Zinc porphyrin/mesoporous titania thin film electrodes: A hybrid material nanoarchitecture for photocatalytic reduction
Caraballo, Rolando Manuel; Vensaus, Priscila; Herrera, Facundo; Soler Illia, Galo Juan de Avila Arturo; Hamer, Mariana
In this work, photocatalytic reduction of methyl viologen is achieved using zinc tetra(4-N-methylpyridyl)porphine (ZnP) functionalized mesoporous titania thin films (MTTF). Metalloporphyrins are the core of natural systems that harvest energy from the sun. Thus, a bioinspired approach is used, taking advantage of ZnP sensitizing capabilities and MTTF organized structure.
¿Por qué importa la interseccionalidad en el trabajo judicial?: Anotaciones ius feministas; Why does intersectionality matter in judicial work?: Ius feminist annotations
Lerussi, Romina Carla
En las primeras dos décadas de este nuevo siglo hemos visto un progresivo interés por parte de las instituciones judiciales latinoamericanas en introducir enfoques interseccionales de derechos humanos en el trabajo judicial. Este interés se sitúa en el marco de la elaboración de documentos jurídicos internacionales que se han transformado en requisitos normativos más o menos vinculantes según el lugar. Y, a su vez, este interés tiene sus fuentes en la teoría y praxis colectiva de movimientos feministas, disidentes y de derechos humanos y en la propia dinámica de incidencia en la acción legislativa y en el sistema judicial. Esto ha traído aparejado una serie de problemas hermenéuticos de mayor o menor gravedad referidos a las categorías y a los enfoques de dichos instrumentos legales para pasar de la mera enunciación formal a transformarse en herramientas de trabajo e interpretación judicial. En el presente texto presento una serie de dilemas epistémicos que atraviesan a la categoría de interseccionalidad en el derecho como imposibilidad. Luego, repongo razones desde la teoría feminista del derecho para abrirla como posibilidad a partir de la categoría de experiencia interseccional de Crenshaw (1989). Finalmente, sitúo esta labor en el trabajo judicial en tres niveles que quizás pueden abonar a una justicia feminista interseccional, si es que esto fuera posible.; In the fi rst two decades of this new century, we have seen a progressive interest in judicial institutions of Latin America about introducing intersectional approaches and readings of human rights in judicial work. This interest is situated within the framework of the elaboration of international legal documents that have been transformed into binding normative requirements depending on the place. And, in turn, this interest has its sources in the collective action and theory of feminist, dissident and human rights movements and in the dynamics of incidence in legislative action and in the judicial system. This has brought with it a series of hermeneutical problems of greater or lesser severity referring to the categories and approaches to go from the mere formal enunciation to becoming tools of judicial work and interpretation. In this text I present a series of epistemic dilemmas that cross the category of intersectionality in law as an impossibility. Then, I argue from feminist theory of law to open it as a possibility based on the category of intersectional experience of Crenshaw (1989). Finally, I propose three levels of praxis in judicial work that contribute to an intersectional feminist justice if this would be possible.
Transitar la cárcel y la escuela: experiencias educativas y vida cotidiana de jóvenes y adultos en las prisiones de Santa Fe (Argentina); Go through jail and school: educational experiences and daily life of youth and adults in the prisons of Santa Fe (Argentina)
Routier, Maria Eva
En el presente escrito se exponen los principales hallazgos obtenidos en el marco de una investigación desarrollada durante los años 2015-2019 cuyo objetivo fue analizar, desde una perspectiva etnográfica relacional (Rockwell, 2009; Achilli, 2010), las experiencias educativas de jóvenes y adultos varones privados de su libertad en unidades penitenciarias de la provincia de Santa Fe, en relación al conjunto de las experiencias cotidianas vividas en la cárcel. Asimismo, la intención del escrito es objetivar, mediante algunas reflexiones, las características que asumió el proceso de investigación en el tránsito de la cárcel y la escuela, como etnógrafa y como una actriz que intervino en dicho contexto mediante la participación en el desarrollo de distintos espacios socio-educativos intramuros. Para cumplir con dichos objetivos en la primera parte expondré algunos de los presupuestos iniciales de la investigación vinculados con mi “doble” inscripción en los contextos abordados, enlazados a un contexto socio-político-académico particular; así como la construcción de las herramientas conceptuales y de ciertas decisiones metodológicas y particularidades del trabajo etnográfico, en las fronteras del espacio escolar y carcelario. En la segunda partes del escrito nos detendremos en la trama de la tesis, destacando los principales núcleos problemáticos que configuran el cuerpo general del trabajo y los aportes realizados.; In this paper, the main findings obtained in the framework of a research carried out during the years 2015-2019 are exposed, the objective of which was to analyze, from a relational ethnographic perspective (Rockwell, 2009; Achilli, 2010), the educational experiences of young people and adults men deprived of their liberty in penitentiary units in the province of Santa Fe, in relation to the set of daily experiences lived in prison. Likewise, the intention of the writing is to objectify, through some reflections, the characteristics that the research process assumed in the transit of the prison and the school, as an ethnographer and as an actress who intervened in said context by participating in the development of different intramural socio-educational spaces. To meet these objectives, in the first part, I will present some of the initial assumptions of the research related to my “double” enrollment in the contexts addressed, linked to a particular socio-political-academic context; as well as the construction of conceptual tools and certain methodological decisions and particularities of ethnographic work, on the borders of the school and prison space. In the second part of the writing we will stop at the plot of the thesis, highlighting the main problematic nuclei that make up the general body of the work and the contributions made.
Las convenciones interpretativas como control horizontal de la decisión judicial; Interpretative conventions as a way of horizontal control of judicial decision
Arena, Federico José
En este trabajo propongo conectar la discusión fi- losófica sobre la práctica judicial de identificación del derecho con el problema del control de la acti- vidad judicial. Por control de la actividad judicial me refiero a la verificación de la corrección jurídica de las decisiones de jueces y juezas en sus sentencias acerca de la existencia y el contenido del derecho. Procuraré mostrar que, además de formas de control vertical, existe la posibilidad de un tipo de control horizontal apoyado en la estructura convencional que adquiere la acción colectiva de jueces y juezas. El texto se concentrará en dos cuestiones centrales: en qué consiste esa estructura convencional y de qué modo permite controlar la actividad judicial.; In this paper I intend to connect the philosophical discussion on the judicial practice of identifying the law with the problem of how to control judicial activity. By control of judicial activity I mean the verification of the legal correctness of the decisions on the existence and content of the law taken by judges in their sentences. I will try to show that, in addition to forms of vertical control, there is the possibility of a type of horizontal control based on the conventional structure that the collective action of judges acquires. The text will focus on two main issues: the elements of the conventional structure and how it may be able to control judicial activity.
Análisis de la completitud de praxeologías propuestas a estudiar en torno a la lógica en la formación de profesores de matemática; Analysis of the Completitude of Praxeologies Proposed to Study Around Logic in the Training of Mathematics Teachers
Cardona Hurtado, Oscar; Corica, Ana Rosa
En este trabajo se presentan resultados de una investigación que se ubica en la problemática de la formación de profesores en lógica matemática. Como referencial teórico se adopta a la Teoría Antropológica de lo Didáctico. La investigación se desarrolló en dos grupos de estudiantes de profesorado en matemática de una universidad colombiana. Se analizaron las prácticas de los docentes que orientaron temas relativos a cálculo proposicional y cálculo de predicados, y se examinó el material propuesto para el estudio. En particular, en este trabajo se reportan resultados del análisis del material propuesto por los docentes; se analizaron los componentes praxeológicos que se identificaron en las tareas resueltas y las tareas formuladas para ser resultas por los estudiantes. Los principales resultados de la investigación indican que tanto las tareas resueltas en el material como las tareas propuestas para su resolución, integran praxeologías con bajo grado de completitud.; In this work are presented results of an investigation that is located in the problematic of the formation of teachers in mathematical logic. As a theoretical reference, the Anthropological Theory of Didactics is adopted. The research was developed in two groups of mathematics teacher students from a Colombian university. The practices of the teachers who guided topics related to propositional calculus and predicate calculus were analyzed, and the material proposed for the study was examined. In particular, this work reports the results of the analysis of the material proposed by the teachers; the praxeological components that were identified in the solved tasks and the tasks formulated to be solved by the students were analyzed. The main results of the research indicate that both the tasks solved in the material and the tasks proposed for their resolution, integrate praxeologies with a low degree of completeness.
Immunosensor based on porous gold and reduced graphene platform for the determination of EE2 by electrochemical impedance spectroscopy
Scala Benuzzi, María Luz; Soler Illia, Galo Juan de Avila Arturo; Raba, Julio; Battaglini, Fernando; Schneider, Rudolf J.; Pereira, Sirley Vanesa; Messina, Germán Alejandro
In this work, we report an electrochemical immunosensor to detect ethinylestradiol in water samples, using electrochemical impedance spectroscopy (EIS) as a detection technique. For the development of this immunosensor, the direct modification of the working electrode of a screen-printed carbon electrode was carried out. First, to reduce the resistance of the electrode, electroreduced graphene was incorporated on the surface. Second, a porous gold structure was electrodeposited on reduced graphene by electrodeposition and the dynamic hydrogen bubble template assisted method. Thus, a marked increase in surface area was obtained for anti-EE2 antibodies immobilization. Subsequently, the specific anti-EE2 antibodies were covalently immobilized using α-lipoic acid for attaching them to the gold surface. The electrode modified with the antibodies was incubated for 30 min in the samples containing EE2, producing the specific antigen–antibody binding. As the charge transfer resistance of a redox probe in the electrode surface is governed by the surface blocking effects, the charge transfer resistance was related to the amount of EE2 captured to realize a quantitative determination. For this, the EIS measurements were performed in a 4 mM [Fe(CN)6]4−/3− solution in 0.1 M KCl. The obtained Nyquist diagrams were adjusted using the Randles circuit as an equivalent circuit to obtain the corresponding resistances. The developed methodology showed good selectivity, precision, and sensitivity; although the LOD obtained was higher than those presented in other published articles, it turned out to be an alternative that allows the determination of ethinylestradiol using a simple disposable electrode.
The throat classifier: A novel air classifier for the control of dust in manufactured sands
Petit, Andres; Irassar, Edgardo Fabián
The depletion of natural sources of sand has triggered a considerable amount of research regarding the utilization of manufactured sands in concrete production. In this context, the excess of dust in manufactured sands is a problem that needs to be solved. This work presents a novel type of air classifier called the throat classifier. The classifier was specifically designed for the removal of dust from manufactured sands. An experimental study was performed using manufactured sands with different gradations to explore the main features of the classifier. Results demonstrate that the classifier is able to improve the particle size distribution of the manufactured sands and collect the excess of dust as two additional products.
Music improvisation enhances neutral verbal and visual memory in musicians and non-musicians alike
Diaz Abrahan, Veronika Mariana; Shifres, Favio Demian; Justel, Nadia
Music is a complex activity with great cognitive potential. A specific type of research involves the use of focal music-based interventions implemented only once before, during, or after a task to improve cognitive performance. In the present research, we employed music-based interventions to explore their effects as a memory modulator. We conducted two studies: Study 1, to evaluate neutral verbal memory, and Study 2 to evaluate neutral visual memory. Volunteers, aged 18–40, participated in this investigation (124 musicians and 111 nonmusicians). After the acquisition of verbal or visual information, the volunteers were exposed to music improvisation, music imitation, or a rest condition for 3 min. We evaluated memory through free recall and recognition tasks, with immediate and deferred measures. We found a significant improvement in memory among participants involved in music improvisation, who remembered more verbal and visual information than the imitation and rest condition groups, especially in the deferred measures. We found no differences according to the musical experience. Our results reinforce the idea that music improvisation intervention modulates different types of memory.
Voces indígenas sobre "tierra adentro": una aproximación a la territorialidad fronteriza colonial en el área pampeano-norpatagónica; ndigenous voices about “tierra adentro”: an approach to colonial frontier territorialities in the Pampean-North Patagonian area
Enrique, Laura Aylen
Las extensas llanuras que se desplegaban en la frontera hispano-indígena al sur de la ciudad de Buenos Aires fueron el ámbito de negociaciones sobre los usos de los recursos y los territorios y los sentidos otorgados a ellos por los distintos grupos sociales que se disputaban el espacio pampeano-patagónico a fines del siglo XVIII. Parte de las dificultades para conocer las características de ese "paisaje mestizo" se deben a que las voces de los grupos indígenas que habitaban la región nos llegan mediadas por la escritura de los funcionarios virreinales y viajeros que interactuaban con ellos. No obstante, podemos descubrir rastros de las territorialidades indígenas en algunos documentos coloniales que nos posibilitan aproximarnos a los modos en que se organizaba la denominada "tierra adentro". Aquí nos proponemos estudiar qué aspectos son considerados significativos en la elaboración de las declaraciones e indagar sobre su incidencia en los procesos de configuración territorial. Sostenemos que las distorsiones propias de este tipo de registro escrito -pensado para ser consultado por las autoridades hispanas- nos posibilitan acercarnos a las estrategias de uso, apropiación y significación de los territorios desplegadas por los grupos indígenas.; The vast plains that were unfolded on the Spanish-indigenous border south of the city of Buenos Aires were the area of negotiations on the use of resources and territories and the meanings given to them by the different social groups that disputed the Pampean-Patagonian space at the end of the 18th century. One of the difficulties in knowing the characteristics of this “paisaje mestizo” is due to the fact that the voices of the indigenous groups that inhabited the region reach us mediated by the writing of viceregal officials and travelers who interacted with them. However, we can discover traces of indigenous territorialities in some colonial documents that allow us to approach the ways in which the so-called “tierra adentro” was organized. In this paper, we intend to study which aspects are considered significant in the preparation of testimonial statements and inquire about their impact on territorial configuration processes. We sustain that the distortions inherent to this type of written record (intended to be consulted by Hispanic authorities) allow us to approach the strategies of use, appropriation and significance of the territories deployed by indigenous groups.
Lactic Acid Bacteria Strains Differently Modulate Gut Microbiota and Metabolic and Immunological Parameters in High-Fat Diet-Fed Mice
Fabersani Marrades, Mario Emanuel; Márquez, María Antonela; Russo, Matias Irineo; Ross, Gloria Romina; Torres, Sebastián; Fontana, Cecilia Alejandra; Puglisi, Edoardo; Medina, Roxana Beatriz; Gauffin Cano, María Paola
Background: Dietary strategies, including the use of probiotics as preventive agents that modulate the gut microbiota and regulate the function of adipose tissue, are suitable tools for the prevention or amelioration of obesity and its comorbidities. We aimed to evaluate the effect of lactic acid bacteria (LAB) with different adipo- and immuno-modulatory capacities on metabolic and immunological parameters and intestinal composition microbiota in high-fat-diet-induced in mice fed a high-fat diet Methods: Balb/c weaning male mice were fed a standard (SD) or high-fat diet (HFD) with or without supplementation with Limosilactobacillus fermentum CRL1446 (CRL1446), Lactococcus lactis CRL1434 (CRL1434), or Lacticaseibacillus casei CRL431 (CRL431) for 45 days. Biochemical and immunological parameters, white-adipose tissue histology, gut microbiota composition, and ex vivo cellular functionality (adipocytes and macrophages) were evaluated in SD and HFD mice. Results: CRL1446 and CRL1434 administration, unlike CRL431, induced significant changes in the body and adipose tissue weights and the size of adipocytes. Also, these strains caused a decrease in plasmatic glucose, cholesterol, triglycerides, leptin, TNF-α, IL-6 levels, and an increase of IL-10. The CRL1446 and CRL1434 obese adipocyte in ex vivo functionality assays showed, after LPS stimulus, a reduction in leptin secretion compared to obese control, while with CRL431, no change was observed. In macrophages from obese mice fed with CRL1446 and CRL1434, after LPS stimulus, lower levels of MCP-1, TNF-α, IL-6 compared to obese control were observed. In contrast, CRL431 did not induce modification of cytokine values. Regarding gut microbiota, all strain administration caused a decrease in Firmicutes/Bacteroidetes index and diversity. As well as, related to genus results, all strains increased, mainly the genera Alistipes, Dorea, Barnesiella, and Clostridium XIVa. CRL1446 induced a higher increase in the Lactobacillus genus during the study period. Conclusions: The tested probiotic strains differentially modulated the intestinal microbiota and metabolic/immunological parameters in high-fat-diet-induced obese mice. These results suggest that CRL1446 and CRL1434 strains could be used as adjuvant probiotics strains for nutritional treatment to obesity and overweight. At the same time, the CRL431 strain could be more beneficial in pathologies that require regulation of the immune system.
Properties of galaxies with ring structures
Fernandez, Julia; Alonso, Sol; Mesa, Valeria Alejandra; Duplancic Videla, Maria Fernanda; Coldwell Lloveras, Georgina Vanesa
Aims: We present a statistical analysis of different characteristics of ringed spiral galaxies with the aim of assessing the effects of rings on disk galaxy properties. Methods: We built a catalog of ringed galaxies from the Sloan Digital Sky Survey Data Release 14 (SDSS-DR14). Via visual inspection of SDSS images, we classified the face-on spiral galaxies brighter than g < 16.0 mag into galaxies with: an inner ring, an outer ring, a nuclear ring, both an inner and an outer ring, and a pseudo-ring. In addition to rings, we recorded morphological types and the existence of bars, lenses, and galaxy pair companions with or without interaction. With the goal of providing an appropriate quantification of the influence of rings on galaxy properties, we also constructed a suitable control sample of non-ringed galaxies with similar redshift, magnitude, morphology, and local density environment distributions to those of ringed ones. Results: We found 1868 ringed galaxies, accounting for 22% of the full sample of spiral galaxies. In addition, within galaxies with ringed structures, 46% have an inner ring, 10% an outer ring, 20% both an inner and an outer ring, 6% a nuclear ring, and 18% a partial ring. Moreover, 64% of the ringed galaxies present bars. We also found that ringed galaxies have both a lower efficiency of star formation activity and older stellar populations (as derived with the Dn(4000) spectral index) with respect to non-ringed disk objects from the control sample. Moreover, there is a significant excess of ringed galaxies with red colors. These effects are more important for ringed galaxies that have inner rings and bars with respect to their counterparts that have some other types of rings and are non-barred. The color-magnitude and color-color diagrams show that ringed galaxies are mostly concentrated in the red region, while non-ringed spiral objects are more extended to the blue zone. Galaxies with ringed structures present an excess of high metallicity values compared to non-ringed ones, which show a 12 + Log(O/H) distribution toward lower values. These findings seem to indicate that rings are peculiar structures that produce an accelerating galactic evolution, strongly altering the physical properties of their host galaxies.
Deber de memoria: El informe por entregas "Miseria de la prensa del Proceso" de la revista Humor: Periodismo, ética y denuncia en la escena postdictatorial argentina (1984); Duty of memory: The report “Miseria de la prensa del Proceso” in humor mkagazine: Press, ethics and denounce in the argentine postdictatorial scene (1984)
Raíces, Eduardo
El presente artículo analiza el informe “Miseria de la prensa del Proceso”, dedicado a denunciar las actitudes oportunistas de la prensa gráfica entre la última dictadura militar argentina (1976-1983) y la nueva etapa democrática. Fue realizado por Carlos Gabetta y Sergio Joselovsky y publicado en nueve entregas por la revista Humor durante varios meses de 1984. Se contempla el modo en que Humor se atribuyó autoridad para evaluar la conducta de los actores de prensa; el estilo y criterios de selección y cobertura de varias de las principales publicaciones de la época; y en particular las formas propuestas para evidenciar cambios en la línea editorial de los medios denunciados. Sirviéndonos del enfoque de estudios de memoria social fue posible señalar que el informe evaluó las actitudes periodísticas como “cómplices”, “victimizadas” y “heroicas”. Con ello, si bien evidenció oportunismos y resistencias, no logró dar cuenta acabada de los cambios y ambigüedades del funcionamiento mediático a lo largo del periodo. Pese a estas limitaciones, “Miseria…” supuso una estrategia de denuncia pionera durante la inmediata posdictadura de los dudosos valores democráticos de gran parte de la prensa, planteada en términos ético-profesionales y políticos desde un medio independiente con reconocimiento local e internacional.; Our essay deals with the Report “Miseria de la prensa del Proceso”, focused in denouncing opportunist attitudes by press between last Argentinean dictatorship (1976-1983) and the return of democratic régime. It was made by journalists Carlos Gabetta and Sergio Joselovsky and published in nine fascicules in Humor magazine during several months of 1984. It is Studied the way Humor self-attributed Authority to evaluate the conduct of press actors; the style and selection criteria of materials from main media of the era; and the strategies employed by Humor to put in evidence the changes in editorial line of denounced media. By using the approach of social memories studies, we stated that the Report classified press attitudes between complicity, victimization and heroism. If that classification exposed opportunist and resistant attitudes in press actors, failed to detect the changes and ambiguities of each media along the time. In spite of these limitations, we conclude that the Report involved an early strategy to denounce the apparent continuity in newspapers and magazines from dictatorship to constitutional régime and, thus, their dubious democratic values, posed in ethical-political terms by a well-known independent magazine.
El sueño, las palabras y la cosa: La filosofía de Marx frente a la Comuna; The Dream, the words and the thing: Marx’s philosophy facing the Commune
Dominguez, Esteban
En estas páginas me propongo reflexionar sobre un conjunto de cuestiones relativas a la filosofía de Marx a la luz de la experiencia de la Comuna de París. Más específicamente, quisiera señalar que la experiencia de Marx frente a la Comuna podría constituirse en un revelador de algunos trazos significativos de su filosofía. En primer lugar, propongo un análisis de la carta de Marx a Ruge en Kreuznach (1843), con el fin de reflexionar sobre la idea de la revolución que tiene el joven Marx, identificando dos pliegues críticos que la modifican y la proyectan transformada hacia la Comuna. En segundo lugar, propongo una relectura de La guerra civil en Francia (1871), atravesada por una disyunción interna entre la palabra científica, la palabra política y la palabra filosófica presentes en Marx, pero que se resisten a ser reapropiadas en un único discurso.; In this paper I aim to think about a set of different issues in relation to Marx’s philosophy on the light of the experience of Paris Commune. More specifically, I would like to point out that Marx’s experience facing the Commune could be constituted as a revealing indicator of some of the most significant outlines of his philosophy. Firstly, I am proposing an analysis of the letter from Marx to Ruge in Kreuznach (1843) with the purpose of thinking over young Marx’s revolution idea by identifying two critical aspects that modify and project it transformed towards the Commune. In second place, I present a re-reading of The Civil War in France (1871) crossed by an internal disjunction between the scientific, political and philosophical words that are present in Marx, but that resist to be reappropriated in a single speech.
Determinants of Aedes mosquito density as an indicator of arbovirus transmission risk in three sites affected by co-circulation of globally spreading arboviruses in Colombia, Ecuador and Argentina
Talbot, Benoit; Sander, Beate; Cevallos, Varsovia; González, Camila; Benítez, Denisse; Carissimo, Claudio; Carrasquilla Ferro, María C.; Gauto, Neris; Litwiñiuk, Sergio Leandro; López, Karen; Ortiz, Mario I.; Ponce, Patricio; Villota, Stephany D.; Zelaya, Fabian; Espinel, Mauricio; Wu, Jianhong; Miretti, Marcos Mateo; Kulkarni, Manisha A.
Background: The global impact of Zika virus in Latin America has drawn renewed attention to circulating mosquito-borne viruses in this region, such as dengue and chikungunya. Our objective was to assess socio-ecological factors associated with Aedes mosquito vector density as a measure of arbovirus transmission risk in three cities of potentially recent Zika virus introduction: Ibagué, Colombia; Manta, Ecuador; and Posadas, Argentina, in order to inform disease mitigation strategies. Methods: We sampled Aedes mosquito populations in a total of 1086 households, using indoor and peridomestic mosquito collection methods, including light traps, resting traps, traps equipped with chemical attractant and aspirators. For each sampled household, we collected socio-economic data using structured questionnaires and data on microenvironmental conditions using iButton data loggers. Results: A total of 3230 female Aedes mosquitoes were collected, of which 99.8% were Aedes aegypti and 0.2% were Aedes albopictus. Mean female Aedes mosquito density per household was 1.71 (standard deviation: 2.84). We used mixed-effects generalized linear Poisson regression analyses to identify predictors of Aedes density, using month, neighborhood and country as random-effects variables. Across study sites, the number of household occupants [incidence rate ratio (IRR): 1.08, 95% confidence interval (CI): 1.01–1.14], presence of entry points for mosquitoes into the household (IRR: 1.51, 95% CI: 1.30–1.76) and presence of decorative vegetation (IRR: 1.52, 95% CI: 1.22–1.88) were associated with higher Aedes density; while being in the highest wealth tertile of household wealth (IRR: 0.78, 95% CI: 0.66–0.92), knowledge of how arboviruses are transmitted (IRR: 0.94, 95% CI: 0.89–1.00) and regular emptying of water containers by occupants (IRR: 0.79, 95% CI: 0.67–0.92) were associated with lower Aedes density. Conclusions: Our study addresses the complexities of arbovirus vectors of global significance at the interface between human and mosquito populations. Our results point to several predictors of Aedes mosquito vector density in countries with co-circulation of multiple Aedes-borne viruses, and point to modifiable risk factors that may be useful for disease prevention and control.
Jóvenes y violencia policial: Posibilidades y desafíos de la entrevista cualitativa; Young people and police violence: Possibilities and challenges of the qualitative interview
Roldan, Macarena del Valle; Soloa, Emanuel; Bonvillani, Andrea
El artículo presenta los resultados de una investigación cualitativa que analizó las experiencias de violencia policial vivenciadas por jóvenes de la ciudad de Córdoba, Argentina. Se trabajó con datos producidos a partir de entrevistas no estructuradas con doce jóvenes que dieron lugar a tres tópicos de discusión: las narrativas de los jóvenes acerca del encuentro con lo policial, las construcciones de masculinidad que ponen en juego allí y la implicación del/la investigador/a en la situación de entrevista. Finalmente, se discute acerca de las posibilidades y desafíos que presenta la entrevista con estos jóvenes desde una perspectiva metodológica y ético-política.
Arnold Heim (1882-1965) geólogo-naturalista suizo: El primer Miembro correspondiente de la Sociedad Geológica Argentina
Cingolani, Carlos Alberto; Uriz, Norberto Javier; Carrasquero, Silvia Irene; Bidone, Andrea Rosa; Arnol, Jonatan Ariel
La intensa actividad geológica y de naturalista multifacético en diversas partes del mundo, convirtieron al Dr. Arnold Heim en una destacada personalidad para la época. Se formó académicamente en la escuela geológica suiza de Zúrich. Son conocidos los detallados trabajos en la Precordillera, Patagonia y otros sectores publicados durante su estadía en Sudamérica. Fue seleccionado en 1946, como el primer Miembro Correspondiente de la Sociedad Geológica Argentina. Además de la actividad en la prospección de petróleo, publicó unos 300 trabajos científicos, incluyendo descripciones de sus viajes con relatos completos de flora y fauna, y de los habitantes de la región visitada y sus costumbres. Formó parte de la primera expedición científica suiza a los Himalayas, donde realizó junto a su discípulo A. Gansser relevantes observaciones estratigráficas y tectónicas, con el descubrimiento de rocas ofiolíticas como relictos del antiguo Mar de Tethys y la interpretación de una colisión continental. Ha dejado una valiosa documentación de fotos, mapas y correspondencia preservada en la Biblioteca ETH de Zúrich. En 1939 con 57 años llega a Sudamérica, donde se siente sorprendido por la desbordante naturaleza del sur chileno-argentino. El objetivo era explorar la zona del Lago General Carrera-Buenos Aires, el Campo de Hielo Patagónico Norte y el destino final, ascender el Monte San Valentín. Luego fue contratado por la Dirección de Minas de Buenos Aires para estudios geotécnicos en San Juan y La Rioja, entre otros. Sus detallados esquemas estructurales de Barreal, Rinconada y el río San Juan, aún tienen vigencia. Fue un geólogo viajero incansable, a quien se lo llegó a conocer como el "Humboldt suizo".; The intense geological and naturalistic activity of Dr. Arnold Heim in various parts of the world, lead him to become an outstanding personality for the time. He obtained a PhD at the University of Zürich. The detailed manuscripts of the Precordillera, Patagonia and other sectors published by A. Heim during his stays in Argentina and Chile are well known. He was designed in 1946, as the first Corresponding Member of the Argentine Geological Society. In addition to his activity in oil prospecting, about 300 scientific publications are recorded; descriptions of the trips are included with complete accounts of flora and fauna and of the inhabitants of the visited regions and their customs, as well as maps and geographical works. An important milestone in his life was the possibility of being part of the first Swiss scientific expedition to the Himalayas, where he head with his disciple A. Gansser. The results were relevant stratigraphic and tectonic observations with the discovery of ophiolitic rocks of the ancient Tethys Sea and the interpretation of a continental collision. In all cases, he has left valuable documentation such as photos, maps and correspondence preserved in the ETH Bibliothek in Zürich. In 1939 with 57 years old arrived in South America. Upon arriving, he is surprised by the overwhelming nature offered by the southern Chilean-Argentine region. The initial objective of his trip was to explore the area of the Northern Patagonian Ice Field and the final destination, ascend Mount San Valentín. He was then hired by the ‘Dirección de Minas’ of Buenos Aires for various geotechnical studies in San Juan and La Rioja, among others. The detailed structural schemes of Barreal, Rinconada, and the San Juan river, are still valid. Along his life Heim was a tireless traveling geologist, who came to mention him as the “Swiss Humboldt”.
Community Mortality due to Respiratory Syncytial Virus in Argentina: Population-based surveillance study
Caballero, Mauricio Tomás; Bianchi, Alejandra Silvina; Diaz Grigaites, Sebastian; de la Iglesia Niveyro, Paola Ximena; Nuño, Alejandra; Valle, Sandra; Afarian, Gabriela; Esperante, Sebastian; Ferreti, Adrián; Jares Baglivo, Sofía; De Luca, Julián; Álvarez Paggi, Damián Jorge; Diamanti, Adriana; Bassat, Quique; Polack, Fernando Pedro
Background. Many deaths in infants from low-middle income countries (LMICs) occur at home or upon arrival to health facilities. Although acute lower respiratory tract illness plays an important role in community mortality, the accuracy of mortality rates due to respiratory syncytial virus (RSV) remains unknown.
Methods. An active surveillance study among children aged under 5 years old (U5) was performed in Buenos Aires, Argentina, between January and December 2019, to define the burden and role of RSV in childhood community mortality.
Results. A total of 63 families of children U5 participated in the study. Based on a combined approach of tissue sampling, verbal autopsies, and expert’s analysis, RSV infection was found in the causal chain of 11 from 12 cases with positive molecular biology results in respiratory samples. The estimated mortality rate due to RSV among infants was 0.27 deaths/1000 live births. The mean age of RSV-related household deaths was 2.8 months of age (standard deviation [SD] 1.7), and 8/12 were male infants (66.7%). Dying at home from RSV was associated with Streptococcus pneumoniae and/or Moraxella catarrhalis lung coinfection (75%), living in slums and settlement (odds ratio [OR], 17.09; 95% confidence interval [CI], 1.3–219.2), and other underlying comorbidities (OR, 14.87; 95% CI, 1.3–164.6).
Conclusions. Infant community mortality rates due to RSV are higher than those reported in industrialized countries and similar to those reported in hospital-based studies in the same catchment population.
An OpenFOAM Application for Solving the Black Oil Problem
Fioroni, Soledad; Larreteguy, Axel Eduardo; Savioli, Gabriela Beatriz
An OpenFOAM application to address black oil problems using the finite volume technique is presented, along with the first results of the new solver. The black oil formulation is well known in petroleum reservoir engineering and widely implemented in primary and secondary recovery processes. Simulation of three-phase flow in porous media including fluid and rock compressibility requires careful consideration in the numerical model in order to guarantee a conservative calculation. Therefore, a detailed mathematical model and its implementation, with emphasis on the numerical treatment, are presented in this work. The solver is validated over several case studies comparing its results against a semi-analytical solution and those obtained by both in house and commercial simulators reported in the literature, thus proving to successfully represent compressible and incompressible multiphase flow in porous media.
Apropiaciones historiográficas en la dramaturgia argentina de la posdictadura: los casos Raúl Dargoltz y Juan Raúl Rithner; Historiographic Appropriations in the Argentine Post-dictatorship Dramaturgy: the Raúl Dargoltz and Juan Raúl Rithner Cases
Tossi, Mauricio Antonio
En el contexto de la posdictadura argentina, las dramaturgias de la Patagonia y el Noroeste han actualizado el potencial estético del teatro histórico moderno, mediante una particular relectura del teatro documental. Así, determinadas obras de Raúl Dargoltz y Juan Raúl Rithner exponen modos específicos de apropiación de referentes historiográficos del norte y el sur del país. A pesar de sus fronteras geográficas, estas dramaturgias evidencian una solidaridad poética entre ambas regiones, al optar por la resignificación de procedimientos estéticos que, entre otros efectos, contribuyen al abordaje de interrogantes comunitarios sobre los sentidos del pasado reciente.; In the context of the Argentine post-dictatorship, the dramaturgies of Patagonia and the Northwest have updated the aesthetic potential of modern historical theater, through a particular rereading of documentary theater. Thus, certain plays by Raúl Dargoltz and Juan Raúl Rithner expose specific ways of appropriating historiographic references from the north and south of the country. Despite their geographical borders, these dramaturgies show a poetic solidarity between both regions, by opting for the resignification of aesthetic procedures that, among other effects, contribute to addressing community questions about the meanings of the recent past.
Antibody-based inhibition of pathogenic new world hemorrhagic fever mammarenaviruses by steric occlusion of the human transferrin receptor 1 apical domain
Ferrero, Sol; Flores, Maria D.; Short, Connor; Vázquez, Cecilia Alejandra; Clark, Lars E.; Ziegenbein, James; Zink, Samantha; Fuentes, Daniel; Payés, Cristian; Batto, María V.; Collazo, Michael; García, Cybele C.; Abraham, Jonathan; Cordo, Sandra Myriam; Rodriguez, Jose A.; Helguera, Gustavo Fernando
Pathogenic clade B New World mammarenaviruses (NWM) can cause Argentine, Venezuelan, Brazilian, and Bolivian hemorrhagic fevers. Sequence variability among NWM glycoproteins (GP) poses a challenge to the development of broadly neutralizing therapeutics against the entire clade of viruses. However, blockade of their shared binding site on the apical domain of human transferrin receptor 1 (hTfR1/CD71) presents an opportunity for the development of effective and broadly neutralizing therapeutics. Here, we demonstrate that the murine monoclonal antibody OKT9, which targets the apical domain of hTfR1, can sterically block cellular entry by viral particles presenting clade B NWM glycoproteins (GP1-GP2). OKT9 blockade is also effective against viral particles pseudotyped with glycoproteins of a recently identified pathogenic Sabia-like virus. With nanomolar affinity for hTfR1, the OKT9 antigen binding fragment (OKT9-Fab) sterically blocks clade B NWM-GP1s and reduces infectivity of an attenuated strain of Junin virus. Binding of OKT9 to the hTfR1 ectodomain in its soluble, dimeric state produces stable assemblies that are observable by negative-stain electron microscopy. A model of the OKT9-sTfR1 complex, informed by the known crystallographic structure of sTfR1 and a newly determined structure of the OKT9 antigen binding fragment (Fab), suggests that OKT9 and the Machupo virus GP1 share a binding site on the hTfR1 apical domain. The structural basis for this interaction presents a framework for the design and development of high-affinity, broadly acting agents targeting clade B NWMs. IMPORTANCE Pathogenic clade B NWMs cause grave infectious diseases, the South American hemorrhagic fevers. Their etiological agents are Junin (JUNV), Guanarito (GTOV), Sabiá (SABV), Machupo (MACV), Chapare (CHAV), and a new Sabiá-like (SABV-L) virus recently identified in Brazil. These are priority A pathogens due to their high infectivity and mortality, their potential for person-to-person transmission, and the limited availability of effective therapeutics and vaccines to curb their effects. While low homology between surface glycoproteins of NWMs foils efforts to develop broadly neutralizing therapies targeting NWMs, this work provides structural evidence that OKT9, a monoclonal antibody targeting a single NWM glycoprotein binding site on hTfR1, can efficiently prevent their entry into cells.