Impact of age at first calving on performance and economics in commercial dairy herds in Argentina Turiello, María Paula; Vissio, Claudina; Heinrichs, Arlyn Jud; Issaly, Liliana Cristina; Larriestra, Alejandro Jose Dairy herd efficiency depends on an adequate replacement program, and one of the main management factors affecting the replacement cost is age at first calving (AFC). The primary objective of this study was to evaluate the impact of AFC on performance and economic results in commercial dairy herds in Argentina. A retrospective study was conducted to analyze data from a total of 26,614 first lactation cows from 290 argentinian dairy farms calved for the first time during the calendar year 2016. Milk yield for first lactation cows having at least 5 milk test days was used to analyze production (n=15,181). Records were stratified by AFC into 5 groups: 1) 18–21 mo (n=202), 2) 22-25 mo (n=5,569), 3) 26-29 mo (n=5,579), 4) 30-33 mo (n=2,389), 5) 34-37 mo (n=1,442). The overall median of AFC was 27 mo. Although milk yield at the beginning of the lactation was lower for lower AFC categories, the differences between categories 2, 3, and 4 disappeared by the fourth test day at approximately 113 days in milk. No effect of AFC category was detected for milk fat and protein content and for SCC. Considering AFC categories, cows calving for the first time at 22–25 mo of age needed the shortest period after calving to conceive. The lower income associated with the mild milk losses may be compensated by the cost of more than 80 extra d in the rearing period and the increment in days open estimated for the upper categories.

Franҫoise Perus: la crítica materialista en la “crisis del tiempo”; Franҫoise Perus: materialist criticism in the “crisis of time” Kozel, Gabriel Andrés El artículo aborda la obra de Franҫoise Perus, crítica literaria de origen francés radicada en América Latina desde hace más de medio siglo. Busca ofrecer respuestas a tres interrogantes: 1) cómo convendría periodizar y organizar su obra; 2) cuáles son sus principales aportes teóricos; 3) qué intersecciones cabe perfilar entre tales aportes y el estudio de elaboraciones textuales no ficcionales, como el ensayo de ideas. Los tres interrogantes se inscriben dentro de una pregunta más amplia relativa al procesamiento de la crisis del tiempo (Hartog) por parte de la intelectualidad latinoamericana contemporánea, en la convicción de que en la obra de Perus se encuentra una modulación singularmente lúcida y coherente de esa compleja experiencia.; This article deals with the work of Franҫoise Perus, French literary critic established in Latin America for more than half a century. It seeks to put forward answers to three questions: 1) how should we organize her work in periods; 2) what its main theoretical contributions are; 3) what intersections can be outlined between such contributions and the study of non-fictional textual elaborations, such as the “essay of ideas”. These questions are situated as part of a broader one that pertains to the processing of the “time crisis” (Hartog) by the contemporary Latin American intellectuality. They also stem from the conviction that there is in Perus a singularly lucid and coherent modulation of that complex experience,

Heterologous microsatellite primers are informative for paca (Cuniculus paca), a large rodent with economic and ecological importance Roldán Gallardo, Franco Fabián; Dematteo, Karen; Rinas, Miguel Angel; Argüelles, Carina Francisca Objective: This study was designed to facilitate genetic studies that would allow information on population structure and genetic diversity of natural or captive stocks of paca (Cuniculus paca), a species of ecological and socioeconomic importance, by testing cross-amplification of 20 heterologous microsatellite primer pairs developed for guinea pigs (Cavia porcellus) and capybara (Hydrochoerus hydrochaeris). Results: Those primers that showed the best amplification profile in blood samples were subsequently applied to scats and saliva samples, to evaluate their efficiency. Of the 13 microsatellite pairs that amplified in blood, one-third (32%) were successfully amplified in saliva and scat samples. This initial work demonstrates successful cross-amplification in paca providing a solid and promising foundation for future genetic studies with this species. The ability to quantify genetic diversity using noninvasive samples from free-ranging paca is essential to developing applied management strategies for this large neotropical rodent that is not only a prey favored by wide-ranging carnivores [e.g., jaguar (Panthera onca), puma (Puma concolor)], but is also a species targeted by illegal hunting and wildlife trade.

Las leyes divinas del tiempo y del espacio: Historicismo, política y temporalidad en el discurso del joven Alberdi; The divine laws of time and space: Historicism, politics and temporality in the speech of the young Alberdi Wasserman, Fabio Enrique El trabajo reconstruye y examina la conceptualización de la temporalidad como tiempo histórico que forjaron los jóvenes románticos de la Generación del 37 y, a la vez, analiza cómo influyó en su interpretación del estado sociopolítico y en sus intervenciones en la vida pública rioplatense entre fines de la década de 1830 y comienzos de la de 1840. El foco está puesto en la obra y en la actuación de Juan Bautista Alberdi, dada la importancia y visibilidad que alcanzó en esos años y por haber sido dentro del grupo romántico quien mejor desarrolló esta novedosa concepción del tiempo de cuño historicista.; The paper reconstructs and examines the conceptualization of temporality as historical time developed by the young romantics of the Generation of 37 and, at the same time, analyzes how it influenced their interpretation of the socio-political state and their interventions in Rioplatense public life between the late 1830s and early 1840s. The focus is on the work and performance of Juan Bautista Alberdi, given the importance and visibility he achieved in those years and for having been the one who best developed within the romantics this novel conception of historicist time.

Removal of microcystin-LR and other water pollutants using sand coated with bio-optimized carbon submicron particles: Graphene oxide and reduced graphene oxide Kumar, Pratik; Pérez, José Alberto Espejel; Cledón, Maximiliano; Brar, Satinder Kaur; Duy, Sung Vo; Sauvé, Sébastien; Knystautas, Émile Sand is the most used filter adsorbent material in a drinking water treatment plant (DWTP) or household purpose filters. However, sand poses challenge for the micropollutant removal in presence of metals, natural organic matter, total organic carbon, ammonia and other macro-pollutants. In this study, sand was coated using laboratory-synthesized graphene oxide (GO) and reduced graphene oxide (rGO) to enhance its surface properties in terms of hydrophobicity, roughness and specific surface area (6 times higher for GO/rGO as compared to 5.5 m2/g for sand), that allowed an enhanced adsorption of macro pollutants as well as one target micropollutant: Microcystin-LR (MC-LR). A more electropositive surface than sand (zeta potential: −43.2 mV) in form of iron oxide-coated sand (IOCS or Fe: −21.2 mV) and its combination with GO (FeGO: −13.4 mV) was tested to validate the hypothesis of enhanced MC-LR adsorption due to electrostatic attraction. Two known MC-LR degraders (Arthrobacter ramosus and Bacillus sp.) were screened before bioaugmentation, based on the biofilm forming potential for each coated sand composite. Additionally, the dosage of GO and rGO were bio-optimized before coating them over the sand grains (400 mg/L for GO and 520 mg/L for rGO), to obtain a non-toxic and non-disruptive effect and providing at least 60% cell viability. A highest MC-LR removal of 91% was obtained under biodegradation phase using rGO-coated sand that showed an increase of 47.2% in MC-LR removal when compared to physical adsorption phase. Sand filter (control) showed a maximum MC-LR removal of 54.7%. The highest saturation adsorbent constants of 8.5 mg/kg and 7.4 mg/kg were obtained for GO and rGO-coated sand media, respectively, which was 5–6 times higher than the uncoated sand.

Gender-neutral donor deferral policies: experience in Argentina implementing individual risk-assessment policies Blanco, Sebastian; Carrizo, Luis Horacio; Moyano, Rolando Walter; Mangeaud, Arnaldo; Gallego, Sandra Veronica Background: In Argentina, with the aim of moving to a safe supportive and inclusive National Blood System, in September 2015 the Ministry of Health stipulated that eligibility criteria for blood donation should only take into account the so-called 'risk practices', focusing on a 'gender-neutral' policy. The aim of this study is to demonstrate the impact of such regulation on the prevalence of STI in the population of blood donors in Argentina, through the analysis of the scientific evidence obtained from 174 074 donors from a large central region of the country, focused on a regional Blood Bank for a 6-year period (pre- and post-entry into force of the regulations). Materials and Methods: To analyse the evolution of prevalence rates of STI, two periods of 3 years each were evaluated: The first period (P1) lasted from 16 September 2012 to 15 September 2015 (prior to the entry into force of the law) and the second one (P2) from 16 September 2015 to 15 September 2018 (after the entry into force of the law). Results: A total of 82 838 subjects were enrolled in P1 and 91 236 in P2. The results show a significantly lower prevalence of HCV (P = 0·029), HBV (P = 0·028) and syphilis (P = 0·001) in P2, while no difference was observed for HIV infection (P = 0·60). Conclusion: This study evidenced that the implementation of a 'gender-neutral' policy based on individual risk-assessment deferral criteria maintained the safety of blood supply and decreased the prevalence of STI among blood donors.

Supplementation with Resveratrol, Piperine and Alpha-Tocopherol Decreases Chronic Inflammation in a Cluster of Older Adults with Metabolic Syndrome Pastor, Raul Francisco; Repetto, Marisa Gabriela; Lairion, Fabiana; Lazarowski, Alberto; Merelli, Amalia; Manfredi Carabetti, Zulma; Pastor, Isabel; Pastor, Elena; Iermoli, Laura Valeria; Bavasso, Carlos Amadeo; Iermoli, Roberto Héctor Metabolic Syndrome (MetS) is increasing worldwide regardless of culture, genetic, gender, and geographic differences. While multiple individual risk factors, such as obesity, hypertension, diabetes, and hyperlipidemia, can cause cardiovascular disease (CVD), it is the intercurrence of these risk factors that defines MetS as a cluster that creates an environment for atherosclerosis and other manifestations of CVD. Despite the advances in the knowledge and management of each of the components of MetS, there are two molecular biology processes, chronic inflammation and oxidative stress, which are still underdiagnosed and undertreated. In order to assess the effect of a dietary supplement on chronic inflammation in MetS, we conducted a clinical trial with volunteers receiving a formula composed of resveratrol, piperine and alpha tocopherol (FRAMINTROL®), together with their habitual treatment, for three months. The inflammatory state was evaluated by ultrasensitive C reactive protein (US CRP) and ferritin in plasma, and oxygen consumption and chemiluminescence in neutrophils. The results showed that ferritin decreased by 10% (p < 0.05), US-CRP by 33% (p < 0.0001), oxygen consumption by 55% (p < 0.0001), and spontaneous chemiluminiscence was by 25% (p < 0.005) after treatment. As far as we know, this is the first study showing a chronic inflammation decrease in MetS patients due to the administration of a biopower Resveratrol-piperine and alpha tocopherol dietary supplement together with conventional therapy.

Alteridad, filosofía y creación artística: una mirada bajtiniana; Otherness, philosophy and artistic creation: a Bakhtinian look Wagon, María Elena El problema del Otro es un cuestionamiento relativamente nuevo en el terreno filosófico, pues no forma parte del origen griego de la filosofía occidental sino que se constituye como pregunta filosófica recién en la Modernidad. Este artículo pretende ahondar en la problemática de la alteridad, reflexionando sobre la forma en que dicha temática ha sido abordada por parte de la filosofía occidental. A tal efecto, se hace eco del aporte de Lévinas, quien considera que desde sus orígenes en la filosofía occidental ha primado la ontología por sobre la ética, y, en consecuencia, el concepto por sobre la individualidad. En el acto de conceptualización y objetivación del mundo por parte del Yo se neutraliza la alteridad del Otro y se lo convierte en Mismidad. Ahora bien, no obstante retomar la propuesta lévinasiana, en este trabajo se plantea que la cuestión fundamental que provoca la ausencia del Otro en el discurso filosófico es la falta de conexión entre el plano teórico de la cultura y la esfera práctica de la vida, espacio exclusivo donde se da el encuentro/choque entre el Yo y el Otro. Teniendo en cuenta esto, se deja parcialmente de lado el aporte lévinasiano, para analizar la propuesta filosófica de Mijaíl Bajtín, quien remarca que la gran falencia de la filosofía es no poder establecer un contacto directo entre el ámbito abstracto y universal en el que actúa y la singularidad de la vida práctica del ser humano. La originalidad de este trabajo está dada por la fundamentación de la sentencia lévinasiana por medio de la propuesta teórica de Bajtín.; The problem of the Other is a relatively new questioning in the philosophical field, since it is not part of the Greek origin of Western philosophy, but it is constituted as a philosophical question only in Modernity. This research aims to delve into the problem of otherness, reflecting on the way in which this subject has been addressed by Western philosophy. To this end, he echoes the contribution of Lévinas, who considers that from its origins in western philosophy, ontology has prevailed over ethics, and, consequently, the concept over individuality. In the act of conceptualization and objectification of the world on the part of the Self, the alterity of the Other is neutralized and becomes Mismity. Now, despite taking up the Levinasian proposal, in this work it is stated that the fundamental question that causes the absence of the Other in philosophical discourse is the lack of connection between the theoretical plane of culture and the practical sphere of life, space exclusive where the encounter / clash between the Self and the Other occurs. Taking this into account, the Levinasian contribution is partially set aside, to analyze the philosophical proposal of Mikhail Bakhtin, who remarks that the great flaw of philosophy is not being able to establish direct contact between the abstract and universal sphere in which it operates and the singularity of the practical life of the human being. The originality of this work is given by the foundation of the Levinasian sentence through Bakhtin's theoretical proposal.

SENSEI: Direct-Detection Results on sub-GeV Dark Matter from a New Skipper CCD Barak, Liron; Bloch, Itay M.; Cababie, Mariano Ruben; Cancelo, Gustavo Indalecio; Chaplinsky, Luke; Chierchie, Fernando; Crisler, Michael; Drlica Wagner, Alex; Essig, Rouven; Estrada, Juan; Etzion, Erez; Fernández Moroni, Guillermo; Gift, Daniel; Munagavalasa, Sravan; Orly, Aviv; Rodrigues, Dario; Singal, Aman; Sofo Haro, Miguel Francisco; Stefanazzi, Leandro; Tiffenberg, Javier Sebastian; Uemura, Sho; Volansky, Tomer; Yu, Tien Tien; SENSEI collaboration We present the first direct-detection search for sub-GeV dark matter using a new ∼2-gram high-resistivity Skipper CCD from a dedicated fabrication batch that was optimized for dark matter searches. Using 24 days of data acquired in the MINOS cavern at the Fermi National Accelerator Laboratory, we measure the lowest rates in silicon detectors of events containing one, two, three, or four electrons, and achieve world-leading sensitivity for a large range of sub-GeV dark matter masses. Data taken with different thicknesses of the detector shield suggest a correlation between the rate of high-energy tracks and the rate of single-electron events previously classified as "dark current."We detail key characteristics of the new Skipper CCDs, which augur well for the planned construction of the ∼100-gram SENSEI experiment at SNOLAB.

Wide axial-ratio bandwidth crossed dipole RFID antenna Peruzzi, Victor M.; Masson, Favio Roman; Mandolesi, Pablo Sergio; Perotoni, Marcelo B. A circularly polarised RFID tag antenna with wide axial ratio bandwidth, wide impedance bandwidth and simple tuning network is presented. The antenna, based on the widely used crossed-dipole design, incorporates a novel matching network based on two large L-shaped strips joining the arms of the dipoles to match the impedance. The L-shaped strips create large area loops enabling the antenna to be adapted to the high inductances required for good matching without the currents flowing through them degrading the axial ratio of the antenna. The gain pattern, input impedance and axial ratio (AR) are computed with numerical simulation and measurements, resulting in a 30 MHz bandwidth based on the −3 dB Axial Ratio criterion, which can provide a maximum reading distance of 12.8 m.

Raptor Entanglement with Human Debris at Nests: A Patchy and Species-Specific Problem Mallet, Julieta; Liébana, María Soledad; Santillán, Miguel Ángel; Grande, Juan Manuel Several species of birds, including raptors, add man-made objects, stones, greenplants, skins and dung of animals to build and decorate their nests. However, there is a compromise between the use of new nesting material and the increased risk of nestling mortality due to entanglement or ingestion of debris. Here, we present a compilation of cases of entanglement in raptors and specifically in a very common but poorly studied South American raptor. We observed the decoration in 86 of 95 (90,5%) nests of Southern Caracara (Caracara plancus) in an agricultural area of La Pampa province. Caracaras mainly incorporated agricultural twine in their nests and nestlings sometimes got entangled and died. We found 2 occurrences of entanglement during nine years of study. Decorating the nest, or at least to lean its interior with nylon twine, can impose a relevant death toll to Southern Caracaras, as has been found in other species elsewhere. Extension campaigns to reduce the misuse and the final disposal of debris materials such as baling twine in agricultural landscapes will be required to reduce this anthropic source of mortality in a species that although still common, is apparently reducing its numbers with the expansion of intensive agriculture.

Multiple thermochronometers applied to the quantitative analysis of compressive systems: The southern sub-Andean fold and thrust belt of Bolivia: From source rock to trap Hernandez, Juan I.; Hernández, Roberto M.; Dalenz Farjat, Alejandra; Cristallini, Ernesto Osvaldo; Alvarez, Luis A.; Dellmans, Luis M.; Costilla, Marcos Roberto; Alvarez, Andres F.; Becchio, Raul Alberto; Bordese, Sofia; Arzadún, Guadalupe; Guibaldo, Cristina; Glasmacher, Ulrich A.; Tomezzoli, Renata Nela; Stockli, Daniel F.; Fuentes, Facundo; Soria Galvarro, Jaime; Rosales, Adolfo; Dzelalija, Francisco; Haring, Claudio The evolution of fold and thrust belts requires time data restrictions to determine the rates related to the interaction of surface and subsurface processes and to quantify the time relationship between the components of the petroleum system: reservoir, seal, source rock and trap. The sub-Andean fold-and-thrust belt in the Bolivian territory in general, and the regional transect that links the structures of Curuyuqui-Carohuaicho-Tatarenda-Borebigua-Charagua and Mandeyapecua in particular, constitutes a complex multi-variable system in which the definition of time-Temperature (t-T) trajectories has led to new suitable structural and stratigraphic conclusions. The integration of multiple thermochronological-geochronological systems (Apatite Fission Track, Apatite (U-Th-Sm)/He and UPb SHRIMP on zircon) and the existing surface and subsurface geological constraints made it possible to develop a chrono-kinematic characterization of fault-related anticlines, defining their formation chronology, structural growth rate and link between them in the study area. Furthermore, it was also possible to perform a quantitative analysis of the subsidence-burial and exhumation-erosion phenomena that occurred from the deposition of Silurian-Devonian source rocks to the present time, providing relevant determinations to the modeling of the Oil & Gas system.

Profilicollis chasmagnathi (Acanthocephala) parasitizing freshwater fishes: paratenicity and an exception to the phylogenetic conservatism of the genus? Levy, Eugenia; Rossin, Maria Alejandra; Braicovich, Paola Elizabeth; Timi, Juan Tomas Polymorphid acanthocephalans are parasites of marine mammals, waterfowl and ichthyophagous birds. Among these, the genus Profilicollis is known to use exclusively decapods as intermediate hosts. Here, we report the first record of living cystacanths of Profilicollis parasitizing the body cavity of a fish host, Oligosarcus jenynsii, inhabiting the freshwater section of an estuarial system, Mar Chiquita coastal lagoon, in south-east Buenos Aires Province, Argentina. In this environment, cystacanths of Profilicollis chasmagnathi have been previously recorded infecting decapod crabs and as transient accidental infections in the gut of some carcinophagous fishes. In the present study, larvae from the crab Neohelice granulata, from the intestine of the estuarine fish Odontesthes argentinensis and from the body cavity of O. jenynsii were morphologically and genetically compared, confirming their identity as P. chasmagnathi, a species characteristic of estuaries and marine coasts along Argentina, Uruguay and Chile. These findings can be interpreted as a possible case of incipient paratenicity for Profilicollis, and a colonization event of freshwater habitats, probably promoted by the highly variable conditions, typical of ecotonal environments. In addition, cystacanths of the genus Polymorphus were also found in O. jenynsii, representing the first record of this genus in Oligosarcus from Argentina.

The diet of the Patagonian toothfish Dissostichus eleginoides, a deep-sea top predator off Southwest Atlantic Ocean Troccoli, Gonzalo Horacio; Aguilar, Eduardo; Martínez, Patricia Alejandra; Belleggia, Mauro The present study is a valuable contribution to the knowledge of feeding habits of Patagonian toothfish Dissostichus eleginoides in Southwestern Atlantic (53–55°S, 351 to 1073 m depth) near Burdwood Bank/Namuncurá marine-protected area, where diet has not been previously investigated. Based on stomach content analyses of 441 specimens ranging from 38 to 190 cm total length (TL), our study tested the hypotheses that diet was influenced by TL, sex, maturity stage, depth, and region, using generalized linear models and information theory selection criteria. The Patagonian toothfish fed primarily on fish (morid cod Notophycis marginata, myctophids, rattails Macrourus holotrachys and Coelorinchus fasciatus, notothenids Patagonotothen ramsayi, and hoki Macruronus magellanicus), followed by cephalopods (Onykia ingens, Doryteuthis gahi) and shrimps (Acanthephyra pelagica). One case of cannibalism was recorded. The trophic level was 4.57 (4.22 juveniles, 4.78 adults). The pelagic fish and bathypelagic shrimp were more consumed in the east region, whereas demersal fish and cephalopods were more consumed in the west one. Ontogenetic dietary changes associated with TL and maturity stage were reported: pelagic fish and shrimp A. pelagica had the main importance in the diet of intermediate-sized toothfish, reinforcing the hypothesis that juveniles exhibited a bento-pelagic behavior. Demersal fish were more heavily consumed by juvenile specimens, and the size of demersal fish predated by Patagonian toothfish increased according to the predator TL. Cephalopods were more consumed by adults. The preference of sexually mature specimens for cephalopods could have a positive effect on spawning and egg quality.

Effect of blend composition and related morphology on the quasi-static fracture performance of LLDPE/PP blends Rosales, Caren Soledad; Bernal, Celina Raquel; Pettarin, Valeria In the present work, the effect of composition and related morphology on the fracture behavior of LLDPE/PP blends was thoroughly investigated. Fracture behaviors evaluated under quasi-static loading conditions and different fracture mechanics methodologies were applied to assess fracture toughness depending on the materials behavior. For pure PP and 2575 blend, J at instability was chosen whereas for blends which exhibited completely ductile behavior (such as LLDPE, 7525 and 5050), the EWF methodology was used. Fracture mechanisms were elucidated with the aid of scanning electron microscopy, and results correlated with blends morphology. It was observed that fracture properties are mostly dominated by the majority component properties. In addition, for the 5050 blend, the presence of a co-continuous morphology is responsible for the high scatter of experimental data obtained.

A New Species of Haimbachia Dyar (Pyraloidea: Crambidae: Crambinae) Feeding on Spartina Schreb. (Spartinaceae) from Argentina Solis, M. Alma; Canepuccia, Alejandro Daniel; Farina, Juan Luis; Iribarne, Oscar Osvaldo A new crambid moth, Haimbachia spartina Solis and Canepuccia, new species is described from Argentina and images of the adults and their genitalia are provided. The larvae were discovered feeding on species of saltmarsh cordgrass or Spartina Schreb. (Spartinaceae). This is the first description and illustration of a Haimbachia Dyar larva. Twelve species have been described in the Western Hemisphere, but only Haimbachia maroniella Dyar and Heinrich, has been previously described from South America. The new species is compared to H. maroniella and images are provided of its type specimen, labels, and male genitalia.

A review of the critics of invasion biology Cassini, Marcelo Hernan Herein, I review existing criticisms of the field of invasion biology. Firstly, I identifiy problems of conceptual weaknesses,including disagreements regarding: (i) definitions of invasive, impact, and pristine conditions, and (ii) ecological assumptionssuch as species equilibrium, niche saturation, and climax communities. Secondly, I discuss methodological problemsinclude the misuse of correlations, biases in impact reviews and risk assessment, and difficulties in predicting theeffects of species introductions or eradications. Finally, I analyse the social conflict regarding invasive species managementand differences in moral and philosophical foundations. I discuss the recent emergence of alternatives to traditionalinvasion biology approaches, including the concept of novel ecosystems, conciliation biology, and compassionate conservation.Understanding different value systems will be the first step to reconciling the different perspectives related to thiscontroversial topic.

Redescription of Promecostethus unifalculatus, the only known harvestman from Crozet Islands (Opiliones: Triaenonychidae) Lourenco Porto, Willians; Pérez González, Abel Promecostethus unifalculatus Enderlein, 1909, is the only representative of the order Opiliones from the Crozet Islands. The species belongs to the family Triaenonychidae and is biogeographically interesting because it is a candidate for transoceanic dispersal, a very rare event in this ancient family. Despite this significance, P. unifalculatus is taxonomically still poorly known, and a redescription of this species using modern taxonomic standards is urgently needed. Here we redescribe the species, offer the first description and illustrations of the male genitalia and provide a full exomorphological survey of the species using scanning electron microscopy. Furthermore, we provide an emended diagnosis for the genus Promecostethus and discuss its relationship with some morphologically similar genera.

Clinical uses of 5-aminolaevulinic acid in photodynamic treatment and photodetection of cancer: A review Casas, Adriana Gabriela ALA-mediated Photodynamic Therapy (ALA-PDT) is one of the most promising fields in Photodynamic therapy (PDT) research for cancer treatment. 5-aminolaevulinic acid (ALA) is the prodrug of the photosensitiser Protoporphyrin IX (PpIX). After ALA administration, cells generate PpIX through the haem biosynthetic pathway. Although the exact reasons for ALA/PpIX selectivity are unknown, it is believed that due to the special regulation of haem enzymes, PpIX is accumulated in the tumours. Both ALA and its derivative ALA Methyl ester, are mainly used in dermatology. Besides, ALA-PDT has been employed for palliative and even curative treatment of endoscopically accessible tumours. Lung, oesophagus, gastric and bladder carcinomas, and also oral premalignant lesions, gynaecological intraepithelial neoplasias and Barrett's oesophagus are the conditions mostly treated with ALA-PDT. However, due to the limited penetration of ALA and light, non-dermatologic uses of ALA-PDT have not moved beyond phase I clinical trials. On the other hand, ALA-induced PpIX fluorescence is successfully employed for the Photodynamic Diagnosis (PDD) or assistance in cytoreductive surgery (Fluorescence-guided Resection, FGR). ALA has been approved for the FGR of high-grade gliomas and ALA Hexyl ester, for fluorescence cystoscopy in the diagnosis of bladder cancer. ALA-FGR is currently applied in brain, bladder, lung, colon cancers, etc. and ALA-PDD for oral premalignancies, gynaecological intraepithelial lesions and peritoneal metastases, among others. Besides, PDT can be applied concomitantly in the same diagnostic procedure. This review aimed to analyse the state of the art of clinical uses of ALA in the areas of treatment and detection in the non-dermatologic oncology fields.

Primer registro de basura en heces de puma (Puma concolor) en el Parque Nacional Los Glaciares, provincia de Santa Cruz, República Argentina Bartolucci, Cristina; Guerisoli, Maria de Las Mercedes; Martin, Gabriel Mario En este trabajo reportamos el hallazgo de restos de basura en heces de puma en el Parque Nacional Los Glaciares (PNLG), provincia de Santa Cruz (República Argentina). Los residuos fueron encontrados en tres heces de puma colectadas en los senderos de trekking dentro del PNLG, e incluyeron los siguientes ítems: hilo, fósforos y dos tipos de polietileno. A partir de estos resultados se recomienda continuar con el análisis de heces de puma e incorporar las de otros carnívoros presentes en el PNLG, para tener más elementos que permitan evaluar si se trata de un consumo accidental o si están cambiando algunos hábitos alimenticios.; In this work we report the finding of waste remains in puma feces in Los Glaciares National Park (LGNP), Santa Cruz province (Argentina). The residues were found in three puma feces collected on the trekking trails within the Park, and included the following items: thread, matches and two types of polyethylene. We recommend continuing with the analysis of puma feces, while incorporating samples from other carnivore species present in the park. This information will allow discerning whether animals are changing their feeding habits or if events like these are part of accidental consumption.