Trielectrode plasma reactor for water treatment Giuliani, Leandro Estanislao; De Angelis, L.; Díaz Bukvic, Gema; Zanini, Matías; Minotti, Fernando Oscar; Errea, María Inés; Grondona, Diana Elena Water pollution due to emerging organic pollutants, such as agrochemicals, has become a topic of growing interest worldwide. The increase of pollutants in aquatic systems stimulated the development of new strategies for water remediation. Plasma technology is an advanced oxidation process which has proved to be an efficient method for organic matter degradation. In this work, a novel design of a trielectrode plasma reactor based on a dielectric barrier discharge extended to a third electrode operated in ambient air is presented. The water to be treated flows through a gutter with low impedance and far from the electrodes connected to the voltage sources. The reactor operates in ambient air, and it does not rely on the use of expensive inert gases. The design of the reactor is easily scalable. The performance of the reactor, in terms of the removal efficiency and the energy yield, was tested in an aqueous solution of the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D), one of the most widely used around the world. The reactor presents a good efficiency in the removal of the herbicide 2,4-D and values of energy yield of about 240 mg/kW h.

Quadratic helicity and cosmological magnetic fields Akhmet'ev, Peter; Cirilo, Diego Julio; Smirnov, Alexandr In this work, the quadratic helicity χB(2) is discussed from the physical and topological points of view. We show, after the introduction of a mathematical description of the properties of helicity and quadratic helicity in the context of standard dynamo equations, examples of the importance of these high invariants in cosmological scenarios. These scenarios consider extensions of the standard model and extensions of GR.

Physics of in vitro magnetofection. Effect of magnetic transport and redistribution of nanoparticles Arciniegas Vaca, Magda Lorena; Pasquevich, Gustavo Alberto; Mykhaylyk, Olga; Mele, Nicolás Germán; Goya, Rodolfo Gustavo; Sanchez, Francisco Homero A comprehensive study of relevant aspects of the physics behind in vitro magnetic assisted transfection, or magnetofection is presented. Magnetofection experiments were performed as a function of culture-magnet distance for a fixed time of 30 min, as a function of time for a fixed separation of about 1 mm, and under special geometries chosen to elucidate the relative effects of gravitational and magnetic forces. It is shown that under appropriate conditions, in vitro magnetofection can be performed with almost equal easiness in any desired space direction, even against gravity. Redistribution of magnetic nanoparticles in a colloid, with an initial uniform distribution, was studied with the same experimental setup used in magnetofection experiments, as a function of time, and as a function of culture-magnet relative position. It was found that magnetic nanoparticles tend to arrange into concentrated regions with ring or circle shapes, and that final distribution depends strongly on relative position. Cellular uptake of magnetic nanoparticles was estimated for standard magnetofection and for no applied magnetic field experiments. A consistent description of results is given by comparing magnetofection efficiency, nanoparticles uptake and redistribution experiments. The results presented here constitute novel information that will contribute to gaining deeper understanding of how magnetofection proceeds and how can be improved. They impact directly on in vivo procedures, providing conceptual tools to optimize setup geometry and magnetic field application time.

El papel del análisis financiero en la identificación de las incertidumbres sobre empresa en marcha; The role of financial analysis in identifying uncertainties about going concern Briozzo, Anahi Eugenia; Albanese, Diana Ester; Pullés, Yanina; Di Rocco, Paula El objetivo de este trabajo es analizar empíricamente la relación de los ratios financieros y las características de la empresa, con la inclusión de un párrafo de énfasis por la incertidumbre sobre empresa en marcha en el informe del auditor. Se estudian las firmas que realizan oferta pública de sus acciones en los mercados de valores de Argentina. El análisis estadístico se realiza en dos etapas: análisis bivariado con tests no paramétricos y análisis multivariado empleando una regresión probit. Los resultados del análisis bivariado muestran que la antigüedad, la razón corriente y los ratios de endeudamiento están significativamente asociados con la incertidumbre de empresa en marcha. En el análisis multivariado son relevantes con efecto negativo el margen sobre ventas y la antigüedad, mientras que el ratio de endeudamiento muestra un efecto positivo.; The aim of this work is to empirically analyze the relationship of financial ratios and firm characteristics with the inclusion of an emphasis paragraph for uncertainty related to the going concern assumption in the auditor’s report. The firms that make public offers of their shares in the stock markets of Argentina are studied. Statistical analysis is carried out in two stages: bivariate analysis with non-parametric tests, and multivariate analysis using a probit regression. The results of the bivariate analysis show that the age of the firm, current ratio, and solvency ratios are significantly associated with the uncertainty of a going concern. In the multivariate analysis, the margin on sales and the age of the firm are relevant, with a negative effect on the likelihood of the firm having a report with an emphasis on uncertainty of a company in progress, while the debt ratio shows a positive effect.

Tulio Halperin Donghi y sus contextos, 1962 Viale, Adrián Mariano Introducción a la reedición del artículo de Tulio Halperin Donghi: "Historia y larga duración: examen de un problema".

A new megaflora (leaves and reproductive structures) from the Huancané Formation (Lower Cretaceous), Peru Martinez, Leandro Carlos Alcides; Pacheco Huacallo, Edgar; Pujana, Roberto Roman; Padula, Horacio We describe fossil leaves and reproductive structures remains from the Lower Cretaceous of Peru. A great part of the plant fossils are very well preserved, and they come from three different stratigraphic levels of the Huancane Formation in a single locality close to Cusco City. The fossil flora is dominated by Brachyphyllum, Cupressinocladus, Podozamites, leaves assigned to the Araucariaceae and Araucarites Presl. Other leaf fossil-genera found are: Weichselia, Sagenopteris, Sphenopteris, and Pachypteris. This fossil assemblage is consistent with the age inferred for the Huancane Formation, which was based on biostratigraphic and isotopic studies. The plant assemblage suggests a forest canopy dominated by conifers, with an understore composed by ferns (Weichselia) and putative pteridosperms. These new data increase the knowledge of the palaeofloristic composition of the Cretaceous flora of Peru, contribute to the fossil record of South America, and particularly to the palaeoflora near equatorial regions.

Data of ureagenesis from ammonia, glutamine and alanine, and mitochondrial aquaporin-8 expression in thioacetamide-treated hepatocytes Capiglioni, Alejo Matías; Alvarez, María de Luján; Marinelli, Raul Alberto We present data about the synthesis of urea from different substrates, i.e., free ammonia, glutamine and alanine in primary cultured rat hepatocytes treated or untreated with the model hepatotoxic agent thioacetamide (TAA). We also provide data about the expression of mitochondrial aquaporin-8 (mtAQP8), a hepatocyte channel protein which facilitates ammonia diffusion into mitochondria to supply the urea cycle. Ammonia-derived ureagenesis was significantly inhibited by about 30% while that from the both amino acids resulted unaffected in TAA-treated hepatocytes. Protein expression of mtAQP8 was decreased by about 80% after TAA treatment. These data can be useful for the understanding of the mechanisms of drug-induced hepatic dysfunction.

Further results on why a point process is effective for estimating correlation between brain regions Cifre, I.; Zarepour Nasir Abadi, Mahdi; Horovitz, S. G.; Cannas, Sergio Alejandro; Chialvo, Dante Renato Signals from brain functional magnetic resonance imaging (fMRI) can be efficiently represented by a sparse spatiotemporal point process, according to a recently introduced heuristic signal processing scheme. This approach has already been validated for relevant conditions, demonstrating that it preserves and compresses a surprisingly large fraction of the signal information. Here we investigated the conditions necessary for such an approach to succeed, as well as the underlying reasons, using real fMRI data and a simulated dataset. The results show that the key lies in the temporal correlation properties of the time series under consideration. It was found that signals with slowly decaying autocorrelations are particularly suitable for this type of compression, where inflection points contain most of the information.

Prática de atividade física, a percepção do ambiente e o perfil sociodemográfico nos diferentes distritos de saúde do SUS do município de Ribeirão Preto – SP; Practice of physical activity, a perception of the environment and the sociodemographic profile in the different SUS health districts of the city of Ribeirão Preto - SP Hodniki, Paula Parisi; Teixeira, Carla Regina de Souza; Dias, Mirele Coutinho; Lima, Rafael Aparecido Dias; Lavin Fueyo, Julieta; Binhardi, Barbara Aparecida; Istilli, Plinio Tadeu; Marques, Jennifer Vieira Paschoalin O conhecimento da percepção do ambiente das pessoas para a prática de atividade física e sua distribuição nos distritos de saúde no município contribui para o planejamento nas intervenções públicas em saúde. O objetivo do estudo foi analisar a percepção do ambiente para a prática de atividade física, e o perfil sociodemográfico dos usuários do SUS do município de Ribeirão Preto – SP, coletados nos cinco distritos de saúde da cidade. Dos 719 participantes, 71,20% são do sexo feminino e 28,80% do masculino. A maioria dos participantes tinha idade de 34 a 59 anos (40,80%), 40,80% pessoas com ensino fundamental incompleto, 51,90% das pessoas são da classe econômica C, 43,40% referiram estar com emprego e (70,10%) e apresentar DCNT. Em relação a prática de atividade física, 21,00% praticavam como deslocamento e 16,00% no lazer, em relação à recomendação. A maioria percebeu que o ambiente em relação ao acesso às conveniências, segurança no trânsito, segurança geral, apoio social para a prática de atividade física e poluição geral, era ruim ou regular. Foram encontradas diferenças na percepção do ambiente entre os distritos de saúde. Essas informações são necessárias para a elaboração de intervenções com trabalho multiprofissional para a educação em saúde. E, para repensarmos sobre o ambiente construído e políticas de incentivo e apoio social para a prática de atividade físicas das pessoas com e sem doenças crônicas que utilizam o Sistema Único de Saúde.; The knowledge of people's perception of the environment for the practice of physical activity and its distribution in health districts in the municipality contributes to the planning of public health interventions. The objective of the study was to analyze the perception of the environment for the practice of physical activity, and the sociodemographic profile of SUS users in the city of Ribeirão Preto - SP, collected in the five health districts of the city. Of the 719 participants, 71.20% are female and 28.80% are male. Most of the participants were aged between 34 and 59 years (40.80%), 40.80% people with incomplete elementary education, 51.90% of people are from economic class C, 43.40% reported having a job and (70.10%) and have CNCD. Regarding physical activity, 21.00% practiced commuting and 16.00% at leisure, in relation to the recommendation. Most realized that the environment in relation to access to conveniences, traffic safety, general safety, social support for the practice of physical activity and general pollution, was bad or regular. Differences were found in the perception of the environment between health districts. This information is necessary for the elaboration of interventions with multiprofessional work for health education. And, to rethink about the built environment and policies of incentive and social support for the practice of physical activity of people with and without chronic diseases who use the Unified Health System.

The importance of denitrification performed by nitrogen-fixing bacteria used as inoculants in South America Zilli, Jerri Édson; Alves, Bruno Jose Rodrigues; Rouws, Luc Felicianus Marie; Simões-Araujo, Jean Luiz; de Barros Soares, Luis Henrique; Cassan, Fabricio Dario; Obando Castellanos, Dolly Melissa; O'Hara, Graham Replacing synthetic fertilizers by biological nitrogen fixation (BNF) is regarded as an environmentally sound practice, but some diazotrophic bacteria are capable of emitting N2O by denitrification. The ability to use nitrate represents an ecological advantage for the survival of some microorganisms under O2-limiting conditions, but may contribute to increased N2O emissions. Scope The importance of denitrification performed by N2-fixing bacteria used as inoculants in South America is discussed, especially the possibility of these bacteria act as N2O source or sink. Conclusions There is no doubt of the importance of BNF as a sustainable N source for plants. Through genome investigation, we demonstrated that some strains widely used as inoculants for BNF harbor the entire denitrification pathway to reduce nitrate to N2. Others contain none, or only some of the denitrification genes, resulting in complete absence of denitrification or production of intermediates such as NO2−, NO or N2O. Evidence of differential effects of bacterial strains on soil N2O were reported, but more studies are still needed to affirm crop inoculation can be a driver for source or sink of this gas. Finally, considerations were made about BNF as an indispensable resource to indirectly mitigate greenhouse gas emissions in agroecosystems.

La distribución y organización del riego en San Salvador de Jujuy: Niveles de estatalidad y municipalización entre las décadas de 1860 y 1890; The distribution and organization of irrigation in San Salvador de Jujuy: Levels of statehood and municipalization between the 1860s and 1890s Hernández Aparicio, Nicolás El presente artículo se aboca al rol de la municipalidad de San Salvador de Jujuy en torno a la reglamentación y distribución del agua para riego. La aparición de ese nivel de gobierno data del año 1856, y su puesta en funcionamiento y normalización incluyó, entre otras cuestiones, los elementos normativos que aquí consideramos. Trabajos anteriores han analizado ese contexto y la problemática derivada entre los poderes provincial y municipal para legislar el recurso hídrico, en este artículo pretendemos abordar las décadas de 1860 hasta 1890, que de alguna manera estuvieron signadas por un mayor desenvolvimiento institucional aunque, como se buscará demostrar, no implicó que la municipalidad adquiriera las facultades subjetivas de mando en términos weberianos, para poder disponer de los cánones de riego y los funcionarios destinados a vigilar el reparto del agua.; This article focuses on the role of the municipality of San Salvador de Jujuy in the regulation and distribution of water for irrigation. The appearance of that level of government dates from 1856, and its implementation and standardization included, among other issues, the normative elements that we consider here. Previous work has analyzed this context and the problem derived between the provincial and municipal powers to legislate the water resource, in this article we intend to address the decades of 1860 to 1890, which were somehow marked by a greater institutional development although, as will be sought To demonstrate, it did not imply that the municipality acquired the subjective powers of command in Weberian terms, in order to have the irrigation fees and the officials destined to monitor the distribution of water.

Estudio preliminar de los efectos de las radiaciones gamma sobre los glóbulos rojos humanos; Preliminar study of the effects of gamma radiations on human red blood cells Estrada, E.; Castellini, H.; Acosta, A.; Di Tullio, L.; Borraz, J.; Chinellato, A.; Tack, I.; D'Arrigo, M.; Riquelme, Bibiana Doris; Galassi, Mariel Elisa En este estudio se analizaron los parámetros viscoelásticos y de agregación en glóbulos rojos humanos sometidos a los procedimientos habituales de irradiación gamma con fines transfusionales. Las muestras fueron irradiadas a diferentes dosis a fin de determinar los posibles cambios hemorreológicos que pudieran afectar a la salud de los pacientes y su relación con las modificaciones bioquímicas observadas. Los resultados obtenidos muestran alteraciones en el tiempo de agregación, en la viscosidad superficial de membrana y en el tamaño de los agregados eritrocitarios en las muestras irradiadas, sugiriendo que el daño producido por la radiación ionizante afecta a las propiedades físicas de la membrana del glóbulo rojo en diferentes niveles; In this study, the alterations in viscoelastic and aggregation parameters of red blood cells were analyzed for usual gamma irradiation procedures for transfusion purposes. In order to determine possible hemorheological changes that may affect the health of patients and their relationship with the biochemical changes observed, the blood samples were irradiated at different doses. The results show alterations in the erythrocyte aggregation time, in the membrane surface viscosity and in the size of the aggregates in the irradiated samples, suggesting that the damage produced by the ionizing radiation affects the physical properties of red blood cell membrane at different levels.

Debris flow susceptibility mapping using frequency ratio and seed cells, in a portion of a mountain international route, Dry Central Andes of Argentina Esper Angillieri, María Yanina Debris flow and floods represent one of the main natural hazards that impact transport infrastructure, causing serious damage, economic losses and hinder regional economic development. These processes are eventually associated with massive traffic cuts and direct damage to road structures. To enable the prevention of such consequences, this paper employs statistical modeling techniques, various instability factors and geomorphological mapping to generate debris flow susceptibility maps in a portion of an important route on the Dry Andes of San Juan in the Agua Negra River basin, Argentina. A debris flows inventory map was prepared using satellite images and field checks. The debris flows inventory was randomly divided into a model dataset 80% (47 debris flows) and remaining 20% (12 debris flows) data was used for validation purpose. The instability factors chosen that influence debris flows occurrence were: elevation, slope angle, slope aspect, solar radiation, topographic wetness index, stream power index, topographic position index, Melton ruggedness number, terrain ruggedness index, sediment transport capacity index, plan curvature, profile curvature, lithology, distance to road and proximity to stream. Using these factors, six different models of debris flow susceptibility were calculated by Frequency ratio (Fr). Lithology (igneous complex) was found to be important debris flows-related factor in the study area. The precision of the results was evaluated by receiver operating characteristic (ROC) analysis. According to the area under the curve (AUC) the models of all flow track and natural breaks and all flow track and geometrical interval were 0.83 and 0.84, respectively, showing a practically identical predictive capacity.

The Choiyoi Group in the Cordón del Plata range, western Argentina: structure, petrography and geochemistry Martinez, Amancay Nancy; Gallardo, Adrian Hugo; Giambiagi, Laura Beatriz; Tobares, María Laura El Grupo Choiyoi del Permo-Triásico es una de las suites volcánicas y sedimentarias más conspicuas del sur de Sudamérica, considerada crítica para comprender la evolución geológica de los márgenes occidentales de Gondwana. En este sentido, se examinaron datos petrográficos, geoquímicos y estructurales para dilucidar mejor el carácter físico y las condiciones de emplazamiento de la unidad en el área del Cordón del Plata, dentro de la Cordillera Frontal de Mendoza, Argentina. El sitio es representativo del magmatismo y la deformación a través de diferentes ciclos andinos. Los resultados del estudio indican tres facies litológicas de aumento de la acidez hacia arriba. Las unidades máficas consisten en basaltos, brechas andesíticas y andesítas en la base de la secuencia. Predominan las rocas félsicas, como las riodacitas, los granitos y las tobas soldadas. La zona de falla de La Polcura - La Manga es la característica estructural más prominente de la región, que presumiblemente controla el emplazamiento de brechas e ignimbritas dentro de los miembros medios y superiores. Estas variaciones en la composición sugieren una evolución magmática de la subducción a un entorno de ruptura después de la orogenia de San Rafael en el Paleozoico tardío. En esta línea, se observó que el Choiyoi Inferior cubría las estructuras de San Rafael, lo que indica que la compresión cesó antes de la extrusión volcánica. Los datos de geoquímica indican que las rocas máficas son en su mayoría vulcanitas calcoalcalinos de alto potasio derivados de la cuña del manto por encima de la zona de subducción. En contraste, las rocas felsicas van desde las riolitas con alto contenido de potasio hasta las shoshonitas, típicamente pobres en Eu. Esto indica la fusión parcial de un manto litosférico en una corteza media a delgada.; The Choiyoi Group from the Permo-Triassic, is one of the most conspicuous volcano-sedimentary suites of southern South America, considered critical to understand the geological evolution of the western margins of Gondwana. In this regard, petrography, geochemistry, and structural data were examined to better elucidate the physical character and emplacement conditions of the unit in the Cordón del Plata range, within the Frontal Cordillera of Mendoza, Argentina. The site is representative of the magmatism and deformation through different Andean cycles. Results of the study indicate three facies of increasing felsic composition upwards. Mafic units consist of basalts, andesite and andesitic breccias at the base of the sequence. Felsic rocks such as rhyodacites, granites and welded tuffs are predominant above. The fault zone of La Polcura – La Manga is the most prominent structural feature in the region, which presumably controlled the emplacement of breccias and ignimbrites within the middle and upper members. These compositional variations suggest a magma evolution from subduction to a rifting environment after the San Rafael orogeny in the Late Palaeozoic. In this line, the Lower Choiyoi was observed to overlie the San Rafael structures indicating thus, that compression ceased before the volcanic extrusion. Geochemistry data indicate that mafic rocks are mostly high-potassium, calc-alkaline volcanics derived from the mantle wedge above the subduction zone. In contrast, the Upper Choiyoi corresponds to high-potassium rhyolites to shoshonites, typically depleted in Eu. This indicates partial melting of a lithospheric mantle in an average to thin crust.

Repositioning of the global epicentre of non-optimal cholesterol Irazola, Vilma; Rubinstein, Adolfo Luis; Taddei, Cristina; Zhou, Bin; Bixby, Honor; Carrillo Larco, Rodrigo M.; Danaei, Goodarz; Jackson, Rod T.; Farzadfar, Farshad; Sophiea, Marisa K; Di Cesare, Mariachiara; Asghari, Golaleh; Dhana, Klodian; Gulayin, Pablo Elías; Kakarmath, Sujay; Santero, Marilina; Voortman, Trudy; Riley, Leanne M.; Cowan, Melanie J.; Savin, Stefan; Bennett, James E.; Stevens, Gretchen A.; Paciorek, Christopher J.; Aekplakorn, Wichai; Cifkova, Renata; Giampaoli, Simona; Kengne, Andre Pascal; Khang, Young Ho; Kuulasmaa, Kari; Laxmaiah, Avula High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular risk-changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.

Evaluación del Compromiso Académico y Grit: fortalezas de carácter a desarrollar en estudiantes de postgrado; Assessment of Academic Engagement and Grit: strengths of character to be developed in postgraduate students; Avaliação do Comprometimento Acadêmico e do Grit: forças de caráter a serem desenvolvidas em estudantes de pós-graduação Daura, Florencia Teresita; Barni, María Cecilia; Gonzalez, Mariela Lourdes; Assirio, Juan Alberto; Luquez, Guillermo Gustavo Este trabajo presenta los resultados de un estudio en curso que tiene como objetivo describir los niveles de Compromiso Académico y de Grit de los alumnos, y además, plantear estrategias pedagógicas orientadas a favorecer ambas capacidades en el nivel universitario, siendo uno de los primeros estudios en desarrollar esta temática en Argentina. Para ello, se aplicó una metodología cuantitativa, descriptiva y correlacional, con una muestra seleccionada por conveniencia de 188 estudiantes, los cuales completaron la UWES-SS y la Escala Grit. Los resultados indican que las mujeres presentan mejores índices en las dimensiones del primer instrumento. Asimismo, se encontraron correlaciones positivas y significativas entre las variables según el sexo. Estos hallazgos, relacionados con las diferencias existentes en función de la carrera y de las horas semanales dedicadas al estudio, muestran la importancia de orientar a los alumnos con estrategias concretas.; This paper introduces the results of an ongoing study, aimed at describing Academic Engagement and Grit standards in students attending postgraduate studies. To comply this a quantitative, descriptive and correlational study was applied to a convenience sample of 188 students who filled out the UWES-SS and the Grit Scale. The results showed that women scored better in the Academic Engagement dimensions and the Consistence of Interest factor in the Grit Scale. In addition, significant, positive correlations were found in both constructs. Conversely, no significant differences were found among postgraduate programs, nor among global Academic Engagement and global Grit by program or weekly study time. These findings showed the relevance of guiding students with specific strategies.; Este trabalho apresenta os resultados de um estudo em curso que tem como objetivo determinar a relação entre o Envolvimento Acadêmico e o Grit de alunos argentinos de pós-grão. Para isso, foi aplicada uma metodologia quantitativa, descritiva de correlação, com uma mostra selecionada por conveniência de 188 alunos, os quais completaram a UWESSS e a escala Grit. Os resultados indicam que as mulheres apresentam melhores índices nas dimensões de Envolvimento Académico e no fator Consistência de Interesse da Escala Grit. Da mesma forma, foram encontradas correlações positivas e significativas entre ambas as construções. Pelo contrário, não foram achadas diferenças segundo o pós-grão que os alunos cursam, nem entre os níveis de Envolvimento Acadêmico global e Grit global segundo a carreira e as horas semanais dedicadas ao estudo. Os descobrimentos mostram a importância de orientar os alunos com estratégias concretas

Galectin-1 facilitates macrophage reprogramming and resolution of inflammation through IFN-beta Yaseen, Hiba; Butenko, Sergei; Polishuk Zotkin, Irina; Schif Zuck, Sagie; Pérez Sáez, Juan Manuel; Rabinovich, Gabriel Adrián; Ariel, Amiram During the resolution of acute inflammation, macrophages undergo reprogramming from pro-inflammatory, to anti-inflammatory/reparative, and eventually to pro-resolving macrophages. Galectin-1 (Gal-1) is a bona fide pro-resolving lectin while interferon β (IFN-β) was recently shown to facilitate macrophage reprogramming and resolution of inflammation. In this study, we found Gal-1null mice exhibit a hyperinflammatory phenotype during the resolution of zymosan A-induced peritonitis but not during the early inflammatory response. This phenotype was characterized by reduced macrophage numbers, increased secretion of pro-inflammatory cytokines, such as interleukin-12 (IL-12), and reduced secretion of anti-inflammatory cytokines, such as interleukin-10 (IL-10). In addition, we found a delayed expression of the pro-resolving enzyme 12/15-lipoxygenase in macrophages and heightened levels of the inflammatory protease proteinase-3 (PR3) in peritoneal fluids from Gal-1null mice. Moreover, we observed sex-dependent differences in the inflammatory profile of Gal-1null mice. Notably, we found that IFN-β levels were reduced in resolution-phase exudates from Gal-1null mice. Administration of IFN-β in vivo or ex vivo treatment was able to rescue, at least in part, the hyperinflammatory profile of Gal-1null mice. In particular, IFN-β recovered a subset of F4/80+GR-1+ macrophages, restored IL-12 and IL-10 secretion from macrophages to WT values and diminished abnormal peritoneal PR3 levels in Gal-1null mice. In conclusion, our results revealed a new Gal-1-IFN-β axis that facilitates the resolution of inflammation and might restrain uncontrolled inflammatory disorders.

Una aproximación a la trayectoria profesional de la mendocina Rosario Moreno (1914c- 2010c); An approximation to the professional career of Rosario Moreno (1914c- 2010c); Une approche de la trajectoire professionnelle de la mendocina Rosario Moreno (1914c-2010c) Cremaschi, Veronica El presente trabajo propone una revisión crítica de la historia del artelocal desde la perspectiva feminista a partir de la visibilización de latrayectoria de Rosario Moreno.Esta artista nacida en Mendoza alrededor de 1914, desarrolló su carreraentra América y Europa y fue una partícipe activa en la construccióndel campo cultural provincial, sin embargo su vida y obra han sido muypoco profundizadas por la historia del arte local.Así es que con este trabajo, revisitamos la biografía de Moreno con laintención de resituarla en el contexto cultural de su tiempo. Ello, a lapar de elucidar la trascendencia de su desempeño, evidencia la pocaimportancia que se ha concedido a las figuras femeninas en lahistoriografía del arte provincial y nacional.Como resultado observamos que existe un contraste con la ampliatrayectoria y actividades de la artista en los circuitos legitimadores delas prácticas estéticas, y el pobre reflejo que se observa en la historiadel arte local. Consideramos que este hecho se debe, como hanrescatado distintas/os autoras/es, al silenciamiento que han sufrido lasmujeres en la historia del arte.; This work proposes a critical review of local art history from a feminist perspective, based on the visibility of Rosario Moreno's trajectory. This artist was born in Mendoza around 1914, developed her career between America and Europe and was an active participant in the construction of the provincial cultural field, however her life and work have been very little deepened by the history of local art. So with this work, we revisit Moreno's biography with the intention of placing it in the cultural context of his time. This, while elucidating the transcendence of his performance, shows the little importance that has been given to female figures in the historiography of provincial and national art. As a result we observe that there is a contrast with the wide trajectory and activities of the artist in the circuits that legitimize aesthetic practices, and the poor reflection that is observed in the history of local art. We consider that this fact is due, as different authors have rescued, to the silencing that women have suffered in the history of art.

Activismo y academia: la conversación feminista; Activism and academia: the feminist conversation Fernández Hasan, Valeria El año 2018 marcó para el movimiento de mujeres/feministas argentino una bisagra. Luego de la enorme visibilidad conseguida, producto de la exposición durante el debate por la ley de interrupción voluntaria del embarazo, 2019 se presentó como una oportunidad de repliegue y reflexión. En diversos ámbitos, activistas y académicas, se reunieron a lo largo de los meses bajo la misma consigna: repensar sobre la precipitación de sentidos y prácticas de la marea verde y diseñar estrategias hacia delante en torno a algunos núcleos políticos y teóricos comunes. Analizamos aquí dos encuentros realizados en los extremos del año 2019 con la intención de recoger las marcas de la conversación feminista como gesto político de construcción de acuerdos y de conocimiento colectivo de organización horizontal, circulando, esparciéndose, derramando en grupos heterogéneos de jóvenes recién llegadas al movimiento, pioneras de extensa trayectoria y militantes de distintas tradiciones.; The year 2018 marked a hinge for the Argentine women's / feminist movement. After the enormous visibility achieved, as a result of the exhibition during the debate on the voluntary termination of pregnancy law, 2019 was presented as an opportunity for withdrawal and reflection. In various fields, activists and academics, met throughout the months under the same slogan: rethink about the precipitation of meanings and practices of the green tide and design strategies forward around some common political and theoretical issue. We analyze here two meetings held at the ends of the year 2019 with the intention of collecting the marks of the feminist conversation as a political gesture of construction of agreements and collective knowledge of horizontal organization, circulating, spreading, spilling into heterogeneous groups of young people newly arrived at movement, pioneers of extensive experience and militants of different traditions.

Las Casas de Sal: espacialidad y afecto en las memorias de las infancias en el exilio; As Casas de Sal: espacialidade e afetividade nas lembranças das infâncias no exílio; The Salt Houses: Spatiality and Affection in the Memories of Childhoods in Exile Chmiel, Fira En este texto presento algunos avances de mi investigación doctoral en curso, en la que exploro, desde una perspectiva biográfica, las memorias de quienes tuvieron la experiencia de haber sido niños y niñas durante el exilio forzado de las últimas dictaduras en Uruguay y en Argentina. En esta oportunidad, me centro en indagar algunas articulaciones sobre memoria, espacio e infancia, que emergen de los recuerdos de ?aquellos? niños y niñas. En particular, en la casa como espacio en el que se conjugan diversos sentidos y formas iniciales de vínculo e intimidad. Estos recuerdos puestos en relato, abren nuevos accesos para comprender no solo el lugar de los niños y niñas de entonces en el los tránsitos del exilio, sino también, los sentidos que se son reelaborados en el presente.; Neste texto, apresento alguns avanços em minha pesquisa de doutorado em andamento, na qual exploro, de uma perspectiva biográfica, as memórias daqueles que tiveram a experiência de ter sido crianças durante o exílio forçado das últimas ditaduras no Uruguai e na Argentina. Nesta ocasião, concentro-me em investigar algumas articulações sobre memória, espaço e infância, que emergem das memórias dessas “crianças”. Em particular, na casa como um espaço no qual vários sentidos e formas iniciais de vínculo e intimidade são combinados. Essas memórias contadas abrem novos acessos para entender não apenas o lugar das crianças daquela época nos trânsitos do exílio, mas também os sentidos que são retrabalhados no presente.; In this text I present some progress in my ongoing doctoral research, in which I explore, from a biographical perspective, the memories of those who had the experience of having been children during the forced exile of the last dictatorships in Uruguay and Argentina. In this opportunity, I focus on investigating some articulations on memory, space and childhood, which arise from the memories of “those” children. In particular, in the house as a space where several meanings and initial forms of bond and intimacy are combined. These related memories open new accesses to understand not only the place of the children of that time in the transits of exile, but also the senses that are reworked in the present.