Sindicador de canales de noticias
Asymmetric forest transition driven by the interaction of socioeconomic development and environmental heterogeneity in Central America
Redo, Daniel J.; Grau, Hector Ricardo; Aide, T. Mitchell; Clark, Matthew L.
Forest transitions (FT) have been observed in many developed countries and more recently in the developing world. However, our knowledge of FT from tropical regions is mostly derived from case studies from within a particular country, making it difficult to generalize findings across larger regions. Here we overcome these difficulties by conducting a recent (2001-2010) satellite-based analysis of trends in forest cover across Central America, stratified by biomes, which we related to socioeconomic variables associated with human development. Results show a net decrease of woody vegetation resulting from 12,201 km2 of deforestation of moist forests and 6,825 km2 of regrowth of conifer and dry forests. The Human Development Index was the socioeconomic variable best associated with forest cover change. The least-developed countries, Nicaragua and Guatemala, experienced both rapid deforestation of moist forests and significant recovery of conifer and dry forests. In contrast, the most developed countries, Panama and Costa Rica, had net woody vegetation gain and amore stable forest cover configuration. These results imply a good agreement with FT predictions of forest change in relation to socioeconomic development, but strong asymmetry in rates and directions of change largely dependent upon the biomewhere change is occurring. The FT model should be refined by incorporating ecological and socioeconomic heterogeneity, particularly inmulticountry and regional studies. These asymmetric patterns of forest change should be evaluatedwhen developing strategies for conserving biodiversity and environmental services.
Argentina: Camino del desendeudamiento (1991-2011)
Argentina: Camino del desendeudamiento (1991-2011)
Nemiña, Pablo Luis
El presente artículo analiza las transformaciones de la política financiera en la Argentina durante el período 1991-2011. Para ello, se estudian las principales acciones del Estado orientadas a enfrentar la problemática de la deuda pública y el financiamiento, así como las relaciones establecidas con el sector financiero y el FMI. La evolución de la política financiera argentina resalta uno de los contrapuntos más sobresalientes entre el período de la convertibilidad vigente hasta 2001 y la etapa posterior. El régimen de convertibilidad implicó el sostenimiento de una moneda nacional sobrevaluada, la cual determinó el progresivo incremento de la deuda pública y alentó el proceso de financiarización de la economía. En cambio, el régimen de la posconvertibilidad, apoyado en el mantenimiento de un tipo de cambio competitivo junto al superávit fiscal y comercial, ha contribuido a promover la actividad productiva por sobre la financiera. Esto, junto a la reestructuración de la deuda, ha permitido sostener un proceso de reducción gradual del endeudamiento público en términos relativos, liberando recursos para fomentar el mercado interno. Consecuentemente, con posterioridad a 2002 se observa una erosión de la capacidad de condicionamiento estructural sobre la dinámica del crecimiento de los acreedores, el FMI, y el sector financiero en general, en simultáneo con la obtención de mayores grados de autonomía financiera por parte del Gobierno Nacional. Finalmente, se analizan los desafíos que impone la crisis internacional a la continuación de este sendero.; This article analyzes the transformation in Argentina’s financial policies during the period of 1991-2011, examining the principal actions of the State oriented towards confronting the various problems of the public debt burden and its financing, as well as the relationships established with the financial sector and the IMF. The evolution of the country’s financial policies highlights one of the most notable differences between the period of convertibility, which ended in 2001, and the posterior period. The convertibility regime brought with it an overvalued currency, which determined the progressive increase in public debt and amplified the process of the financialization of the Argentine economy. On the other hand, the post-convertibility regime, supported by the maintenance of a competitive exchange rate together with fiscal and trade surpluses, has contributed to the promotion of productive over financial activity. Together with the debt restructuring, a process of gradual reduction in the relative weight of public debt has taken hold, freeing up resources to stimulate the domestic market. Consequently, after 2002 there is a clear erosion in the capacity of creditors, the IMF, and the financial sector in general to structurally condition growth dynamics; simultaneously, the national government gained greater degrees of financial autonomy. Finally, the article analyzes the challenges that the international crisis imposes on this evolution.
Los hidrocarburos no convencionales en el escenario energético argentino
Los hidrocarburos no convencionales en el escenario energético argentino
Pérez Roig, Diego
Desde diciembre de 2010, y sobre todo a partir del conflicto que Repsol mantuvo con el Estado nacional y los provinciales entre enero y mayo de 2012, se ha instalado en la agenda pública la necesidad de avanzar en la extracción de hidrocarburos no convencionales: depósitos de petróleo y gas alojados a gran profundidad en formaciones geológicas de baja porosidad y permeabilidad, cuyas reservas ubicarían a la Argentina en tercer lugar, detrás de China y Estados Unidos. En el siguiente trabajo analizaré los factores estructurales internos y externos que alientan esta potencial "revolución" del sector en el país, y sus posibles consecuencias sociales y ecológicas.
Convención Internacional de los Derechos del Niño: Hacia un abordaje desacralizador
Convención Internacional de los Derechos del Niño: Hacia un abordaje desacralizador
Barna Cingolani, Agustin Learco
Los estudios referentes a las formas de gestionar la niñez que no transita por los carriles esperados por las perspectivas hegemónicas han ganado, en las últimas décadas, cada vez más protagonismo. Desde principios de la década de los 90, en Argentina, muchos intelectuales comenzaron a visualizar en la Convención Internacional de los Derechos del Niño (CIDN) una posible vía emancipatoria para la niñez, en particular para los “menores” y a bregar por la adecuación de las normativas domésticas del país a los parámetros de la CIDN, como una herramienta que permita derrotar, cultural y materialmente, el denominado “paradigma de patronato”. Estos trabajos, si bien significan un aporte para la comprensión de las formas de gobierno de la infancia, portan asimismo un riesgo intrínseco, suelen concebir al enfoque de los derechos del niño como un bien en sí mismo, como un valor axiomático portador de un ideal moral superador. De este modo la CIDN se transforma en un ente abstracto y superior, ajeno a las prácticas sociales e históricas y, por ende, inaccesible al análisis crítico. Consideramos que perspectivas como estas corren el riesgo de esencializar sus objetos de indagación y velar la complejidad de los procesos sociopolíticos. Intentaremos, en este trabajo, realizar un ejercicio desacralizador, que resitué a la CIDN como un producto histórico particular, anclado en un contexto determinado y atravesado por relaciones de poder e intereses geopolíticos. A estos fines realizaremos un racconto histórico de las legislaciones transnacionales de niñez, así como ciertas tensiones y voces disonantes, hasta su punto culmine, la redacción de la Convención.; Studies concerning the ways of children managing, the ones that doesn’t fit well on the mainstream types expected by the elites, had gained an increasing interest in the last decades. In Argentina, since the beginnings of the nineties, many intellectuals began to visualize the Convention on the Rights of the Child (CRC) as a way to emancipate childhood, particularly those cataloged as “minors”. They also began to strive for the adequacy of domestic rules to the parameters of the CRC, as a tool that’d allow to defeat culturally and materially, the “patronage paradigm”. Although these analyses represented a contribution to understanding the ways of child government, they carry an inherent risk within: they usually tend to understand the children rights approach as a good in itself, as an axiomatic value that carries a transcending moral ideal. Thereby, the CRC becomes an abstract and superior entity, alien to the social and historical practices, and inaccessible to critical analysis. We believe that these perspectives carry the risk of essentializing their objects of inquiry and overshadowing the complexity of sociopolitical processes. In this paper we will try to carry out a desacralizing exercise that’d relocate the CRC as a particular historical product, anchored in a context, and crossed by power relations and geopolitical interests. For this porpoise, we will perform an historical inquest about the transnational legislation referring children, seeking out for dissonant voices and tensions, to its culminating point, the redaction of the CRC.
Visión absoluta y visión de lo absoluto en Nicolás de Cusa
Visión absoluta y visión de lo absoluto en Nicolás de Cusa; Absolute vision and vision of the Absolute in Nicholas of Cusa
D'amico, Claudia
Ao introduzir o tema da visão mística, Nicolau de Cusa mostra-se herdeiro da tradição neoplatônica enquanto supõe como fundamento de tal visão a própria visão absoluta. Contudo, seu pensamento privilegia o paralelismo entre a visão absoluta e a visão humana ao ponto de entender que, apenas na autocontemplação do dinamismo de sua visão, o homem pode fazer visível para si a visão de Deus.; Introducing the topic of the mystical vision, Nicholas of Cusa becomes the heir of the Neoplatonic tradition while he supposes as the foundation of such a view the same absolute vision. However, his thought is characterized by a parallelism between absolute and human vision to the point that the man can make himself visible the vision of God only by means of selfcontemplation of the dynamism of his own vision.
Endemicity analysis, parsimony and biotic elements: A formal comparison using hypothetical distributions
Endemicity analysis, parsimony and biotic elements: A formal comparison using hypothetical distributions
Casagranda, Maria Dolores; Taher, Leila Maria; Szumik, Claudia Adriana
There is as yet no general agreement regarding the most appropriate solution to the problem of identifying areas of endemism, not even in particular cases. In this study, we compared Endemicity Analysis (EA), Parsimony Analysis of Endemicity (PAE), and Biotic Elements Analysis (BE) based on their ability to identify hypothetical predefined patterns that represent nested, overlapping, and disjoint areas of endemism supported by species with different degrees of sympatry. We found that PAE performs poorly when applied to patterns that either overlap with each other or are supported by species with imperfect sympatry. BE exhibits a counterintuitive sensitivity to the degree of congruence among the distributions of endemic species, being unable to recognize areas of endemism supported by perfectly sympatric species. In contrast, in all cases examined we found that EA results in a high proportion of correctly identified distributional patterns. In addition to highlighting the strengths and limitations of these approaches, our results show how different methods can lead to seemingly conflicting conclusions and caution about the possibility of identifying distributional patterns that are merely methodological artefacts.
Improvements in the mechanical properties of the 18R↔6R high-hysteresis martensitic transformation by nanoprecipitates in CuZnAl alloys
Improvements in the mechanical properties of the 18R↔6R high-hysteresis martensitic transformation by nanoprecipitates in CuZnAl alloys
de Castro Bubani, Franco; Sade Lichtmann, Marcos Leonel; Lovey, Francisco Carlos
The 18R. ↔. 6R martensite-martensite transformation in Cu-based alloys exhibits large hysteresis, large pseudoelastic strain and weak transformation stress dependence on temperature. However, concomitant plastic deformation taking place in the 6R phase inhibits the use of these properties for applications. A novel approach to minimizing or even suppressing 6R plastic deformation during the 18R-6R transformation in CuZnAl shape-memory alloy single crystals with electronic concentration . e/. a=. 1.48 is presented. The method is based on a thermal treatment that introduces nanoprecipitates in the alloy. Results suggest that the role of CuZnAl shape-memory alloys in engineering should be reconsidered, as many energy damping applications could benefit from the huge hysteresis associated with the 18R-6R transformation, once the 6R plastic deformation is suppressed.
Historia epidemiológica de la tuberculosis en la Argentina. 1914-1947
Historia epidemiológica de la tuberculosis en la Argentina. 1914-1947
Carbonetti, Adrian
En el presente trabajo se analiza la mortalidad por tuberculosis en la República Argentina en el período comprendido entre 1914 y 1947. Esta etapa tiene fundamental importancia debido a que en ella se dio el mayor crecimiento de la mortalidad por esta enfermedad (1918) y luego un declive hasta llegar a valores mínimos en 1947. El comportamiento de la tuberculosis es coincidente con el proceso de transición epidemiológica que sufre la población argentina en este período de tiempo. Se analizan las tasas de mortalidad por tuberculosis a lo largo del período, se estudia la mortalidad por esta enfermedad según edad y sexo y se describe el recorrido de la mortalidad según las distintas regiones del territorio nacional.; In the present work the mortality analyzes for tuberculosis in the Republic Argentina in the period understood between 1914 and 1947. This stage has fundamental importance due to the fact that in her one gave the major growth of the mortality for this disease (1918) and then a decline up to coming to minimal values in 1947. The behavior of the tuberculosis is coincidental with the process of epidemiological transition that the Argentine population suffers in this period of time. The rates of mortality are analyzed by tuberculosis throughout the period, the mortality is studied by this disease according to age and sex and the tour of the mortality is described according to the different regions of the national territory.
Eugenia Sacerdote de Lustig: mujeres pioneras de la investigación oncológica
Eugenia Sacerdote de Lustig: mujeres pioneras de la investigación oncológica
Pérgola, Federico
En los últimos días de noviembre de 2011, exactamente durante el domingo 27, falleció en Buenos Aires la Dra. Eugenia Sacerdote de Lustig. Murió a los 101 años y la sobrevive su prima hermana, algunos meses mayor, la Dra. Rita Levi Montalcini, premio Nobel de Medicina. Soportó discriminaciones, una de ellas por la mente febril de un dictador de turno de su Italia natal, don Benito Mussolini que fue de tipo racial. La otra que suponemos que la hubo, la de género: era mujer y se “atrevía” a investigar en la década del 40 cuando todo era patrimonio masculino.
De la construcción del conocimiento científico a su enseñanza : distintas explicaciones sobre la estructura del benceno
De la construcción del conocimiento científico a su enseñanza : distintas explicaciones sobre la estructura del benceno; From scientific knowledge construction to teaching. Several explanations about benzene structure
Farré, Andrea Soledad; Lorenzo, Maria Gabriela
La revisión de la evolución histórica para representar cierto compuesto, en este caso benceno, pone de manifiesto las diferentes teorías que pugnaron por dar las mejores explicaciones, mostrando una visión dinámica acerca de la construcción del conocimiento científico. Los principales factores que han influido sobre el conocimiento acerca de la estructura del benceno son la composición elemental y el establecimiento de la fórmula empírica, el reconocimiento de isómeros, la reactividad química, la disponibilidad de nuevos dispositivos tecnológicos y las teorías de enlace químico (teoría estructural, teorías atómicas, teoría de enlace de valencia y la teoría de orbitales moleculares). Este trabajo podrá ser de utilidad para la capacitación de profesores y tal vez eche luz sobre algunas dificultades de aprendizaje de los estudiantes. También, resulta un modelo útil para que los profesores puedan desarrollar futuras investigaciones junto con sus estudiantes, incluyendo activamente al conocimiento meta-científico en sus prácticas de aula.; From scientific knowledge construction to teaching. Several explanations about benzene structure. Reviewing the historical development to represent a compound, in this case benzene, displays the different theories that struggled to give the best explanations, showing a dynamic vision for the scientific knowledge construction. The elemental composition and the establishment of the empirical formula, the recognition of isomers, the chemical reactivity, the availability of new technological devices and chemical bond theories (the structural theory, atomic theories, valence bond theory and molecular orbital theory) are the main factors that influenced knowledge about the structure of benzene. This work can be useful in teachers’ training and perhaps enlightens on some students learning difficulties. This also is a useful model for future research that teachers can develop with their students including the meta-scientific knowledge actively in the classroom.
The Development of More Accurate QSAR Techniques
The Development of More Accurate QSAR Techniques
Lee, Adam; Mercader, Andrew Gustavo; Castro, Eduardo Alberto; Duchowicz, Pablo Román
QSAR is a very effective starting step in the development of compounds for vast numbers of industries. Its scale and importance, especially in the medicinal field means it is a dynamic area to research. The size of QSAR also presents problems; there are many different methods in use for each of the steps in a study, from the descriptors in use, to the type of linear regression to apply to the descriptors. The idea was to put forward models that improved upon the existing methods to such a degree that it could become a universal method for QSAR modelling. This project successfully investigated in detail an improvement to the existing methods to choose the correct number of descriptors to include in the model by using Rloo analysis; this resulted in a simpler model compared to previous methods. K – Means clustering was also investigated as part of a novel, variable independent method. This methodology only uses one descriptor as opposed to general QSAR studies which use several. The results for 12 out of the 14 sets were at least as accurate as the results obtained by existing linear methods. An example using PERM; the Stest obtained using the novel method was 0.46 compared to the Stest of 0.53 obtained by using current linear methods. The simplicity associated with the K - Means clustering method and the fact it shows improved predictive potential could lead to an overhaul of all current, more complicated methods in favour of the simpler K- Means based method.
Mating success depends on rearing substrate in cactophilic Drosophila
Mating success depends on rearing substrate in cactophilic Drosophila
Hurtado, Juan Pablo; Soto, Eduardo Maria; Orellana, Liliana; Hasson, Esteban Ruben
Drosophila buzzatii and D. koepferae coexist in the arid lands of southern South America and exploit different types of cactus as breeding hosts. The former prefers to lay eggs on the rotting pads of prickly pears (genus Opuntia) whereas D. koepferae exhibits greater acceptance for columnar cacti (e. g., Echinopsis terschekii). Here, we demonstrate that the rearing cacti affect male mating success, flies reared in each species' preferred host exhibited enhanced mating success than those raised in secondary hosts. Opuntia sulphurea medium endows D. buzzatii males with greater mating ability while D. koepferae males perform better when flies develop in Echinopsis terschekii. These effects are not mediated through body size, even in D. buzzatii whose body size happens to be affected by the rearing cacti. This scenario, which is consistent with the evolution of host specialization and speciation through sensory drive, emphasizes the importance of habitat isolation in the coexistence of these cactophilic Drosophila.
Neuroprotective effects of human umbilical cord mesenchymal stromal cells in an immunocompetent animal model of Parkinson's disease
Neuroprotective effects of human umbilical cord mesenchymal stromal cells in an immunocompetent animal model of Parkinson's disease
Mathieu, Patricia Andrea; Roca, Valeria Ines; Gamba, Cecilia; del Pozo, Ana; Pitossi, Fernando Juan
Microglial activation in the substantia nigra (SN) is a ubiquitous feature in PD which could mediate toxic effects. Human mesenchymal stromal cells (hMSCs) possess immunomodulatory properties. We evaluated whether the transplantation of hMSCs obtained from umbilical cord had a neuroprotective effect in a not-immunosuppressed rat Parkinson's disease (PD) model. Rats receiving hMSCs in the SN displayed significant preservation in the number of dopaminergic neurons in the SN at 21. days after lesion and an improved performance in behavioral tests compared to control rats. However, no differences in any inflammatory parameter tested were found. These results suggest that grafted hMSCs exert neuroprotection but not neuromodulatory effects on degenerating dopaminergic neurons.
Experimental infection of rabbits (Oryctolagus cuniculus) with Brucella suis biovar 1 isolated from wild hares (Lepus europaeus)
Experimental infection of rabbits (Oryctolagus cuniculus) with Brucella suis biovar 1 isolated from wild hares (Lepus europaeus)
Fort, Marcelo; Baldone, Valeria; Fuchs, Lumila Ivana; Giménez, Hugo; Rojas, María; Breccia, Javier Dario; Oyhenart, Jorge
Brucella suis biovar 1 is the causative agent of brucellosis in several domestic and wild animals and it is a common agent of human brucellosis. European hares (Lepus europaeus) have been shown to be infected by B. suis biovar 1 and the transmission to other animals has been suggested. In this work, experimental rabbits (Cuniculus orictolagus) were infected with B. suis biovar 1 isolated from wild hares. Infected rabbits showed high serological response in 2 weeks after discharge and typical granulomatous lesions (2. mm diameter) were found in liver, spleen and kidneys after 50 days. B. suis biovar 1 was cultured from the lesion of the organs mentioned above as well as from urine, placenta and fetuses. These data suggest that hares are a potential source for horizontal transmission of B. suis biovar 1 to other mammalians.
Efficient energy transfer via the cyanide bridge in dinuclear complexes containing Ru(ii) polypyridine moieties
Efficient energy transfer via the cyanide bridge in dinuclear complexes containing Ru(ii) polypyridine moieties
Cadranel, Alejandro; Alborés, Pablo; Yamazaki, Shiori; Kleiman, Valeria D.; Baraldo Victorica, Luis Mario
We report the synthesis, structure and properties of the cyanide-bridged dinuclear complex ions [Ru(L)-(bpy)(μ-NC)M(CN)5]2−/− (L = tpy, 2,2′;6′,2′′-terpyridine, or tpm, tris(1-pyrazolyl)methane, bpy = 2,2′- bipyridine, M = Fe(II), Fe(III), Cr(III)) and the related monomers [Ru(L)(bpy)X]2+ (X = CN− and NCS−).All the monomeric compounds are weak MLCT emitters (λ = 650?715 nm, ϕ ≈ 10−4). In the Fe(II) and Cr(III) dinuclear systems, the cyanide bridge promotes efficient energy transfer between the Ru-centered MLCT state and a Fe(II)- or Cr(III)-centered d?d state, which results either in a complete quenching of luminescence or in a narrow red emission (λ ≈ 820 nm, ϕ ≈ 10−3) respectively. In the case of Fe(III) dinuclear systems, an electron transfer quenching process is also likely to occur.
Global W 2,p estimates for nondivergence elliptic operators with potentials satisfying a reverse Hölder condition
Global W 2,p estimates for nondivergence elliptic operators with potentials satisfying a reverse Hölder condition
Bramanti, M.; Brandolini, L.; Harboure, Eleonor Ofelia; Viviani, Beatriz Eleonora
In this article, we give some a priori L p(ℝ n) estimates for elliptic operators in nondivergence form with VMO coefficients and a potential V satisfying an appropriate reverse Hölder condition, generalizing previous results due to Chiarenza-Frasca-Longo to the scope of Schrödinger-type operators. In particular, our class of potentials includes unbounded functions such as nonnegative polynomials. We apply such a priori estimates to derive some global existence and uniqueness results under some additional assumptions on V.
Difficulties of undergraduate students in the organic chemistry laboratory
Difficulties of undergraduate students in the organic chemistry laboratory
Lorenzo, Maria Gabriela; Reverdito, Ana Maria; Blanco, Mercedes; Salerno, Alejandra
In order to study the learning difficulties of university students in the organic chemistry laboratory, a new Model for the Analysis of Experimental Work (MAEW) was developed. This article is organized into three parts: first, a historical look at the role of experimental work in science education, including the purpose of the laboratory class; next, a description of the MAEW; finally, we show how the MAEW can be applied to an actual laboratory class of organic chemistry. An original proposal for the classification of the materials used in an organic chemistry laboratory is also offered.
Nucleophile- or light-induced synthesis of 3-substituted phthalides from 2-formylarylketones
Nucleophile- or light-induced synthesis of 3-substituted phthalides from 2-formylarylketones
Gerbino, Darío César; Augner, Daniel; Slavov, Nikolay; Schmalz, Hans Günther
The surprisingly facile conversion (isomerization) of 2-formyl-arylketones into 3-substituted phthalides, as observed for the marine natural product pestalone and its per-O-methylated derivative, was investigated using a series of simple 2-acylbenzaldehydes as substrates. The transformation generally proceeds smoothly in DMSO, either in a Cannizarro-Tishchenko-type reaction under nucleophile catalysis (NaCN) or under photochemical conditions (DMSO, 350 nm). © 2012 American Chemical Society.
Assessment of water quality in temperate-plain streams (Argentina, South America) using a multiple approach
Assessment of water quality in temperate-plain streams (Argentina, South America) using a multiple approach; Evaluación de la calidad del agua mediante un enfoque múltiple en arroyos de la llanura templada (Argentina, América del Sur)
Ocon, Carolina Silvia; Rodrigues Capitulo, Alberto
We assessed the water quality in two pampean lotic systems (Argentina), the Juan Blanco and Buñirigo streams, subjected to different land uses (i. e., the UNESCO Biosphere Nature Reserve versus industry and agriculture, respectively) through measurements of physicochemical data and the structural parameters of the macroinvertebrate assemblages in addition to ecotoxicological analyses. The objective was to identify the degree of ecological impairment in adversely affected areas and the consequent effects on the biota. The results obtained allowed the establishment of different water-quality classes within the study area. According to the indices applied, the downstream zone of the Buñirigo stream was categorized as moderately polluted on the basis of losses of sensitive benthic species or changes in their abundance. Likewise, acute ecotoxicological bioassays demonstrated that the water from this site had lethal effects on Caenis nemoralis (Ephemeroptera: Caenidae) larvae. This sampling point also exhibited relevant physicochemical features, such as high water conductivity and nutrient levels as well as low contents of dissolved oxygen.; Se realizó un estudio de la calidad del agua en dos sistemas lóticos, los arroyos Juan Blanco y Buñirigo (Argentina), sujetos a diferente uso del suelo (el primero se ubica dentro de una reserva de Biosfera de la UNESCO, mientras que el segundo en una zona agrícolo-ganadera e industrial). Se analizaron datos físico-químicos, parámetros estructurales del ensamble de macroinvertebrados y ensayos ecotoxicológicos. El objetivo fue identifi car el grado de deterioro en las áreas afectadas por efl uentes y los consiguientes efectos sobre la biota. Los resultados obtenidos permitieron establecer diferentes clases de calidad del agua dentro de la zona de estudio. De acuerdo a los índices aplicados la cuenca baja del arroyo Buñirigo fue caracterizada como moderadamente contaminada sobre la base de la pérdida de especies bentónicas sensibles o cambios en su abundancia. Del mismo modo, los ensayos ecotoxicológicos agudos demostraron que el agua de este sitio tuvo efectos letales sobre larvas de Caenis nemoralis (Ephemeroptera: Caenidae). Este punto de muestreo también evidenció características físico-químicas desfavorables para la biota, como alta conductividad y niveles de nutrientes, así como bajo contenido de oxígeno.
Ethanol-induced locomotor activity in adolescent rats and the relationship with ethanol-induced conditioned place preference and conditioned taste aversion
Ethanol-induced locomotor activity in adolescent rats and the relationship with ethanol-induced conditioned place preference and conditioned taste aversion
Acevedo, María Belén; Nizhnikov, Michael; Spear, Norman E.; Molina, Juan Carlos; Pautassi, Ricardo Marcos
Adolescent rats exhibit ethanol-induced locomotor activity (LMA), which is considered an index of ethanol's motivational properties likely to predict ethanol self-administration, but few studies have reported or correlated ethanol-induced LMA with conditioned place preference (CPP) by ethanol at this age. The present study assessed age-related differences in ethanol's motor stimulating effects and analyzed the association between ethanol-induced LMA and conventional measures of ethanol-induced reinforcement. Experiment 1 compared ethanol-induced LMA in adolescent and adult rats. Subsequent experiments analyzed ethanol-induced CPP and conditioned taste aversion (CTA) in adolescent rats evaluated for ethanol-induced LMA. Adolescent rats exhibit a robust LMA after high-dose ethanol. Ethanol-induced LMA was fairly similar across adolescents and adults. As expected, adolescents were sensitive to ethanol's aversive reinforcement, but they also exhibited CPP. These measures of ethanol reinforcement, however, were not related to ethanol-induced LMA. Spontaneous LMA in an open field was, however, negatively associated with ethanol-induced CTA.
Páginas
