientos de sus elementos y, a su vez, los recolocan en el tiempo proyectado como parte del proceso de sublevación de la imagen.; In the framework of a greater investigation about the duration in art, cinema and literature in Colombia, in this work we study a corpus made up of the video installation El caballero de la fe, by José Alejandro Restrepo (2011), and the filmic essays Pirotecnia (2019), by Federico Atehortúa, and Bicentenario, by Pablo Álvarez (2020). The hypothesis that we develop affirms that these contemporary Colombian audiovisual works, through a use of the available technical resources placed on the materiality of the visual, transform, rewrite, subvert and rebel the sense of the images. These are works that, on the one hand, dislocate the registered time of the images by intervening in their times, in the gradations of their intensity and in the movements of their elements, and in turn relocate them in the projected time as part of the uprising process of the picture.
“El método filológico sigue siendo esencialmente el mismo, no importa cuál sea el material”: Acerca del epistolario entre Rodolfo Lenz y Franz Boas
“El método filológico sigue siendo esencialmente el mismo, no importa cuál sea el material”: Acerca del epistolario entre Rodolfo Lenz y Franz Boas; “The Philological Method Remains Essentially the Same, No Matter Which Material It Is”: On the Correspondence Between Rodolfo Lenz and Franz Boas
Ennis, Juan Antonio; Soltmann, Claudio
Este artículo propone ofrecer una descripción y análisis inicial del material conservado en el Fondo Lenz, custodiado por la Universidad Metropolitana de Ciencias de la Educación en Santiago de Chile, y mayormente entre los Franz Boas Papers de la American Philosophical Society, correspondiente al intercambio epistolar sostenido entre 1896 y 1931 entre el lingüista germano-chileno Rodolfo Lenz y el antropólogo germano-norteamericano Franz Boas. Se trata de un corpus de unas 17 cartas, en las que ambos científicos intercambian materiales e información sobre el desarrollo de sus estudios, especialmente en lo respectivo a la lengua y la cultura de los pueblos originarios del continente americano, así como a los avances y dificultades en la generación de condiciones de posibilidad propicias para el desarrollo de las disciplinas científicas abocadas a ese estudio.; The aim of this paper is to offer an initial description and analysis of the material preserved at the Fondo Lenz, kept by the Universidad Metropolitana de Ciencias de la Educación in Santiago de Chile, and mainly among the Franz Boas Papers of the American Philosophical Society, concerning the letter exchange between the German-Chilean linguist Rodolfo Lenz and the German-American anthropologist Franz Boas, from 1896 to 1931. It consists of a corpus of 17 letters, in which both scientists exchange materials and information on the development of their research, especially regarding the study of language and culture of the native peoples of the American continent, as well as the development and challenges in the production of proper conditions for the progress of research on such scientific subjects.
Una cuestión de escalas: Cybernaturaleza, sexualidad y capitalismo en El auge del humano de Eduardo Williams
Una cuestión de escalas: Cybernaturaleza, sexualidad y capitalismo en El auge del humano de Eduardo Williams
Rubino, Atilio Raúl
Este artículo analiza la película de Eduardo Williams El auge de lo humano (2016) como ficción audiovisual especulativa a partir de algunas concepciones que plantean la crisis de la episteme moderna sobre lo humano. El primer largometraje de Williams conecta a través de la tecnología y de la naturaleza tres espacios, Argentina, Mozambique y Filipinas, y no tiene una historia central o un conflicto dramático, sino que la cámara sigue a los personajes en el recorrido por distintos lugares casi en un registro documental. Pero a su vez la espacialidad y la temporalidad está trastocada generando un tiempo-espacio que no es ni distópico ni utópico, ni especulación tecnológica ni pre-historia sino que se sitúa en los intermedios, en los bordes, encontrando allí algunas posibilidades de resistencia a los flujos constantes del capitalismo mundial. Resulta, de esta forma, una película que podemos considerar rara en los términos en los que lo entiende Fisher (2018), ya que los pasajes, pasadizos, laberintos, madrigueras y agujeros cumplen un rol fundamental en la construcción de los espacios especulativos que se parecen mucho más a nuestro presente tercermundista que a los imaginarios mainstream de la ciencia ficción. En ese sentido, la película de Williams imagina desde lo cinematográfico un futuro en el que la experiencia de lo raro se instaura para romper con la centralidad del humano y, con ello, de la familia nuclear burguesa y el binarismo entre hetero y homosexualidad.; This article analyzes Eduardo Williams’ film The Human Surge (2016) as a speculative audiovisual fiction, drawing from concepts that address the crisis of the modern episteme on what’s human. Williams’ first feature film connects three spaces -Argentina, Mozambique, and the Philippines- through technology and nature. It doesn’t have a central storyline or a dramatic conflict; instead, the camera follows the characters as they walk through various locations, almost in a documentary style. Simultaneously, both the spatiality and temporality are disrupted, creating a time-space that is neither dystopian nor utopian, neither technological speculation nor pre-history. Instead, it places itself in the intermediaries, on the margins, finding possibilities for resistance to the constant flows of global capitalism. Therefore, the film can be considered ‘weird’ in Fisher’s (2018) terms, as passageways, corridors, labyrinths, burrows, and holes play a fundamental role in constructing speculative spaces that resemble our present in this developing world more than the mainstream imaginaries of science fiction. In this sense, Williams’ feature film envisions, cinematically, a future in which the experience of what’s weird is established to break with the centrality of what’s human and, consequently, the bourgeois nuclear family and the binary between heterosexuality and homosexuality.
El Punitivismo y el Autoritarismo en relación con las nuevas políticas de derecha
El Punitivismo y el Autoritarismo en relación con las nuevas políticas de derecha
Roca, Marcelo Agustin
El artículo no presenta resumen según el formato editorial de la revista
La miniatura épica en el L. II de la Rusticatio Mexicana
La miniatura épica en el L. II de la Rusticatio Mexicana; The epic miniature in the Book II of the Rusticatio Mexicana
Suarez, Marcela Alejandra
En el vasto panorama de la literatura neolatina la poesía épica y la poesía didáctica ocupan el sitial más destacado dentro de la jerarquía de los géneros poéticos. En términos generales, comparten una serie de rasgos comunes tales como el mismo metro, la división en cantos, elaboradas comparaciones, largos pasajes descriptivos y narrativos. La Rusticatio Mexicana del jesuita novohispano Rafael Landívar, publicada en Bolonia en 1782, es un poema didáctico-descriptivo en el que se celebran las excelencias americanas a partir de la constitución previa de un modelo de competencia genérica surgido básicamente de las Geórgicas de Virgilio. Sin embargo, el poema también presenta algunos rasgos vinculados con la estructura épica. En esta ocasión nos detendremos en el L.II, que aborda la descripción de la erupción del volcán Jorullo, y analizaremos la miniatura épica en torno del éxodo de los lugareños, cuyo hipotexto es el relato virgiliano de la destrucción de Troya. Esta tímida filiación con el género épico está convalidada por un corpus de alusiones pertenecientes a la Eneida, que el propio Landívar activa asimilando de este modo la historia de los nativos a la de los troyanos y sentando las bases de una épica local que puede ser interpretada como el vehículo metafórico del exilio jesuítico.; In the vast panorama of Neo-Latin literature, epic poetry and didactic poetry occupy the most prominent place in the hierarchy of poetic genres. Broadly speaking, they share a number of common features such as the same metre, division into chants, elaborate comparisons, long descriptive and narrative passages. The Rusticatio Mexicana by the new spanish jesuit Rafael Landívar, published in Bologna in 1782, is a didactic-descriptive poem in which american excellences are celebrated based on the previous constitution of a model of generic competence that basically emerged from the Georgics of Virgil. However, the poem also has some features linked to the epic structure. On this occasion we will stop at book II, which deals with the description of the eruption of the Jorullo volcano, and we will analyze the epic miniature around the exodus of the locals, whose hypotext is the virgilian account of the destruction of Troy. This timid affiliation with the epic genre is validated by a corpus of allusions belonging to the Aeneid, which Landívar himself activates, thus assimilating the history of the natives to that of the trojans and laying the foundations of a local epic that can be interpreted as the metaphorical vehicle of the Jesuit exile.
Reflexiones teóricas sobre la construcción conceptual de las experiencias organizativas de las asambleas antiextractivistas de La Rioja, Argentina
Reflexiones teóricas sobre la construcción conceptual de las experiencias organizativas de las asambleas antiextractivistas de La Rioja, Argentina; Theoretical reflections on the conceptual construction of the organizational experiences of the anti-extractivist assemblies of La Rioja, Argentina
Gasetúa, Erica Flavia
Este escrito es una introducción a la construcción teórico-epistémica, que como asamblearia feminista antiextractivista e investigadora llevo adelante en una investigación de tesis doctoral y de la lucha colectiva desplegada en los lugares de vida que habito. Las categorías que se proponen reflexionar, están siendo (Kusch, 2007) pensadas en lucha y desde las urgencias que permanentemente azotan nuestros territorios signados como zonas de sacrificio para el neoextractivismo. En esta presentación el objetivo es problematizar la categoría de asambleas socioambientales, con especial atención en lo socioambiental, su circulación y la revisión del propio recorrido de reflexión conceptual en mis escritos.; This writing is an introduction to the theoretical-epistemic construction, which as an anti-extractivist feminist assembly member and researcher I carry out in a doctoral thesis research and the collective struggle deployed in the places of life that I inhabit. The categories that are proposed to reflect are being (Kusch, 2007) conceived in struggle and from the urgencies that permanently plague our territories marked as sacrifice zones for neo-extractivism. In this presentation the objective is to problematize the category of socio-environmental assemblies, with special attention to the socio-environmental, its circulation and the review of the journey of conceptual reflection in my writings.
A quantitative analysis of David Fabricius’ astronomical observations
A quantitative analysis of David Fabricius’ astronomical observations
Grecco, Hernan Edgardo; Carman, Christian Carlos
David Fabricius, a Reformed pastor in Ostfriesland, was highly regarded by Kepler as an exceptional observer, second only to Tycho Brahe. From 1596 to 1609, Fabricius engaged in extensive correspondence, exchanging numerous letters with Brahe and subsequently with Kepler. These communications also provided values for direct observations on meridian altitudes of planets and stars, as well as elongations between a planet and a star or between two stars. We provide a detailed summary of Fabricius’s observations and compare them with the prediction of twenty-first-century models. The analysis indicates that under specific conditions, his observations exhibit sub-arcminute deviations in relation to those calculated from modern theories. Our findings preliminarily indicate that Fabricius’ astronomical observational abilities were comparable to, an occasionally superior to, those of Brahe himself. We provide machine-readable tables of his observations.
To move or not to move: Dispersal of Orius insidiosus in strawberry plants
To move or not to move: Dispersal of Orius insidiosus in strawberry plants
Alonso, Mariángeles; Guisoni, Nara Cristina; Rocca, Margarita; Greco, Nancy Mabel
Spatial and temporal distribution of food resources influences predatory insects´ foraging and dispersal behavior. Orius insidiosus (Say) (Hemiptera: Anthocoridae) is a good biological control agent of western flower thrips (WFT), Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae), in the strawberry crop and consumes two-spotted spider mite (TSSM), Tetranychus urticae Koch (Acari: Tetranychidae), and pollen as well. Augmentative biological control programs may fail if, following release, predators disperse from the crop. We studied the dispersal of O. insidiosus as a function of pollen availability, density of their main prey WFT, and the presence of the alternative prey TSSM, within and between strawberry plants. We found that O. insidiosus remained on the flowers during the 24h of the assay. The dispersal of predators to a neighboring flower with thrips was approximately six times greater from a flower without pollen than from a flower with pollen. When TSSM was the only prey available, O. insidiosus colonized the leaves, and its dispersal within the plant was greater. At the plot scale, the predator dispersal from the release plant to other plants also depended on the presence of flowering plants and prey. Our results highlight the importance of flowering plants and pollen availability in enhancing the persistence of O. insidiosus in strawberry plants. Releases of this predator in the strawberry crop should be after the beginning of flowering, even at low WFT densities.
Elucidating solvent effects on lipase‐catalyzed peroxyacid synthesis through activity‐based kinetics and molecular dynamics
Elucidating solvent effects on lipase‐catalyzed peroxyacid synthesis through activity‐based kinetics and molecular dynamics
Brandolin, Salvador Eduardo; Scilipoti, José Antonio; Magario, Ivana
Peroxyacid synthesis is the first step in Prilezhaev epoxidation, which is an industrial method to form epoxides. Motivated by the development of a kinetic model as a tool for solvent selection, the effect of solvent type and acid chain length on the lipase-catalyzed peroxyacid synthesis was studied. A thermodynamic activity-based ping-pong kinetic expression was successfully applied to predict the effect of the reagent loadings in hexane. The activity-based reaction quotients provided a prediction of solvent-independent equilibrium constants. However, this strategy did not achieve satisfactory estimations of initial rates in solvents of higher polarity. The lack of compliance with some assumptions of this methodology could be confirmed through molecular dynamics calculations i.e. independent solvation energies and lack of solvent interaction with the active site. A novel approach is proposed combining the activity-based kinetic expression and the free binding energy of the solvent with the active site to predict kinetics upon solvent change. Di-isopropyl ether generated a strong interaction with the enzyme´s active site, which was detrimental to kinetics. On the other hand, toluene or limonene gave moderate interaction with the active site rendering improved catalytic yield compared with less polar solvents, a finding sharpened when peroctanoic acid was produced.
Vitamin D3 supplementation in COVID-19 patients with cardiovascular disease and gut dysbiosis
Vitamin D3 supplementation in COVID-19 patients with cardiovascular disease and gut dysbiosis
Sanz, R. L.; García, F.; Gutierrez, A.; García Menéndez, Sebastián Marcelo Manuel; Inserra, F.; Ferder, L.; Manucha, Walter Ariel Fernando
Background: The COVID-19 pandemic has highlighted the vulnerability of particular patient groups to SARS-CoV-2 infection, including those with cardiovascular diseases, hypertension, and intestinal dysbiosis. COVID-19 affects the gut, suggesting diet and vitamin D3 supplementation may affect disease progression. Aims: To evaluate levels of Ang II and Ang-(1-7), cytokine profile, and gut microbiota status in patients hospitalized for mild COVID-19 with a history of cardiovascular disease and treated with daily doses of vitamin D3. Methods: We recruited 50 adult patients and accessed pathophysiology study 22, randomized to daily oral doses of 10,000 IU vitamin D3 (n=11) or placebo (n=11). Plasma levels of Ang II and Ang-(1-7) were determined by radioimmunoassay, TMA and TMAO were measured by liquid chromatography and interleukins (ILs) 6, 8, 10 and TNF-α by ELISA. Results: The Ang-(1-7)/Ang II ratio, as an indirect measure of ACE2 enzymatic activity, increased in the vitamin D3 group (24±5 pg/mL vs 4.66±2 pg/mL, p<0.01). Also, in the vitamin D3-treated, there was a significant decline in inflammatory ILs and an increase in protective markers, such as a substantial reduction in TMAO (5±2 µmoles/dL vs 60±10 µmoles/dL, p<0.01). In addition, treated patients experienced less severity of infection, required less intensive care, had fewer days of hospitalization, and a reduced mortality rate. Additionally, improvements in markers of cardiovascular function were seen in the vitamin D3 group, including a tendency for reductions in blood pressure in hypertensive patients. Conclusions: Vitamin D3 supplementation in patients with COVID-19 and specific conditions is associated with a more favourable prognosis, suggesting therapeutic potential in patients with comorbidities such as cardiovascular disease and gut dysbiosis.
De las canteras al desarrollo sostenible: Visión actual del potencial geoeconómico de la minería en Entre Ríos, Argentina
De las canteras al desarrollo sostenible: Visión actual del potencial geoeconómico de la minería en Entre Ríos, Argentina; From quarries to sustainable development: Current vision of the geoeconomic potential of mining in Entre Ríos, Argentina
Pedersen, Oscar Ariel; Romero, María Isabel; Thalmeier, Maria Belen; Brunetto, Ernesto
El presente trabajo aborda la necesidad imperativa de realizar un análisis geoeconómico exhaustivo de los recursos minerales en la provincia de Entre Ríos, Argentina. Su finalidad es impulsar un desarrollo minero que sea económicamente viable, ambientalmente respetuoso y socialmente justo. Mediante una metodología detallada que combina análisis geológicos enmarcados en modelos predictivos basados en investigación científica actualizada, evaluaciones ambientales y bases de datos geoespaciales consolidados, se procura atraer inversiones hacia proyectos mineros que contribuyan significativamente al desarrollo económico regional, en un marco de sostenibilidad socio-ambiental.; From quarries to sustainable development: The present work addresses the imperative need for a comprehensive geoeconomic analysis of mineral resources in the province of Entre Ríos, Argentina. Its purpose is to promote mining development that is economically viable, environmentally friendly and socially just. Through a detailed methodology that combines geological analyses framed in predictive models based on updated scientific research, environmental assessments and consolidated geospatial databases, it seeks to attract investments towards mining projects that contribute significantly to regional economic development, within a framework of socio-environmental sustainability.
Prevalence of congenital anomalies and prenatal diagnosis by birth institution (public vs. non-public): indicators of inequality in access to elective termination of pregnancy for fetal anomalies
Prevalence of congenital anomalies and prenatal diagnosis by birth institution (public vs. non-public): indicators of inequality in access to elective termination of pregnancy for fetal anomalies
Brun, Paloma Laura; Groisman, Boris; Bidondo, Maria Paz; Barbero, Pablo Miguel; Trotta, Marianela; Liascovich, Rosa
Congenital anomalies (CA) encompass all morphological or functional alterations originating prenatally and present at birth. The prenatal diagnosis of these anomalies can signifcantly impact the overall health of the pregnant individual and may infuence her decision regarding the continuation of the pregnancy. In contexts where safe pregnancy termination is not guaranteed by the state, it can lead to unsafe procedures with severe consequences. In our research, we analyzed epidemiological information on CA to develop potential indicators of inequity in access to safe abortion prior to the legalization of legal termination of pregnancy in Argentina. We included cases from 13 public hospitals and 9 non-public subsector hospitals, from the period 2013–2020. Two groups of specifc CA were selected: 1) CA capable of being prenatally diagnosed, and 2) CA related to vascular disruptive events. 10/18 of the selected CA capable of being prenatally diagnosed had a signifcantly higher prevalence in public hospitals (anencephaly, encephalocele, spina bifda, microcephaly, hydrocephalus, holoprosencephaly, hydranencephaly, diaphragmatic hernia, gastroschisis, bilateral renal agenesis). Non public hospitals had higher prenatal detection. Birth prevalence of CA related with vascular disruptive events (limb reduction, Moebius syndrome, amniotic band sequence) were signifcantly higher in public hospitals. These results suggest disparities in access to prenatal diagnosis and safe abortion based on socioeconomic status. There was a signifcant gap in access to prenatal diagnosis for CA and possibly to safe elective abortion depending on the type of institution (public vs. non-public).
Mapeo participativo de tecnologías de acceso al agua en el Chaco salteño (noroeste argentino): Avances de una experiencia colaborativa
Mapeo participativo de tecnologías de acceso al agua en el Chaco salteño (noroeste argentino): Avances de una experiencia colaborativa; Participatory mapping of water access technologies in the Chaco of Salta (northwest Argentina): Advances of a collaborative experience; Mapeamento participativo de tecnologias de acesso à água no Chaco de Salta (noroeste da Argentina): Avanços de uma experiência colaborativa
López, Emilce de Las Mercedes; Belmonte, Silvina
Conocer y mostrar espacialmente las distintas formas de acceso al agua en hábitats rurales del Chaco salteño, representa un gran desafío. Para enfrentarlo nos propusimos mapear esas formas de acceso al agua en la zona sistematizar los resultados e incorporarlos a un Sistema de Información Geográfica. La necesidad de este relevamiento surgió a partir de un trabajo colaborativo con las mesas locales de agua (Rivadavia Banda Norte) y de gestión local (La Unión – Rivadavia Banda Sur). Mediante técnicas de cartografía social se identificaron las principales formas de acceso al agua en los diversos parajes, puestos criollos y comunidades originarias de estos municipios. En el espacio provisto por las mesas locales se realizó una priorización que permitió ubicar espacialmente áreas de mayor necesidad de gestión del recurso hídrico. El uso de los sistemas de información geográfica tiene la ventaja de brindar una visión espacial e integral sobre el territorio y en este caso sobre la situación de acceso al agua, de potencial utilidad para la toma de decisiones informadas y la implementación de políticas hídricas efectivas en el Chaco salteño.; Knowing and spatially showing the different forms of access to water in the rural habitats of the Chaco de Salta represents a great challenge. To address this, we proposed to map these forms of access to water in the area, systematize the results and incorporate them into a Geographic Information System. The need for this survey arose from collaborative work with local groundwater (Rivadavia Banda Norte) and local management (La Unión – Rivadavia Banda Sur). Using social mapping techniques, the main forms of access to water in different locations, creole posts and communities originating in these municipalities were identified. In the space provided by the local tables, a prioritization was carried out that made it possible to spatially locate the areas most in need of water resources management. The use of geographic information systems has the advantage of providing a spatial and comprehensive view of the territory and, in this case, the water access situation, potentially useful for making informed decisions and affective water policies in the Chaco de Salta.; Conhecer e mostrar espacialmente as diferentes formas de acesso à águanos habitats rurais do Chaco de Salta representa um grande desafio. Para enfrentá-lo, propusemos mapear essas formas de acesso à água na área, sistematizar os resultados e incorporá-los em um Sistema de Informação Geográfica. A necessidade deste levantamento surgiu do trabalho colaborativo com os lençóis freáticos locais (Rivadavia Banda Norte) e a gestão local (La Unión –Rivadavia Banda Sur). Utilizando técnicas de mapeamento social, foram identificadas as principais formas de acesso à água nos diversos locais, postos crioulos e comunidades originárias desses municípios. No espaço disponibilizado pelas tabelas locais, foi realizada uma priorização que permitiu localizar espacialmente as áreas de maior necessidade de gestão de recursos hídricos. A utilização de sistemas de informação geográfica tem a vantagem de proporcionar uma visão espacial e abrangente do território e, neste caso, da situação de acesso à água, potencialmente útil para a tomada de decisões informadas e a implementação de políticas hídricas eficazes no Chaco de Salta.
Transformaciones y continuidades en la gestión policial de conflictividades durante la pandemia: El caso de Villa María (Córdoba, Argentina)
Transformaciones y continuidades en la gestión policial de conflictividades durante la pandemia: El caso de Villa María (Córdoba, Argentina); Transformations and continuities in the police management of conflicts during the pandemic: The case of Villa María (Córdoba, Argentina)
Goldin, Déborah Judith; Rodríguez, Florencia
Este artículo presenta los resultados de una investigación sobre las transformaciones en las prácticas de policiamiento y control poblacional durante la pandemia por el COVID-19, y los modos en que estos cambios fueron experienciados por los y las policías de Córdoba (Argentina), en el caso del aglomerado Villa María-Villa Nueva durante los años 2020-2021. Aquí abordaremos las conflictividades que fueron relevantes en la localidad durante este período, analizando las transformaciones que se identificaron en las prácticas policiales y sus modos de intervención sobre estos conflictos. Luego, analizaremos las interacciones entre policía y ciudadanía, buscando evidenciar las transformaciones de este vínculo de por sí heterogéneo. Finalmente, indagaremos en las experiencias de los y las policías durante la pandemia, con especial énfasis en su percepción del riesgo y del reconocimiento de su labor, como así también sobre el uso de la fuerza. A partir de este recorrido, consideramos que la pandemia fortaleció el papel de la policía en la gestión poblacional, evidenciando aún más la realización de un abanico de tareas desvinculadas de la persecución del crimen.; This article presents the results of a research on the transformations in policing practices and population control during the COVID-19 pandemic, and the ways in which these changes were experienced by police officers in Córdoba (Argentina), in the case of the Villa María-Villa Nueva urban agglomerate during 2020-2021. Here we will address the conflicts that were relevant in this location during said period, analyzing the transformations that were identified in police practices and their ways of intervening in these conflicts. We analyze the interactions between police and citizens, looking to highlight the transformations of this already heterogeneous relation. Finally, we will inquire into the experiences of the police during the pandemic, with special emphasis on their perception of risk and recognition of their work, as well as on the use of force. On this basis, we consider that the pandemic strengthened the role of the police in population management, further highlighting the performance of a range of tasks unrelated to the prosecution of crime.
Episodicity in accretion-ejection processes associated with IRAS 15398-3359
Episodicity in accretion-ejection processes associated with IRAS 15398-3359
Guzmán Ccolque, Estrella; Fernandez Lopez, Manuel; Vazzano, María Mercedes; de Gregorio, I.; Plunkett, A.; Santamaría Miranda, A.
Context. The protostar IRAS 15398-3359 is associated with a bipolar molecular outflow ejected in an nearly northeast–southwest (NE–SW) direction, which has been extensively studied. Previous episodic accretion events have been suggested by this source. Furthermore, the analysis of the morphology and kinematics of the molecular outflow revealed the presence of four 12CO (2–1) bipolarelliptical shock-like structures identified in both lobes. These structures seem to trace different ejections inclined ∼10◦from each otheron the plane of the sky. This led to the hypothesis that the outflow axis likely precesses and launches material episodically. Aims. Since several authors reached the conclusion of the same episodicity scenario by independent observations, IRAS 15398-3359has become an ideal target to empirically analyze the relationship between accretion and ejection processes.Methods. We analyzed ALMA archive observations in Band 6, revealing the presence of low-velocity (<3.5 km s−1) emission fromthe 12CO (2–1) line to the south and north of the protostar. We studied the morphology and kinematics of the gas; our study seems tosupport the hypothesis of a precessing episodic outflow.Results. The ALMA observations reveal a north–south (N–S) outflow most likely associated with the IRAS 15398-3359 protostellarsystem. This outflow could be older than the well-studied NE–SW outflow. The orientation of the N–S outflow is 50◦–60◦ on the planeof the sky away from that of the NE–SW outflow. We also analyzed the spectral energy distribution of a far away young star andpreliminarily discard it as the driver of the SE outflow remnants. Conclusions. The new observations support the hypothesis of strong episodic accretion-ejection events in IRAS 15398-3359, accompanied by dramatic changes in the orientation of its ejection axis, implying that all the outflows in the region may have been driven bythe same protostar
Páginas
