Obvious manipulations in matching with and without contracts Arribillaga, Roberto Pablo; Pepa Risma, Eliana Beatriz This paper explores many-to-one matching models, both with and without contracts, where doctors’ preferences are private and hospitals’ preferences are public and substitutable. It is known that any stable-dominating mechanism --which is either stable or individually rational and Paretodominates (from the doctors’ perspective) a stable mechanism–, is susceptible to manipulation by doctors. Our study focuses on obvious manipulations and identifies stable-dominating mechanisms that prevent them. Without contracts, we show that any stable-dominating mechanism is not obviously manipulable. However, with contracts, none of these results hold. While we demonstrate that the Doctor-Proposing Deferred Acceptance (DA) Mechanism remains not obviously manipulable, we show that the Hospital-Proposing DA Mechanism and any efficient mechanism that Pareto-dominates the Doctor-Proposing DA Mechanism become (very) obviously manipulable, in the model with contracts.

Fipronil tissue residues and withdrawal period feasibility in laying hens after extra‐label use Cantón, Lucila; Berkovic, Andrea Mariela; Ceballos, Laura; Cantón, Candela; Lanusse, Carlos Edmundo; Alvarez, Luis Ignacio; Moreno Torrejon, Laura Fipronil, a broad-spectrum insecticide, is often used off-label in laying hens to control red mites. This study investigatedfipronil residue levels in hen tissues after simulating common extra-label administrations: in-feed (1 mg kg−1 twice) and transdermal (1 mg kg−1 once). Fipronil residues were quantified by HPLC-MS/MS. Both administrations resulted in quantifiableresidues in edible tissues (muscle, liver, kidney, skin, fat) and feathers for up to 60 days. Fipronil-sulfone, the primary metabolite, was the dominant residue in tissues. Fat accumulated the highest concentrations. In-feed administration led to higheroverall residues in edible tissues, while transdermal application resulted in higher concentrations in feathers. Calculated withdrawal periods, based on established MRLs, ranged from 36 days (muscle, transdermal) to 131 days (fat, transdermal). Theselong withdrawal periods render both administration routes impractical for poultry production. The study highlights the riskof fipronil residues in poultry products and suggests feather/fecal sampling for monitoring illicit use.

Concentración de compuestos organobromados en Delphinus delphis y Lagenodelphis hosei Concentración de compuestos organobromados expresados en ng.g−1 de peso húmedo, determinados en tejido adiposo de Delphinus delphis y Lagenodelphis hosei

Isospectral CR Manifolds with Respect to the Kohn Laplacian Gutierrez, Gerson; Lauret, Emilio Agustin; Rossetti, Juan Pablo We prove that the spectrum of the Kohn Laplacian does not determine the equivalence classes of CR manifolds. We construct pairs of odd-dimensional elliptic manifolds that are not equivalent as CR manifolds but whose Kohn Laplacians have the same spectrum. These manifolds are endowed with the CR structures inherited from the canonical CR structure on the sphere of the same dimension.We provide three different constructions among lens spaces and an additional one among elliptic manifolds with non-cyclic fundamental groups.

Climate change scenarios and the increasing severity of thermal extremes in the pampas region Brendel, Andrea Soledad; Ferrelli, Federico; Piccolo, Maria Cintia This research aimed to analyze the Spatial and Temporal trends and variations of extreme thermal events in the Pampas region (Argentina) over three periods: the present (2009–2023), the near future (2024–2038), and the Far future (2085–2099) under two greenhouse gas concentration scenarios, RCP 4.5 and RCP 8. Across these periods, 14 extreme thermal indices were calculated using maximum and minimum temperature series recorded in situ by 48 meteorological stations. For future projections, we employed two validated climate models: the CCSM4 model (validation index: 0.91) for the humid region and the CNRM-CM5 model (validation index: 0.91) for the central region, selected based on their high performance in representing regional thermal conditions. Results revealed a significant warming trend, with regional maximum temperature increasing by 1.1 °C during 2009–2023, and projections of up to 1.4 °C increase in the Far future under RCP 8.5. A notable Spatial heterogeneity was observed, with Western and central sectors of the Pampas showing more pronounced warming patterns than Eastern coastal areas. Extreme indicators showed pronounced changes: absolute maximum temperature (TXx) increased by 2.5 °C in the present period, with projections of up to 4.9 °C increase by 2085–2099 under RCP 8.5. Warm days (TX90p) increased by 5 days/15 years in the present, with projections of 6.7 days/15 years in the Far future. Concurrently, cold events decreased significantly, with cool days (TX10p) declining by 6 days/15 years in the present and projected to decrease by 7.1 days/15 years in the Far future. This thermal intensification will adversely affect agricultural production, economic development, infrastructure, biodiversity, and public health, heightening the vulnerability of the region’s socio-ecosystems. These findings are critical for developing Spatial management plans and designing climate adaptation and mitigation measures at local and regional scales.

Unraveling Tumor Heterogeneity: Quantitative Insights from Single-cell RNA Sequencing Analysis in Breast Cancer Subtypes Senra, Daniela; Guisoni, Nara Cristina; Diambra, Luis Anibal Background and objectives: Tumors are complex systems characterized by variations across genetic, transcriptomic, phenotypic, and microenvironmental levels. This study introduced a novel framework for quantifying cancer cell heterogeneity using single-cell RNA sequencing data. The framework comprised several scores aimed at uncovering the complexities of key cancer traits, such as metastasis, tumor progression, and recurrence. Methods: This study leveraged publicly available single-cell transcriptomic data from three human breast cancer subtypes: estrogen receptor-positive, human epidermal growth factor receptor 2-positive, and triple-negative. We employed a quantitative approach, analyzing copy number alterations (CNAs), entropy, transcriptomic heterogeneity, and diverse protein-protein interaction networks (PPINs) to explore critical concepts in cancer biology. Results: We found that entropy and PPIN activity related to the cell cycle could distinguish cell clusters with elevated mitotic activity, particularly in aggressive breast cancer subtypes. Additionally, CNA distributions varied across cancer subtypes. We also identified positive correlations between the CNA score, entropy, and the activities of PPINs associated with the cell cycle, as well as those linked to basal and mesenchymal cell lines. Conclusions: This study addresses a gap in the current understanding of breast cancer heterogeneity by presenting a novel quantitative approach that offers deeper insights into tumor biology, surpassing traditional marker-based methods.

Mezclar, predicar, contar cuentos: Tres prácticas letradas recurrentes en la formación docente inicial no universitaria; Mixing, preaching, telling stories: Three recurring literary practices in pre-service teacher education Improvola, Maximiliano Javier Este artículo presenta una parte de los resultados de una investigación concluida recientemente sobre las prácticas de lectura y escritura de un grupo de estudiantes del Profesorado de Educación Primaria de un instituto de formación docente ubicado en el oeste del Área Metropolitana de Buenos Aires. A fin de comprender de qué modos las estudiantes responden a las demandas de lectura de la bibliografía académica que se les plantea desde la institución formadora, combinamos una perspectiva sociocultural de la lengua escrita en uso —proveniente de los Nuevos Estudios de Literacidad— y algunos conceptos de la lingüística sistémico-funcional. A partir del análisis de un corpus integrado mayormente por trabajos escritos de las estudiantes producidos en el marco de cuatro materias del profesorado, identificamos tres prácticas letradas recurrentes: las amalgamas entre autores, las lecturas prescriptivas de la bibliografía académica y las narrativizaciones. Ofrecemos una descripción de ellas y sostenemos que cada una podría ser comprendida como el resultado de una dificultad para captar adecuadamente alguna de las tres dimensiones que, desde el enfoque de la lingüística sistémico-funcional, constituyen el contexto semiótico en el que se solicita a las estudiantes que interpreten los textos académicos y presenten los contenidos de las materias.; This article presents a part of the results of a recently concluded investigation on the literacy practices of a group of students of a Teacher Training College located in the west of the Metropolitan Area of Buenos Aires. In order to understand how these students respond to the reading requirements of academic bibliography that are posed to them in the teacher training program, we combine a sociocultural approach to literacy adopted from the New Literacy Studies with some concepts of systemic functional linguistics. Based on the analysis of a corpus made up mainly of written works produced by the students in four undergraduate subjects, we identified three recurrent literary practices: amalgamations between authors, prescriptive interpretations of academic bibliography, and narrativizations. We offer a description of them and maintain that each one could be understood as the result of a difficulty in adequately grasping one of the three dimensions that, according to systemic functional linguistics, constitute the semiotic context in which students are asked to construe academic texts and present the contents of the courses.

Prosodic Reading in Students with Specific Comprehension Difficulties Roldán, Luis Ángel; Arnés, Victoria; Fernández, Valentina Nahir; Zabaleta, Verónica This study explores the expressive reading skills of Spanish-speaking students experiencing challenges in reading comprehension during the first year of secondary school in Argentina (grade 7). Initially, a cohort of 187 students was examined, leading to the formation of two groups: 27 students with specific comprehension difficulties (SCD) and 27 with proficient comprehension. The groups were matched in terms of decoding skills. Students were tested with a task requiring the computation of punctuation marks and an analytical prosodic reading scale that assesses various parameters such as volume, intonation, pauses, phrasing, and quality. Notably, statistically significant differences emerged between the two groups across all measures. Moreover, robust correlations were identified between expressive reading measures and text comprehension in students with SCD. A logistic regression analysis pinpointed phrasing as the sole significant predictor of group classification. These results underscore the pivotal role of prosodic reading in text comprehension.

Considering land use complexity and overlap is critical for sustainability planning Pratzer, Marie; Maillard, Oswaldo; Baldi, Germán; Baumann, Matthias; Burton, Jamie; Fernandez, Pedro; Levers, Christian; Meyfroidt, Patrick; Tasquer, Macarena; Vallejos, María; Kuemmerle, Tobias Land use is both a driver and a lever to address sustainability challenges like biodiversity loss, climatechange, and food security. Yet, it is often oversimplified in sustainability planning, ignoring the diversity ofactors or the multiple claims on land. We developed an approach to capture the complex and contested nature of land use by mapping it as social-ecological systems that can overlap in space. Demonstrating ourapproach for the Dry Chaco and Chiquitano forests in South America revealed three main insights. First,we mapped actors that are typically overlooked, such as forest-dwelling smallholders. Second, substantialland use overlap, particularly between smallholders and agribusinesses, signals land competition that risksmarginalizing smallholders. Third, our maps showed conservation areas overlapping with other land systems, highlighting opportunities for co-benefits but also competition. Overall, our transferable approach captures land use complexity and visualizes often overlooked actors, thereby potentially contributing to morejust and effective sustainability planning.

First repor t of the interac tion between the toad Melanophryniscus nigricans and the leech Helobdella cordobensis in the Tandilia Mountains Tejedor, Facundo; Trofino Falasco, Clara; Cortelezzi, Agustina; Gullo, Bettina; Gárgano, Lucía; Santiago, Manuela; Berkunsky, Igor Melanophryniscus nigricans is an endangered endemic anuran species restricted to the TandiliaMountains in Argentina. We report for the first time the interaction between this toad speciesand the leech Helobdella cordobensis. We observed the interaction in a temporary pond at the“Sierra del Tigre” Natural Reserve during a breeding event of M. nigricans on February 7th, 2024.A leech was found attached to the belly of a toad and removed manually with no evidence ofinjury in the amphibian, suggesting a case of phoresis instead of parasitism. This report is alsothe first documented phoretic interaction between H. cordobensis and anurans from Argentina.

Causality by Vote: Aggregating Evidence on Causal Relations in Economic Growth Processes de Mier, Manuel; Delbianco, Fernando Andrés; Tohmé, Fernando Abel In this paper, we investigate the performance of fivecausality-detection methods and the aggregation of their resultswhen considering multiple units in a panel data setting. We employvoting rules as an aggregation procedure to determine which causalpaths are identified for the sample population. Using both simu-lated and real-world panel data, we show the performance of thesemethods in detecting the correct causal paths by comparing themto a benchmark that represents a standard growth model as theground truth.

“Segundo Censo de la República Argentina” del año 1895" Terriotrios Naci Neuquen y Rio Negro - paginas 658 “Cuadro VII a.” - 659 “Cuadro VII a.”- 661 “Cuadro VII b.” “Segundo Censo de la República Argentina” del año 1895, Página 658 “Cuadro VII a.” “Población por nacionalidad y sexo” Población que corresponde a los países americanos que corresponde a los territorios Nacionales del Chaco, territorio nacional de La Pampa y territorio nacional de Neuquén, Página 659 “Cuadro VII a.” “Población por nacionalidad y sexo” Población que corresponde a los países americanos que corresponde a los territorios Nacionales de Río Negro, territorio nacional de Chubut, territorio nacional de Santa Cruz y territorio nacional de Tierra del Fuego. Página 661 “Cuadro VII b.” “Población por nacionalidad y sexo” Población que corresponde a los países europeos que corresponde a los territorios Nacionales de Neuquén, de Río Negro, de Chubut y de Tierra del Fuego. Los datos de estos cuadros resultan de gran relevancia para poder conocer, a partir de una fuente de información documental, la composición de la población de los territorios nacionales de Rio Negro y Neuquén (área de investigación en especial la zona cordillerana) por aquel entonces y el peso de la población argentina, chilena y europea. Adquiere doblemente importancia como fuente de información ya que existen muy pocas fuentes documentales de aquel entonces. Las cuadros se presentan en publicaciones a modo de soporte documental (y cuantitativo) de la información analizada cualitativamente.

Quercetin-loaded magnetic nanoparticles: a promising tool for antitumor treatment in human breast cancer cells Tiburzi, Silvina Mabel; Lezcano, Virginia Alicia; Principe, Gabriel; Montiel Schneider, María Gabriela; Miravalles, Alicia Beatriz; Lassalle, Verónica Leticia; Bruzzone, Ariana; González Pardo, María Verónica Quercetin (QUE) is a phytoestrogen with known antitumor properties; however, its hydrophobic nature and low bioavailability limit its efficacy as an anticancer drug. To address this, we explored loading QUE onto a non-toxic nanocarrier. This study focused on the biological activity of magnetic iron oxide nanoparticles coated with polyethylene glycol (MAG@PEG) loaded with QUE (MAG@PEG@QUE) in MCF-7 cells. The MAG@PEG nanosystem was synthesised using a hydrothermal method, and QUE was incorporated by adding an alcoholic solution of QUE to an aqueous dispersion of MAG@PEG. QUE incorporation was confirmed qualitatively by FTIR spectroscopy and quantitatively through UV–visible spectroscopy. Cytotoxicity studies showed that MAG@PEG@QUE, at a concentration equivalent to the half-maximal inhibitory concentration (IC50) of free QUE, significantly reduced cell proliferation and viability while increasing apoptosis. MCF-7 cells treated with MAG@PEG@QUE also displayed actin cytoskeleton alterations typical of apoptotic cells. Transmission electron microscopy revealed clusters of magnetic nanoparticles within cellular vesicles. Targeted delivery of these nanoparticles was achieved using a static magnetic field, leading to high intracellular accumulation and selective cell death in targeted areas, without affecting adjacent cells. In conclusion, MAG@PEG@QUE shows comparable antitumor effects to free QUE and has the potential to enhance QUE’s bioavailability and targeted delivery for breast cancer treatment

Chitin Polymer Transformation Driven by Particulate Matter and Biofilm Interaction in a Disturbed Estuarine Environment Biancalana, Florencia; Forero Lopez, Ana Deisy; Fernandez Severini, Melisa Daiana; Brugnoni, Lorena Inés; Bianchinotti, Maria Virginia; Rimondino, Guido Noé; Vitale, Alejandro José Chitin is critical in carbon and nitrogen recycling, facilitates pollutant adsorption and serves as a substrate for potentially pathogenic microorganisms. This study evaluated its structural, chemical, and microbiological transformations in a polluted environment. An experiment was conducted in the Bahía Blanca Estuary, using chitin in devices attached to a buoy, where samples were collected after 21 and 36 days. X-Ray Diffraction revealed reduced crystallinity over time, with diminished intensity and sharpness of characteristic peaks. Fourier Transform Infrared Spectroscopy detected spectral changes after 36 days, including reduced amide I and II peaks sharpness, indicating partial degradation, via hydrolytic and oxidative processes. Hydroxyl and phosphate groups potentially linked to biofilm formation were also identified. Scanning electron microscopy revealed gradual surface deterioration with cracks and pores and the accumulation of organic and inorganic aggregates, including diatoms. Energy Dispersive X-ray confirmed the presence of heavy metals including molybdenum and iron, likely associated with suspended particulate matter adhering to chitin surface. Fungal and coliform counts increased significantly after 36 days, while heterotrophic bacteria levels remained constant. Vibrio spp. was also detected. Overall, this study underscores chitin´s dual role in biogeochemical processes and environmental applications. As a key component in biodegradation, biofilms facilitate its transformation, highlighting its function as a heavy metal chelating agent and a carbon and nitrogen source. Additionally, the findings suggest the potential of chitin for water treatment applications, where its interactions with biological and environmental factors could be leveraged, providing valuable scientific insights at local and global scales.

Morphology, development and ecological implications of the dentition of Bajadasaurus pronuspinax Garderes, Juan Pablo The associated preservation between dentitions and dentigerous elements is crucial for understanding diverse biological features. Notwithstanding, their fossil record in Sauropoda is relatively seldom, compared to other skeletal elements. Here, the first partially complete dentition including upper and lower teeth in Dicraeosauridae is described, based on Bajadasaurus pronuspinax. This dentition lacks only one upper and two lower functional teeth. The dentigerous elements preserved replacement teeth, which reduce in length and number caudally. Tooth formation times and rates vary within the different elements, with a total mean replacement time of 40.7 days. The functional dentition shows three caudally directed patterns: reduction in size, reduction in curvature, and reduction in the occurrence of wear facets. The functional teeth number mirrors in the occlusal and sagittal planes. The replacement teeth count in Bajadasaurus is lower than the same for other diplodocoids. In this taxon, the tooth-replacement process fits the Zahnreihen with a Z-space-of-two model on the lower dentition, but this model results in a chaotic arrangement of the developmental pattern dorsally, probably due to a replacement mechanism of the whole upper dentition similar to Dicraeosaurus and Apatosaurus. Overall, the dental traits of Bajadasaurus suggest a plausible low-level specialist-feeding ecological niche for this taxon.

Tecnologías de modificación corporal y personas travestis y trans en Argentina: un estudio cuantitativo sobre desigualdades en el uso y acceso; Body modification technologies and transvestite and trans people in Argentina: A quantitative study on inequalities in use and access Farji Neer, Anahí; Dellacasa, María Alejandra; Sustas, Sebastián Ezequiel; Antoniucci, Melina Beatriz; Rustoyburu, Cecilia Alejandra; Noceti, Clara Inés; Mateo, Natacha; Roca, Alejandra Rosario La salud colectiva ha aportado perspectivas analíticas de gran riqueza para comprender la determinación social de la salud y cómo las dinámicas de desigualdad, inequidad e iniquidad son productoras de padecimientos, enfermedades, morbilidad y mortalidad. Desde esta mirada, en este trabajo se identifican y analizan modalidades de apropiación y uso de distintas hormonas e intervenciones de modificación corporal de la población travesti y trans en Argentina, con el propósito de visibilizar las situaciones de vulnerabilidad que puedan estar implicadas en estas prácticas, tanto aquellas realizadas fuera del sistema de salud como las que tuvieron acompañamiento profesional en una institución. Se adoptó una estrategia metodológica cuantitativa, con un diseño descriptivo, observacional y de corte transversal. En 2023, se realizó un relevamiento a través de un cuestionario a nivel federal a personas travestis y trans mayores de 16 años (n=1.196). Los datos analizados dan cuenta de procesos de vulnerabilidad que no se extienden de manera homogénea en toda la población y que responden a desigualdades en salud.; Collective health has provided valuable analytical perspectives for understanding the social determinants of health and how dynamics of inequality, inequity, and injustice contribute to suffering, disease, morbidity, and mortality. From this perspective, this study identifies and analyzes the ways in which transvestite and trans people in Argentina appropriate and use different hormones and body modification interventions, aiming to highlight the vulnerabilities associated with these practices, both those performed outside the healthcare system and those carried out with professional support in an institution. A quantitative methodological strategy was adopted, with a descriptive, observational, and cross-sectional design. In 2023, a nationwide survey was conducted using a questionnaire targeting transvestite and trans people aged 16 and older (n=1,196). The analyzed data reveal vulnerability processes that do not extend uniformly across the entire population and are linked to health inequalities.

Late Miocene expansion of grasslands in northwest Argentina linked to shifting hydroclimate: A complex interaction among tectonics, climate, and ecology Azmi, Iffat; Hyland, Ethan; Cotton, Jennifer; Ghosh, Adit; Raigemborn, María Sol; Tineo, David; Hauswirth, Scott; Insel, Nadja Factors driving the late Miocene expansion of C4 grasses remain widely debated. Here, we explored the role of climate and fire in controlling the abundance of C4 vegetation in the Angastaco Basin (Palo Pintado area) and La Viña Basin, NW Argentina, during the late Miocene (ca. 14−5.33 Ma). From paleosol horizons, we reconstructed paleoclimate and paleovegetation conditions using phytolith assemblages, geochemical and isotopic proxies, and polycyclic aromatic hydrocarbons (PAHs) to determine fire input. Our paleoclimate reconstructions suggest a stable mean annual temperature (MAT) of ∼10 °C and a gradual decline in mean annual precipitation (MAP) from 1100 mm yr−1 to 850 mm yr−1. Paleovegetation reconstructions from carbon isotopic composition and phytolith assemblages show a maximum of ∼15% C4 vegetation by 6 Ma. No significant increases in fire occurrence or establishment of fire feedbacks were identified from the PAH data. Though low in abundance (∼3% on average), our data identified the presence of C4 grass by the late Miocene. The lack of significant C4 expansion in this region was likely controlled by the changing hydroclimatic conditions associated with the Andes mountain range—increasing aridity and elevation constraints along with the lack of a fire feedback might have limited the distribution of C4 vegetation.

Datos crudos de secuenciación masiva del gen 16S-ARNr obtenidos a partir de muestras ambientales durante un proceso de oxidación-bioestímulo-fitorremediación aplicado a barros petroquímicos The generation of oily sludges with a high hydrocarbon content is an unavoidable problem for the petrochemical industry. The goal of this project is to study microbial community structure of oily sludges from petroleum refineries, treated with chemical (e.g. oxidation) and/or biological remediation strategies (e.g. composting, phytoremediation) throughout the full process. A deep understanding of microbial community dynamics during the remediation process provides the support for a better design of sustainable management strategies to treat oily sludges.

Censo de puestos por productos en la Manka Fiesta, en las ediciones de 2018 a 2024 Censo realizado en días domingos durante la Manka Fiesta, feria anual realizada en La Quiaca entre el 2do y el 3er domingo de cada octubre. Se censaron todos los puestos según su tipo de producto mayoritario. En cada columna (toma específica) se indica el día del relevamiento, desde 2018 a 2024, excepto 2020, y quién realizó el censo

Datos crudos de secuenciación masiva del gen 16S-ARNr obtenidos a partir de muestras de un suelo contaminado con PAH de manera aguda e inoculado con distintos consorcios bacterianos The goal of this project is to compare bioaugmentation with different inocula on an artificially hydrocarbon contaminated soil and understand how it impacts on contaminant degradation and bacterial community diversity.