Cholesterol free niosome production by microfluidics: Comparative with other conventional methods Machado, Noelia Daiana; García Manrique, Pablo; Fernández, Mariana Adela; Blanco López, Maria Carmen; Matos, María; Gutiérrez, Gemma The extended use of niosomes in food, cosmetic and pharmaceutical industries demands novel preparation processes which could enhance nanovesicles production with controlled size and size distribution. Microfluidics (MF) are a novel promising set of preparation methods for this purpose. Studies comparing methods for niosome preparation are still scarce. In this work, niosomes using MF were produced and the effect of membrane compounds concentration and the relation between organic and aqueous ratio (flow rate ratio, FRR) on the resulting mean size and size distribution were studied. Two different cholesterol free formulations were tested using Tween® 80 and Span® 80 in presence and absence of 1-dodecanol as membrane stabilizer. The effect of FRR showed to be the key parameter in niosomes production, being more critical than membrane compounds concentration and the vesicle membrane composition. Additionally, the same formulations were also produced by two conventional methods, thin film hydration (TFH) and ethanol injection (EI), and results were compared. The size of the niosomes obtained by MF was smaller and more homogeneous than those achieved by TFH and similar to EI. Therefore, MF is confirmed as a novel technology that can facilitate the development and optimization of new nanodelivery systems with controlled size and polydispersity, two essential parameters for successful biotechnological applications.

Evaluation of cellular safety and the chemical composition of the peanut (Arachis hypogaea L.) ethanolic extracts Menis Candela, Florencia; Giordano, Walter Fabian; Quiroga, Patricia Liliana; Escobar, Franco Matias; Mañas, Fernando Javier; Roma, Dardo Andrés; Larrauri, Mariana; Comini, Laura Raquel; Soria, Elio Andres; Sabini, Maria Carola Arachis hypogaea L. (Leguminosae) is distributed in tropical and subtropical areas. Peanut has high nutritional and commercial value. Scientific research showed that peanut has biological properties such as anticancer, antioxidant, antiinflammatory. However, it is necessary to know if consumption of peanut, either as food or as a phytopharmaceutical implies a health risk. The aim was to evaluate cytotoxicity and genotoxicity of ethanolic extracts from A. hypogaea. Also, chemical characterization of these extracts was performed. Cytotoxicity was evaluated by MTT and Neutral Red Uptake (NRU) assays on Vero cells. Genotoxicity was studied by Micronuclei and comet assays on Balb/C mice. Qualitative and quantitative chemical analysis of extracts were performed. Results showed that extracts have low cytotoxicity. Tegument ethanolic extract (TEE) and Seed ethanolic extract (SEE) were not genotoxic. The treatments with TEE at 250 mg/kg and SEE at 2000 mg/kg revealed (highest concentrations evaluated) some toxicity on blood marrow cells of mice. Chemical characterization indicated that TEE had 74.33 1.10 mg GAE/g of dried extract and SEE had 15.05 0.06 mg GAE/g of dried extract of total phenolic content. Also, proanthocyanidins (O.D. at 550 nm 1.39 0.15) and caffeic acid (2.46%) were identified in TEE. While, linoleic acid (58.84%) oleic acid (11.31%) and palmitic acid (8.37%) were major compounds of SEE. In conclusion, peanut consumption is safe at concentrations recommended for healthy uses, such as nutrition, and phytomedicine.

Intervención extensionista en salud cardiovascular en un hospital escuela Oberto, María Georgina; Perovic, Nilda Raquel; Celi, Alejandra; Marchiori, Georgina Noel; Flores, David; Carrizo, Lidia Noemi; Defagó, María Daniela El acercamiento a la comunidad a través de la extensión, junto a la investigación y la docencia constituyen la misión de las universidades, y es relevante como una instancia de aproximación de los estudiantes a la realidad. El objetivo de la intervención fue generar un espacio de sensibilización sobre la importancia de adquirir hábitos saludables para el cuidado del corazón y el bienestar, y que estos contribuyan a la prevención de enfermedades cardiovasculares. El ámbito de desarrollo fue el Hospital Nacional de Clínicas, mediante la instalación de un stand en el interior de la institución. Se intercambiaron experiencias y conocimientos con quienes transitaron por dicho espacio. Antes del encuentro, el equipo extensionista, participó de dos talleres de formación en comunicación y consejería en salud cardiovascular. Se entregaron 500 imanes con mensajes saludables para promover la salud cardiovascular. A partir de los testimonios de los estudiantes, se pudo valorar la importancia de sus aprendizajes mediante esta práctica experiencial que propició su acercamiento a realidades concretas en el territorio, nuevas formas de razonamiento, interacción con diferentes actores sociales y sus conocimientos tradicionales, conocer nuevos escenarios, construir nuevos conocimientos, y relacionar el conocimiento con la acción en situaciones reales.

Probabilistic Analysis of Impacts on Distribution Networks due to the Connection of Diverse Models of Plug-in Electric Vehicles Coria Pantano, Gustavo Ezequiel; Penizzotto Bacha, Franco Victor; Romero Quete, Andrés Arturo This work analyzes impacts on distribution networks produced by the connection ofdiverse types of Plug-in Electric Vehicles (PEVs), into a probabilistic framework. Some of the uncertainty sources are related with technical parameters of PEVs. Therefore, a review of PEVs currently available in the market is reported. Other uncertain parameters are related with the behavior of the PEV owners, for instance, the arrival and departure times to home, and the state of charge of the PEV when it is plugged to the grid. These parameters are modeled by using probability density functions, to thengenerate random numbers and perform Monte Carlo simulations. Each Monte Carlo simulation corresponds to the calculation of a power-flow in the analyzed network. The proposed methodology is tested on the IEEE 33-bus test distribution network, with the purpose of quantifying the influence of diversity of PEVs. The analysis is performed, specifically, for identify those transformers and lines that could be overloaded. Two scenarios of PEV penetration by 2025 and 2030 were assessed, i.e., considering that 10% and 30% of the residential customers will have at least one PEV, respectively. Obtained results reveal the importance of considering diversity of PEV model to conduct in a suitable manner this type of studies. The proposed methodology is expected to be useful for network planning expansion and to support the design of time of use tariffs.

Exceptional cases of textile mineralization in archaeological metallic objects from Santiago del Estero's lowlands (Argentina) Angiorama, Carlos Ignacio; Lopez Campeny, Sara Maria Luisa; Taboada, Constanza Here, we present and discuss the results obtained from a series of techno-morphological and compositional analyses performed on two objects from the collection of the “Emilio and Duncan Wagner” Anthropology and Natural Sciences Museum, currently deposited in the Cultural Heritage Interpretation and Conservation Centre of Santiago del Estero, Argentina. These objects are fragments of metallic bracelets that have preserved textile evidence on their surfaces, or “fibre or textile pseudomorphs”. The pieces, recovered during early 20th century archaeological collecting activity, were found in Santiago del Estero's lowlands and conceivably originate from colonial funerary contexts (post 1543 CE). Our analysis indicates that the fragments correspond to two different bracelets, and that they were made with brass, an alloy of copper and zinc that was not used in northwest Argentina in pre-Hispanic times. The associated textile fragments were made with cotton and present great technological similarities. The sum of evidence indicates that metallic objects were obtained from the Andean region through different modes of appropriation and then incorporated into local daily and funerary practices. Yet, the results of textile analysis reveal no evidence suggesting production according to Hispanic traditions. This paper provides new data on the characterization of archaeological materials from museum collections, offers novel information regarding alteration processes linked to ancient textiles and metals, and constitutes a contribution to the assessment of hypotheses on local practices and processes from Inca and colonial times within the studied region.

A review of euryoryzomys legatus (Rodentia, sigmodontinae): Morphological redescription, cytogenetics, and molecular phylogeny Guilardi, Mariana D.; Jayat, Jorge Pablo; Weksler, Marcelo; Patton, James L.; Ortiz, Pablo Edmundo; Almeida, Keila; De Silva, Maria José The taxonomic history of Euryoryzomys legatus has been complex and controversial, being either included in the synonymy of other oryzomyine species or considered as a valid species, as in the most recent review of the genus. Previous phylogenetic analyses segregated E. legatus from E. russatus, its putative senior synonym, but recovered it nested within E. nitidus. A general lack of authoritative evaluation of morphological attributes, details of the chromosome complement, or other data types has hampered the ability to choose among alternative taxonomic hypotheses, and thus reach a general consensus for the status of the taxon. Herein we revisit the status of E. legatus using an integrated approach that includes: (1) a morphological review, especially centered on specimens from northwestern Argentina not examined previously, (2) comparative cytogenetics, and (3) phylogenetic reconstruction, using mitochondrial genes. Euryoryzomys legatus is morphologically and phylogenetically distinct from all other species-level taxa in the genus, but its 2n=80, FN=86 karyotype is shared with E. emmonsae, E. nitidus, and E. russatus. Several morphological and morphometric characters distinguish E. legatus from other species of Euryoryzomys, and we provide an amended diagnosis for the species. Morphological characters useful in distinguishing E. legatus from E. nitidus, its sister taxon following molecular analyses, include: larger overall size, dorsal fur with a strong yellowish brown to orange brown tinge, flanks and cheeks with an orange lateral line, ventral color grayish-white with pure white hairs present only on the chin, presence of a thin blackish eye-ring, tail bicolored, presence of an alisphenoid strut and a well-developed temporal and lambdoid crests in the skull, and a labial cingulum on M3. Molecular phylogenetic analyses recovered E. legatus as a monophyletic group with high support nested within a paraphyletic E. nitidus; genetic distances segregated members of both species, except for an exemplar of E. nitidus. Our integrated analyses reinforce E. legatus as a full species, but highlight that E. macconnelli, E. emmonsae, and E. nitidus each may be a species complex and worthy of systematic attention. Finally, we also evaluated the chromosome evolution of the genus within a phylogenetic context.

Towards a System of Distributional National Accounts: Methods and Global Inequality Estimates from WID.world Gonzalez Alvaredo, Facundo; Chancel, Lucas; Piketty, Thomas; Saez, Emmanuel; Zucman, Gabriel This paper briefly presents the methodology of Distributional National Accounts (DINA), which distributes total national income and total wealth among all individual residents. With DINA, we can estimate inequality statistics and growth by income and wealth groups that are consistent with aggregate growth from National Accounts. This methodology has been recently applied to a number of countries, and the data produced are available from WID. world. The paper summarizes the initial empirical findings. We observe rising top income and wealth shares in nearly all countries in recent decades, but the magnitude of the increase varies substantially, thereby suggesting that different country‑specific institutions and policies matter. We combine countries’ statistics to estimate global inequality since 1980. Global inequality has increased since 1980 in spite of the catching up of large emerging countries like China and India. This has been driven by the income growth of top world earners.

Minimization of the adverse environmental effects of discarded onions by avoiding disposal through dehydration and food-use Fabani, Maria Paula; Román Barón, María Celia; Rodriguez, Rosa Ana; Mazza, German Delfor Onion is a commonly used vegetable in the Cuyo Region, Argentina, and important in the world global vegetable production ranking. Production levels often exceed immediate markets of fresh sale, and excesses, although still edible, are currently discarded (mostly incinerated and disposed in landfill, creating numerous environmental hazards). To minimize these adverse environmental problems, this research investigates upgrading the discarded products by dehydration, hence guaranteeing their ultimate food-use. The dehydration process of discarded onion cv. Crioula Roxa was hence studied at 60 and 70 °C, temperatures selected to maintain the main physicochemical characteristics of the onions, while also creating optimum heat and mass transfer coefficients while significantly reducing the energy consumption and CO2 emissions. When using an electrically-heated convective dryer, the Specific Energy Consumption (SEC) values and the CO2 emissions during dehydration at 70 °C are 738.89 kWh.kg−1 and 264.74 kg of CO2 kg−1, respectively. These values are only 41.61 kWh.kg−1 and 2–4 kg of CO2 kg−1 if a solar dryer is applied. The thermal diffusivities were 1.86✕10−10 m2 s−1 (dehydration) and 1.08✕10−10 m2 s−1 (rehydration), showing a weak effect of the dehydration process on the solid structure and properties.

Calculadoras de riesgo cardiovascular en personas viviendo con el virus de la inmunodeficiencia humana; Cardiovascular risk calculators for people living with human immunodeficiency virus Grand, M.; Diaz, Alberto Alejandro; Bia, D. El creciente acceso y la alta eficacia del tratamiento antirretroviral han permitido que las personas que viven con el virus de la inmunodeficiencia humana alcancen una expectativa de vida semejante a la población general. Sin embargo, esta expectativa puede verse afectada por el aumento del riesgo de enfermedad cardiovascular en estos pacientes. Este riesgo es multifactorial, involucrando la elevada prevalencia de factores de riesgo cardiovascular tradicionales, el desarrollo de un estado proinflamatorio relacionado con la infección crónica y el uso de fármacos antirretrovirales con un perfil metabólico adverso. En la práctica clínica diaria disponemos de diferentes tablas y/o calculadoras para estimar el riesgo cardiovascular y orientar en la toma de decisiones médicas. La mayoría de estos surgen de estudios poblacionales en pacientes sin infección por el virus de la inmunodeficiencia humana. El objetivo de esta revisión es describir algunos determinantes de la enfermedad cardiovascular en personas que viven con el virus de la inmunodeficiencia humana, y la utilidad y aplicación de las calculadoras de riesgo cardiovascular en dichas personas.; The increasing access and efficacy of antiretroviral therapy has allowed people living with human immuno deficiency virus to achieve a life expectancy similar to that of the general population. However, this goal may be affected by the increased risk of cardiovascular disease in this group. This risk is multifactorial, involving the high prevalence of traditional risk factors, the development of a pro-inflammatory state related to chronic infection, and the use of anti-retroviral drugs with an adverse metabolic profile. In daily practice, in order to estimate this risk and guide medical decision-making, different calculators are available. These are based on data from population cohorts, many of them from human immunodeficiency virus negative subjects. The main aim of this review is to describe the epidemiology of cardiovascular disease in people living with human immunodeficiency virus, the available risk calculators and their use.

Impact of age at first calving on performance and economics in commercial dairy herds in Argentina Turiello, María Paula; Vissio, Claudina; Heinrichs, Arlyn Jud; Issaly, Liliana Cristina; Larriestra, Alejandro Jose Dairy herd efficiency depends on an adequate replacement program, and one of the main management factors affecting the replacement cost is age at first calving (AFC). The primary objective of this study was to evaluate the impact of AFC on performance and economic results in commercial dairy herds in Argentina. A retrospective study was conducted to analyze data from a total of 26,614 first lactation cows from 290 argentinian dairy farms calved for the first time during the calendar year 2016. Milk yield for first lactation cows having at least 5 milk test days was used to analyze production (n=15,181). Records were stratified by AFC into 5 groups: 1) 18–21 mo (n=202), 2) 22-25 mo (n=5,569), 3) 26-29 mo (n=5,579), 4) 30-33 mo (n=2,389), 5) 34-37 mo (n=1,442). The overall median of AFC was 27 mo. Although milk yield at the beginning of the lactation was lower for lower AFC categories, the differences between categories 2, 3, and 4 disappeared by the fourth test day at approximately 113 days in milk. No effect of AFC category was detected for milk fat and protein content and for SCC. Considering AFC categories, cows calving for the first time at 22–25 mo of age needed the shortest period after calving to conceive. The lower income associated with the mild milk losses may be compensated by the cost of more than 80 extra d in the rearing period and the increment in days open estimated for the upper categories.

Franҫoise Perus: la crítica materialista en la “crisis del tiempo”; Franҫoise Perus: materialist criticism in the “crisis of time” Kozel, Gabriel Andrés El artículo aborda la obra de Franҫoise Perus, crítica literaria de origen francés radicada en América Latina desde hace más de medio siglo. Busca ofrecer respuestas a tres interrogantes: 1) cómo convendría periodizar y organizar su obra; 2) cuáles son sus principales aportes teóricos; 3) qué intersecciones cabe perfilar entre tales aportes y el estudio de elaboraciones textuales no ficcionales, como el ensayo de ideas. Los tres interrogantes se inscriben dentro de una pregunta más amplia relativa al procesamiento de la crisis del tiempo (Hartog) por parte de la intelectualidad latinoamericana contemporánea, en la convicción de que en la obra de Perus se encuentra una modulación singularmente lúcida y coherente de esa compleja experiencia.; This article deals with the work of Franҫoise Perus, French literary critic established in Latin America for more than half a century. It seeks to put forward answers to three questions: 1) how should we organize her work in periods; 2) what its main theoretical contributions are; 3) what intersections can be outlined between such contributions and the study of non-fictional textual elaborations, such as the “essay of ideas”. These questions are situated as part of a broader one that pertains to the processing of the “time crisis” (Hartog) by the contemporary Latin American intellectuality. They also stem from the conviction that there is in Perus a singularly lucid and coherent modulation of that complex experience,

Heterologous microsatellite primers are informative for paca (Cuniculus paca), a large rodent with economic and ecological importance Roldán Gallardo, Franco Fabián; Dematteo, Karen; Rinas, Miguel Angel; Argüelles, Carina Francisca Objective: This study was designed to facilitate genetic studies that would allow information on population structure and genetic diversity of natural or captive stocks of paca (Cuniculus paca), a species of ecological and socioeconomic importance, by testing cross-amplification of 20 heterologous microsatellite primer pairs developed for guinea pigs (Cavia porcellus) and capybara (Hydrochoerus hydrochaeris). Results: Those primers that showed the best amplification profile in blood samples were subsequently applied to scats and saliva samples, to evaluate their efficiency. Of the 13 microsatellite pairs that amplified in blood, one-third (32%) were successfully amplified in saliva and scat samples. This initial work demonstrates successful cross-amplification in paca providing a solid and promising foundation for future genetic studies with this species. The ability to quantify genetic diversity using noninvasive samples from free-ranging paca is essential to developing applied management strategies for this large neotropical rodent that is not only a prey favored by wide-ranging carnivores [e.g., jaguar (Panthera onca), puma (Puma concolor)], but is also a species targeted by illegal hunting and wildlife trade.

Las leyes divinas del tiempo y del espacio: Historicismo, política y temporalidad en el discurso del joven Alberdi; The divine laws of time and space: Historicism, politics and temporality in the speech of the young Alberdi Wasserman, Fabio Enrique El trabajo reconstruye y examina la conceptualización de la temporalidad como tiempo histórico que forjaron los jóvenes románticos de la Generación del 37 y, a la vez, analiza cómo influyó en su interpretación del estado sociopolítico y en sus intervenciones en la vida pública rioplatense entre fines de la década de 1830 y comienzos de la de 1840. El foco está puesto en la obra y en la actuación de Juan Bautista Alberdi, dada la importancia y visibilidad que alcanzó en esos años y por haber sido dentro del grupo romántico quien mejor desarrolló esta novedosa concepción del tiempo de cuño historicista.; The paper reconstructs and examines the conceptualization of temporality as historical time developed by the young romantics of the Generation of 37 and, at the same time, analyzes how it influenced their interpretation of the socio-political state and their interventions in Rioplatense public life between the late 1830s and early 1840s. The focus is on the work and performance of Juan Bautista Alberdi, given the importance and visibility he achieved in those years and for having been the one who best developed within the romantics this novel conception of historicist time.

Removal of microcystin-LR and other water pollutants using sand coated with bio-optimized carbon submicron particles: Graphene oxide and reduced graphene oxide Kumar, Pratik; Pérez, José Alberto Espejel; Cledón, Maximiliano; Brar, Satinder Kaur; Duy, Sung Vo; Sauvé, Sébastien; Knystautas, Émile Sand is the most used filter adsorbent material in a drinking water treatment plant (DWTP) or household purpose filters. However, sand poses challenge for the micropollutant removal in presence of metals, natural organic matter, total organic carbon, ammonia and other macro-pollutants. In this study, sand was coated using laboratory-synthesized graphene oxide (GO) and reduced graphene oxide (rGO) to enhance its surface properties in terms of hydrophobicity, roughness and specific surface area (6 times higher for GO/rGO as compared to 5.5 m2/g for sand), that allowed an enhanced adsorption of macro pollutants as well as one target micropollutant: Microcystin-LR (MC-LR). A more electropositive surface than sand (zeta potential: −43.2 mV) in form of iron oxide-coated sand (IOCS or Fe: −21.2 mV) and its combination with GO (FeGO: −13.4 mV) was tested to validate the hypothesis of enhanced MC-LR adsorption due to electrostatic attraction. Two known MC-LR degraders (Arthrobacter ramosus and Bacillus sp.) were screened before bioaugmentation, based on the biofilm forming potential for each coated sand composite. Additionally, the dosage of GO and rGO were bio-optimized before coating them over the sand grains (400 mg/L for GO and 520 mg/L for rGO), to obtain a non-toxic and non-disruptive effect and providing at least 60% cell viability. A highest MC-LR removal of 91% was obtained under biodegradation phase using rGO-coated sand that showed an increase of 47.2% in MC-LR removal when compared to physical adsorption phase. Sand filter (control) showed a maximum MC-LR removal of 54.7%. The highest saturation adsorbent constants of 8.5 mg/kg and 7.4 mg/kg were obtained for GO and rGO-coated sand media, respectively, which was 5–6 times higher than the uncoated sand.

Gender-neutral donor deferral policies: experience in Argentina implementing individual risk-assessment policies Blanco, Sebastian; Carrizo, Luis Horacio; Moyano, Rolando Walter; Mangeaud, Arnaldo; Gallego, Sandra Veronica Background: In Argentina, with the aim of moving to a safe supportive and inclusive National Blood System, in September 2015 the Ministry of Health stipulated that eligibility criteria for blood donation should only take into account the so-called 'risk practices', focusing on a 'gender-neutral' policy. The aim of this study is to demonstrate the impact of such regulation on the prevalence of STI in the population of blood donors in Argentina, through the analysis of the scientific evidence obtained from 174 074 donors from a large central region of the country, focused on a regional Blood Bank for a 6-year period (pre- and post-entry into force of the regulations). Materials and Methods: To analyse the evolution of prevalence rates of STI, two periods of 3 years each were evaluated: The first period (P1) lasted from 16 September 2012 to 15 September 2015 (prior to the entry into force of the law) and the second one (P2) from 16 September 2015 to 15 September 2018 (after the entry into force of the law). Results: A total of 82 838 subjects were enrolled in P1 and 91 236 in P2. The results show a significantly lower prevalence of HCV (P = 0·029), HBV (P = 0·028) and syphilis (P = 0·001) in P2, while no difference was observed for HIV infection (P = 0·60). Conclusion: This study evidenced that the implementation of a 'gender-neutral' policy based on individual risk-assessment deferral criteria maintained the safety of blood supply and decreased the prevalence of STI among blood donors.

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome Pastor, Raul Francisco; Repetto, Marisa Gabriela; Lairion, Fabiana; Lazarowski, Alberto; Merelli, Amalia; Manfredi Carabetti, Zulma; Pastor, Isabel; Pastor, Elena; Iermoli, Laura Valeria; Bavasso, Carlos Amadeo; Iermoli, Roberto Héctor Metabolic Syndrome (MetS) is increasing worldwide regardless of culture, genetic, gender, and geographic differences. While multiple individual risk factors, such as obesity, hypertension, diabetes, and hyperlipidemia, can cause cardiovascular disease (CVD), it is the intercurrence of these risk factors that defines MetS as a cluster that creates an environment for atherosclerosis and other manifestations of CVD. Despite the advances in the knowledge and management of each of the components of MetS, there are two molecular biology processes, chronic inflammation and oxidative stress, which are still underdiagnosed and undertreated. In order to assess the effect of a dietary supplement on chronic inflammation in MetS, we conducted a clinical trial with volunteers receiving a formula composed of resveratrol, piperine and alpha tocopherol (FRAMINTROL®), together with their habitual treatment, for three months. The inflammatory state was evaluated by ultrasensitive C reactive protein (US CRP) and ferritin in plasma, and oxygen consumption and chemiluminescence in neutrophils. The results showed that ferritin decreased by 10% (p < 0.05), US-CRP by 33% (p < 0.0001), oxygen consumption by 55% (p < 0.0001), and spontaneous chemiluminiscence was by 25% (p < 0.005) after treatment. As far as we know, this is the first study showing a chronic inflammation decrease in MetS patients due to the administration of a biopower Resveratrol-piperine and alpha tocopherol dietary supplement together with conventional therapy.

Alteridad, filosofía y creación artística: una mirada bajtiniana; Otherness, philosophy and artistic creation: a Bakhtinian look Wagon, María Elena El problema del Otro es un cuestionamiento relativamente nuevo en el terreno filosófico, pues no forma parte del origen griego de la filosofía occidental sino que se constituye como pregunta filosófica recién en la Modernidad. Este artículo pretende ahondar en la problemática de la alteridad, reflexionando sobre la forma en que dicha temática ha sido abordada por parte de la filosofía occidental. A tal efecto, se hace eco del aporte de Lévinas, quien considera que desde sus orígenes en la filosofía occidental ha primado la ontología por sobre la ética, y, en consecuencia, el concepto por sobre la individualidad. En el acto de conceptualización y objetivación del mundo por parte del Yo se neutraliza la alteridad del Otro y se lo convierte en Mismidad. Ahora bien, no obstante retomar la propuesta lévinasiana, en este trabajo se plantea que la cuestión fundamental que provoca la ausencia del Otro en el discurso filosófico es la falta de conexión entre el plano teórico de la cultura y la esfera práctica de la vida, espacio exclusivo donde se da el encuentro/choque entre el Yo y el Otro. Teniendo en cuenta esto, se deja parcialmente de lado el aporte lévinasiano, para analizar la propuesta filosófica de Mijaíl Bajtín, quien remarca que la gran falencia de la filosofía es no poder establecer un contacto directo entre el ámbito abstracto y universal en el que actúa y la singularidad de la vida práctica del ser humano. La originalidad de este trabajo está dada por la fundamentación de la sentencia lévinasiana por medio de la propuesta teórica de Bajtín.; The problem of the Other is a relatively new questioning in the philosophical field, since it is not part of the Greek origin of Western philosophy, but it is constituted as a philosophical question only in Modernity. This research aims to delve into the problem of otherness, reflecting on the way in which this subject has been addressed by Western philosophy. To this end, he echoes the contribution of Lévinas, who considers that from its origins in western philosophy, ontology has prevailed over ethics, and, consequently, the concept over individuality. In the act of conceptualization and objectification of the world on the part of the Self, the alterity of the Other is neutralized and becomes Mismity. Now, despite taking up the Levinasian proposal, in this work it is stated that the fundamental question that causes the absence of the Other in philosophical discourse is the lack of connection between the theoretical plane of culture and the practical sphere of life, space exclusive where the encounter / clash between the Self and the Other occurs. Taking this into account, the Levinasian contribution is partially set aside, to analyze the philosophical proposal of Mikhail Bakhtin, who remarks that the great flaw of philosophy is not being able to establish direct contact between the abstract and universal sphere in which it operates and the singularity of the practical life of the human being. The originality of this work is given by the foundation of the Levinasian sentence through Bakhtin's theoretical proposal.

SENSEI: Direct-Detection Results on sub-GeV Dark Matter from a New Skipper CCD Barak, Liron; Bloch, Itay M.; Cababie, Mariano Ruben; Cancelo, Gustavo Indalecio; Chaplinsky, Luke; Chierchie, Fernando; Crisler, Michael; Drlica Wagner, Alex; Essig, Rouven; Estrada, Juan; Etzion, Erez; Fernández Moroni, Guillermo; Gift, Daniel; Munagavalasa, Sravan; Orly, Aviv; Rodrigues, Dario; Singal, Aman; Sofo Haro, Miguel Francisco; Stefanazzi, Leandro; Tiffenberg, Javier Sebastian; Uemura, Sho; Volansky, Tomer; Yu, Tien Tien; SENSEI collaboration We present the first direct-detection search for sub-GeV dark matter using a new ∼2-gram high-resistivity Skipper CCD from a dedicated fabrication batch that was optimized for dark matter searches. Using 24 days of data acquired in the MINOS cavern at the Fermi National Accelerator Laboratory, we measure the lowest rates in silicon detectors of events containing one, two, three, or four electrons, and achieve world-leading sensitivity for a large range of sub-GeV dark matter masses. Data taken with different thicknesses of the detector shield suggest a correlation between the rate of high-energy tracks and the rate of single-electron events previously classified as "dark current."We detail key characteristics of the new Skipper CCDs, which augur well for the planned construction of the ∼100-gram SENSEI experiment at SNOLAB.

Wide axial-ratio bandwidth crossed dipole RFID antenna Peruzzi, Victor M.; Masson, Favio Roman; Mandolesi, Pablo Sergio; Perotoni, Marcelo B. A circularly polarised RFID tag antenna with wide axial ratio bandwidth, wide impedance bandwidth and simple tuning network is presented. The antenna, based on the widely used crossed-dipole design, incorporates a novel matching network based on two large L-shaped strips joining the arms of the dipoles to match the impedance. The L-shaped strips create large area loops enabling the antenna to be adapted to the high inductances required for good matching without the currents flowing through them degrading the axial ratio of the antenna. The gain pattern, input impedance and axial ratio (AR) are computed with numerical simulation and measurements, resulting in a 30 MHz bandwidth based on the −3 dB Axial Ratio criterion, which can provide a maximum reading distance of 12.8 m.

Raptor Entanglement with Human Debris at Nests: A Patchy and Species-Specific Problem Mallet, Julieta; Liébana, María Soledad; Santillán, Miguel Ángel; Grande, Juan Manuel Several species of birds, including raptors, add man-made objects, stones, greenplants, skins and dung of animals to build and decorate their nests. However, there is a compromise between the use of new nesting material and the increased risk of nestling mortality due to entanglement or ingestion of debris. Here, we present a compilation of cases of entanglement in raptors and specifically in a very common but poorly studied South American raptor. We observed the decoration in 86 of 95 (90,5%) nests of Southern Caracara (Caracara plancus) in an agricultural area of La Pampa province. Caracaras mainly incorporated agricultural twine in their nests and nestlings sometimes got entangled and died. We found 2 occurrences of entanglement during nine years of study. Decorating the nest, or at least to lean its interior with nylon twine, can impose a relevant death toll to Southern Caracaras, as has been found in other species elsewhere. Extension campaigns to reduce the misuse and the final disposal of debris materials such as baling twine in agricultural landscapes will be required to reduce this anthropic source of mortality in a species that although still common, is apparently reducing its numbers with the expansion of intensive agriculture.