Nuclear receptors: a historical perspective Mazaira, Gisela Ileana; Zgajnar, Nadia Romina; Lotufo, Cecilia Maricel; Daneri Becerra, Cristina del Rosario; Sivils, Jeffrey C.; Soto, Olga B.; Cox, Marc B.; Galigniana, Mario Daniel These receptors exhibit a multitude of roles in cell biology and hence have attracted a great deal of interest in the drug discovery field. It is not certain whether these receptors evolved independently or an ancestral protein acquired various functions upon binding to preexisting small molecules, ligands. Currently, members of this receptor superfamily are categorized in six groups, including ?orphan receptors.? Research in the area has resulted in several clinically used drugs and continues to reveal further previously unknown roles for these receptors paving the road toward more valuable discoveries in the future.

The geopolitics of moral panic: The influence of Argentinian neo-conservatism in the genesis of the discourse of 'gender ideology' Moran Faundes, Jose Manuel Ferrucio ´Gender Ideology´ discourse has been one of the most recurrent strategies of neo-conservative activism at a global level. Through this syntagma, a variety of moral panics are mobilized against feminist agendas and LGBTI rights, accusing them of promoting the destruction of natural order, the spread of Marxism and global conspiracy. Academic literature has highlighted that the genesis of this strategic discourse was an intellectual production in the mid-1990s; we can trace back texts written in conjunction by secular neo-conservative intellectuals in the United States and members of the Catholic hierarchy. However, the tendency was to ignore the strong intellectual production that neo-conservative activists developed at that time in Argentina, particularly in Córdoba and Buenos Aires, which helped to lay the foundations of the present ´gender ideology´ discourse. The intention of this work is to draw attention to that local production and its connection with the ideas that were being developed in parallel in the global North. In order to do this, we will analyze a series of texts produced by neo-conservatives in Argentina in the 1990s.

ELSA cohort 2014: Association of age of first drink and progression from first drink to drunkenness on alcohol outcomes in Argentinean college freshmen Vera, Belén del Valle; Pilatti, Angelina; Pautassi, Ricardo Marcos College freshman are at-risk for hazardous alcohol drinking and for experiencing alcohol-related negative consequences. This is exacerbated in those featuring an early age of first alcohol use or of first drunkenness. It remains unclear which of these milestones is more strongly associated with alcohol outcomes. We examined, in Argentinean college drinkers (n = 4088; 43% men; racially and ethnically homogeneous), the association of age at drinking onset and progression to drunkenness (drunkenness naïve [Drunk-Naïve]; No-Delay [same age of first alcohol use and first alcohol intoxication]; one year of delay between age of first alcohol use and first alcohol intoxication; ≥2years of delay) on several alcohol outcomes. Methods: A survey measured substance use, age at drinking and drunkenness onset and alcohol-related consequences. Results: Alcohol consumption per drinking occasion was significantly greater in men than in women. An early drinking onset (alcohol use before age 13) and lifetime drunkenness independently exacerbated alcohol consumption per drinking occasion and during the last year. In men, Early-Onset was associated with a greater number of alcohol-related consequences when the delay between Early-Onset and the first drunkenness episode was 1 or ≥2 years yet did not significantly alter the number of negative consequences in Drunk-naïve or No-delay drinkers. In women, Early-Onset significantly enhanced the number of negative consequences when the delay was two years, but not when the delay was one-year or in Drunk-naïve or No-delay drinkers. Conclusions: The window between the first contact with alcohol and the first episode of drunkenness is a critical period to reduce alcohol-related problems.

Whey protein-kefiran films as driver of probiotics to the gut Gagliarini, Nina María; Diosma, Gabriela; Garrote, Graciela Liliana; Abraham, Analia Graciela; Piermaria, Judith Araceli In this work, an alternative matrix for probiotics delivery constituted by whey proteins and polysaccharide kefiran was investigated. Edible transparent and homogeneous films containing the microorganisms Lactobacillus paracasei CIDCA 8339 and Kluyveromyces marxianus CIDCA 8154 with probiotic characteristics have been developed. Inclusion of microorganisms did not modify thickness, color or mechanical characteristics of films. This matrix showed good capability protecting the included probiotics from stress during film obtaining process and through gastrointestinal passage simulation. At the end of the applied gastrointestinal tract model, 7.1.105 CFU/ cm2 K. marxianus CIDCA 8154 and 1.65.107 CFU/cm2 L. paracasei CIDCA 8339 remain viable, having decreased less than 0.6 logarithm cycle with respect to those originally included, even after 57 days of films storage.

Fabrication and Characterization of Hollow Microcapsules from Polyelectrolytes Bearing Thymine Pendant Groups for Ultraviolet-B (UVB)-Induced Crosslinking Gimenez, Rodrigo Esteban; Serrano, Mariana Paula; Alvarez, Rosa Maria Susana; Martino, Debora Marcela; Borsarelli, Claudio Darío DNA - bioinspired polyelectrolytes poly[vinylbenzylthymine (VBT)-4-vinylbenzyltriethylammonium chloride (VBA)] and poly[vinylbenzylthymine (VBT)-4-vinylphenylsufonate (VPS)] were used for the preparation of hollow microcapsules (HMC) using the layer-by-layer method and CaCO3 microspheres as removable molds. Stable aqueous suspensions of spherical-shaped HMCs with a shell composed of six layers of VBA-based polyelectrolytes were obtained, of approximately (7.0±1.5) μm diameter and a shell thickness of 1 μm. Ultraviolet-B irradiation of the HMC suspensions induces an efficient crosslinking between adjacent polyelectrolyte chains through the formation of thymine photodimers, such as the cyclobutane pyrimidine dimer (CPD) and the (6?4) pyrimidine?pyrimidone photoproduct (6?4PP). This process resulted in a reduction of the average interstitial mesh size of the HMC shells, modulating their permeability properties and increasing the mechanical stability of the HMC without a noticeable modification of size and shape. Thus, the DNA-bioinspired polyelectrolytes are promising materials for the preparation of UVB-responsive HMCs.

Brittle stars from the Lower Cretaceous of Patagonia: first ophiuroid articulated remains for the Mesozoic of South America; Ofiuroideos del Cretácico Inferior de Patagonia: primer registro fósil articulado para el Mesozoico de América del Sur Fernández, Diana Elizabeth; Giachetti, Luciana María; Stöhr, Sabine; Thuy, Ben; Perez, Damián; Comerio, Marcos; Pazos, Pablo Jose The first articulated remains of ophiuroids for the Mesozoic of South America are described from the Lower Cretaceous of Neuquén Basin, Argentina. The taxonomic analysis allows the assignment of the material described herein to the extinct genus Ophiopetra. The specimens belong to a new species, but considering the poor preservation, a new name is not introduced, as it would be based on an incomplete diagnosis. Certain characteristics (e.g., the diameter of the disc, the width/height ratio of the vertebrae) suggest that these ophiuroids are paedomorphic specimens. In light of the latest classification of the Ophiuroidea, and new insights on the spine articulation microstructure of Ophiopetra lithographica presented herein, a transfer of Ophiopetra to the family Ophionereididae within the order Amphilepidida is proposed. This material expands the palaeogeographic record of this genus, since it represents the first remains of Ophiopetra described in the Southern Hemisphere. It is also the first Cretaceous record of the genus worldwide.

Germination response to osmotic potential, osmotic agents, and temperature of five halophytes occurring along a salinity gradient Piovan, María Julia; Pratolongo, Paula Daniela; Donath, Tobias W.; Loydi, Alejandro; Eckstein, Rolf Lutz Premise of research. Halophyte species grow where salt concentrations are high. Still, their germination may be affected by salts, either by creating an osmotic potential that prevents water uptake or by dissociating in ions that can cause different grades of toxicity. With the increase of salinized areas, it becomes important to understand the behavior of these species. Methodology. We studied how the germination of five halophyte species that occur along a salinity gradient in the Bahía Blanca coastal zone, Atriplex undulata, Cyclolepis genistoides, Allenrolfea patagonica, Sarcocornia perennis, and Heterostachys ritteriana, responds to variations in osmotic agents, osmotic potential, and temperature. Seeds were exposed to different osmotic potentials using NaCl (neutral salt), Na2CO3 (alkaline salt), and mannitol solutions in a germination chamber experiment. Germination was recorded during 42 d. Germination percentage, mean germination time, and synchrony were calculated. Pivotal results. Our experimental results showed that for the five halophyte species under study, germination was mostly driven by osmotic potentials and osmotic agents. At high osmotic potential, the germination response did not differ significantly from controls, except for Allenrolfea and Cyclolepis, which showed lower germination when treated with Na2CO3. Low osmotic potentials and Na2CO3 were detrimental to germination, reflected by lower germination percentages, higher mean germination times, and lower synchrony. Conclusions. In general, the response to the alkaline salt was more negative than that to the neutral salt or mannitol, regardless of the species. Each species showed a different response to the salts under study, and this response matched well with the distribution of species along the salinity gradient observed in the field.

Biomimetic Cu, Zn and Cu2 complexes inserted in mesoporous silica as catalysts for superoxide dismutation Patriarca, Matías Ezequiel; Daier, Veronica Andrea; Camí, Gerardo Enrique; Pellegri, Nora Susana; Rivière, Eric; Hureau, Christelle; Signorella, Sandra Rosanna Three CuZn-superoxide dismutase (SOD) functional mimics, [CuZn(dien)2(μ-Im)](ClO4)3 (1), [Cu2(dien)2(μ-Im)](ClO4)3 (2) (Im = imidazole, dien = diethylenetriamine), and [CuZn(salpn)Cl2] (3) (H2salpn = 1,3-bis(salicylideneamino)propane), were successfully inserted into the nanochannels of SBA-15 type mesoporous silica with retention of the silica mesostructure. X-ray absorption spectroscopic studies indicate that the encapsulated complexes keep unchanged the first-shell environment of Cu(II) and Zn(II) ions. Magnetic measurements suggest that the nanochannels constrain the geometry of the μ-imidazolate-Cu(II)2 core modifying the relative orientation of the two copper coordination planes. Confinement imposed by the silica nanochannels upon encapsulation of complexes 1 and 2 leads to stable hybrid materials at physiological pH with enhanced SOD activity relative to the free complexes. Unlike the imidazolato-bridged compounds, insertion of 3 in mesoporous silica leads to a less stable hybrid material exhibiting partial release into the aqueous solution and O2•− dismutation rate slower than the free complex. The covalent binding of a mononuclear Cu(dien)Im+ moiety to the mesoporous silica showed lower SOD activity than encapsulated imidazolato-bridged CuZn and Cu2 complexes. The results emphasize the positive effect of encapsulation on SOD activity of imidazolato-bridged dinuclear complexes.

Fortalezas, debilidades y oportunidades de la política de gestión diferenciada de residuos para grandes generadores del área metropolitana de Buenos Aires (2013-2017). ¿Promoción del reciclaje inclusivo o más de lo mismo?; Strengths, weaknesses and opportunities of the waste management policy oriented to the big generators of the metropolitan area of Buenos Aires (2013-2017). Promotion of inclusive recycling or more of the same? Sarandón, Faustina; Schamber, Pablo Javier La política de gestión diferenciada de residuos para grandes generadores impulsada por la autoridad ambiental de la Provincia de Buenos Aires en el año 2013, auguraba un cambio sustancial en el tratamiento de los residuos sólidos urbanos. Con su entrada en vigencia, los grandes generadores debían gestionar sus propios residuos separándolos en al menos dos fracciones (reciclables y no reciclables) y asumir el costo de su transporte y tratamiento. Dichas normativas buscaban además promover la inclusión social de los recuperadores urbanos habilitando su participación mediante la organización de cooperativas. Desde un enfoque de las políticas públicas como proceso, este trabajo expone análisis iniciales sobre los efectos que dicha política ha venido teniendo sobre actores que la protagonizan.; The policy of differentiated management of waste for large generators promoted by the environmental authority of Buenos Aires Province in 2013, predicted a substantial change in the treatment of urban solid waste. Through them, big generators had to manage their own waste by separating them into at least two fractions (recyclable and non-recyclable) and to assume the cost of transporting and treating them. These regulations also sought to promote the social inclusion of waste pickers enabling their participation through the organization of cooperatives. From an approach of the public policies as process, this work exposes initial analyzes on the effects that this policy has been having on actors that carry it out.

Los avatares de la mancomunión. Propiedad indivisa, armonías y conflictos en las costas del río Dulce. Santiago del Estero, siglos XVIII y XIX; The vicissitudes of Mancomunión. Undivided property, harmony and conflict in the Rio Dulce region. Santiago del Estero (Argentina), eighteenth and nineteenth centuries Farberman, Judith En Santiago del Estero, noroeste de Argentina, se denominaba «mancomún» a las propiedades indivisas gestionadas colectivamente. Este tipo de estructura agraria tuvo relativa difusión durante la colonia y el siglo XIX y puede relevarse tanto en grandes estancias como en propiedades campesinas. En este artículo se profundizan tres cuestiones a partir de ejemplos coloniales de la zona del río Dulce: la racionalidad, la membresía y las jerarquías de los campos comunes.

Effect of cesium incorporation in hydrotalcite-like compounds Balsamo, Nancy Florentina; Mendieta, Silvia Nazaret; Vasiliev, Aleksey; Crivello, Mónica Elsie Hydrotalcite-like compounds are synthetic anionic clays that have outstanding adsorption and catalytic properties. Hydrotalcite nanoclays (Mg–Al layered hydroxides) were synthesized by co-precipitation method. Obtained solids were converted into mixed metal oxides by thermal decomposition at temperatures up to 723 K. High adsorption and reconstructive properties of the mixed metal oxides allowed incorporating metal ions in their structure. Thus, these materials can be used as ion traps from aqueous media. Cesium ions were incorporated into hydrotalcite lamellar structure by impregnation method. Effects of different loads of Cs+ and adsorption times on the material properties were studied. The materials were characterized by X-ray diffraction, surface area analysis, scanning electron microscopy, energy dispersive X-ray spectrometry for obtaining a localized chemical analysis, and temperature-programmed desorption of CO2 for measurement of basic sites density. The amounts of metal incorporated in the structure was high enough due to small size of Cs+ ion. Synthetized materials also demonstrated high concentrations of strong surface basic sites formed through a synergistic effect of Cs and Mg ions. Basic properties of Cs-containing hydrotalcites enable their potential use as catalysts of base-catalyzed reactions.

Estrategias biológicas destinadas a combatir Escherichia coli enterohemorrágica en carne y productos cárnicos: Estudios bioquímicos y tecnológicos Orihuel, Alejandra Escherichia coli enterohemorrágica (ECEH) constituye una gran preocupación para la sostenibilidad de la industria de la carne y una grave amenaza para la salud pública a nivel mundial. La infección humana por ECEH ocurre a través de la ingestión de alimentos contaminados, principalmente carnes picadas. Además, el 5-10% de los pacientes infectados con ECEH (especialmente niños y adolescentes) desarrollan una grave patología, el Síndrome Urémico Hemolítico. Argentina es, a nivel mundial, el país con mayor incidencia de esta enfermedad. En este contexto urge la necesidad de proporcionar a la industria de la carne soluciones sustentables para limitar y prevenir riesgos. Las bacterias lácticas (BL), presentes de forma natural en la carne, son de gran interés tecnológico debido a la capacidad de ciertas cepas para inhibir microorganismos patógenos y/o deteriorantes en alimentos. Además, las BL generalmente se consideran seguras (GRAS), de manera que su uso como bioprotectores en alimentos constituye una estrategia real. Sin embargo, hasta el momento no se dispone en el mercado de un cultivo láctico capaz de inhibir ECEH en carne. En este contexto, el objetivo de este trabajo fue determinar el potencial de cepas BL para inhibir a ECEH en carne y estudiar las bases moleculares subyacentes a la interacción entre BL-ECEH. Las cepas de BL estudiadas (Lactobacillus curvatus CRL705, Lactobacillus plantarum CRL681 y Enterococcus mundtii CRL35) fueron preseleccionadas por sus óptimas características bioquímicas y tecnológicas. Como patógeno modelo se utilizó la cepa atoxigénica E. coli O157:H7 NCTC12900. Cada cepa de BL fue cocultivada con ECEH en un medio experimental cárnico. Ent. mundtii CRL35 resultó seleccionada como candidato por su significativa capacidad anti ECEH. Este efecto demostró ser independiente de la acción de bacteriocina, del ácido u otro agente soluble producido por Ent. mundtii, sugiriendo la interacción célula-célula como uno de los mecanismos implicados en la inhibición. Mediante un enfoque proteómico comparativo se estudió las bases moleculares subyacentes a esta interacción bacteriana, pudiéndose correlacionar con éxito el perfil de proteínas sobreexpresadas con la fisiología de Ent. mundtii y una ventaja competitiva de la BL sobre el patógeno. Al estudiar el fenómeno de adhesión/colonización del alimento por ambos microorganismos, se observó una ventaja competitiva de Ent. mundtii con respecto a E. coli, en la unión a proteínas claves de la matriz extracelular cárnica. Finalmente, se diseñó un sistema experimental constituido por carne molida con el objetivo de evaluar la acción bioprotectora de Ent. mundtii in situ. Se observó un efecto bacteriostático de la BL sobre ECEH, aunque de menor magnitud que aquél observado in vitro. Este resultado sugiere la necesidad de ensayos tecnológicos adicionales para optimizar la acción bioprotectora de esta cepa en un escenario real. Este trabajo de tesis Doctoral, es pionero en los estudios de interacción entre una BL y un patógeno como ECEH, aplicando un enfoque multidisciplinario. Los resultados obtenidos contribuyen directamente a la tecnología de alimentos cárnicos, proponiéndose por primera vez un cultivo láctico contra ECEH, un patógeno alimentario que demanda soluciones urgentes en nuestro país.

Multi-source multiple change on belief bases Tamargo, Luciano Héctor; Deagustini, Cristhian Ariel David; García, Alejandro Jorge; Falappa, Marcelo Alejandro; Simari, Guillermo Ricardo In a multi-agent system, an agents belief base can be modified when that agent receives information from other agents. Here, we study the case when these belief base changes occur in a collaborative multi-agent system environment, and the agents in the system exhibit different degrees of credibility; the former assumption guarantees that the agents are truthful and they help each other, and the latter introduces the opportunity of choosing the best possible source of information Belief Revision in Multi-Agent Systems has been analyzed in where the distinction between Multi-Agent Belief Revision (MABR) and Individual Belief Revision (IBR) is explained on the one hand, MABR studies the overall belief revision be-havior of agent teams in which, to pursue the mutual goal, the involved agents need to communicate, cooperate, coordinate, and negotiate with one another. On the other hand, IBR is divided into two different areas: belief revision in a single agent environment called Single agent Belief Revision (SBR) and individual belief revision in a multi-agent environment called Multi-Source Belief Revision (MSBR). In this last area, an individual belief revision process is carried out in a multi-agent environment where the new information may come from multiple sources that may be in conflict. We can also distinguish two types of MSBR: unitary MSBR where an agent can receive from different informant agents an atomic piece of information (see for instance, and conjunctive MSBR where the received information is a set of objects, probably provided by one or more sources. Our proposal is focused on the latter approach.

Open circuit potentiometry reports on internal redox states of cells in G. Sulfurreducens biofilms Schrott, Germán David; Bonanni, Pablo Sebastian; Busalmen, Juan Pablo The outstanding capacity of Geobacter sulfurreducens cells to directly connect their inner electron transport chain to a polarized electrode have prompted the application of a wide arrange of electrochemical techniques to explore their metabolism and current production possibilities. In this work we use very basic electrochemical assays as open circuit potential, voltammetric and chronopotentiometric measurements to obtain fundamental information on bacterial electrochemical characteristics of importance to interpret bacterial functioning. Specifically, we obtained information on G. sulfurreducens biofilm capacity to store charge in three major molecular reservoirs bridging the gap between NADH and the electrode, demonstrating, at the same time, the value of OCP measurements as a reporter of internal redox state of cells.

La semiosis “social” de las biomoléculas; The “Social” Semiosis of Biomolecules Rodriguez, Pablo Esteban El artículo estudia el modo en que la genética actual emplea nociones provenientes de las ciencias y de las prácticas relativas al lenguaje oral o escrito para comprender la actividad de las biomoléculas: código, expresión, silenciación, edición son algunos de estos términos. Propone un itinerario que comienza con formulaciones generales que, desde el siglo XIX, aludían a un código biomolecular para culminar en la amalgama entre biología molecular y teoría tecnológica de la información desarrollada por el Dogma Central de la biología molecular en los años 1950. Luego, a partir del concepto de código genético, se analizan los modelos de comprensión aplicados por las propias ciencias del lenguaje a la genética: la lingüística molecular, la biosemiótica y la relación de ambas con los clásicos modelos comunicacionales de emisor-mensaje-receptor, al que alude directamente el Dogma Central, mostrando los límites de los diferentes modelos y su vínculo con algunos hallazgos experimentales recientes de la biología molecular. Finalmente, se sugiere que la teoría de los discursos sociales de E. Verón podría ser tomada como un nuevo modelo “bio-significante”. Se pretende con ello realizar un aporte al campo de las ciencias de la comunicación mediante la inclusión de ciertos aspectos de la biología molecular dentro de su égida.; The article studies the way in which the current genetics uses notions from the sciences and practices related to oral or written language to understand the activity of biomolecules: code, expression, silencing, edition they are some of these terms. It proposes an itinerary beginning with the general formulations that, from the 19th century, referred to a biomolecular code and ending with the fusion between molecular biology and technological theory of the information developed by the Central Dogma of the molecular biology in the 1950 decade. Then, based on the notion of genetic code, models of comprehension applied by the sciences of the language to the genetics were analyzed: molecular linguistics, biosemiotics and the relationship of both with the classic communication models of sender–message-receiver, mentioned directly by the Central Dogma, showing the limits of the different models and the link with some recent experimental discoveries of molecular biology. Finally, it is suggested that the theory of the social discourses of E. Verón might be taken as a new "bio-significant" model. With this approach, it is expected to contribute to the field of the communication sciences by including certain aspects of the molecular biology under its aegis.

Phytoremediation, a biotechnology with important applications Pérez Cuadra, Vanesa; Espósito, Martín Eduardo The pollutants found in the environment, of natural origin and as a result of human activity,generate a negative impact on ecosystems. The resolution of this type of problems through the application of environmentally friendly technologies are of extreme necessity, one of these technologies is phytoremediation. Pollution with different types of substances has become a phenomenon of great importance because it affects air, water and soil, also disturbing all the ecosystems that develop in them, including humans.

Physicochemical, nutritional, and stability aspects of a meat product (gluteus medius) enriched with encapsulated fish oil in polyelectrolyte beads containing prosopis alba exudate gum Vasile, Franco Emanuel; Romero, Ana María; Judis, Maria Alicia; Mazzobre, Maria Florencia This work explores the physicochemical, nutritional, and stability aspects of a meat product enriched with fish oil encapsulated in polyelectrolyte beads. Particularly, a non-conventional exudate gum obtained from Prosopis alba tree (G) was assessed as wall component of alginate-chitosan beads. Patty-type products based on beef (gluteus medius) and pork back fat (P) were nutritionally improved by adding free fish oil (P+FO), fish oil encapsulated in alginate-chitosan (P+ACh), or alginate-gum-chitosan (P+AChG) beads. In enriched raw products, the EPA+DHA content was increased 13 folds, and the n3/n6 ratio was 45–55% higher than control. During cooking, the encapsulates increased the oil retention (91 to 94%) respect to samples added with free oil (84%), and modulated the chromatic (∆E = 1.5–1.9) and textural properties (hardness was increased 10–50%; elasticity was reduced 40%) of the cooked meat products. In presence of G, polyunsaturated fatty acids retention was higher (99%) than in P+ACh (95%) or in P+FO (94%). Additionally, P+AChG showed the lowest oxidative damage (TBA value was 50% lower than P+FO) at the end of freeze storage (90 days at − 18 °C) and subsequent heat treatment (15 min at 200 °C). Present results showed that Prosopis alba exudate gum emerges as a novel and useful excipient for the development of polyelectrolyte encapsulation systems able to protect functional lipids in meat-based products.

Evolution of soft magnetic, mechanical and electrical properties measured simultaneously during annealing of rapidly solidified alloys Moya, Javier Alberto; Gamarra Caramella, Soledad; Berejnoi, Carlos The structure evolution of some soft magnetic metastables alloys are scanned and studied through some room temperature properties changes employing only one sample submitted to successive heat treatments. These are monitored by changes occurring in room temperature magnetic properties (data obtained from hysteresis loop at 50 Hz and relative permeability at 10 kHz), room and high temperature electrical resistance and dilatometric measurements, all taken simultaneously. The method is applied to study and compare the structural evolution steps towards the most desirable soft magnetic properties of three different soft magnetic alloys of our production: an amorphous alloy of composition Fe 81 B 14 Si 5 , and two nanocrystalline, a Finemet™ (Fe 73.5 Si 16.5 B 6 Cu 1 Nb 3 ) and a Nanomet™ (Fe 81 Si 6 P 4 Cu 1 B 8 ) – type alloys. The technique reproduces the results obtained by traditional methods, and has the advantage of using fewer measuring instruments, sample tests, less time and human resources. In addition, all the experimental data present a high level of detail. With the results obtained, a large quantity of magnetic, electrical and dilatometric data is available to discern the possible applications of these three materials.

Neutron spectrometry of the 9Be(d (1.45 MeV), n)10B reaction for accelerator-based BNCT Capoulat, Maria Eugenia; Sauzet, N.; Valda, Alejandro; Gagetti, Leonardo; Guillaudin, Olivier; Lebreton, Lena; Maire, D.; Mastinu, Pierfrancesco F.; Praena, Javier; Riffard, Q.; Tampón, Benjamín; Santos, Daniel; Kreiner, Andres Juan The 9 Be(d,n) 10 B reaction was proposed in the past as a neutron source for Accelerator-Based Boron Neutron Capture Therapy. Based on numerical models and scarce experimental information about the neutron spectra, it was proven that low energy deuterons on a thin target may provide neutron beams of therapeutic quality. In particular, an 8–9 μm target bombarded by 1.45 MeV deuterons presents itself as a convenient option. The aim of this work is to provide experimental validation to these numerical models. For this purpose, neutron spectra at 0°, 35°, 60°, 90° and 123° from a (9 ± 1) μm 9 Be target were measured at the CN accelerator of the Laboratori Nazionali di Legnaro. A micro-time projection chamber (μ-TPC) was used as a neutron spectrometer.

Phase separation and emergence of collective motion in a one-dimensional system of active particles Barberis, Lucas Miguel; Peruani San Román, Fernando Miguel We study numerically a one-dimensional system of self-propelled particles, where the state of the particles is given by their moving direction (left or right), which is encoded by a spin-like variable, and their position. Particles interact by short-ranged, spring-like attractive forces and do not possess spin-spin interactions (i.e., velocity alignment). Newton's third law is broken in this model by assuming an asymmetric interaction range that is larger in the direction of the moving direction of the particle. We show that in this nonequilibrium system, due to the absence of the action-reaction symmetry, there exists an intimate link between phase separation and the formation of highly coherent, spatially localized, moving flocks (i.e., collective motion). More specifically, we prove the existence of two fundamentally different types of active phase separation, which we refer to as neutral phase separation (NPS) and polar phase separation. Furthermore, we indicate that NPS is subdivided in two classes with distinct critical exponents. These results are of key importance to understand that in active matter, there exist several phase-separation classes and that the emergence of polar, self-organized patterns (i.e., flocks) does not require the presence of a velocity alignment.